Mlea026839.1
Basic Information
- Insect
- Megachile leachella
- Gene Symbol
- -
- Assembly
- GCA_963576845.1
- Location
- OY756259.1:5262651-5265308[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 5.3 7.9e+02 1.8 0.9 1 10 312 321 312 334 0.76 2 15 0.007 1 10.9 1.3 1 23 342 365 342 365 0.92 3 15 0.093 14 7.3 4.2 1 22 371 392 371 395 0.89 4 15 0.088 13 7.4 5.3 1 23 477 499 477 499 0.93 5 15 0.008 1.2 10.7 0.5 1 23 506 529 506 529 0.91 6 15 0.00096 0.14 13.6 3.1 1 23 535 557 535 557 0.97 7 15 8.7e-05 0.013 16.8 2.3 1 23 563 585 563 585 0.99 8 15 4.8e-06 0.00072 20.8 2.2 1 23 591 613 591 613 0.98 9 15 0.0012 0.17 13.3 0.1 1 23 626 649 626 649 0.95 10 15 0.00014 0.02 16.2 4.3 1 23 665 688 665 688 0.96 11 15 0.0003 0.045 15.2 0.8 1 23 696 719 696 719 0.98 12 15 0.00063 0.095 14.1 0.7 1 23 725 747 725 747 0.97 13 15 0.00049 0.073 14.5 5.2 1 23 753 775 753 775 0.98 14 15 4.1e-06 0.00061 21.0 1.5 1 23 781 804 781 804 0.98 15 15 0.00034 0.051 15.0 0.9 2 23 809 830 809 830 0.97
Sequence Information
- Coding Sequence
- ATGGATACAATAAGGAATACATTAATATGTCGTTTATGTGGTGTTAATATTGTAGaaggaaaatgtaaaaacaTTTTCGAAGGATCAACTAATTTGGTACAGAAGataaaagaaacattaccaATTTCAATATCTATAGATGATAATGGTTCAAAACATCTATGCTTGCCATGTTATgacaaaattattctttattacaaatttaccCAAGAAGTATTAGAATATTccaaaaaattagagaatgcgTCAGAAATAAAGTCTTTTTTTGATTTATCCAAAGAAATAACAGacttttcaaaaattcatagTGATGCTGTATATACATGTCCAAATTGCAATGTAGGTTTAATGATTTTATTAGTTAGTAATTCACAAGGCTGTGATTATACCTTTCAAATCTCATTAGCTATGGTAAATCATTCTGAGAAGAAACATGTTATACAAGAGAAAAATATTGAGATACATAAAAACTTAATACATGCCAATAATACTAAGAACAATATATATTCAAAACACGAAAATAAAACAACTTCTGAAAGTGTTGAAAATGTTCCTAATTTAATAAGTCTTACGTTACCTGTATTGCAAcaagaagaaaatataaattatatcaatGTATTATCCAATAAAGAAAATACAGAAACTGAAGAGTGGAAAAagcagaaaaaaaaatttaaagaatctaATTGTTACAACCATTCTATTCATTCATCAAATGTATCCTACACGTCTAATGAGAACCTACTGAACTGTGATTATGATTCTGCAGATCAATTAGTAAAAGTTGAGAATGAAAGTGATAATGCTTATTGGTTTGATAGTGAGACTGACTGTAAAAGCGAAAAAGATGTATATATGACTGAATCACAAGATATTATATTAAAGAAAGATAATGCACAAGAAGAAGATGATTCATATAAGTCTTGTTTAAAATATGAATGCAAATTATGTGGGGCACGTTATCTTTCACATTTAAAGTATGAATTTCATATGGAAAGACATAAGTTAGGTAAAATGTGTAAATATGAATGTACAGTATGTGATAAAGAAACAACTAGTGAAAATTTATTATGGGATCATTATTTTCACACCCATAAAAGTTTACAACGTTATGTTTGCTTAGAATGCGGAAAATTATTTACTAAACGATCTAGATTGAACTGTCATCAAAAGAATTATAAACACTCTGGTATAAAACAAATACAAGTCGATACCAGTAAAGATACTACTGGTGAAGATTTTATACAAAAGGTAATAGCAACAACAAACCAAGAAAAAGTTTCTGTAAACTGTAATCTCTGTGGTAAATTAATTTCAGACCTAGATCCAGATGCTATTAATGATTTAGTTACATGTATTAATTGTGAAGATTCTACACTTTCTTTAATGGTAGATGGAAACGAAACTAAAGTAATCTCTCCAAGACAATATCATTGTTCTAAATGTCCTAAGCATTTTGTACGGAAAGAACGATTAGAATTCCATGAAATGAGACATAATGAGAatatgaatgaatttatttgtaGTACTTGTGGAAAAGATTTTAGAGCTGAAAATTCCTTGTATGAACATTACCTTTTTGTTCATAAAGGAGCAAGACCCCATATTTGTGAATTATGTGGTAAATCGTTTCAATTAAAGGCCAGATTAAAAGAACACCATAGAATTCATACAGGTGAAAGACCATATCAGTGTGATATTTGTGGTCAACGATGTAGAACTACAAATGCCTTAAAACTTCATAGGAAAATTCATTTTTctcataatagatatacttgtaATGTCTGCAATAAATCATTTAGTAAGAAACAAAATATGAATGAACATTTAGAAAAACATtggaaaaatgataaaagtgtAACATTACCACAGCTATTTACATGCCCAATTTGCTTAGAAGATTTTCCGACATATCGAATGTTAAAATACCATATGATAGAAatacatgaaataaataatcaagatcCAATTTTAATTAAGCAAAAGCCATGGTATGAATGCACTGAATGTCATGAAAAGTTCAAGCATCAAATGTCTTTAAAAGCACATAAAGAGAGAGTACATGAAGGAAGAGTAGATCCAAATTACCAATGTGATACTTGTAATGCAACATATAAAGTAAAACAACTTTTAGTGAATCATATTAAAAGCAAACATAATGGTGAAAGACGCTATAAATGTGCACAGTGTGAGAAAGGATTCAATGATACTAAATCTTTATATAATCATGTATTGTTACATACTGGTAAAAAACCATTTGTTTGTGAATATTGTAATATGAGTTTTAGAAGAAAAGACTCTAGAGACCATCATCGTAGAAAACATACAGGTGAACAACCTTATCAATGTCCAGACTGTGGTGAATCATTTTCTACCTATAATAATAGATCTAAGCATCGAAAACGAGAGCATGGAAAAGATCCTGAATGTCCTGAATGTGGAGAAAAGTGTAGTAATCAGCAGGAAATTAGAATTCATCTAAATAAACATCTtggagaaaaattgaaaaaactaaaaaatatacaaCCTGAAATGATATAG
- Protein Sequence
- MDTIRNTLICRLCGVNIVEGKCKNIFEGSTNLVQKIKETLPISISIDDNGSKHLCLPCYDKIILYYKFTQEVLEYSKKLENASEIKSFFDLSKEITDFSKIHSDAVYTCPNCNVGLMILLVSNSQGCDYTFQISLAMVNHSEKKHVIQEKNIEIHKNLIHANNTKNNIYSKHENKTTSESVENVPNLISLTLPVLQQEENINYINVLSNKENTETEEWKKQKKKFKESNCYNHSIHSSNVSYTSNENLLNCDYDSADQLVKVENESDNAYWFDSETDCKSEKDVYMTESQDIILKKDNAQEEDDSYKSCLKYECKLCGARYLSHLKYEFHMERHKLGKMCKYECTVCDKETTSENLLWDHYFHTHKSLQRYVCLECGKLFTKRSRLNCHQKNYKHSGIKQIQVDTSKDTTGEDFIQKVIATTNQEKVSVNCNLCGKLISDLDPDAINDLVTCINCEDSTLSLMVDGNETKVISPRQYHCSKCPKHFVRKERLEFHEMRHNENMNEFICSTCGKDFRAENSLYEHYLFVHKGARPHICELCGKSFQLKARLKEHHRIHTGERPYQCDICGQRCRTTNALKLHRKIHFSHNRYTCNVCNKSFSKKQNMNEHLEKHWKNDKSVTLPQLFTCPICLEDFPTYRMLKYHMIEIHEINNQDPILIKQKPWYECTECHEKFKHQMSLKAHKERVHEGRVDPNYQCDTCNATYKVKQLLVNHIKSKHNGERRYKCAQCEKGFNDTKSLYNHVLLHTGKKPFVCEYCNMSFRRKDSRDHHRRKHTGEQPYQCPDCGESFSTYNNRSKHRKREHGKDPECPECGEKCSNQQEIRIHLNKHLGEKLKKLKNIQPEMI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01123228;
- 90% Identity
- iTF_01123228;
- 80% Identity
- -