Basic Information

Insect: Megachile leachella
Gene Symbol: GLIS3
Assembly: GCA_963576845.1
Location: OY756261.1:9717719-9727923[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.00057 0.085 14.3 0.2 1 23 288 313 288 313 0.97

2 5 0.4 60 5.3 0.1 5 23 359 379 353 379 0.79

3 5 1.7e-06 0.00026 22.2 1.0 2 23 386 409 385 409 0.97

4 5 9.2e-05 0.014 16.8 2.4 1 23 415 439 415 439 0.96

5 5 3.3e-06 0.00049 21.3 0.3 1 23 445 469 445 469 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.00057	0.085	14.3	0.2	1	23	288	313	288	313	0.97
2	5	0.4	60	5.3	0.1	5	23	359	379	353	379	0.79
3	5	1.7e-06	0.00026	22.2	1.0	2	23	386	409	385	409	0.97
4	5	9.2e-05	0.014	16.8	2.4	1	23	415	439	415	439	0.96
5	5	3.3e-06	0.00049	21.3	0.3	1	23	445	469	445	469	0.95

Sequence Information

Coding Sequence: ATGCACCTCGAGGATTACCATGTGAACAGAAACGAGGAGGACGTGCAACGAGCCTGTTCCAAGGTCATCAAACAAGAGGATTTCAACAGTTTGCATTTGGCGCCGATAAATGGTGTCGGTCAGCAACCTTGTTGGGTCACATCTCATCCGGATAATGTCACCTCTCCCTTTTTGGCGAACAACTCCAGTCCGGATTGGGAGCAACTCACCACCGTGTTCCAGCTGGAGTTCCAGTACCCATGTCAACAATACCCGCCAACAGACAGGTCTCCAGGAAGCACTGGAAGCGAAGCAACCACTCCAACATGGGTCATCCACAACCACGACACGTCTGACAATTCTCAAAGGTTACCTCCAGTCGGTTCAGCATTCTCTTTCTCGAGGACCTTCAGCAATCCTGTGTACACGGAATACCAAGGCTACCAGGAGTACCAGGATGACGCGTCCGTGTCATTACCGTTGGTTCTGCACAACCAATCGGAGGACCAAGGATTCACAGGCACCATGCAAGCAGCAACGGACGAATTTGATCTCAGTTTAATCAGAGGCGATCCCACGTCGTTGTTGTGCAACGATTCACCTTCTTCGCCGTCCTCCAGCTATCTTGAAGAGCTACAGGATCCCTTCGCGAATTTAAATGGACCCTACGCCGTTGGACACCTGGTTTCTGGGCAACAGTCCGCAGTTACGGGAATGAATTATGCTAATGACGTTTTGAacgagggatttgggaatcagATTGTTCTACCGAGGAACGAGGGACTTCTGCTGACCGATAGACGCGTGCCCCTCGGAAAAGCTGAGGACGTGAAAGGGAAAGCTTATGACTGTTCAACGACGGACGACAATTTAACGTCGACGTATCAGTGCCGATGGATAGATTGCGGCTGCGCCTTCGCCGAGCAAGAGGGTTTAGTGCGGCACATCGAGAGACGACACGTGGAGTCCTCGTCATCGAACGCGCACGGACACGGCAGACGGATCCAGAGGGACAGAGACAAGGATAAGGATAAGGACACCGACGGATTCCCGAATTCTGTAAGCGGTCAGGACGAGTTCGCGTGCCTTTGGCAAGGATGTCCGCGTGCCAGACCGTTCAATGCCAGATACAAGCTGTTGATCCACATGAGGGTGCATAGTGGCGAAAAACCGAACAAGTGTCCGTTTACAGGATGCAAGAAAGCATTCTCCCGATTGGAAAACCTGAAAATCCATCAGAGATCGCATACCGGAGAACGACCCTACGCCTGTCAGCATCGCGGTTGCACGAAAGCGTTTAGCAACAGCAGCGATCGTGCGAAACATCAGAGGACACATTACGATACGAAACCATACGCATGCCAAGTAAGTGGTTGCGGCAAACGATACACGGATCCGTCGAGCCTACGAAAGCACGTGAAGAATCACACGGAGCCAACGACGACTCTATCTAATCTCTCGTTAACGTCCGAGAGCAAAGTAACCGTTGTATCCAATAATTCGAGACAAGATCCGATTTCCACGGCGACGAAACATCAGCAAGCTCAAACGCCGCTGCCATATCACAGGGAATCGAATTACCGGACGTATAAGACTTCGGAGTCTTACGCGGACGAGGACGCGGACCTGTTCCAAACGAATCTGTGTCAGGTCGATAGGATTTCTATGAACCTTGACAGTAATCAGGAGTATGTGCCTATCGAGTCTGTCAAGCGTTTTCTCATCGATGATGTCAGCACGCACGTGGACGGCACAGTATACCATGTTGAAGACGAGGTTCCCGATTTCAACGAGCTGGGTGCCGACATCGAACAACAGTTTCTCGAATTGAGCAACTTGAACGACACCGTGTTCATCGACGGTTAA
Protein Sequence: MHLEDYHVNRNEEDVQRACSKVIKQEDFNSLHLAPINGVGQQPCWVTSHPDNVTSPFLANNSSPDWEQLTTVFQLEFQYPCQQYPPTDRSPGSTGSEATTPTWVIHNHDTSDNSQRLPPVGSAFSFSRTFSNPVYTEYQGYQEYQDDASVSLPLVLHNQSEDQGFTGTMQAATDEFDLSLIRGDPTSLLCNDSPSSPSSSYLEELQDPFANLNGPYAVGHLVSGQQSAVTGMNYANDVLNEGFGNQIVLPRNEGLLLTDRRVPLGKAEDVKGKAYDCSTTDDNLTSTYQCRWIDCGCAFAEQEGLVRHIERRHVESSSSNAHGHGRRIQRDRDKDKDKDTDGFPNSVSGQDEFACLWQGCPRARPFNARYKLLIHMRVHSGEKPNKCPFTGCKKAFSRLENLKIHQRSHTGERPYACQHRGCTKAFSNSSDRAKHQRTHYDTKPYACQVSGCGKRYTDPSSLRKHVKNHTEPTTTLSNLSLTSESKVTVVSNNSRQDPISTATKHQQAQTPLPYHRESNYRTYKTSESYADEDADLFQTNLCQVDRISMNLDSNQEYVPIESVKRFLIDDVSTHVDGTVYHVEDEVPDFNELGADIEQQFLELSNLNDTVFIDG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00684996;
90% Identity: iTF_00964697;
80% Identity: -