Basic Information

Insect: Megachile leachella
Gene Symbol: -
Assembly: GCA_963576845.1
Location: OY756251.1:17212491-17221219[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.00038 0.056 14.8 0.7 2 19 449 466 448 470 0.89

2 17 3.5e-05 0.0053 18.1 4.2 1 23 476 498 476 498 0.98

3 17 0.001 0.16 13.4 0.1 3 23 506 527 504 527 0.93

4 17 1.1 1.6e+02 4.0 1.2 1 23 534 557 534 557 0.97

5 17 9.3e-05 0.014 16.7 0.7 1 23 561 583 561 583 0.97

6 17 0.0023 0.35 12.3 0.5 1 23 589 611 589 611 0.98

7 17 0.00018 0.027 15.8 2.3 1 23 617 639 617 639 0.96

8 17 6e-06 0.0009 20.5 2.7 1 23 644 666 644 666 0.96

9 17 0.057 8.5 8.0 0.5 1 23 1239 1262 1239 1262 0.98

10 17 0.00011 0.016 16.5 0.4 1 23 1268 1290 1268 1290 0.98

11 17 0.019 2.8 9.5 3.2 1 23 1296 1318 1296 1318 0.98

12 17 2.7e-05 0.0041 18.4 0.3 3 23 1326 1346 1324 1346 0.97

13 17 0.059 8.8 7.9 1.7 3 23 1353 1374 1351 1374 0.95

14 17 8.6e-05 0.013 16.9 2.0 1 23 1378 1400 1378 1400 0.98

15 17 0.029 4.4 8.9 0.6 1 23 1405 1427 1405 1427 0.98

16 17 6e-07 9e-05 23.6 0.3 1 23 1433 1455 1433 1455 0.98

17 17 0.00023 0.035 15.5 1.6 1 21 1460 1480 1460 1481 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.00038	0.056	14.8	0.7	2	19	449	466	448	470	0.89
2	17	3.5e-05	0.0053	18.1	4.2	1	23	476	498	476	498	0.98
3	17	0.001	0.16	13.4	0.1	3	23	506	527	504	527	0.93
4	17	1.1	1.6e+02	4.0	1.2	1	23	534	557	534	557	0.97
5	17	9.3e-05	0.014	16.7	0.7	1	23	561	583	561	583	0.97
6	17	0.0023	0.35	12.3	0.5	1	23	589	611	589	611	0.98
7	17	0.00018	0.027	15.8	2.3	1	23	617	639	617	639	0.96
8	17	6e-06	0.0009	20.5	2.7	1	23	644	666	644	666	0.96
9	17	0.057	8.5	8.0	0.5	1	23	1239	1262	1239	1262	0.98
10	17	0.00011	0.016	16.5	0.4	1	23	1268	1290	1268	1290	0.98
11	17	0.019	2.8	9.5	3.2	1	23	1296	1318	1296	1318	0.98
12	17	2.7e-05	0.0041	18.4	0.3	3	23	1326	1346	1324	1346	0.97
13	17	0.059	8.8	7.9	1.7	3	23	1353	1374	1351	1374	0.95
14	17	8.6e-05	0.013	16.9	2.0	1	23	1378	1400	1378	1400	0.98
15	17	0.029	4.4	8.9	0.6	1	23	1405	1427	1405	1427	0.98
16	17	6e-07	9e-05	23.6	0.3	1	23	1433	1455	1433	1455	0.98
17	17	0.00023	0.035	15.5	1.6	1	21	1460	1480	1460	1481	0.94

Sequence Information

Coding Sequence: ATGGAGTTAGGGGAGGGAGAGGCGAAGATTTGTCGTCTTTGCGGCCAGTGCGAAAGTATATATATTGATGTGTTCGGTGAAGAAGGTACCAAACGATTTTTGGGATTGAAGATTTATACGAAAATCAACATTTTGATAGATGAGAGGGATCCTCTGCCCAAGGCGATCTGTGTTCAGTGTCTGGGCAAGCTCGAATTCGTTTGTGACTTCCAAGAGGAGTGTCTTCGCACCCAACAAGTGTTACGCGATCGATACAGTCTACCACCCTTGTCAGAAATTGTTGATGTAAAGACTGAAGTTACAACACCAAGCACTTCAACAAATAATAACAATGACattgataaaaatttaaattctccAAGTGAGAAGACTGTCAGAGAAGTGGAACGTGCTTCAAAGACAGCTACAAAAACTCCAAGAAATTTAAGGAGTCAGCAGCCAGTGAAAAATACGGATGAATCTACAAAAGAACAAAATAATGAACAAAACCAGAGTGAGAATGCTACAAAAGAGGTAGAAACTGTTGAAAGCTCAGAAACACCTACACGTTGGCTTAGAAGCAGACAAAGCACAGAAGCAACTATCACCAATGAAACAACAAGTGATATGCCAATTGCAAACAGACTTAGAAGTCATAACAATACTGCCACAGAAGTAACTGTTAACAGTTCACGCAACAGCTCAACTACAAATCTTGAAAAGCAAATTGGAAAGCAAGATTCCCATactatccaaattccaacatccgcATTAAACAAACTTCTCACCATTGTCTCAAACTCTCCGAACATTGAGGTTTCCGTGAAAGAATCCAGGAATCAAAACAGTGATATTGAAGATATTAGTTTCACTGTAGAACTATGTAAAAAGGAAAGCGACGATGTTGCCACAGTTCGAGCACGGGTATTTCCAGATCAAGGTTCATGCCTAGTAGATAAAGCTATTGTTGGTCTTCTACAGAGCCAAAGTTGCGTAGaagtaaatagtataataaataccattatcagcagtagtCTTAAGAATGGTAATTCGACTAAGTCGAAAGACTCTGCGGAATTCGAGCAGAAATGGCAGGCTTCTCAAAATCCTGAAGAATTGTTCAAGATCGACGGAGAAGAGATTCGTGTGGATGACAATGTCGAACATGTTGTATCGGACAATCAAAACGGCTATTCCTGTAAATTGTGTTGCAAGTTTTATGAACGTAAAGATAAGTGTATGGTTCACGTGAAGACTCACCTCGGAATTAAACAGTATACCTGTATTTTATGTAACGCTAAATTCGTATGTAAGTCCGACGTTATGAAACATATCCGATGTTCGCATACTAATCCAAGGCCAATACAATGCCCAAAGTGCCCAAAACGATTCAAATCGAAATTCTATTTGATGGAACACGATAATGTACACAAAGGCGTGAGGCCTTACTCTTGTACGGACTGCGGTCAAAGTTATCACCATAAAGTGTCGTTACAGATCCACATGAAATCGCATTTACCTCCGCAGAATTTAGCTTGCGAATATTGTGGCAAAGTGTTTCCTTATCGTACGAGATTGCTGAGTCATGTTGCTAGTGTACACTTGAAAAACCGTCGCAACTTTAGGTGTCGATTTTGCTATAATCTTTATTCGAGTCTCGCGGTTTTAaacgaacacattaaaacgcgACATGCAACAACTTATACATGTGAGGTTTGTAGTAAAACGTTCAAGGTAGCGTCCAAGTATAAAGCTCACGTGTTGCAACACTCTAATCCTAAGCCCTTCGTGTGTAACGTCTGTAACAATAGATACGCATCCAAAGCATTCCTGAACGAACACTTATTGAAACACGAAGGGTTGAGGAAACACATATGCCAGAAATGTGGTGCGAGATTCGCTCAAGCTAGTCATCTGGCTGCGCACCGGCACGTGCACGGTGAAAAGATGCACGCTTGTCCAGAGTGCGGGCGTAAGTTTAATAGACGCGATAACATGAAAGTACATAGAAAAAGACATTTCGAAGATAAAAAGACTGGTATTATTAAACAAAAGAATGCTTCTAACGTTGACATAAAAAAGAACGATGGATTGCCTCAAATTGTGTGCATGCGATGTCTGGGCACGTTGGAATTCTTGTGTGACTTCTACGACAGCTGCCATCATGCTCAAAAGGAACTCTCAGAGGTTGTAAGTTATAATTTAACATATTGCCTTTATTCACAGAATCATGTATTAATGATTCTTATTCCACAGGTTCAAAAGGAAAATGACGCTGAATCGGACAAAGAAAATGCTGCACCAACAATTGATAGTAAACGCAAAACCTTATTGCCAGTCACTAATAATTGTATAACCAAAAGTAATGTGTCATATAGCAATATTGAGAAAACGAATAACGTTCAGACTAAAACGAATGCATTAGATAATATAGTGAACACTCAGTCCACATTGGATAATATTCCTACACAAGAAAAGTGTTCAATGAACAGACAGAGTGATGGCACGAAACTTAAACGCAAAACAAATTTCACAAGAAAGAACGCTATTATGAAGAAGACGAGTTCAAGAAATTTATTGAGAGAAGATGAAACAAATGTTAACGAAAACTCGGTGTTTCCTGTACGACGCAAGAGAGGCAGAAAGAGTAAATTGGAAAAAATGAGGGAGGCTGCGTTGTTACAGAAAGAGCTGCAGGATCTCATTGATAAAAGGAACAATGATTCTGATAACAAGAGCAAAAGATATTGTTTACGTAATATTTATGACAATACTAATTTCAatgatgtaattaaaaatactatAGTTCTGCCTAAACAAGTGGATGAAGTCACAGCGAAGGAACAGGTAGCAATGGACTCATCATTATTAAATGAGACTCATACGAAGGATAATACTACTAACATTGTGCGTAGTAACAAATCAACAAAAGCAAAACCTGAtgatgaaaacttgaagaatgtTGAAGACAGtccaaagaaaattgaaaacaattTGGTAAAAAATAAAGCAATATCTGTTATTGTGAAGCAAGAGAAATTGGAATCTGAAGCTACACTTTCTAAACAGACTGAGAAGTTGAATCAGTTAACTTGGATTCCTAATGAGATTTTGGTGCAAGAAAACATAAATTTGACTGATAACGAGAATGAGAATCAGACGGGTCAACAATCAAATTCTCCACTAACAGCAGAAGTCACTAATAccgaaacaagtaaaagtactGTAAACACAGAATCCAATGTTACTGATTACTCCAACTTACCTAATGATCAAAGTAGTTTGAAACCAAGAGCACTCACGGAACAAAATCGCGTGACTGTTATAAAATCGGCAAACGAGACAGCTACTGCAACAATTGAGAAAGATCCTTTAGAACTGTGCATTAAAGCAGATACATTGAATCAAAATGTTGAGGGAGATTTAAAGTCTAGTCTAACTGAACAATTGTTGCTGCAACAAAACAATCAAAGtaacagttctgacgatagtaaggAACAGAGGAAGAGCAAAGACAAGTTGTTCTTTAAAATCTCTGAATTGATTAGTGATGAAGAAAAACAAGCCATTGAAACTTATTACACGGTTGACATGTCGATTGTCGATCATGAAGAGGTACAGAAGAATTTAACGATAGTCGATAAAAAGAATATACGTTGCAATATTTGTGGACTCTTTTACCTCAGAATAGATAAGTGTCAAGTACACGTTTGGGGCCATTTGCAAATGAAACCTTACCAATGCAAAGCGTGTGATTTTTCTACTGTAACTGTTACCAATATTCGTGGACATATTAGAAAAagtcatttaaaattgaagCCATTTCCGTGCCATATTTGTGAGAAACGGTATGCCACTGCGTTTCTTTTAGATGAACATATGAATGTTCATACAGGTGACCGTccatataaatgtaaattatgTGATTTTTCGACTTCAAGAAGACAAATGCTGAGTTATCATAATTCGACTCATAAAGTATTAAAGGATGTCAATTGTAAGGTTTGTGGAAAAGAGTTTTATTCAAGAGGCAGGTTACGAGCACACATGATCATGCACAACAAGGATAAAGTTATATGTAAATTGTGTTCTGCTTGCTTATCCAATCAAGAAGCTTTAGAAACACATCATAAAAATGTGCATATGCAAGATTACATATGCAGTATTTGTGGTAAACGCCTTAAGTCAAAGAAGGCTTTGCATAACCATAGAAATgTACATGCTGTTGGAAAGTATAAATGTTCCTTGTGTCCTAATGTGTACAAAAGTagtcaaatattaaaagaacatCTTTTGAAACACAAAGGTATTAGGAATTATAAGTGCAACGTCTGTGAAAAAGCATTTGGACAACAGTCTCATTTAGCTGCTCACATGGCAGTACATAGTAAAATTAGATTTCATTGCCCTGGATGTGACAGACCTTTCAATCGGCATGATAACATGAAAATACATACTAAACGATGCAAAGTGTTTCTGGCGAATCCAGAACTTAAAAACTTTTTTACAAAAAGAGAAAGATGTTCGTCGTTTACTAAAGTCACAGAAGTAGAAGATGACCTGAGAAGCGATGATATATCAACACCCACTTCGCCTATGTTTGTTGAGAGTCAAACTAGTGAATTGTCAACGGAAAATATAGATAATCAAGATAAGGCTGCAGTAAATTTCTGCAAGTTAGGATTGAACATCTCTTGTATCGAGCCAGTAAATAAAACTTGGGATCACAATTTATATGAGAAAACAGAAGTTACAAGGTCCACTGAAATTAATGTGATTCAAATTACACAAGTTAATGATAAATTCATTCCAGAAAGCGAAAATCTAACGGTTCTTGAAAACGTTTTGAGACCAGAAAGTTTTTGA
Protein Sequence: MELGEGEAKICRLCGQCESIYIDVFGEEGTKRFLGLKIYTKINILIDERDPLPKAICVQCLGKLEFVCDFQEECLRTQQVLRDRYSLPPLSEIVDVKTEVTTPSTSTNNNNDIDKNLNSPSEKTVREVERASKTATKTPRNLRSQQPVKNTDESTKEQNNEQNQSENATKEVETVESSETPTRWLRSRQSTEATITNETTSDMPIANRLRSHNNTATEVTVNSSRNSSTTNLEKQIGKQDSHTIQIPTSALNKLLTIVSNSPNIEVSVKESRNQNSDIEDISFTVELCKKESDDVATVRARVFPDQGSCLVDKAIVGLLQSQSCVEVNSIINTIISSSLKNGNSTKSKDSAEFEQKWQASQNPEELFKIDGEEIRVDDNVEHVVSDNQNGYSCKLCCKFYERKDKCMVHVKTHLGIKQYTCILCNAKFVCKSDVMKHIRCSHTNPRPIQCPKCPKRFKSKFYLMEHDNVHKGVRPYSCTDCGQSYHHKVSLQIHMKSHLPPQNLACEYCGKVFPYRTRLLSHVASVHLKNRRNFRCRFCYNLYSSLAVLNEHIKTRHATTYTCEVCSKTFKVASKYKAHVLQHSNPKPFVCNVCNNRYASKAFLNEHLLKHEGLRKHICQKCGARFAQASHLAAHRHVHGEKMHACPECGRKFNRRDNMKVHRKRHFEDKKTGIIKQKNASNVDIKKNDGLPQIVCMRCLGTLEFLCDFYDSCHHAQKELSEVVSYNLTYCLYSQNHVLMILIPQVQKENDAESDKENAAPTIDSKRKTLLPVTNNCITKSNVSYSNIEKTNNVQTKTNALDNIVNTQSTLDNIPTQEKCSMNRQSDGTKLKRKTNFTRKNAIMKKTSSRNLLREDETNVNENSVFPVRRKRGRKSKLEKMREAALLQKELQDLIDKRNNDSDNKSKRYCLRNIYDNTNFNDVIKNTIVLPKQVDEVTAKEQVAMDSSLLNETHTKDNTTNIVRSNKSTKAKPDDENLKNVEDSPKKIENNLVKNKAISVIVKQEKLESEATLSKQTEKLNQLTWIPNEILVQENINLTDNENENQTGQQSNSPLTAEVTNTETSKSTVNTESNVTDYSNLPNDQSSLKPRALTEQNRVTVIKSANETATATIEKDPLELCIKADTLNQNVEGDLKSSLTEQLLLQQNNQSNSSDDSKEQRKSKDKLFFKISELISDEEKQAIETYYTVDMSIVDHEEVQKNLTIVDKKNIRCNICGLFYLRIDKCQVHVWGHLQMKPYQCKACDFSTVTVTNIRGHIRKSHLKLKPFPCHICEKRYATAFLLDEHMNVHTGDRPYKCKLCDFSTSRRQMLSYHNSTHKVLKDVNCKVCGKEFYSRGRLRAHMIMHNKDKVICKLCSACLSNQEALETHHKNVHMQDYICSICGKRLKSKKALHNHRNVHAVGKYKCSLCPNVYKSSQILKEHLLKHKGIRNYKCNVCEKAFGQQSHLAAHMAVHSKIRFHCPGCDRPFNRHDNMKIHTKRCKVFLANPELKNFFTKRERCSSFTKVTEVEDDLRSDDISTPTSPMFVESQTSELSTENIDNQDKAAVNFCKLGLNISCIEPVNKTWDHNLYEKTEVTRSTEINVIQITQVNDKFIPESENLTVLENVLRPESF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00961983; iTF_00964629;
90% Identity: iTF_00964629; iTF_00961983;
80% Identity: -