Basic Information

Insect: Megachile leachella
Gene Symbol: -
Assembly: GCA_963576845.1
Location: OY756255.1:9911952-9916912[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 0.22 32 6.2 7.8 1 23 30 53 30 53 0.96

2 19 3.5e-06 0.00053 21.2 0.3 1 23 59 81 59 81 0.97

3 19 5.6e-06 0.00083 20.6 1.3 1 23 87 109 87 109 0.97

4 19 0.0019 0.28 12.6 0.8 1 23 115 137 115 137 0.98

5 19 0.00025 0.037 15.4 3.8 1 23 143 166 143 166 0.96

6 19 0.00088 0.13 13.7 2.1 1 23 181 204 181 204 0.94

7 19 0.00076 0.11 13.9 0.1 1 23 212 234 212 234 0.96

8 19 8.1e-06 0.0012 20.1 1.7 2 23 241 262 241 262 0.98

9 19 5.4e-06 0.00081 20.6 1.4 2 23 269 290 269 290 0.97

10 19 0.047 7 8.3 0.8 2 23 328 350 327 350 0.96

11 19 1.4e-05 0.0021 19.4 1.0 1 23 356 379 356 379 0.98

12 19 0.24 37 6.0 0.1 2 23 385 407 384 407 0.94

13 19 5.2e-05 0.0077 17.6 0.6 1 23 412 434 412 434 0.98

14 19 0.015 2.3 9.8 0.3 2 23 441 463 440 463 0.94

15 19 4.1e-06 0.00061 21.0 0.7 1 23 483 506 483 506 0.97

16 19 0.0049 0.73 11.3 0.1 1 23 517 539 517 539 0.94

17 19 0.0064 0.96 11.0 4.7 1 23 545 567 545 567 0.94

18 19 5.2e-07 7.9e-05 23.8 1.1 1 23 573 595 573 595 0.98

19 19 0.0003 0.045 15.1 3.2 1 23 601 624 601 624 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	0.22	32	6.2	7.8	1	23	30	53	30	53	0.96
2	19	3.5e-06	0.00053	21.2	0.3	1	23	59	81	59	81	0.97
3	19	5.6e-06	0.00083	20.6	1.3	1	23	87	109	87	109	0.97
4	19	0.0019	0.28	12.6	0.8	1	23	115	137	115	137	0.98
5	19	0.00025	0.037	15.4	3.8	1	23	143	166	143	166	0.96
6	19	0.00088	0.13	13.7	2.1	1	23	181	204	181	204	0.94
7	19	0.00076	0.11	13.9	0.1	1	23	212	234	212	234	0.96
8	19	8.1e-06	0.0012	20.1	1.7	2	23	241	262	241	262	0.98
9	19	5.4e-06	0.00081	20.6	1.4	2	23	269	290	269	290	0.97
10	19	0.047	7	8.3	0.8	2	23	328	350	327	350	0.96
11	19	1.4e-05	0.0021	19.4	1.0	1	23	356	379	356	379	0.98
12	19	0.24	37	6.0	0.1	2	23	385	407	384	407	0.94
13	19	5.2e-05	0.0077	17.6	0.6	1	23	412	434	412	434	0.98
14	19	0.015	2.3	9.8	0.3	2	23	441	463	440	463	0.94
15	19	4.1e-06	0.00061	21.0	0.7	1	23	483	506	483	506	0.97
16	19	0.0049	0.73	11.3	0.1	1	23	517	539	517	539	0.94
17	19	0.0064	0.96	11.0	4.7	1	23	545	567	545	567	0.94
18	19	5.2e-07	7.9e-05	23.8	1.1	1	23	573	595	573	595	0.98
19	19	0.0003	0.045	15.1	3.2	1	23	601	624	601	624	0.98

Sequence Information

Coding Sequence: ATGCTTGTTTTGTACAAATGTTCCTCCGAAAAAGATGATGATGTTATAAAGATgaaaaaGTCTCGAAGATCCGCCTCCCGACCAATTCACGAGTGCTTCAAATGCGGAGCATGCTTCTGTCACACAATAAAACTAGTGGAGCACCTGAAGAACCTCCATGGAATCGACAGAGCGTTCAGCTGCGACGAGTGCGGTAAAACGTTCAGAAGCCCCATGAACATCGCCCGCCACAAACTGATACACACAGGCTCGAAAAGATTCGCCTGCGACCTGTGCGACTACAGAACTAACCAGAAGTCGAATCTGGAGAGCCATCAGCGTCGTCACATGAAGGATTACGCTTTCAAGTGCGACCAGTGCGACAAGGGTTTCTTCCTGAGGAGGGAATACCTGGAGCACGTGAACGTCCACACTAGAAAACAACTGTTCCGCTGCGATCACTGCGACAAATCGTACCTTTACAAACGAAATTTAACTACGCATCTCAGGGCTCAGCACCCGAGTGTCCTGCATGTGGAGTCCAGTAGCGACAAACAGAAACACGCGTGCAGTGTCTGCTTGGAGAGTTTCGCGAGGAAGTTGTCTTTGAAGAAGCATTTGAAGCAACGACACGGTTTGCACGAGAAGACTAATTATTTGTGCGATCTGTGCGGGGCTGTGCTGTCCTCCAGAAGGGGATTGGTGGTCCACAGACGAACGCATACGAATGAGAAGATCGCCAAATGTGATATGTGCGAGAAACAGTTCACTAGTAAACAGAATCTTGAACTTCATCGACGAGTGCACACCGGCGAAAAACCTAATGTTTGCAAACAGTGTGGAAGAAGGTTCACGCAACGTACTTCTTTGATATTGCATTTGAGGTATCATTCGGGGGAGAGACCGTACCACGACTGGACCAATGAACAAGAGGAGATTGCTGGCTGCGAAGAAAACGAGGATGTTCTAGATTCAGAACAGAAattcgaaGGAAACGAAAAAAGCTGTGATATTTGCCAAGAGAAATTTCACTTCGTGACGAGATTAGTAGCCCACTTGAGGATCGTTCATGGTATCCAAAGACCTTTTAAATGTGGCACCTGTGATAAGACGTATCCTCAGCAGTTCATGTTGAACGCTCATGTGAAGAAATCACATACACCCAAAACGATACCATGTGCTCAGTGCAGTTTCATGGGGGTCGACACTTCTGATGTTGAAAGGCACATTAAACGACAACATAGCGAGGTCAAATTCACTTGCGAGATTTGTAGCGAGAATTTTAATGATAAGGAGTCCTTAGTGACGCATAGAACCATGCACAATTTTATGCCGTTTCAACAGTGCAATGCTTGTGGTAGCACCTTTGATGACGTGTACAGCCTGAAAGAGCACAATCGCCTCTACCACTACGACCCAGCAGTCTCCATCCAAGACAAGGTCGACAGCGACGAAAAGGGTGCCATGTACAAATGCGACGTCTGCGGCAAGGTATACATAGACAAATCAGTATTAAAGCAACACAAGATGAAATCCCACGGCGGTAAACGTAAGTACGAGAAACGGCGATACCTGTGTGCTCTTTGTGGCAAGGAATTGAAAACCGCCAAAGGTTTAGAGATCCACAATCGCTGGCACACAGGCGAAAAACCGTATACCTGCGAAGTGTGTGGCAAATGTTTCACGTGTGAAACACTGTTGAGGACTCATAATGTGACACACACTGGCGAGAGAAAGTATTCCTGCGATCAGTGTGGTAAAGCGTTTACACAGAGGTCCACGCTGGTGGTACATAAACGGTATCATACGGGAGAACGACCGTATGTTTGTACGCGTTGCAGTAAAGGGTTCGTGACGAGAACGGTTTTGAATACTCATATGAAGTCCTGTCACTGA
Protein Sequence: MLVLYKCSSEKDDDVIKMKKSRRSASRPIHECFKCGACFCHTIKLVEHLKNLHGIDRAFSCDECGKTFRSPMNIARHKLIHTGSKRFACDLCDYRTNQKSNLESHQRRHMKDYAFKCDQCDKGFFLRREYLEHVNVHTRKQLFRCDHCDKSYLYKRNLTTHLRAQHPSVLHVESSSDKQKHACSVCLESFARKLSLKKHLKQRHGLHEKTNYLCDLCGAVLSSRRGLVVHRRTHTNEKIAKCDMCEKQFTSKQNLELHRRVHTGEKPNVCKQCGRRFTQRTSLILHLRYHSGERPYHDWTNEQEEIAGCEENEDVLDSEQKFEGNEKSCDICQEKFHFVTRLVAHLRIVHGIQRPFKCGTCDKTYPQQFMLNAHVKKSHTPKTIPCAQCSFMGVDTSDVERHIKRQHSEVKFTCEICSENFNDKESLVTHRTMHNFMPFQQCNACGSTFDDVYSLKEHNRLYHYDPAVSIQDKVDSDEKGAMYKCDVCGKVYIDKSVLKQHKMKSHGGKRKYEKRRYLCALCGKELKTAKGLEIHNRWHTGEKPYTCEVCGKCFTCETLLRTHNVTHTGERKYSCDQCGKAFTQRSTLVVHKRYHTGERPYVCTRCSKGFVTRTVLNTHMKSCH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00961968;
90% Identity: iTF_00961968;
80% Identity: -