Bcon006208.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Bombus confusus
Gene Symbol
ZBTB41
Assembly
GCA_014737475.1
Location
JACXIV010000015.1:2079143-2080420[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.0012 0.091 13.1 0.3 1 23 60 82 60 82 0.94
2 12 2.9e-07 2.2e-05 24.4 1.6 2 23 89 110 89 110 0.97
3 12 2.6e-06 0.0002 21.4 6.0 1 23 143 165 143 165 0.95
4 12 0.00011 0.0087 16.3 4.8 2 23 171 192 170 192 0.97
5 12 0.00043 0.033 14.4 0.1 1 23 197 219 197 219 0.98
6 12 6.1e-07 4.7e-05 23.4 0.9 1 23 227 249 227 249 0.98
7 12 0.04 3.1 8.3 2.0 1 23 255 278 255 278 0.94
8 12 9.3e-05 0.0072 16.5 0.3 3 23 291 311 289 311 0.96
9 12 5.3e-07 4.1e-05 23.6 1.8 1 23 317 339 317 339 0.96
10 12 1.4e-08 1.1e-06 28.6 0.2 1 23 345 367 345 367 0.98
11 12 1.1e-07 8.2e-06 25.8 0.9 1 23 373 395 373 395 0.98
12 12 0.00014 0.011 16.0 0.8 1 21 401 421 401 422 0.96

Sequence Information

Coding Sequence
ATGTTGACGAAGCTCGACCTGGTGAAGAAGGACGCGAATCCAGAGAGTTCGGCGCCTGCGAAATCCGCGGATGCGGCTGGTGGCAACAACACGAACATTCTGCCGATGAATCAGGAGCAAAACTTCATCAAGCAAGAAGTAAATGACGAGGACGATGAAGAGGATCTGCCACTGGCTTATCATTGCAAACTGTGTGGCGTGTTTTTTGCCTCTCAGGCGCTGCTGGACAATCACGAGATCGAGCACAAGGGTAAACGCAAGAACACTTGCGCCCAATGCGGAAGAGTCTTTAGAACGTACGTAAATCTACGTAAACACATGAAGAAGCATACAGGTCGCAAGGGTGGACGCAAAGCGAGCAATACTTCAACGGTAGCCAATCGTTCGACCACGCTGAAGGTAAAGAAAGAGAAACCGGAGTTGGAGTTTCTGTGTAAAACGTGCAACAAGGTATTCCGACACAAGAGTAATTATCAGAAGCATCTAATGCGACACACGGTTGGCGATCTAACTTGCAAACACTGTCCTAAGAAGTTCCGTCTGTTCCGTGATCTGACCAGGCACGAGAAGACTCACTTCTACCCCAGCTACATGTGCAAAGAATGCGACTACGAGACTACAGTGTTAGCAGCGTTGAGCATTCACATGTTGCGACACACGGATAAGGCGGACCTTCCCTTTAAATGCAACGACTGTGACAAACGTTTCCGTAAAGCGATAGATCTACAAGAGCATTACAATATACATTCTGGAGACAAGCCTTTCGTTTGTCAGTTATGCGGTAGCGCCTTCTATCTGAGACGACAGCTCTCTGCCCACTGCAGACGTATGCATCCTGAAATGAAGGCTAATAAGGTAACCAGCACGGCCTGTGACATTTGCGGTCGTGTCTTGGCTACCAAAAGATCCTTGTTCCGTCACAAGGAGAGCCACAATCCTACGAAACTGTATTTGTGTGATTATTGTGGCAAGAGTCTTAGCAGCGCTGAACATTTGAAGAAACACAGGCGCATCCATACTGGCGAGAAACCATATGTTTGTGACATATGTGGTAAAGGTTTCACAGATTCAGAGAATCTCAGAATGCACAGGAGGGTGCATACTGGTGAAAAACCGTACAAGTGTGACCAGTGTCCAAAAGCTTTTTCACAGAGATCCACGTTGACTATACACAGGCGAGGTCATACAGGAGAACGACCGTACGTGTGCCAGATCTGCAACCGTGGCTTCTCATGCCAGGGCAACTTAACAGCTCACCAGAAGTCGACCTGCGTTTAA
Protein Sequence
MLTKLDLVKKDANPESSAPAKSADAAGGNNTNILPMNQEQNFIKQEVNDEDDEEDLPLAYHCKLCGVFFASQALLDNHEIEHKGKRKNTCAQCGRVFRTYVNLRKHMKKHTGRKGGRKASNTSTVANRSTTLKVKKEKPELEFLCKTCNKVFRHKSNYQKHLMRHTVGDLTCKHCPKKFRLFRDLTRHEKTHFYPSYMCKECDYETTVLAALSIHMLRHTDKADLPFKCNDCDKRFRKAIDLQEHYNIHSGDKPFVCQLCGSAFYLRRQLSAHCRRMHPEMKANKVTSTACDICGRVLATKRSLFRHKESHNPTKLYLCDYCGKSLSSAEHLKKHRRIHTGEKPYVCDICGKGFTDSENLRMHRRVHTGEKPYKCDQCPKAFSQRSTLTIHRRGHTGERPYVCQICNRGFSCQGNLTAHQKSTCV