Basic Information

Insect: Megachile rotundata
Gene Symbol: -
Assembly: GCA_000220905.1
Location: NW:743763-747224[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0011 0.067 12.9 0.3 1 23 109 131 109 131 0.94

2 12 2.7e-07 1.6e-05 24.2 1.6 2 23 138 159 138 159 0.97

3 12 6.5e-06 0.0004 19.9 8.9 1 23 191 213 191 213 0.98

4 12 0.0001 0.0064 16.1 4.8 2 23 219 240 218 240 0.97

5 12 0.00028 0.017 14.8 0.1 1 23 245 267 245 267 0.98

6 12 5.6e-07 3.5e-05 23.2 0.9 1 23 275 297 275 297 0.98

7 12 0.17 10 6.0 2.7 1 23 303 326 303 326 0.94

8 12 8.6e-05 0.0053 16.4 0.3 3 23 339 359 337 359 0.96

9 12 4.8e-07 3e-05 23.4 1.8 1 23 365 387 365 387 0.96

10 12 1.3e-08 7.7e-07 28.4 0.2 1 23 393 415 393 415 0.98

11 12 9.8e-08 6e-06 25.6 0.9 1 23 421 443 421 443 0.98

12 12 0.00013 0.008 15.8 0.8 1 21 449 469 449 470 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0011	0.067	12.9	0.3	1	23	109	131	109	131	0.94
2	12	2.7e-07	1.6e-05	24.2	1.6	2	23	138	159	138	159	0.97
3	12	6.5e-06	0.0004	19.9	8.9	1	23	191	213	191	213	0.98
4	12	0.0001	0.0064	16.1	4.8	2	23	219	240	218	240	0.97
5	12	0.00028	0.017	14.8	0.1	1	23	245	267	245	267	0.98
6	12	5.6e-07	3.5e-05	23.2	0.9	1	23	275	297	275	297	0.98
7	12	0.17	10	6.0	2.7	1	23	303	326	303	326	0.94
8	12	8.6e-05	0.0053	16.4	0.3	3	23	339	359	337	359	0.96
9	12	4.8e-07	3e-05	23.4	1.8	1	23	365	387	365	387	0.96
10	12	1.3e-08	7.7e-07	28.4	0.2	1	23	393	415	393	415	0.98
11	12	9.8e-08	6e-06	25.6	0.9	1	23	421	443	421	443	0.98
12	12	0.00013	0.008	15.8	0.8	1	21	449	469	449	470	0.96

Sequence Information

Coding Sequence: ATGCCGATTGACTGTTTAGATGCTACTCTTATACCTGATTGTACGTGGTTGGACTCGAAAAGTTCTCGAACTTTATTTTGTTCGTTTGGTGCTCGAGGATTGTTAAGATACCTTGTTTTgTACGACCGCACGTCCGAAGACTATTATCCGATGGCAATGTTGACGAAGCTCGAGCTGGTGAAAAAGGACACCAATACGGACGCGGCCAAGAAAAGCCCTACATCAGCGACGGGTAACGACACGACGCCGGCCAACAGCCAGCCGCAGAATTTCATCAAGCAGGAGGTGAACGACGAGGACGACGAAGAGGATCTACCGCTGGCGTACCACTGCAAGCTCTGCGGCGTGTTCTTCGCGTCTCAAGCCTTGCTGGACAATCACGAGATCGAGCACAAGGGTAAACGCAAGAACACCTGCGCCCAGTGTGGACGCGTGTTCCGAACGTACGTGAACTTGCGGAAGCACATGAAGAAACACGCGAGCCGCAAGAGTGGTCGCAAAGGAGGCAGCGGTTCGGTCGTCAACCGTTCGTCCAATCTGAAGGTGAAGAAGGAGAAGACAGAACTAGAGTTCCACTGTAAAACGTGCAACAAGGTGTTCCGGCATAAAAGCAATTACCAGAAGCATCTGATGCGACACACCGTGGGCGACCTAACCTGCAAACACTGTCCCAAGAAGTTCCGTTTGTTCCGTGACCTGACTAGGCACGAGAAGACGCACTTCTACCCCAGCTACGTGTGCAAGGAGTGCGACTACGAGACCACCGTGTTGGCAGCACTGAGCATACACATGCTGCGGCACACGGACAAGGCCGACCTGCCCTTCAAGTGCAACGACTGCGACAAACGTTTCCGCAAGGCGATAGATCTGCAGGAGCACTATAACATCCACTCCGGAGACCAGCCGTTTGTCTGCCAGTTGTGCAACAGCGCCTTCTACCTGAGACGACAGTTGTCGGCTCACTGCAGGCGCATGCATCCGGAGATGAAGGCCAACAAGGTAACCAGCACCGCCTGCGATATTTGTGGTCGAGTCCTAGCCACGAAGAGATCCCTGTTCCGTCACAAAGAGAGCCACAATCCCACCAAGCTGTACCTCTGCGACTACTGTGGCAAGAGTCTGAGCAGCGCGGAGCACCTGAAGAAGCACAGACGCATCCACACCGGCGAGAAACCGTACGTCTGCGATATCTGTGGCAAGGGATTCACCGATTCGGAGAACCTGAGGATGCACAGGAGGGTGCACACCGGAGAAAAACCGTACAAATGTGACCAGTGCCCGAAGGCGTTCTCCCAGAGGTCCACCTTGACGATCCACAGGCGAGGACACACGGGAGAACGACCTTACGTCTGTCAGATCTGCAACCGTGGCTTCTCCTGCCAGGGCAACCTGACGGCTCACCAGAAATCCACCTGCGTTTAA
Protein Sequence: MPIDCLDATLIPDCTWLDSKSSRTLFCSFGARGLLRYLVLYDRTSEDYYPMAMLTKLELVKKDTNTDAAKKSPTSATGNDTTPANSQPQNFIKQEVNDEDDEEDLPLAYHCKLCGVFFASQALLDNHEIEHKGKRKNTCAQCGRVFRTYVNLRKHMKKHASRKSGRKGGSGSVVNRSSNLKVKKEKTELEFHCKTCNKVFRHKSNYQKHLMRHTVGDLTCKHCPKKFRLFRDLTRHEKTHFYPSYVCKECDYETTVLAALSIHMLRHTDKADLPFKCNDCDKRFRKAIDLQEHYNIHSGDQPFVCQLCNSAFYLRRQLSAHCRRMHPEMKANKVTSTACDICGRVLATKRSLFRHKESHNPTKLYLCDYCGKSLSSAEHLKKHRRIHTGEKPYVCDICGKGFTDSENLRMHRRVHTGEKPYKCDQCPKAFSQRSTLTIHRRGHTGERPYVCQICNRGFSCQGNLTAHQKSTCV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00866161;
90% Identity: iTF_00216543;
80% Identity: -