Basic Information

Insect: Megachile leachella
Gene Symbol: -
Assembly: GCA_963576845.1
Location: OY756250.1:786342-790799[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.017 2.5 9.7 2.4 1 23 377 399 377 399 0.95

2 18 0.00083 0.12 13.8 0.9 2 23 440 461 439 461 0.98

3 18 0.0041 0.61 11.6 2.2 1 23 572 594 572 594 0.93

4 18 0.0049 0.73 11.3 0.4 2 23 598 619 597 619 0.96

5 18 0.037 5.6 8.6 5.8 1 23 689 711 689 712 0.95

6 18 0.00041 0.061 14.7 0.6 1 21 718 738 718 742 0.92

7 18 0.026 3.9 9.0 5.0 2 23 823 844 822 844 0.95

8 18 0.00024 0.036 15.4 4.2 1 23 898 920 898 920 0.96

9 18 0.00031 0.046 15.1 0.7 1 20 925 944 925 946 0.94

10 18 0.046 6.8 8.3 0.5 2 23 957 978 957 978 0.97

11 18 1.4e-05 0.0021 19.3 0.7 2 23 1017 1038 1016 1038 0.97

12 18 2.8e-05 0.0042 18.4 1.6 1 23 1043 1065 1043 1065 0.95

13 18 0.00016 0.024 16.0 2.9 1 23 1071 1093 1071 1093 0.98

14 18 5e-06 0.00075 20.7 0.4 1 23 1109 1131 1109 1131 0.95

15 18 4.1e-07 6.1e-05 24.2 0.6 1 23 1137 1159 1137 1159 0.99

16 18 4.4e-05 0.0066 17.8 0.2 1 23 1165 1187 1165 1187 0.97

17 18 0.00016 0.024 16.0 4.1 1 23 1193 1215 1193 1215 0.96

18 18 0.012 1.7 10.2 0.4 1 20 1221 1240 1221 1242 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.017	2.5	9.7	2.4	1	23	377	399	377	399	0.95
2	18	0.00083	0.12	13.8	0.9	2	23	440	461	439	461	0.98
3	18	0.0041	0.61	11.6	2.2	1	23	572	594	572	594	0.93
4	18	0.0049	0.73	11.3	0.4	2	23	598	619	597	619	0.96
5	18	0.037	5.6	8.6	5.8	1	23	689	711	689	712	0.95
6	18	0.00041	0.061	14.7	0.6	1	21	718	738	718	742	0.92
7	18	0.026	3.9	9.0	5.0	2	23	823	844	822	844	0.95
8	18	0.00024	0.036	15.4	4.2	1	23	898	920	898	920	0.96
9	18	0.00031	0.046	15.1	0.7	1	20	925	944	925	946	0.94
10	18	0.046	6.8	8.3	0.5	2	23	957	978	957	978	0.97
11	18	1.4e-05	0.0021	19.3	0.7	2	23	1017	1038	1016	1038	0.97
12	18	2.8e-05	0.0042	18.4	1.6	1	23	1043	1065	1043	1065	0.95
13	18	0.00016	0.024	16.0	2.9	1	23	1071	1093	1071	1093	0.98
14	18	5e-06	0.00075	20.7	0.4	1	23	1109	1131	1109	1131	0.95
15	18	4.1e-07	6.1e-05	24.2	0.6	1	23	1137	1159	1137	1159	0.99
16	18	4.4e-05	0.0066	17.8	0.2	1	23	1165	1187	1165	1187	0.97
17	18	0.00016	0.024	16.0	4.1	1	23	1193	1215	1193	1215	0.96
18	18	0.012	1.7	10.2	0.4	1	20	1221	1240	1221	1242	0.89

Sequence Information

Coding Sequence: ATGGACGCCGTAGAAATAAATACATCGGATTCACCGCAAAACGAAGAAGGCATCGTGTCGACGGTAGAAATATGCCGTGTTTGCCTTCTTGGTAATCTAGTAATGCGGGACTTGTTTCTGGAAAACGAGGTTGCTTCTCTTTCGGCAAAAGCGATGAGTTTCGCTAACGTTAAGATGTTACCTGGGGATGGCTTACCAGCCCGCGTATGCTGCGTGTGCGCGGACAAACTGGAATCCGCGTACGAATTTAAATTACAAGTGGAACAAGCAGATACTGTTCTCAGAGAAAGATTTGTCACTATGAATATAAAAGAGGAGCTGTTCTTCGACGAAGTCGAAGTACACTTGGATACCAGAGAACGAAACGAGGGTATAGAAGGAATGCGTATAGAGAATCATTATCGGGATACTACAGAAACTTTACCACCAATGTCTCAAGAAGAGAAATCGTCTCTACTGAAGGATCAGCTTGATCTGTTGCAAATGGAAAAATTAACTGAAAATGAACAGGGTATTAGAGAGCAGAACAATGGTCAAGTAATGGAAGAAGTGATCGATCAAGCGATTAGCGCGGAACAGACATCGGAGGAACATCTAAACCAGGAAGAAGAGACCGTTAAAACTGTCCCGGATACCTCAAAAGACGACGAATCGTTGAAACATGAAAACAGGGAGGACGATTGCATCGCAAGAATTGCGCCGATGGAACACGATTATATATTGCAACAGGAGTGTATATTATCCGACGATGGTCAGCGAGAAcatcaagaagaagaagagcaaCCTCAAGAACAGCAGCAGCTTAACGATTCCGAAGAATCGTTTCCGCGAGAAGATTGCGcggaatatgtaaatttattggtAAAAGCGGCCGATGTAACGAATCAGGAAGACGAGGACGAGGACGAGGATGAACCAGGAGGTGCGGACGATATGAAACCGGATGTAAAAATGGAAGAAGGGTCTCCGTGTCAGAACGAAGCTAGGAGAAGTAAACGTAAACTGGTTCGTCGAAACCAAAGTATCGAAACGAAACGAGACTCCgacgaagaaaattattttgaaaatctaAATTTAAGTTCGAGATTAAAAAACGTCGAAGATTCTGATAAATCCGATAAGGTATTTTTCCTATGTTACCTGTGCGACAAAGAGTTTTTGTCGAAGAGCGTTTTGAAGGAGCATATGCACACTCACGAGGAAGTTAGAAAAGCATTGTCTCTGAAAAAGACGTTAGAGACGTTAGAAACGTTAGAAACGCCGCAAAAAAATGTTAGTAATCCCGTGAAATCGCCCCCCTCGGGTAAAAGATCGAATAAATGCCCTTACTGTGGCAAACAGTACATCTATATAATTTCGTTTAGCAAGCACTTGAAGAAACACGAACGGGAGAAGGAAGAGGGAAAGGAAGAACCGATGCCGTTAGAAATTTCGTTTCACGAGGATGAGCATAGTTTAGATCTTGACGATTACGAGGAGGCGCAGCGGTCGAATGCCGAGTTTCGAAGAAGAGCCAAAGGAAAAGACGGTTTCGACAGAACGAAGACGAAGAAACCGGTAGAAGAGGGCGAGTTCGAGGACGAGGACGACGAACAAGGGCAGGAGGAGAATGAAGAGGAAGAAAGGGGGAAGGAAGAGAATAGGGGTGATCAAGGAGACGACAGTTGGAACAGAGAAGAGAAAGAAGGAAGTCAGGGTGTGCGCACGGAAACGTTCGCTTGCGATAAATGCTCGCAGAAATTCTATACCAAGCGCGGTTTACGGAAACACTCGGTTTCGCACGTTGTTCTTAAATGCAGCGTTTGCGAAGAAGAGTTCGATTCGATGGAAAAGCTTAGAAACCATCGTGCAAAGCACGTGGTCGAGGGCGTATTGAGCGAACAAGATTTCGAAGCGGATACGGAGTACACGATCGACGATAGAACCGACGATCGCGCGACAGACGGGAAAGGAAACGATGGAAAGGCCCAAAATGGAGAGGATGGAGGCGAAGTGGAACGATTTGAAACGGATAACAGATCGGGGAAAAGCGACAGAAATACGGAGACGCACTCGGGGATCGAGTACAATTGCAAGACGTGTTGTCAGCGGTTTCCGAGGAAAGATTTGTTGCTGAAGCACATGGAACAGCATCACGAACGCGCGAAAGCTTACAAGTGTACACAATGCAATAAAACGTTCGGCAACGAACTTACTTTACGAAATCATCTTATAGCCACCGATCACAAAACTTTCGTTCACGGGCAAGAATACGATCCTAATAAACGCATTAAACGAGTCGCCGCGAGAGCGGCTCAGAAGATAATCGATCAGATTAAAACGGAGGACGGTTTAGAGGattacgacgacgacgacgacgaggacgaTCAGAGCAACGTCAGGCTCGATCGCGTCGGTTCAGGGTTAGACGGTCGCGGTAAACGAGACGCGTCCATGCAAAAGAAACACAATTACAAGAAGGAGCTGGAATGCGTGAGTTGCAATAAAAAATGCTGTTCGAAGCAATCGTTGGCAAAACACATGGAACAGCACGTGAAAGACGAACGAACCGTGAAATTGGAAAAGCAGAAACAACCGGCGGAGAAAAAGGGACAACGAAACTGTACCGGCGAACGCGTCGATAACGGGGAGAACAAAGATGACGATTATGACTCGGATTTCGAGAGTGGATTAGACTGGCCAATGGACAATCACGAGTGTGCCAAGTGTAAGAAACGGTACAGTACGAAAAAATCATTGTTGCGACATCAGTTATTGCACGAGGAGCCGAACTTCGAATGCGACATCTGTAACGTGAAATTCTACCGTAAAGACAAATTGAAGGCTCATTACGACAAGTGTTCGGAAAAGAATCCTGATCAAGTGAGAAAGTGCAACATCTGCGGAGATAGTTTCGAAAACAACGAAATCCTACGAGAGCACAGATCGAAACACGTTACCGAGGGTATCCTTACGGAGGAAGATTTGAGGGATACGGAACCGCGGCCGGAAGAGAAAAAACCGGGCGAGAAAATCGGTCGGAAGAGAAGAACCGACATCGTCGGTTTAGAATGTACCGAATGCAACAAACGATACACCTCGAGGAAAGGACTATTGCGACATATTCAAGTTCACGAGGGGAAGAAATACCTGTGCGATATATGTCCGAAAAAGTTTTACAGGAGAGAACATTTGAAGATACACGTGGCTAAGCATAATATGATAAAACCGTACAAGTGTACTCGTTGCACCAAGCGTTTCATTAAAGAGGAGCAATTGACCAATCATTTGTCGAAGCATGATCGTACTTTCAAGAAGAATAAAGAGACGGATAGTTCGAAGAGGTTCCTTTGCGAGATCTGTTCGAAAAGTTTCACCCAGTCGACCACGTTAATCGCTCATCTTCGAGCACATAACGGGATCAAACCATACGTTTGCGAAGTTTGTTCGCGACCGTTTACAACGAACGCGTACCTAAAAATGCACATGAGAACGCATACGCAAGAACGACCGTATATCTGCCAGTACTGTTCACGAGCATTCGCCAGGGCCGACACGCTCGCCAATCATTTGACTTCGCACACGGGCGAAGCAAAGTATCATTGCAAATATTGCCCGAAAAATTTCCGCCGTCTCAAGTCCCTGAAAGAGCACGTATTCATTCACACCGGTCAAAGGCCTTACGCTTGTCCAACCTGTGATCGACGGTTCAACAATAACGGAAGTCGTTACGCTCATAGTAAAAGGTGTAAacaaaatttcgtacaaaatcaGACACAAAACCAGAATCAGAATCAGAATCGTGGTCAGATATTGGCCACGCAAGCGCAATCGATTCAAACTCAACAGAAAGTGTTACACCAGGCCACTCTTGGACAATGTCAAGTGGTGAAGGCACAGAATATCAAAACGATCACTATTACCAGACAATCTGAACCGGTTACTGCTCAACAGGTTATGCAACATCAGGAAATACTGATGCCTTTGATTCTTCCGCTTACCGTCACTCTCGCCGACGTTGGCGAAGAAGTTATATTACCAGAGGGAAGTAAAATATTTACTACCACTTAA
Protein Sequence: MDAVEINTSDSPQNEEGIVSTVEICRVCLLGNLVMRDLFLENEVASLSAKAMSFANVKMLPGDGLPARVCCVCADKLESAYEFKLQVEQADTVLRERFVTMNIKEELFFDEVEVHLDTRERNEGIEGMRIENHYRDTTETLPPMSQEEKSSLLKDQLDLLQMEKLTENEQGIREQNNGQVMEEVIDQAISAEQTSEEHLNQEEETVKTVPDTSKDDESLKHENREDDCIARIAPMEHDYILQQECILSDDGQREHQEEEEQPQEQQQLNDSEESFPREDCAEYVNLLVKAADVTNQEDEDEDEDEPGGADDMKPDVKMEEGSPCQNEARRSKRKLVRRNQSIETKRDSDEENYFENLNLSSRLKNVEDSDKSDKVFFLCYLCDKEFLSKSVLKEHMHTHEEVRKALSLKKTLETLETLETPQKNVSNPVKSPPSGKRSNKCPYCGKQYIYIISFSKHLKKHEREKEEGKEEPMPLEISFHEDEHSLDLDDYEEAQRSNAEFRRRAKGKDGFDRTKTKKPVEEGEFEDEDDEQGQEENEEEERGKEENRGDQGDDSWNREEKEGSQGVRTETFACDKCSQKFYTKRGLRKHSVSHVVLKCSVCEEEFDSMEKLRNHRAKHVVEGVLSEQDFEADTEYTIDDRTDDRATDGKGNDGKAQNGEDGGEVERFETDNRSGKSDRNTETHSGIEYNCKTCCQRFPRKDLLLKHMEQHHERAKAYKCTQCNKTFGNELTLRNHLIATDHKTFVHGQEYDPNKRIKRVAARAAQKIIDQIKTEDGLEDYDDDDDEDDQSNVRLDRVGSGLDGRGKRDASMQKKHNYKKELECVSCNKKCCSKQSLAKHMEQHVKDERTVKLEKQKQPAEKKGQRNCTGERVDNGENKDDDYDSDFESGLDWPMDNHECAKCKKRYSTKKSLLRHQLLHEEPNFECDICNVKFYRKDKLKAHYDKCSEKNPDQVRKCNICGDSFENNEILREHRSKHVTEGILTEEDLRDTEPRPEEKKPGEKIGRKRRTDIVGLECTECNKRYTSRKGLLRHIQVHEGKKYLCDICPKKFYRREHLKIHVAKHNMIKPYKCTRCTKRFIKEEQLTNHLSKHDRTFKKNKETDSSKRFLCEICSKSFTQSTTLIAHLRAHNGIKPYVCEVCSRPFTTNAYLKMHMRTHTQERPYICQYCSRAFARADTLANHLTSHTGEAKYHCKYCPKNFRRLKSLKEHVFIHTGQRPYACPTCDRRFNNNGSRYAHSKRCKQNFVQNQTQNQNQNQNRGQILATQAQSIQTQQKVLHQATLGQCQVVKAQNIKTITITRQSEPVTAQQVMQHQEILMPLILPLTVTLADVGEEVILPEGSKIFTTT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01122592;
90% Identity: iTF_00963981;
80% Identity: -