Mfla012691.1
Basic Information
- Insect
- Mecyna flavalis
- Gene Symbol
- -
- Assembly
- GCA_949319885.1
- Location
- OX439422.1:5463858-5472808[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 0.015 1.4 10.5 1.7 1 23 182 205 182 205 0.90 2 18 0.0062 0.55 11.7 0.3 1 23 278 300 278 300 0.98 3 18 0.001 0.089 14.2 0.2 1 23 304 326 304 326 0.95 4 18 0.017 1.5 10.3 0.1 2 23 332 354 331 354 0.88 5 18 0.022 1.9 10.0 5.3 1 23 360 383 360 383 0.93 6 18 1.4e-05 0.0013 20.0 0.2 1 23 390 413 390 413 0.98 7 18 4.3e-05 0.0037 18.5 3.2 1 23 419 441 419 441 0.96 8 18 2.2e-06 0.00019 22.6 2.6 1 23 447 469 447 469 0.98 9 18 0.0002 0.018 16.4 6.4 1 23 475 497 475 498 0.95 10 18 0.055 4.9 8.7 0.1 1 23 617 640 617 640 0.96 11 18 0.15 13 7.3 0.0 2 23 665 687 664 687 0.96 12 18 0.062 5.5 8.6 0.3 1 23 711 733 711 733 0.96 13 18 0.00076 0.067 14.6 0.2 1 23 737 759 737 759 0.98 14 18 0.00061 0.053 14.9 0.5 1 23 764 787 764 787 0.96 15 18 0.0087 0.76 11.3 0.4 2 23 794 816 794 816 0.93 16 18 0.034 3 9.4 6.3 1 23 823 846 823 846 0.96 17 18 6.4e-05 0.0057 18.0 4.9 2 23 853 874 852 874 0.96 18 18 3.9e-05 0.0034 18.6 0.6 1 23 880 902 880 902 0.99
Sequence Information
- Coding Sequence
- ATGAGCTTTCTTTTTGAGTTCCATGCTGGACTGGCTGCTGGGATGGGGGCTGACTCTTGGGCTGGGCTGTGTGTTGACATGGGTTCTGAAATGGCTTACGCGTTGAGGGTTGCGATAAGGGGTAAACTGTGGGCCGACTTTCTGGCTGGGATGGGGATTGACTTTTGGGCTGGGCTCCTATGGGTCAAGTATACGCAAAAATCATACAACGCCCTTCGCGTGCAGTATAATAATGGTTTTAGAATGTTGTTGGGGCTGCCGCGGTGGTGTAGCGCATCAGAAATGTTCGCGGAGGCACGAACTGACGGTTTTTTAGCCGTCATTCGGAACCGAGTAGCTTCCCTGCTGCACCGCGTGCGAGGTGACGATCACTTGCCGCCAATCGTCAGTTCAGAAACAGAAACGACTGAATATAAACCGAAGAACTCTCTAGATCCAACACAGCTGAAGAATCTTAACGACGAATTGAAAGCGAGGAAGAAAAGAGCGACCCTCCTTCTGGAGTTGACAAGGATATGCCCTTTTCGGTGGACCAAGAACTTGTATCTCTGTTTTTACTGTGATCAACAGTTTTCCGATCCTGCTAGGCTAAGAGAACATCACTCTTTCGAGCATATATCCCAAACGCCGGCGGAAATAAGACAGGCCATATCACAGTTGAAGAAACACGAACTAATCAAAGTAGAAATCACAGATGTGAGCTGCAAACTCTGCGATGATTACATAATCGACTTCTTCGAACTTAAAACGCATCTCCTAGTGAAACATAAGAAGAATGTCGACCCTAAATCTAACGATGGGTTGTTGCCGTTCAAAGTTACGAAGAACGATTTCCAATGCGCGATTTGTGGCGATAAATACGTTGAGTTTAAGACATTGAACCAGCATATGAACGTACATTTCCAGAATTTCATATGCGAACAATGCGGTACTGGATTTATAACTCCGGATCGTTTGAGGACACATGCTTTTTCGCATGAAAGCGGTTCGGTTCCTTGCGATGGTTGTGATAAAGTTTTCAGATCGACTAATGCTAAGAACGAACATTACGCGAACGTTCACATGCAAGTGAAGAGACATAGATGCCCACATTGCTCAGAAACATTCCGGAATTACTTTCAGAGGAACAAACATGTATCGAATATACATGGTTTGAAGTTAAAGGAGTTTAAATGTACAATGTGTCCGAAAGTGTTTACATTAAGCGGAAAACTAGGCGTGCACATACGGACTGTCCATTTGAAAGTAAAGAGACACGCGTGTGATCATTGCGAATGGAAGTTTTACTCCAAATCTGAATTGAAGGAGCACATGATACGTCATGGAGGAGAGAGAAAGCACCAATGTAATGTTTGCAAGAAAGCGTACGCGAGGAAATATACTTTAAGAGAACATATGAGAATACATGATAATGACAGGAGATTTGTGTGCACGACTTGTGGGAGATCATTTGTGCAGAACTGTAGTTTGAAGCACCATGCGAAAATACACCATCGGCAGACTGTAGCGGCTAGAACCGACCAGAAAATATTACCGGATATATCGAAGCGGAAGAAAGTGGTGCCTCTGTTTCAAGTGGCGTACGACCGCACCTTGTGTAGGCCACTGGGGACCATCACCGACTTCACAAAGCTACGACAGAGAATTATACCTACGCTTGCTAAGCTTAGTTCAAGAAGTCCATCTCCACTGTCTATTTGCAGATCACCATCCCCCTTAAAGAATGATCCTCCCGAAACAACAGTAGTTCCTCCCAGACCGAAGCAAAAGAATCCAGATGTGAGACAAAATGCGCTTACAGTATTCGAATTTTCGACGGTTTATCCTTTTATTTACGGGAATAATAAGTTTAAATGCTTCATTTGTTCACAAGCATTCCTAGAGACGGCATTGCTAAGAGCTCATATGAATGAGGCACACACATTCGCTCCGCTAAAAAGGTTAGTTAATAACAGAcgagaaaatattttgaaagtcGATGTCAGCGAAATTGTCTGCAAAATCTGTTCAGCAGAACTTCCAGGGCTGACAGAGTTGAAGTCGCATCTCAAGACTGACCATAATAAACTAGTAGACCCAGAATTGAAGGATAATATTATACCTTTCAAGTTAGAGACAAGTGACGGCGGTTACAAATGCGTTATATGCGATGAGCACTTCATAAAAGTCCGTATTTTAGTAATACATATGAGCGTGCATTTTAACAACTATAGCTGTGAAGTTTGTGGCTCTGGATTCATGACTTTGAGGTTGCTGAAGAAACATTTGGAAGTTCATGAAAGTGGAAACTTCCCGTGTGATAGATGCAGTAAAGTCTTCAGCACTGCGTACAAAAGGACTCTTCACATCAGAGGGGTACATATGAAGCAGTATCCTCGACGTTGTCCAATGTGTCCGGAGAGATTCAACTCGAATTATAAAAGGACGATTCATTTGCAAGACGTTCATAATCAGTCTACAAGGGTGCATAAGTGTGAGACTTGCGGACGGGCGTTCAACTTGAAGTATCACCTGATTTGCCACACTCGCTCAGTGCATCTTCAGGAGAGGAATCAGCAGTGCGATATATGTCATCAAAGGTTCTGTAACAAGGAGACGCTAAAGAGACATATGGTGATACATACTGGGGAGAAGAATTATAAGTGTGAAGTGTGCGGGATGGCGTTTTTGCGAAGGAAGAACTTGAAAGATCATTTAAGGCTTCACGAAATGGGTTGA
- Protein Sequence
- MSFLFEFHAGLAAGMGADSWAGLCVDMGSEMAYALRVAIRGKLWADFLAGMGIDFWAGLLWVKYTQKSYNALRVQYNNGFRMLLGLPRWCSASEMFAEARTDGFLAVIRNRVASLLHRVRGDDHLPPIVSSETETTEYKPKNSLDPTQLKNLNDELKARKKRATLLLELTRICPFRWTKNLYLCFYCDQQFSDPARLREHHSFEHISQTPAEIRQAISQLKKHELIKVEITDVSCKLCDDYIIDFFELKTHLLVKHKKNVDPKSNDGLLPFKVTKNDFQCAICGDKYVEFKTLNQHMNVHFQNFICEQCGTGFITPDRLRTHAFSHESGSVPCDGCDKVFRSTNAKNEHYANVHMQVKRHRCPHCSETFRNYFQRNKHVSNIHGLKLKEFKCTMCPKVFTLSGKLGVHIRTVHLKVKRHACDHCEWKFYSKSELKEHMIRHGGERKHQCNVCKKAYARKYTLREHMRIHDNDRRFVCTTCGRSFVQNCSLKHHAKIHHRQTVAARTDQKILPDISKRKKVVPLFQVAYDRTLCRPLGTITDFTKLRQRIIPTLAKLSSRSPSPLSICRSPSPLKNDPPETTVVPPRPKQKNPDVRQNALTVFEFSTVYPFIYGNNKFKCFICSQAFLETALLRAHMNEAHTFAPLKRLVNNRRENILKVDVSEIVCKICSAELPGLTELKSHLKTDHNKLVDPELKDNIIPFKLETSDGGYKCVICDEHFIKVRILVIHMSVHFNNYSCEVCGSGFMTLRLLKKHLEVHESGNFPCDRCSKVFSTAYKRTLHIRGVHMKQYPRRCPMCPERFNSNYKRTIHLQDVHNQSTRVHKCETCGRAFNLKYHLICHTRSVHLQERNQQCDICHQRFCNKETLKRHMVIHTGEKNYKCEVCGMAFLRRKNLKDHLRLHEMG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00408647;
- 90% Identity
- -
- 80% Identity
- -