Basic Information

Insect: Megachile ligniseca
Gene Symbol: ZFX
Assembly: GCA_945859565.1
Location: CAMAOB010000007.1:444038-448306[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1.2 1.2e+02 3.7 0.1 3 23 24 44 23 44 0.94

2 15 4.1 4.2e+02 2.1 4.2 1 23 881 904 881 904 0.81

3 15 0.0011 0.11 13.3 2.2 3 23 987 1008 985 1008 0.96

4 15 0.0078 0.81 10.6 0.1 2 23 1021 1042 1020 1042 0.97

5 15 1.5e-05 0.0015 19.2 3.1 2 23 1045 1066 1044 1066 0.97

6 15 0.0066 0.68 10.8 0.7 1 23 1072 1094 1072 1094 0.95

7 15 2.4e-05 0.0024 18.5 4.5 2 23 1101 1122 1100 1123 0.95

8 15 0.32 33 5.6 3.7 5 23 1136 1154 1135 1154 0.97

9 15 2.1e-05 0.0022 18.7 1.5 3 23 1161 1182 1160 1182 0.97

10 15 0.0097 1 10.3 0.3 2 23 1198 1218 1197 1218 0.97

11 15 6.5e-05 0.0066 17.2 0.7 1 20 1224 1243 1224 1246 0.92

12 15 8e-05 0.0083 16.9 2.7 1 23 1254 1276 1254 1276 0.99

13 15 0.0032 0.33 11.8 3.4 1 23 1282 1304 1282 1304 0.97

14 15 4.1e-06 0.00042 20.9 3.9 1 23 1310 1332 1310 1332 0.99

15 15 0.0014 0.14 13.0 6.3 1 23 1338 1360 1338 1361 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1.2	1.2e+02	3.7	0.1	3	23	24	44	23	44	0.94
2	15	4.1	4.2e+02	2.1	4.2	1	23	881	904	881	904	0.81
3	15	0.0011	0.11	13.3	2.2	3	23	987	1008	985	1008	0.96
4	15	0.0078	0.81	10.6	0.1	2	23	1021	1042	1020	1042	0.97
5	15	1.5e-05	0.0015	19.2	3.1	2	23	1045	1066	1044	1066	0.97
6	15	0.0066	0.68	10.8	0.7	1	23	1072	1094	1072	1094	0.95
7	15	2.4e-05	0.0024	18.5	4.5	2	23	1101	1122	1100	1123	0.95
8	15	0.32	33	5.6	3.7	5	23	1136	1154	1135	1154	0.97
9	15	2.1e-05	0.0022	18.7	1.5	3	23	1161	1182	1160	1182	0.97
10	15	0.0097	1	10.3	0.3	2	23	1198	1218	1197	1218	0.97
11	15	6.5e-05	0.0066	17.2	0.7	1	20	1224	1243	1224	1246	0.92
12	15	8e-05	0.0083	16.9	2.7	1	23	1254	1276	1254	1276	0.99
13	15	0.0032	0.33	11.8	3.4	1	23	1282	1304	1282	1304	0.97
14	15	4.1e-06	0.00042	20.9	3.9	1	23	1310	1332	1310	1332	0.99
15	15	0.0014	0.14	13.0	6.3	1	23	1338	1360	1338	1361	0.96

Sequence Information

Coding Sequence: ATGCATAAACAAAATATCGCAGACACAATGGATGCAACGAGCAATGGAACATCAGGGAGTACAATGGCTTGTCCAGTGTGTACCCTCTACTTACGTGAGGGTATCAGCTTACAGAGACATTTGGACACTCATCCTAAAGAACAAGTCATTGAAGCTCTTATCAAAGCTAGTACTAATTCGATACATTTGCAACAAACTCAGTTGTCACCATCCGCGCCTCCAGCATCTCCAGCTATACAATCACCACAAAGTACATCTCAAGTTACACAGAATACTCATGTATCGGCTCAATCTCCATATCCTATAGGACCTATTTTCGAATGTCCACCCATTGGCACTGTAATGCCACCCCAGTTTGCTTCGTTCAGTTATCAGCAGTTTGTAAATAATGGCACTATGATGATACCACAATACGCGATGGGTCCACAAGCTAATCAGATGATGCAGATGCTTTATAATCCATATGGCATGTACCAGCAACAACAGATTCCGACTGTTCAGATGATCTCACCAGTTACAACTATATCGAACACAGCAAGAATTAGGCCAGTGGTGACTATGGCTGGTGAAACAAGCAGTAGAACTGCCATTGCTGTGTCTGTAAATAATTCCGAGCCAAAACAAATTTTACCTGAAATTTTACCTGAGTCAGAGCAAGAGTCTAAACAAGTGTTACCAGATATCAATCTTCCAGTTTCTCCTCCATCGTTGAATGAGGATAATTCTATACAACAAAATGAAAATGGAACTAGTACAATTCAAATAGAGCATGTGGAAGAACCTCATGGTTCAAGCACTGATCATCAGCATAATATACAAAATGAATATGATAGCATTCCAAAAACATTAGAAATCACTTGTAATGTTGTTGATACTAGTGATGATAAAGTTGAGAGTGTATTACCAGATATCGATGATGGAGAATCATCACATGTTATCACTGCAGATGTTCAGTGTAAATCCATTCATTATGAATCGTCAGAGATGCAAGAATACGTGCAGAGATATAAAGATGATAATGATAGTAGTAAAATTATCATGCCTGAGATATCCATGGTAAGTGAGAGTGAAACTGAAAAAACAACTAATGAAAAAGTTCCTCACAGAAAAGAGATAAATGAAAATCAAGGTACCTCATCTGAAATGCCTATAAGAGATACAATAAAAGAATCAGCTCAACCTCAAGTAGAACAATTAGAGCACCTTTTAATCACTATTGTGGAATCTGAATTTAATAGTGAATCACAAAAACAATCTGATGACAAAAAGAAAGATGAAGTTTTGGAACCAAAATCTTCCCCTGAAAGAGCAGAAAGTGTAATTCATGAAACTAGTAATCCGGTTGAACATGATAGCAGTTATAAACCTGACATAGAAATAAAGATGAATGAGAGTTCAGAAAATTATCTAGATAGTGATGAAAATAAAAATTCTTGTCTTTTGTATCATTATAAAAACAGTTTATCTGCACCTGCATCACCAGCGGTACAAAAAAAGTATAGGACATATTCAGTTCGTTCAGACTTTGGATCAAATGAAACTCTTAATTCTTATCCAATTGGTTTTGATGCAAATACATTGCAAGATGAAGATGAAGAGGATGAAAAAAATGAAGCGGAAGATAATTTTGATGAGGCAGATATGGAGATAGAAGAAATACCTAGCCCACACACACCTTTTGCTAAATATGGAGAAAGTACAGATCATATTAGATCACATACTCCATTATCTGTAAGTAGTGGTATCTCTGTATTGAGAGTTAGAAAAGATCTCAGTAAACCATGCTCACCTGCATCAGTACATTCATTTTGTCATATGGATGCTAATGATATAAGTCATGATGAAGAAAGTAATGCAGCAATGGATGTATCTCCAGAAAAAGATCCTATTGATTGTTCTTCAATTGAACAAGATGTAAAAGCTGATCAATCAGAACTTTCTATATGTGAAAATGAAAAGAAAGTAGTAGACACAGCATATCAGTCTGTAATTACTGAACATGTGAGTTCATTTCCTACAATTCATTCTCAACAATCAACATCGATAGATGAGTCATATAATGCAACAAATAAAAGTCATAATCTTGTAAATTTGTCAGAATCTAGTGATATTGCAAGTAGTTCTGATTCAAAAAGCTTTCACTCATCTAAATCAATTATACAAAAGCAATCGGTGGAACTTCTTAGTTTAAACGAGGATGCTCATGCAGGTCCAATGAATATGTTTGAATTAGATGGTCTTCAAATATTAGTTCCTAGTACATTTATAAGTGATTCTTCACAAAAAGCTGTTAGTGCAACCAGTCAACAGTCTATGGCAAGTAGTGAAGGAGGAATAGGTGTAGATGAAGAAGTGAAAAGTATTAACATGAGGGCTGATGAAACTATGCCACCTAGAGGTGAATTATCAGAACAGGAAAGCAATGGATGTACAGAGCAATCAGCTTGGCAGTTGTATGCTGGTCAAGAATCATCACGTATGTCAACCTCTTATGATTTGATGGCACGTGAAAGTTGGGAAGAATCCGAAGGATCAGACAATGAAATTAGTGGTCCCTTATTAGATAGCAGATCTTTAGCCACACATTTTACATCAAGTTTATTCTTAGATCGAGATAGAAAAACACCGACAAAAAGAACATTTAAATGTTACCATTGCCCAGAAACATTTGATTGTCCGAAAGAACGCCGAGTACACAGTACTACCGTGCATCAAGAAGCCGGACCCAGTAGCAGTAGAGAATCAACGGATCAACCTGAAGTGAAGGATATTAAGTTACTTGATGGTCGCATGAATGCATTTGACGATTTTTTTGTACCGGGTTTACACGTTCAACAAACTTACCATCAACCACTTTTACATCAACTCCAACCACCGCAATCATCGGAATTAACAACAAAAGTAGAACCTGATCAAAAAATCGAAACGTTGGTAATACCATCGAATATTGAGGTGATTTGTACACTTTGTAATCAAAGATTTAGTAGTGAAAAATCGTTACAATTACATCATAAAAGAGTACATGTTACAGAAACAGCGAAAAGAATTCGAGAGAGTACTAAGTGCCAGATATGTAACGAAGAATTCCCTTCGGTTTTACTGTTTAATGCCCACCTAAAAATACATCCGTTAGAATGTAGCCAGTGTGGGAAGTATTTTTATAGGAAACAAAATTTTAAATTACATATGAAACGACACCTAGGAATCAAACCATTTCCGTGTACCGTTTGCGACAAAACATTTTTGACAAAACAAAAATTAGACGAGCATACCAATGGCCATACCGGGAATGCACCTGTCAAGTGTAATCTTTGCAATGAAACGTTTCGCAGATATTCAAATTTGACACAGCACAAAAACAGACATCACTTGAACATAAAAAAGAAATTGAAGGATTACATATGTCACTGTGGTGAGATATTTCATACAAAGAAGAAATTAGCCTGGCATAAGGAAACACACGATGAAAAACCAAAAGCATGTACATACTGTAACGAAAGATTCATTCACATGGCTAGCTTGACTCGACACATGCGTCGAGCTCATAACAGAAGATTTGTTCCCGATGCTCAAAGGGAAAACGAAAACGTTGAATGTCCCATATGTAAGTGTATTTATTTGCGATCTTCCTTAGCAGTACATATGCGAGTTCACAATGGCGAAAGACCATACGAATGTCAAGTTTGCTCGAAGGCATTTAGTACTAAGTGGAATTTACAATTGCACAAATGGACTCACGCTGCTCGTAGCACCAAACCCTTTAAATGTAATCAGTGTAGTGCCGCGTTTTACCGGCACAGCGATTACACTGCTCATATGAATTCCCATAGAAATGTGCGTCCTTTTACCTGCAATTACTGCGGTGCGCAATTCATACGAAAGTATAATTGTTTAAGGCATGTGAAGGAACACGAAGAAAGCAAAGCGTATACATGCGATGTTTGCAACAAAACGTTTCATAGGTCATATTATCTGAAAGAACACTTGCGAGTACATTCAGGTGCCAGACCATATACATGTCATATTTGTGGAAAGTCTAGCGGTACGAAATCCAATCACAATAAACATGTCAGAATTCATCATGCACGCGAACCTGTAAATACCGAAAATTAA
Protein Sequence: MHKQNIADTMDATSNGTSGSTMACPVCTLYLREGISLQRHLDTHPKEQVIEALIKASTNSIHLQQTQLSPSAPPASPAIQSPQSTSQVTQNTHVSAQSPYPIGPIFECPPIGTVMPPQFASFSYQQFVNNGTMMIPQYAMGPQANQMMQMLYNPYGMYQQQQIPTVQMISPVTTISNTARIRPVVTMAGETSSRTAIAVSVNNSEPKQILPEILPESEQESKQVLPDINLPVSPPSLNEDNSIQQNENGTSTIQIEHVEEPHGSSTDHQHNIQNEYDSIPKTLEITCNVVDTSDDKVESVLPDIDDGESSHVITADVQCKSIHYESSEMQEYVQRYKDDNDSSKIIMPEISMVSESETEKTTNEKVPHRKEINENQGTSSEMPIRDTIKESAQPQVEQLEHLLITIVESEFNSESQKQSDDKKKDEVLEPKSSPERAESVIHETSNPVEHDSSYKPDIEIKMNESSENYLDSDENKNSCLLYHYKNSLSAPASPAVQKKYRTYSVRSDFGSNETLNSYPIGFDANTLQDEDEEDEKNEAEDNFDEADMEIEEIPSPHTPFAKYGESTDHIRSHTPLSVSSGISVLRVRKDLSKPCSPASVHSFCHMDANDISHDEESNAAMDVSPEKDPIDCSSIEQDVKADQSELSICENEKKVVDTAYQSVITEHVSSFPTIHSQQSTSIDESYNATNKSHNLVNLSESSDIASSSDSKSFHSSKSIIQKQSVELLSLNEDAHAGPMNMFELDGLQILVPSTFISDSSQKAVSATSQQSMASSEGGIGVDEEVKSINMRADETMPPRGELSEQESNGCTEQSAWQLYAGQESSRMSTSYDLMARESWEESEGSDNEISGPLLDSRSLATHFTSSLFLDRDRKTPTKRTFKCYHCPETFDCPKERRVHSTTVHQEAGPSSSRESTDQPEVKDIKLLDGRMNAFDDFFVPGLHVQQTYHQPLLHQLQPPQSSELTTKVEPDQKIETLVIPSNIEVICTLCNQRFSSEKSLQLHHKRVHVTETAKRIRESTKCQICNEEFPSVLLFNAHLKIHPLECSQCGKYFYRKQNFKLHMKRHLGIKPFPCTVCDKTFLTKQKLDEHTNGHTGNAPVKCNLCNETFRRYSNLTQHKNRHHLNIKKKLKDYICHCGEIFHTKKKLAWHKETHDEKPKACTYCNERFIHMASLTRHMRRAHNRRFVPDAQRENENVECPICKCIYLRSSLAVHMRVHNGERPYECQVCSKAFSTKWNLQLHKWTHAARSTKPFKCNQCSAAFYRHSDYTAHMNSHRNVRPFTCNYCGAQFIRKYNCLRHVKEHEESKAYTCDVCNKTFHRSYYLKEHLRVHSGARPYTCHICGKSSGTKSNHNKHVRIHHAREPVNTEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00962003;
90% Identity: iTF_01122626;
80% Identity: -