Mfla015111.1
Basic Information
- Insect
- Mecyna flavalis
- Gene Symbol
- -
- Assembly
- GCA_949319885.1
- Location
- OX439426.1:11140434-11153467[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.0016 0.14 13.6 0.4 2 23 232 254 231 254 0.94 2 11 3.2 2.8e+02 3.2 0.2 5 23 263 281 261 281 0.92 3 11 0.00083 0.073 14.5 3.1 1 23 314 337 314 337 0.93 4 11 0.098 8.7 7.9 0.3 5 23 346 364 345 364 0.95 5 11 5e-05 0.0044 18.3 2.0 1 23 400 422 400 422 0.97 6 11 0.0032 0.28 12.6 1.0 1 23 431 454 431 454 0.97 7 11 0.00028 0.025 15.9 0.2 1 23 460 482 460 482 0.97 8 11 1.5e-06 0.00013 23.1 4.2 1 23 488 510 488 510 0.98 9 11 0.00015 0.013 16.8 1.1 1 23 515 537 515 537 0.98 10 11 5.6e-05 0.005 18.1 6.2 1 23 543 565 543 565 0.97 11 11 0.00029 0.026 15.9 2.1 2 23 572 594 571 594 0.95
Sequence Information
- Coding Sequence
- ATGGCTAAGTTGAACATAAAAGAATTATGCAGGCTATGTGCTAAAAGGGATGATTTTACAAAGGATTTATTCGACATGAATAATAAAAGTGCTTTAAAATTAGTCAAGGAACTAGTTAATATTGTCATACATGAAAATGATGAGTTGCCAACTAAAATCTGTCTGAACTGTGAAGAAAAAATGGTGTCATTTCAACTATTTGTTCTTGAATGTTTTAAAGCTCAAGAGACTCTGAAGAAAATGTATTTAGAAGCTTCTGATATCACAGTTAAACTTGAGTCCTTTGATTTTGGTCCAACACCTCTAATTAAGTCTGAAGTCAAAGATGAAATGTCAGCCGAGGATATTGTTTTATGTGCAATAAGAAATCAAAATGCTGATACTATCTTTGAAAACAGAGGTGATTTTAATGTTGAATTTAATCCTGATGATGACATTGACAATggtgatgatcatcataatgaAGGTCTTCCTGAGGATGATGATGACgacgacgatgatgatgatgatgatgatttattgacattagcttctctaaaaaaagaaaaagtacaGGATACAGTAATAAAACCAGAAAAGGAAAAAGTAAAGCGTTATAGGTCTTATAAGAAAAAAGCAATTTGTCAGGATTCTGCTGAAGTCGAAAAAGTTCTCCAGAAAGCTGATTGGAAAGTGAGAGATTTTGTGAAaCTCCAATGTGATATTTGTGATCAGAAAATGAAATCATGGAGTGAATTGCGTGTTCATTACTTTAAGATACATAAGACCAAACCATTGGTTAATTGTGTATGTGGCTTTGTCATCAGATCAAAGAGTGTTCTATATAAGCATGTGTCAGATCATAAAATAAGGAGCCAGAAAGCAAGTGGTATTGAAAACAAACCAGAGAATGAAGCAGATTCAAAATACTCCAGccttaaaattaatgattttgtAACgtttaattGTACAGTCTGCCAGAAAAAGTGCTCAAGCTGGTACAGTTTGCGTTCTCATAGTGAAAGGGCACATAATATTGCACCAGTGGTTCAATGCATTTGTGGAATCACACTGAAATCTAAGTCTGTTCTTTACAAACACATTCAAGATCATAAGAATCCAAATATGCTTTGCTGTGACAAGTTTCCTAGAATAACGAAAACAATAGAAGCACTTAATAAGCACAAGATGAGGCACATACCGAAATCAGAAAGAAAGTTTTGCTGTGTTACATGTGATAAgatatttataacaaaagatgCTTTGAAATCTCATGAAAGATCTCACATTCCCATCGAAGACAGAAAAATATACCACTGCGGTGTTTGCGAACTGAAATTCACGACACGCTCGTCAGCTGCATCGCACAAGCGCGTAGTGCACGACAAGATCAAGAGCTATGTTTGCGATCTGTGCGGATACGCGTGCGGCACCAACGGCGAGCTGCGCCAGCACCGCGCTATACACAGCGACGAGAAACCATTCGTCTGCAAGACGTGTTCTAAGCCGTTCAAGACCCACTCGAATCTCAAGACTCACATGGACACCCACGAGGACACGTCGTACCAGTGCTACGTGTGCAACCGCGTGCTGAACAGCCGGCGCACGCTGCGCAAGCACTTGCTGGTCCACGAGGAGAAGTGCAGGCACGTCTGCTCCTACTGCCACAAGGCTTTCAAGAGACGGCAGACGCTCAAGGTGCATCTCTACACGCATACTGGCGACAAGCCGCTGACGTGCAAGTGGTGCGACGAGCGGTTCGCGTACGCGTCGACGCTGCGCTCGCACCGCCTGCGCTGCCACCCGGACAAGATGGCGGCGCAGGCGGCCACCAACGCCTACGCTGCTTACGCGCACGTGTCTCAAGCCGTGCAGGAGGATTACATTAAAAACGACGTGGCGACGAATGCAGTCAACATTGCGAAAAATGAAGCTGAGGCTATGTAG
- Protein Sequence
- MAKLNIKELCRLCAKRDDFTKDLFDMNNKSALKLVKELVNIVIHENDELPTKICLNCEEKMVSFQLFVLECFKAQETLKKMYLEASDITVKLESFDFGPTPLIKSEVKDEMSAEDIVLCAIRNQNADTIFENRGDFNVEFNPDDDIDNGDDHHNEGLPEDDDDDDDDDDDDDLLTLASLKKEKVQDTVIKPEKEKVKRYRSYKKKAICQDSAEVEKVLQKADWKVRDFVKLQCDICDQKMKSWSELRVHYFKIHKTKPLVNCVCGFVIRSKSVLYKHVSDHKIRSQKASGIENKPENEADSKYSSLKINDFVTFNCTVCQKKCSSWYSLRSHSERAHNIAPVVQCICGITLKSKSVLYKHIQDHKNPNMLCCDKFPRITKTIEALNKHKMRHIPKSERKFCCVTCDKIFITKDALKSHERSHIPIEDRKIYHCGVCELKFTTRSSAASHKRVVHDKIKSYVCDLCGYACGTNGELRQHRAIHSDEKPFVCKTCSKPFKTHSNLKTHMDTHEDTSYQCYVCNRVLNSRRTLRKHLLVHEEKCRHVCSYCHKAFKRRQTLKVHLYTHTGDKPLTCKWCDERFAYASTLRSHRLRCHPDKMAAQAATNAYAAYAHVSQAVQEDYIKNDVATNAVNIAKNEAEAM
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00365145;
- 90% Identity
- -
- 80% Identity
- -