Basic Information

Insect: Megachile leachella
Gene Symbol: ZFX
Assembly: GCA_963576845.1
Location: OY756257.1:10921624-10925882[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1.3 1.9e+02 3.7 0.1 3 23 24 44 23 44 0.94

2 15 4.4 6.5e+02 2.1 4.2 1 23 878 901 878 901 0.81

3 15 0.0012 0.18 13.3 2.2 3 23 985 1006 983 1006 0.96

4 15 0.0083 1.2 10.6 0.1 2 23 1019 1040 1018 1040 0.97

5 15 1.6e-05 0.0023 19.2 3.1 2 23 1043 1064 1042 1064 0.97

6 15 0.007 1 10.9 0.7 1 23 1070 1092 1070 1092 0.95

7 15 2.5e-05 0.0038 18.5 4.5 2 23 1099 1120 1098 1121 0.95

8 15 0.34 50 5.6 3.7 5 23 1134 1152 1133 1152 0.97

9 15 2.3e-05 0.0034 18.7 1.5 3 23 1159 1180 1158 1180 0.97

10 15 0.01 1.5 10.3 0.3 2 23 1196 1216 1195 1216 0.97

11 15 6.8e-05 0.01 17.2 0.7 1 20 1222 1241 1222 1244 0.92

12 15 8.5e-05 0.013 16.9 2.7 1 23 1252 1274 1252 1274 0.99

13 15 0.0034 0.51 11.8 3.4 1 23 1280 1302 1280 1302 0.97

14 15 4.3e-06 0.00065 20.9 3.9 1 23 1308 1330 1308 1330 0.99

15 15 0.0015 0.22 13.0 6.3 1 23 1336 1358 1336 1359 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1.3	1.9e+02	3.7	0.1	3	23	24	44	23	44	0.94
2	15	4.4	6.5e+02	2.1	4.2	1	23	878	901	878	901	0.81
3	15	0.0012	0.18	13.3	2.2	3	23	985	1006	983	1006	0.96
4	15	0.0083	1.2	10.6	0.1	2	23	1019	1040	1018	1040	0.97
5	15	1.6e-05	0.0023	19.2	3.1	2	23	1043	1064	1042	1064	0.97
6	15	0.007	1	10.9	0.7	1	23	1070	1092	1070	1092	0.95
7	15	2.5e-05	0.0038	18.5	4.5	2	23	1099	1120	1098	1121	0.95
8	15	0.34	50	5.6	3.7	5	23	1134	1152	1133	1152	0.97
9	15	2.3e-05	0.0034	18.7	1.5	3	23	1159	1180	1158	1180	0.97
10	15	0.01	1.5	10.3	0.3	2	23	1196	1216	1195	1216	0.97
11	15	6.8e-05	0.01	17.2	0.7	1	20	1222	1241	1222	1244	0.92
12	15	8.5e-05	0.013	16.9	2.7	1	23	1252	1274	1252	1274	0.99
13	15	0.0034	0.51	11.8	3.4	1	23	1280	1302	1280	1302	0.97
14	15	4.3e-06	0.00065	20.9	3.9	1	23	1308	1330	1308	1330	0.99
15	15	0.0015	0.22	13.0	6.3	1	23	1336	1358	1336	1359	0.96

Sequence Information

Coding Sequence: ATGCATAAACAAAATATCGCAGACACAATGGATGCAACGAGCAATGGAACATCAGGGAGTACAATGGCTTGTCCAGTGTGTACCCTTTACTTACGTGAGGGTATCAGCTTACAGAGACATTTGGACACTCATCCTAAAGAACAAGTCATTGAAGCTCTTATCAAAGCTAGTACTAATTCGTTACATTTACAACAAACTCAGTTGTCACCATCAGCGCCTCCAGCATCTCCAGCTATACAATCACCACAAAATACATCTCAAGTTACACAGAATACTCATGTATCGGCTCAATCTCCATATCCTATAGGACCTATTTTCGAATGTCCACCCATTGGCACTGTAATGCCACCCCAGTTTGCTTCGTTCAGTTATCAACAGTTTGTAAATAATGGCACTATGATGATACCACAATACGCGATGGGTCCACAAGCTAATCAGATGATGCAGATGCTTTATAATCCATATGGCATGTACCAGCAACAACAGATACCGACTGTTCAGATGATCTCACCAGTCACAACTATATCGAATACAGCAAGAATTAGGCCAGTGGTGACCATGGCTGGTGAAACAAGCGGTAGAACTGCCATTGCTGTGTCTGTAAATAATTCCGAGCCAAAACAAATTTTACCTGAAATTTTACCTGAGTCAGAGCAAGAGTCTAAACAAGTGTTACCAGATATCAATCTTCCAGTTTCTCCTCCATCGTTGAATGAGGATAATTCTATACAACAAAATGAAAATGGAACTAGTACAATTCAAATAGAGCATGTGGAAGAACCTCATGGTTCAAGCACTGATCATCAGcataatatacaaaatgaatATGATAGCATTCCAAAAACATTAGAAATCACTTGTAATGTTGTTGATACTAGTGATGATAAAGTTGAGAGTGTATTACCAGATATCGATGATGGAGAATCACAAGTTATCACTGCAGATGTTCAGTGTAAACCCATTCATTATGAATCTTCAGAGATGCAAGAATATGTGCAGAGATATAaagatgataatgatagtagtaaaattatCATGCCTGAGATATCCATGGTAAGTGAGAGTGAAACTGAAAAAACAACTAATGAAAAAGTTCCTCACAGAAAAGAGATAAATGAAAATCAAGGTACCTCATCTGAAATGCCTATAAGAGATACAATAAAAGAATCAGCTCAACCTCAAGTAGAACATTTAGAACACCTTTTAATCACTATTGTGGAATCTGAATTTAATAGTGAAACACAAAAAGAATCTGATGACAAAAAGAAAGATGAAGTTCTGGAACCAAAATCTTCCTCTGAAAGAGCAGAAAGTGTAATTCAAACTAGTAATCCTGTTGAACATGATAGCAGTTATAACCCTGACATAGAAATAAAGATGAATGAGAGTTCAGAAAATTATCTAGATAGTGAAGAAAATAAGAATTCTTGTCTTTTGTATCATTATAAAAACAGTTTATCTGCACCTGCATCACCAGCGGTACAAAAAAAGTATAGGACATATTCAGTTCGTTCAGACTTTGGATCAAATGAAACTCTTAATTCTTATCCAATTGGTTTTGATGCAAATACATTGCAAGATGAAGATGAAGAGGATGAAAAAAATGAAGCGGAAGATAATTTTGATGAGGCAGATATGGAGATAGAGGAAATACCTAGCCCACACACACCTTTTGTTAAATATGGAGAAAGTACAGATCATATTAGATCACATACTCCATTATCTGTAAGTAGCGGTATCTCTGTATTGAGAGTTAGAAAAGATCTCAGTAAACCATGCTCACCTGCATCAGTACATTCATTTTGTCATATGgatgctaatgatataagtcacGATGAAGAAAGTAATACAGCAATGGATGCATCTCCAGAAAAAGATCCTATTGATTGTTCTTCAATTGAACAAGATGTAAAAGCTGATCAATCAGAACTTTCTATATgtgaaaatgaaaagaaagtaATAGACACAGCATATCAGTCTGTAATTACTGAACATGTGAGTTCATTTCCTACAATTCATTCTCAACAATCAACATCGATAGATGAGTCATATAATGCAACAAACAAAAGTCATAATCTTGTAAATTTGTCAGAATCTAGTGATATTGCAAGTAGTTCTGATTCAAAAAGCTTTCACTCTAAATCAATTATACAAAAGCAATCGGTGGAACTTCTTAGTTTAAACGAGGATGCTCATGCAGGTCCAATGAATATGTTTGAATTAGATGGTCTTCAAATATTAGTTCCTAGTACATTTATAAGTGATTCTTCACAAAAAGCTGTTAGTGCAACCAGTCAACAGTCTATGGCGAGTAGTGAAGGAGGAATAGGTGTAGATGAAGAAGTGAAAAGTATTAACATGAGGGCTGATGAAACTATGCCACCTAGAGGTGAATTATCGGAACAAGAAAGCAATGGATGTACAGAGCAATCAGCTTGGCAGTTGTATGCTGGTCAAGAATCATCACGAATGTCAACCTCTTATGATTTGATGGCACGTGAAAGTTGGGAAGAATCAGAAGGATCAGACAATGAAATTAGTGGTCCGTTATTAGATAGCAGATCTTTAGCCACACATTTTACATCAAGTTTATTCTTAGATCGAGATAGAAAAACACCGACAAAAAGAACATTTAAATGTTATCATTGCCCAGAAACATTTGATTGTCCGAAAGAACGTCGAGTACACAGTACTACCGTGCATCAAGAAGCCGGACCCAGTAGCAGTAGAGAATCAACGGATCAGCCTGAAGTGAAGGATATTAAGTTGCTGGATGGTCGCATGAATGCATTTGACGATTTTTTTGTACCGGGTTTACACGTTCAACAAACTTACCATCAACAACCGCTTTTACATCAACTCCAACCACCGCAATCATCGGAATTAACAGCAAAAGTAGAACCTGATCAAAAAATCGAAACGTTGGTAATACCATCGAATATCGAGGTGATTTGTACACTTTGTAATCAAAGATTTAGTAGTGAAAAATCGTTACAATTACATCATAAAAGAGTACATGTTACAGAAACAGCGAAAAGAATTCGAGAGAGTACTAAGTGCCAGATATGTAACGAAGAATTTCCTTCGGTTTTACTGTTTAATGCCCACCTAAAAATACATCCGTTAGAATGTAGCCAATGTGGGAAGTATTTTTATaggaaacaaaattttaaattacatatgaaACGACATCTAGGAATCAAACCATTTCCGTGTACCGTTTGCGACAAAACATTTTTGACAAAACAAAAATTAGACGAGCATACCAATGGCCACACCGGGAATGCACCTGTCAAGTGTAATCTTTGCAATGAAACGTTTCGCAGATATTCGAATTTAACACAGCACAAAAACAGACATCACTTgaacataaaaaagaaattgaaggatTACATATGTCACTGTGGTGAAATTTTTCATACAAAGAAGAAATTAGCCTGGCATAAGGAAACACACGATGAAAAACCAAAAGCATGTACATACTGTAACGAAAGATTCATTCACATGGCTAGCCTGACTCGACACATGCGTCGAGCTCATAACAGAAGATTTGTTCCCGACGCTCAAAGGGAAAACGAAAACGTTGAATGTCCCAtatgtaagtgtatttatttgcGATCTTCCTTAGCAGTACATATGCGAGTTCACAATGGCGAAAGACCATACGAATGTCAAGTTTGCTCGAAGGCATTTAGTACTAAGTGGAATTTACAATTGCACAAATGGACTCACGCTGCTCGTAGCACCAAACCCTTTAAATGTAATCAGTGTAGTGCCGCGTTTTACCGGCACAGCGATTACACTGCTCACATGAATTCCCATAGAAATGTGCGTCCTTTTACCTGCAATTACTGCGGTGCGCAATTCATACGAAAGTATAATTGTTTAAGGCATGTGAAGGAACACGAAGAAAGCAAAGCGTATACATGCGATGTTTGCAACAAAACGTTTCATAGATCATATTATCTGAAAGAACACTTGCGAGTACATTCAGGTGCCAGACCATATACATGTCATATTTGTGGAAAGTCTAGCGGTACGAAATCCAATCACAACAAACATGTCAGAATTCATCATGCACGCGAACCTGTAAAtaccgaaaattaa
Protein Sequence: MHKQNIADTMDATSNGTSGSTMACPVCTLYLREGISLQRHLDTHPKEQVIEALIKASTNSLHLQQTQLSPSAPPASPAIQSPQNTSQVTQNTHVSAQSPYPIGPIFECPPIGTVMPPQFASFSYQQFVNNGTMMIPQYAMGPQANQMMQMLYNPYGMYQQQQIPTVQMISPVTTISNTARIRPVVTMAGETSGRTAIAVSVNNSEPKQILPEILPESEQESKQVLPDINLPVSPPSLNEDNSIQQNENGTSTIQIEHVEEPHGSSTDHQHNIQNEYDSIPKTLEITCNVVDTSDDKVESVLPDIDDGESQVITADVQCKPIHYESSEMQEYVQRYKDDNDSSKIIMPEISMVSESETEKTTNEKVPHRKEINENQGTSSEMPIRDTIKESAQPQVEHLEHLLITIVESEFNSETQKESDDKKKDEVLEPKSSSERAESVIQTSNPVEHDSSYNPDIEIKMNESSENYLDSEENKNSCLLYHYKNSLSAPASPAVQKKYRTYSVRSDFGSNETLNSYPIGFDANTLQDEDEEDEKNEAEDNFDEADMEIEEIPSPHTPFVKYGESTDHIRSHTPLSVSSGISVLRVRKDLSKPCSPASVHSFCHMDANDISHDEESNTAMDASPEKDPIDCSSIEQDVKADQSELSICENEKKVIDTAYQSVITEHVSSFPTIHSQQSTSIDESYNATNKSHNLVNLSESSDIASSSDSKSFHSKSIIQKQSVELLSLNEDAHAGPMNMFELDGLQILVPSTFISDSSQKAVSATSQQSMASSEGGIGVDEEVKSINMRADETMPPRGELSEQESNGCTEQSAWQLYAGQESSRMSTSYDLMARESWEESEGSDNEISGPLLDSRSLATHFTSSLFLDRDRKTPTKRTFKCYHCPETFDCPKERRVHSTTVHQEAGPSSSRESTDQPEVKDIKLLDGRMNAFDDFFVPGLHVQQTYHQQPLLHQLQPPQSSELTAKVEPDQKIETLVIPSNIEVICTLCNQRFSSEKSLQLHHKRVHVTETAKRIRESTKCQICNEEFPSVLLFNAHLKIHPLECSQCGKYFYRKQNFKLHMKRHLGIKPFPCTVCDKTFLTKQKLDEHTNGHTGNAPVKCNLCNETFRRYSNLTQHKNRHHLNIKKKLKDYICHCGEIFHTKKKLAWHKETHDEKPKACTYCNERFIHMASLTRHMRRAHNRRFVPDAQRENENVECPICKCIYLRSSLAVHMRVHNGERPYECQVCSKAFSTKWNLQLHKWTHAARSTKPFKCNQCSAAFYRHSDYTAHMNSHRNVRPFTCNYCGAQFIRKYNCLRHVKEHEESKAYTCDVCNKTFHRSYYLKEHLRVHSGARPYTCHICGKSSGTKSNHNKHVRIHHAREPVNTEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00962003;
90% Identity: iTF_01122626;
80% Identity: -