Mlag005015.2
Basic Information
- Insect
- Megachile lagopoda
- Gene Symbol
- -
- Assembly
- GCA_036983795.1
- Location
- CM072788.1:7409879-7414646[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 0.22 25 6.1 7.8 1 23 32 55 32 55 0.96 2 19 3.5e-06 0.00041 21.2 0.3 1 23 61 83 61 83 0.97 3 19 5.6e-06 0.00064 20.6 1.3 1 23 89 111 89 111 0.97 4 19 0.0019 0.22 12.6 0.8 1 23 117 139 117 139 0.98 5 19 0.00025 0.029 15.4 3.8 1 23 145 168 145 168 0.96 6 19 0.00049 0.057 14.5 2.2 1 23 183 206 183 206 0.94 7 19 0.00076 0.088 13.9 0.1 1 23 214 236 214 236 0.96 8 19 8e-06 0.00093 20.1 1.7 2 23 243 264 243 264 0.98 9 19 5.4e-06 0.00063 20.6 1.4 2 23 271 292 271 292 0.97 10 19 0.047 5.4 8.2 0.8 2 23 330 352 329 352 0.96 11 19 1.4e-05 0.0016 19.4 1.0 1 23 358 381 358 381 0.98 12 19 0.24 28 6.0 0.1 2 23 387 409 386 409 0.94 13 19 5.2e-05 0.006 17.5 0.6 1 23 414 436 414 436 0.98 14 19 0.015 1.8 9.8 0.3 2 23 443 465 442 465 0.94 15 19 4e-06 0.00047 21.0 0.7 1 23 486 509 486 509 0.97 16 19 0.0049 0.56 11.3 0.1 1 23 520 542 520 542 0.94 17 19 0.0064 0.74 11.0 4.7 1 23 548 570 548 570 0.94 18 19 5.2e-07 6.1e-05 23.8 1.1 1 23 576 598 576 598 0.98 19 19 0.00012 0.013 16.4 3.2 1 23 604 627 604 627 0.98
Sequence Information
- Coding Sequence
- ATgcttttatacaaatatttgtcaaaGTTCCtgcgaaaaataaatgatattatggagataaaaaaGTCCCGAAGATCCGCCTCTCGGCCGATCCACGAGTGCTTCAAATGCGGAGCGTGTTTCTGTCACACCATAAAATTAGTGGAGCACCTGAAGAACCTCCACGGGATCGACAGAGCGTTCAGCTGCGACGAGTGCGGCAAAACGTTCAGAAGCCCCATGAACATCGCCCGCCACAAGCTGATACACACAGGCTCGAAAAGGTTCGCCTGCGATCTGTGCGACTACAGAACTAACCAGAAATCGAATCTGGAGAGCCACCAGCGTCGTCACATGAAGGATTACGCTTTCAAGTGCGACCAGTGCGACAAGGGTTTCTTCCTGAGGAGGGAATACCTGGAGCACGTGAACGTCCACACAAGAAAACAACTGTTCCGCTGCGATCACTGCGACAAATCGTATCTTTACAAACGAAACCTGACTACGCATCTGAGGGCTCAGCACCCGAGTGTCCTGCATGTGGAGTCCAGCAGCGACAAGCAGAAACACGCGTGCAGTATCTGCTTGGAGAGTTTCGCGAGGAAGTTGTCCCTGAAGAAACACTTGAAGCAACGACACGGGCTACACGAGAAGACTAATTATTTATGCGATTTGTGCGGGGCTGTGCTGTCCTCCAGAAGGGGCTTGGTGGTCCACAGACGAACGCATACCAACGAGAAGATCGCCAAATGTGATATGTGCGAGAAGCAGTTCACTAGCAAACAGAACCTTGAACTTCATCGACGTGTGCACACTGGTGAAAAACCTAATGTTTGCAAGCAGTGCGGGAGAAGGTTCACGCAACGTACTTCTTTGATACTGCATCTGAGGTATCATTCGGGGGAGAGACCGTATCACGACTGGACCAATGAACAAGAGGAGATTGCTGGCTGCGAAGAAAACGAGGATGTTCTAGATTCAGAACAGAAattcgaAGGAAACGAAAAAAGCTGTGATATTTGCCAAGAGAAATTTCACTTCGTGACGAGATTAGTAGCCCACCTGAGGATCGTTCATGGTATCCAAAGACCCTTCAAATGTGGCACTTGTGATAAGACGTATCCTCAGCAGTTTATGTTGAACGCTCATGTGAAGAAATCGCATAcaccgaaaacgataccaTGTGCGCAGTGCAGTTTCATGGGGGTGGACACTTCTGATGTAGAGAGACACATTAAACGACAACATAGCGAGGTCAAATTCACTTGCGAGATTTGTAGCGAGAATTTTAATGATAAGGAGTCTTTAGTGACGCATAGAACGATGCACAATTTTATGCCGTTTCAACAGTGCAATGCTTGCGGTAGCACCTTTGATGACGTGTACAGTTTGAAGGAGCATAATCGCCTCTACCACTACGACCCTGCAGTGTCCATACAGGACAAGGTCGACGACAGCGAAGAAAAGGGTGCAATGTACAAATGCGACGTTTGCGGCAAGGTTTACATAGACAAATCAGTATTAAAGCAACACAAGATGAAATCTCACGGTGGTAAACGTAAGTACGAGAAGCGGCGATACCTGTGTGCTCTTTGTGGCAAGGAACTGAAAACCGCCAAAGGTTTGGAGATCCACAATCGCTGGCACACGGGCGAAAAACCGTATACCTGCGAAGTGTGTGGCAAGTGTTTCACGTGTGAAACACTGTTGAGGACTCACAATGTGACACACACGGGCGAGAGAAAGTATTCCTGCGATCAGTGTGGCAAAGCGTTTACACAGAGGTCCACGCTGGTGGTCCACAAACGTTATCACACGGGGGAAAGACCGTATGTTTGTACACGTTGCAATAAGGGTTTCGTGACTAGAACAGTTTTGAACACTCACATGAAGTCTTGTCACTGA
- Protein Sequence
- MLLYKYLSKFLRKINDIMEIKKSRRSASRPIHECFKCGACFCHTIKLVEHLKNLHGIDRAFSCDECGKTFRSPMNIARHKLIHTGSKRFACDLCDYRTNQKSNLESHQRRHMKDYAFKCDQCDKGFFLRREYLEHVNVHTRKQLFRCDHCDKSYLYKRNLTTHLRAQHPSVLHVESSSDKQKHACSICLESFARKLSLKKHLKQRHGLHEKTNYLCDLCGAVLSSRRGLVVHRRTHTNEKIAKCDMCEKQFTSKQNLELHRRVHTGEKPNVCKQCGRRFTQRTSLILHLRYHSGERPYHDWTNEQEEIAGCEENEDVLDSEQKFEGNEKSCDICQEKFHFVTRLVAHLRIVHGIQRPFKCGTCDKTYPQQFMLNAHVKKSHTPKTIPCAQCSFMGVDTSDVERHIKRQHSEVKFTCEICSENFNDKESLVTHRTMHNFMPFQQCNACGSTFDDVYSLKEHNRLYHYDPAVSIQDKVDDSEEKGAMYKCDVCGKVYIDKSVLKQHKMKSHGGKRKYEKRRYLCALCGKELKTAKGLEIHNRWHTGEKPYTCEVCGKCFTCETLLRTHNVTHTGERKYSCDQCGKAFTQRSTLVVHKRYHTGERPYVCTRCNKGFVTRTVLNTHMKSCH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00962650;
- 90% Identity
- iTF_00962650;
- 80% Identity
- -