Basic Information

Insect: Megachile lagopoda
Gene Symbol: -
Assembly: GCA_036983795.1
Location: CM072795.1:902032-906518[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 0.017 1.9 9.6 2.4 1 23 383 405 383 405 0.95

2 18 0.00083 0.096 13.8 0.9 2 23 446 467 445 467 0.98

3 18 0.0041 0.47 11.6 2.2 1 23 578 600 578 600 0.93

4 18 0.0049 0.57 11.3 0.4 2 23 604 625 603 625 0.96

5 18 0.028 3.2 9.0 6.2 1 23 695 717 695 718 0.95

6 18 0.00041 0.047 14.7 0.6 1 21 724 744 724 748 0.92

7 18 0.026 3 9.0 5.0 2 23 830 851 829 851 0.95

8 18 0.00024 0.028 15.4 4.2 1 23 905 927 905 927 0.96

9 18 0.0003 0.035 15.1 0.7 1 20 932 951 932 953 0.94

10 18 0.045 5.3 8.3 0.5 2 23 964 985 964 985 0.97

11 18 1.4e-05 0.0016 19.3 0.7 2 23 1024 1045 1023 1045 0.97

12 18 2.8e-05 0.0033 18.4 1.6 1 23 1050 1072 1050 1072 0.95

13 18 0.00016 0.018 16.0 2.9 1 23 1078 1100 1078 1100 0.98

14 18 5e-06 0.00058 20.7 0.4 1 23 1116 1138 1116 1138 0.95

15 18 4.1e-07 4.7e-05 24.2 0.6 1 23 1144 1166 1144 1166 0.99

16 18 4.4e-05 0.0051 17.8 0.2 1 23 1172 1194 1172 1194 0.97

17 18 0.00016 0.019 16.0 4.1 1 23 1200 1222 1200 1222 0.96

18 18 0.012 1.3 10.2 0.4 1 20 1228 1247 1228 1249 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	0.017	1.9	9.6	2.4	1	23	383	405	383	405	0.95
2	18	0.00083	0.096	13.8	0.9	2	23	446	467	445	467	0.98
3	18	0.0041	0.47	11.6	2.2	1	23	578	600	578	600	0.93
4	18	0.0049	0.57	11.3	0.4	2	23	604	625	603	625	0.96
5	18	0.028	3.2	9.0	6.2	1	23	695	717	695	718	0.95
6	18	0.00041	0.047	14.7	0.6	1	21	724	744	724	748	0.92
7	18	0.026	3	9.0	5.0	2	23	830	851	829	851	0.95
8	18	0.00024	0.028	15.4	4.2	1	23	905	927	905	927	0.96
9	18	0.0003	0.035	15.1	0.7	1	20	932	951	932	953	0.94
10	18	0.045	5.3	8.3	0.5	2	23	964	985	964	985	0.97
11	18	1.4e-05	0.0016	19.3	0.7	2	23	1024	1045	1023	1045	0.97
12	18	2.8e-05	0.0033	18.4	1.6	1	23	1050	1072	1050	1072	0.95
13	18	0.00016	0.018	16.0	2.9	1	23	1078	1100	1078	1100	0.98
14	18	5e-06	0.00058	20.7	0.4	1	23	1116	1138	1116	1138	0.95
15	18	4.1e-07	4.7e-05	24.2	0.6	1	23	1144	1166	1144	1166	0.99
16	18	4.4e-05	0.0051	17.8	0.2	1	23	1172	1194	1172	1194	0.97
17	18	0.00016	0.019	16.0	4.1	1	23	1200	1222	1200	1222	0.96
18	18	0.012	1.3	10.2	0.4	1	20	1228	1247	1228	1249	0.89

Sequence Information

Coding Sequence: ATGGACGCCGTAGAAATAAATACATCGGATTCACCGCAAAACGAAGAAGGCATCGTGTCGACGGTAGAAATATGCCGTGTTTGCCTTCTTGGTAATCTAGTGATGCGGGACTTGTTTCTGGAAAACGAGGTTGCTTCCCTTTCGGCGAAAGCGATGAGTTTCGCTAACGTTAAGATGTTACCTGGGGATGGTTTACCAGCCCGCGTATGCTGTGTGTGCGCGGACAAACTAGAATCCGCATACGAATTTAAGTTACAAGTGGAACAAGCCGATACCGTTCTCAGAGAAAGATTTGTCActatgaatataaaagaagAGTTGTTCTTCGATGAAGTCGAAGTACACTTGGATACCAGAGAACGAAACGAGGGTATAGAAGGAATGCGTATAGAGAATCATTATCGGGATACTACAGAAACCTTACCACCGATGTCTCAGGAAGAGAAATCGTCTCTATTGAAGGATCAGCTGGATCTGTTGCAAATGGAAAAACTAACCGAAAATGAACAGGGTATTAGAGAGCAGAACAATGGCCAAGTAATGGAAGAAGTGATCGATCAAGCGATTAGCGCGGAACAGATATCGGAGAATCGTCTAAATCATGAAGAAGAGACCGTTAAAACTGTCGCGGATAACTCGAAAGACGACGAATCGTTGAAACATGAAAACAGGGAGGACGATTGCATCGGAAGAATTGCGCCAATGGAACACGATTATATATTGCAACAAGAGTGTATATTGTCCGACGATGGTCAACGAGAGCAtcaagaagaagaggaagaagaagaagaacaacCGCAagaacaacaacagcagcagcttAACGATTCCGAAGAATCGTTTCCGCGAGAAGATTGCGcggaatatgtaaatttattggTAAAGGCGGCCGATGTAACGAATCAGGAAGACGAAGACGAGGACGAGGATGAACCAGGAGGTTCGGACGATACGAAACCGGATGTAAAAATGGAAGAAGGGTCACCGTGTCAGAACGAAGCTAGGAGAAGTAAACGTAAACTGGTTCGACGAAACCAAAGtatcgaaacgaaacgagactccgacgaagaaaattatttcgaaaatctaaatttaagTTCGAGATTAAAAAACGTCGAAGATTCCGATAAATCCGATAAGATATTTTTCCTATGTTACCTGTGCGACAAAGAGTTTTTGTCGAAGAGCGTTTTGAAAGAACATATGCATACTCACGAGGAAGTTAGAAAAGCATTGTCTCTAAAAAAGACGTTAGAGACGTTAGAAACGTTCGAAACGCCGCAAAAGAATGTTAGCAATCCCGTGAAATCGCCCCCGTCGGGTAAAAGATCGAATAAATGCCCTTACTGTGGCAAACAGTACATCTATATAATTTCGTTTAGTAAACACTTGAAGAAACACGAACGGGAGAAGGAAGAGGGAAAGGAAGAGCCGATGCcgttagaaatttcatttcacgaGGACGAGCATAGTTTGGATCTTGACGATTACGAGGAGGCGCAGCGTTCGAATGTCGAGTTTCGAAGAAGAGCCAAAGGAAAAGACGGTTTCGACAGAACGAAGACGAAGAAATCGGTAGAAGAAGGCGAGTTCGAAGAGGAGGACGAGGAACAAGGGCAGGAGGAgaacgaagaggaagaaaggGGGAAGGACGAGGATAGGGGCGATCAAGGAGACCACGGTTGGAAcggagaagagaaagaaggaagTCAGGGCGTTCGCGCGGAAATGTTCGCTTGCGATAAATGCTCGCAGAAATTCTATACCAAGCGCGGTTTACGGAAACACTCGGTTTCGCACGTTGTTCTTAAATGCAGCGTTTGCGAAGAAGAATTCGATTCGATGGAAAAGCTTAGAAACCATCGTGCGAAGCACGTGGTCGAGGGCGTATTAAGCGAACAAGACTTCGAAGCGGATACGGAGTACACGATCGACGAAAGAACCGACGATCGCGGAACAGACGGGAAAGGAAACGATGGAAAGGTCCAAAATGGAGAGGATGGAGGCGAAGTGGAACGATTTGAAACGGATAACAGATCGGGGAAAAGCGACAGAAATACGGAGACGCACTCGGGGATCGAGTACAATTGCAAGACGTGTTGTCAGCGGTTTCCGAGGAAAGATTCGTTGCTGAAGCACATGGAACAGCATCACGAACGCGCGAAAACTTACAAGTGTACACAATGCAATAAAACGTTCGGCAACGAACTTACTTTACGAAATCATCTTATAGCCACCGATCATAAAACTTTCGTTCACGGGCAAGAATACGATCCTAATAAGCGCATTAAACGAGTCGCCGCGAGAGCGGCTCAGAAGATCATCGATCAGATTAAAACGGAGGACGGTTTAGAGGATtacgacgacgatgacgacgacgaggacgaTCAGAGCAACGTCAGGCTCGATCGTGTCGGTTCAGGGTTAGACGGTCGCGGTAAACGAGAAACGTCGATGCAAAAGAAACACAATTACAAAAAGGAGCTGGAATGCGTGagttgcaataaaaaatgctGTTCGAAGCAGTCGTTGGCAAAACACATGGAACAACACGTGAAAGACGAACGAACCGTAAAATTGGAAAAGCAGAAACAACCGACGGAGAAAAAGGGACCACGGAACTGTACCGGCGAACGCGTCGATAACGGGGAGAACAAAGATGACGATTACGACTCGGATTTCGAGAGTGGGTTAGACTGGCCGATGGACAATCACGAGTGTGCCAAATGTAAGAAACGGTACAGTACGAAAAAATCGTTGTTGCGACATCAGTTATTGCACGAGGAGCCGAACTTCGAATGCGACATCTGTAACGTGAAATTCTACCGTAAAGACAAATTGAAGGCTCATTACGACAAATGTTCGGAAAAGAATCCTGATCAAGTGAGAAAATGCAACATCTGCGGAGATAGTTTCGAAAACAACGAAATCCTACGAGAGCACAGATCGAAACACGTTACCGAGGGTATCCTTACGGAGGAAGATTTGAGGGATACGGAACCGCGGCCGGAAGAGAAAAAACCGGGCGAGAAAATCGGCCGGAAGAGAAGAACCGACATCGTCGGTTTAGAATGTACCGAATGCAACAAACGATACACCTCGAGGAAAGGACTATTACGACATATTCAAGTTCACGAGGGGAAGAAATACCTGTGCGATATATGTCCGAAAAAGTTTTACAGGAGAGAACATTTGAAGATACACGTAGCTAAGCATAATATGATAAAACCGTACAAGTGTACCCGTTGCACCAAGCGTTTCATTAAAGAGGAGCAATTGACCAATCATTTGTCGAAGCATGATCGTACTTTCAAGAAGAATAAAGAAACGGACAGTTCAAAGAGATTCCTTTGCGAGATCTGTTCGAAAAGTTTCACCCAATCGACCACGTTAATCGCTCATCTTCGAGCGCACAACGGAATCAAACCGTACGTTTGCGAAGTTTGTTCGCGACCGTTTACAACGAACGCGTACCTAAAAATGCATATGAGAACGCATACGCAAGAACGACCGTATATCTGTCAGTACTGTTCACGAGCATTCGCCAGGGCCGATACGCTCGCTAATCATTTGACTTCGCACACGGGCGAAGCCAAGTATCATTGCAAATATTGTCCGAAAAATTTCCGTCGTCTCAAATCCCTGAAAGAGCACGTTTTCATTCACACCGGTCAGCGGCCTTACGCTTGTCCAACCTGTGATCGACGGTTCAACAACAACGGAAGTCGTTACGCTCACAGTAAAAGGTGTAAGCAAAATTTCGTTCAAAATCAGACTCAGAACCAGAGTCAGAATCAGACTCGTGGTCAGATATTGGCCACGCAAGCGCAATCGATTCAAACTCAACAGAAAGTGTTACATCAGGCTACTCTTGGACAATGTCAAGTAGTGAAGGCACAGAATATCAAAACGATCACTATTACCAGACAATCTGAACCGGTTACTGCTCAACAGGTTATGCAACATCAGGAAATACTGATGCCTTTGATTCTTCCGCTTACCGTCACTCTCGCCGACGTTGGCGAAGAAGTTATATTACCAGAGggaagtaaaatatttactaccACTTAA
Protein Sequence: MDAVEINTSDSPQNEEGIVSTVEICRVCLLGNLVMRDLFLENEVASLSAKAMSFANVKMLPGDGLPARVCCVCADKLESAYEFKLQVEQADTVLRERFVTMNIKEELFFDEVEVHLDTRERNEGIEGMRIENHYRDTTETLPPMSQEEKSSLLKDQLDLLQMEKLTENEQGIREQNNGQVMEEVIDQAISAEQISENRLNHEEETVKTVADNSKDDESLKHENREDDCIGRIAPMEHDYILQQECILSDDGQREHQEEEEEEEEQPQEQQQQQLNDSEESFPREDCAEYVNLLVKAADVTNQEDEDEDEDEPGGSDDTKPDVKMEEGSPCQNEARRSKRKLVRRNQSIETKRDSDEENYFENLNLSSRLKNVEDSDKSDKIFFLCYLCDKEFLSKSVLKEHMHTHEEVRKALSLKKTLETLETFETPQKNVSNPVKSPPSGKRSNKCPYCGKQYIYIISFSKHLKKHEREKEEGKEEPMPLEISFHEDEHSLDLDDYEEAQRSNVEFRRRAKGKDGFDRTKTKKSVEEGEFEEEDEEQGQEENEEEERGKDEDRGDQGDHGWNGEEKEGSQGVRAEMFACDKCSQKFYTKRGLRKHSVSHVVLKCSVCEEEFDSMEKLRNHRAKHVVEGVLSEQDFEADTEYTIDERTDDRGTDGKGNDGKVQNGEDGGEVERFETDNRSGKSDRNTETHSGIEYNCKTCCQRFPRKDSLLKHMEQHHERAKTYKCTQCNKTFGNELTLRNHLIATDHKTFVHGQEYDPNKRIKRVAARAAQKIIDQIKTEDGLEDYDDDDDDEDDQSNVRLDRVGSGLDGRGKRETSMQKKHNYKKELECVSCNKKCCSKQSLAKHMEQHVKDERTVKLEKQKQPTEKKGPRNCTGERVDNGENKDDDYDSDFESGLDWPMDNHECAKCKKRYSTKKSLLRHQLLHEEPNFECDICNVKFYRKDKLKAHYDKCSEKNPDQVRKCNICGDSFENNEILREHRSKHVTEGILTEEDLRDTEPRPEEKKPGEKIGRKRRTDIVGLECTECNKRYTSRKGLLRHIQVHEGKKYLCDICPKKFYRREHLKIHVAKHNMIKPYKCTRCTKRFIKEEQLTNHLSKHDRTFKKNKETDSSKRFLCEICSKSFTQSTTLIAHLRAHNGIKPYVCEVCSRPFTTNAYLKMHMRTHTQERPYICQYCSRAFARADTLANHLTSHTGEAKYHCKYCPKNFRRLKSLKEHVFIHTGQRPYACPTCDRRFNNNGSRYAHSKRCKQNFVQNQTQNQSQNQTRGQILATQAQSIQTQQKVLHQATLGQCQVVKAQNIKTITITRQSEPVTAQQVMQHQEILMPLILPLTVTLADVGEEVILPEGSKIFTTT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01122592;
90% Identity: iTF_00963981;
80% Identity: -