Basic Information

Insect: Megachile lagopoda
Gene Symbol: -
Assembly: GCA_036983795.1
Location: CM072787.1:6400818-6409826[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.00037 0.043 14.8 0.7 2 19 449 466 448 470 0.89

2 17 3.5e-05 0.004 18.1 4.2 1 23 476 498 476 498 0.98

3 17 0.001 0.12 13.4 0.1 3 23 506 527 504 527 0.93

4 17 1 1.2e+02 4.0 1.2 1 23 534 557 534 557 0.97

5 17 9.2e-05 0.011 16.8 0.7 1 23 561 583 561 583 0.97

6 17 0.0023 0.27 12.3 0.5 1 23 589 611 589 611 0.98

7 17 0.00018 0.021 15.8 2.3 1 23 617 639 617 639 0.96

8 17 5.9e-06 0.00069 20.5 2.7 1 23 644 666 644 666 0.96

9 17 0.056 6.5 8.0 0.5 1 23 1230 1253 1230 1253 0.98

10 17 0.00011 0.012 16.6 0.4 1 23 1259 1281 1259 1281 0.98

11 17 0.018 2.1 9.5 3.2 1 23 1287 1309 1287 1309 0.98

12 17 2.7e-05 0.0031 18.4 0.3 3 23 1317 1337 1315 1337 0.97

13 17 0.058 6.8 7.9 1.7 3 23 1344 1365 1342 1365 0.95

14 17 8.4e-05 0.0098 16.9 2.0 1 23 1369 1391 1369 1391 0.98

15 17 0.029 3.3 8.9 0.6 1 23 1396 1418 1396 1418 0.98

16 17 5.9e-07 6.9e-05 23.6 0.3 1 23 1424 1446 1424 1446 0.98

17 17 0.00023 0.026 15.5 1.6 1 21 1451 1471 1451 1472 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.00037	0.043	14.8	0.7	2	19	449	466	448	470	0.89
2	17	3.5e-05	0.004	18.1	4.2	1	23	476	498	476	498	0.98
3	17	0.001	0.12	13.4	0.1	3	23	506	527	504	527	0.93
4	17	1	1.2e+02	4.0	1.2	1	23	534	557	534	557	0.97
5	17	9.2e-05	0.011	16.8	0.7	1	23	561	583	561	583	0.97
6	17	0.0023	0.27	12.3	0.5	1	23	589	611	589	611	0.98
7	17	0.00018	0.021	15.8	2.3	1	23	617	639	617	639	0.96
8	17	5.9e-06	0.00069	20.5	2.7	1	23	644	666	644	666	0.96
9	17	0.056	6.5	8.0	0.5	1	23	1230	1253	1230	1253	0.98
10	17	0.00011	0.012	16.6	0.4	1	23	1259	1281	1259	1281	0.98
11	17	0.018	2.1	9.5	3.2	1	23	1287	1309	1287	1309	0.98
12	17	2.7e-05	0.0031	18.4	0.3	3	23	1317	1337	1315	1337	0.97
13	17	0.058	6.8	7.9	1.7	3	23	1344	1365	1342	1365	0.95
14	17	8.4e-05	0.0098	16.9	2.0	1	23	1369	1391	1369	1391	0.98
15	17	0.029	3.3	8.9	0.6	1	23	1396	1418	1396	1418	0.98
16	17	5.9e-07	6.9e-05	23.6	0.3	1	23	1424	1446	1424	1446	0.98
17	17	0.00023	0.026	15.5	1.6	1	21	1451	1471	1451	1472	0.94

Sequence Information

Coding Sequence: ATGGAGTTAGGGGAGGGAGAGGCGAAGATTTGTCGTCTTTGCGGCCAGTGCGAAAGTATATATATTGATGTGTTCGGTGAAGAAGGCACCAAACGATTTTTGGGATTGAAGATTTATACGAAAATCAACATTTTGATAGATGAGAGGGATCCTCTGCCCAAGGCGATCTGTGTTCAGTGTCTGGGCAAGCTCGAATTCGTTTGTGACTTCCAAGAGGAGTGTCTTCGCACCCAACAAGTGTTACGCGATCGATACAATCTACCACCCTTATCAGAAATTGCTGATGTAAAGACTGAAGATACAACACCAAGCACttcaacaaataataacaacaatgatattgataaaaatttaaattctccaaGTGAGAAGACTGTCAAAGAAGTAGAGCGTGTTTCAAAGACAGCTACAAAAACtcaaagaaatttgagaagtcaGCAGCAAGTGAAAAGTAACGAGGAACCTACAAAAGATCAAAATAATGATCAAAACCAGAATGAGAATGCTACAGAAGATGTACAGACTATTGAAAGCTCAGAAACAACTACACGTTGGCTTAGAAGCAGACAAAGTACAGAAGCAACTACCACGAATGAAACAACAAGTGATATGCCAATCGCGAACAGACTTAGAAGTCATAACAATACTGCCACAGAAGTAACTGTTAATTCACGCAACAGCTCAaatgcaaatattgaaaagcAAATTGGAAAACAAGATTCTCATActatccaaattccaacatctgCATTAAATAAACTTCTCACTATTGTATCAAACTCTCCAAACATTGAGGTTTCCGTGAAAGAATCCAGGAATCAAAACAGTGATATCGAAGATATTAGTTTCACTGTAGAATTATGTAAAAAGGAAAGCGACGACGTTGCCACAGTTCGAGCACGAGTATTTCCAGACCAAGGTTCATGCCTAGTAGATAAAGCTATTGTTGGTCTTCTACAGAGCCAAAGTTGCGTAGAagtaaatagtataataaataccATTATCAGCAGTAGTCTTAAGAATGGTAATTCGACAAAATCGAAAGACTCTGCGGAATTCGAGCAAAAATGGCAGGCTTCTCAAAATCCTGAAGAATTGTTCAAGATCGACGGAGAAGAGATTCGTGTGGATGACAACGTCGAACATGTTGTATCGGACAATCAAAACGGCTATTCCTGTAAATTGTGTTGCAAGTTTTATGAACGTAAAGATAAGTGTATGGTTCACGTGAAGACTCATCTCGGGATTAAACAGTATACCTGTATTTTATGTAACGCTAAATTCGTATGTAAGTCCGACGTCATGAAACATATTCGATGTTCGCATACTAATCCAAGGCCAATACAATGCCCAAAGTGCCCAAAACGATTCAAATCGAAATTCTATTTGATGGAACACGATAACGTACACAAAGGCGTGAGACCTTACTCTTGTACGGACTGCGGTCAAAGTTATCACCATAAAGTGTCGTTACAGATCCACATGAAATCGCATTTACCTCCGCAGAATTTAGCTTGCGAATATTGTGGCAAAGTGTTTCCTTATCGTACGAGACTACTGAGTCACGTTGCTAGTGTACACTTGAAAAACCGTCGCAACTTTAGGTGTCGATTTTGCTATAATCTTTATTCGAGTCTCGCGGTTTTAAACGAACATATTAAAACACGACACGCAACAACGTATACATGTGAGGTTTGTAGTAAAACGTTCAAGGTCGCGTCCAAGTATAAAGCTCACGTGTTGCAACACTCTAATCCTAAGCCCTTCGTGTGTAACGTCTGTAACAATAGATACGCGTCCAAAGCATTCCTGAACGAACACTTATTGAAACACGAAGGGTTGAGGAAACACATATGCCAGAAATGTGGTGCGAGATTCGCTCAAGCTAGTCATCTGGCTGCGCACCGGCACGTGCACGGTGAAAAGATGCACGCCTGTCCAGAGTGCGGGCGTAAGTTTAATAGACGCGATAACATGAAAGTACATAGAAAAAGACATTTCGAAGATAAAAAGACTggtattattaaacaaaagaatGCTTCTAATGTTGACATAAAAAAGAACGATGGATTGCCGCAAATTGTGTGCATGCGATGTCTGGGCACGTTGGAATTCTTGTGCGACTTCTACGACAGCTGCCATCACGCTCAAAAGGAATTCTCGGAGGTTGTTCAAAAGGAAACTGAAGATGAACTCCAACGAGAAAATGACGCTGAATCGGACAAAGAAAATGCTGCCCCACCAACAATTGATACGAAACGCAAAACGAAAGCTTTATCGCCAGTCACTAATAACTGTATAACCAAAAGTAACGTGCCGTATAGCAATATCGAGAAAACGAATAACATTCAGACTAATACGAATGCATTAGAAAATATAGTTTCGAACACTTCATCTACGATAGATAATATTCCTGCGCGAGAAAAGTATTCAATGAACAGAGAAAATAATGGTACGAGACTTAAACGCAAAACAAATTTCGCATCAAGAAGGGACGCTATTATGAAGAAGACAAGTTCAAGAAATTTATTGCGAAAAGATGAAACAAATGTTAACGAAAACTCGGTGTTTCCTGTACGACGCAAGAGAGGCAGAAAgagtaaattggaaaaaatgcGGGAGGCTGCATTGTTACAGAAAGAGCTGCAGAATGTCATTGATAAAAGGAACAATGATTCTGATAACAAGTGCAAAAGATATTgtttacgaaatatttatgacaatACTAATTTCAATGATGTAATTAAAAGTACTATAGTTCTACCTAAGCCGCAAGTGGATGAAACCACAACGAAGGAACAGATAGCAATGGACTCATCATCAAATGAAACTCATATGAAGGATAATACTACTAATATTGTGCATAGTAATAAaccaacaaaaacaaaacctgatgatgaaaacttgaagaatgtTGAAGATTGTtcaaggaaaattgaaaacaatttgGTAAAGAATAAAGCAATATCTGTTATTGTGAAGCAGGAGAAACTAGAATCTGAAGGTACACTTACTAAACAGAGTGAGAAATTGAATCAGTTAACTTGGATTCCTAATGAGATTTTGATGcaagaaaacataaatttgtCGGATAACGAGAATGAGAATCAAACGGGCCAACAATTAAGTTCACCATTAAGAACAGAAATCACTAATACtgaaaaaagtaaaagtacTGCGACCATAGAATCCAATGTTACTAATTGCTCCAACCTATCTAATGATCAAAGTAGTTTGAAACCAATAGCATTCACGGAACAAAATCGCGTAACTGTTATAAAGTCGTCAAACGAGACAGCCACTGCAACGATTGAGAAAGATCCTTTAGAACTGTGCATTAAAGCAGATACATTGAATCAAAGTGTAGAGGGTGATTTAAAGTCTAGTCTAACTGAACAATTGTTGTTGCAACAAAACAATCAAAGTAACAGTTCTGATGAAAGCAGGGAACAAAGGAAGAGCAAAGACAAGTTGTTCTTTAAAATCTCTGAATTGATTAGTGATGAAGAAAAACAAGCCATTGAAACGTATTATACGGTCGACATGTCGATTGTCGATCATGAAGAAGTACAGAAGAATTTAACGATAGtcgataaaaagaatatacgtTGCAATATTTGTGGACTCTTTTACCTCAGAATAGATAAGTGTCAAGTACATGTTTGGGGCCATTTGCAAATGAAACCTTACCAATGCAAAGCGTGTGATTTTTCTACCGTAACTGTTACCAATATTCGTGGTCATATTAGAAAAagtcatttaaaattgaagccATTTCCGTGCCATATCTGTGAGAAACGGTATGCCACTGCGTTTCTTCTAGATGAACATATGAATGTTCATACGGGTGACCGTccatataaatgtaaattatgtgATTTTTCGACTTCAAGAAGACAGATGCTGAGTTATCATAATTCGACTCATAAAGTATTAAAGGACGTCAATTGTAAGGTTTGTGGAAAAGAGTTCTATTCAAGAGGCAGATTACGAGCACACATGATCATGCATAACAAGGATAAAGTTATATGTAAATTGTGTTCTGCTTGTTTATCCAACCAAGAAGCTTTAGAGACACATCATAAAAATGTGCACATGCAAGATTACATATGCAGTATTTGTGGTAAACGCCTTAAATCAAAGAAGGCTTTGCATAACCATCGAAATGTACATGCTGTTGGAAAGTACAAATGTTCCTTGTGTCCGAATGTGTACAAAAGTagtcaaatattaaaagaacatCTTTTAAAACACAAAGGTATTAGGAATTACAAGTGCAACGTCTGTGAAAAAGCATTTGGACAACAATCTCACTTAGCTGCTCATATGGCAGTACATAGTAAAATTAGatttcattGCCCTGGATGTGATAGACCTTTCAATCGGCATgacaatatgaaaatacataCTAAACGATGCAAAGTGTTTCTGGCGAATCCAGaacttaaaaacttttttataaaaagagaaagatgTTCATCGTTTACTAAGGTCACAGAATTAGAGGATGATCTGAGAAGCGAAGATATATCAACACCCACTTCACCTACGTTTGTTGAGAATCAAAATAGTGAATTGTCAACAGAAACTGTAGATAATCAAAATAAGACTGCAGTCAATTTCTGCAAATTAGGACTGAACATCTCTTGTATCGAGCCAGTAAATAAAACTTGGGATcacaatttatatgaaaaagcAGAAGTCACAAGATCCCctgaaattaatgtaattcaaATTACGCAAGTTAATGATAAATTCATTCCAGAAAGCGAAAATCTAACAGTTCTTGAAAACGTTTTGAGACCAGAAAGTTTTTGA
Protein Sequence: MELGEGEAKICRLCGQCESIYIDVFGEEGTKRFLGLKIYTKINILIDERDPLPKAICVQCLGKLEFVCDFQEECLRTQQVLRDRYNLPPLSEIADVKTEDTTPSTSTNNNNNDIDKNLNSPSEKTVKEVERVSKTATKTQRNLRSQQQVKSNEEPTKDQNNDQNQNENATEDVQTIESSETTTRWLRSRQSTEATTTNETTSDMPIANRLRSHNNTATEVTVNSRNSSNANIEKQIGKQDSHTIQIPTSALNKLLTIVSNSPNIEVSVKESRNQNSDIEDISFTVELCKKESDDVATVRARVFPDQGSCLVDKAIVGLLQSQSCVEVNSIINTIISSSLKNGNSTKSKDSAEFEQKWQASQNPEELFKIDGEEIRVDDNVEHVVSDNQNGYSCKLCCKFYERKDKCMVHVKTHLGIKQYTCILCNAKFVCKSDVMKHIRCSHTNPRPIQCPKCPKRFKSKFYLMEHDNVHKGVRPYSCTDCGQSYHHKVSLQIHMKSHLPPQNLACEYCGKVFPYRTRLLSHVASVHLKNRRNFRCRFCYNLYSSLAVLNEHIKTRHATTYTCEVCSKTFKVASKYKAHVLQHSNPKPFVCNVCNNRYASKAFLNEHLLKHEGLRKHICQKCGARFAQASHLAAHRHVHGEKMHACPECGRKFNRRDNMKVHRKRHFEDKKTGIIKQKNASNVDIKKNDGLPQIVCMRCLGTLEFLCDFYDSCHHAQKEFSEVVQKETEDELQRENDAESDKENAAPPTIDTKRKTKALSPVTNNCITKSNVPYSNIEKTNNIQTNTNALENIVSNTSSTIDNIPAREKYSMNRENNGTRLKRKTNFASRRDAIMKKTSSRNLLRKDETNVNENSVFPVRRKRGRKSKLEKMREAALLQKELQNVIDKRNNDSDNKCKRYCLRNIYDNTNFNDVIKSTIVLPKPQVDETTTKEQIAMDSSSNETHMKDNTTNIVHSNKPTKTKPDDENLKNVEDCSRKIENNLVKNKAISVIVKQEKLESEGTLTKQSEKLNQLTWIPNEILMQENINLSDNENENQTGQQLSSPLRTEITNTEKSKSTATIESNVTNCSNLSNDQSSLKPIAFTEQNRVTVIKSSNETATATIEKDPLELCIKADTLNQSVEGDLKSSLTEQLLLQQNNQSNSSDESREQRKSKDKLFFKISELISDEEKQAIETYYTVDMSIVDHEEVQKNLTIVDKKNIRCNICGLFYLRIDKCQVHVWGHLQMKPYQCKACDFSTVTVTNIRGHIRKSHLKLKPFPCHICEKRYATAFLLDEHMNVHTGDRPYKCKLCDFSTSRRQMLSYHNSTHKVLKDVNCKVCGKEFYSRGRLRAHMIMHNKDKVICKLCSACLSNQEALETHHKNVHMQDYICSICGKRLKSKKALHNHRNVHAVGKYKCSLCPNVYKSSQILKEHLLKHKGIRNYKCNVCEKAFGQQSHLAAHMAVHSKIRFHCPGCDRPFNRHDNMKIHTKRCKVFLANPELKNFFIKRERCSSFTKVTELEDDLRSEDISTPTSPTFVENQNSELSTETVDNQNKTAVNFCKLGLNISCIEPVNKTWDHNLYEKAEVTRSPEINVIQITQVNDKFIPESENLTVLENVLRPESF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00962666;
90% Identity: iTF_00962666;
80% Identity: -