Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 2.7e-05 0.69 11.5 0.0 26 47 16 37 8 42 0.89

2 6 0.014 3.4e+02 2.9 0.2 22 52 67 97 58 98 0.84

3 6 0.0013 34 6.1 0.4 16 43 121 148 109 152 0.74

4 6 0.00013 3.4 9.3 0.2 18 52 151 185 145 187 0.89

5 6 1.8e-05 0.45 12.1 2.4 8 48 197 236 188 240 0.82

6 6 0.026 6.6e+02 2.0 0.2 23 48 268 293 259 296 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	2.7e-05	0.69	11.5	0.0	26	47	16	37	8	42	0.89
2	6	0.014	3.4e+02	2.9	0.2	22	52	67	97	58	98	0.84
3	6	0.0013	34	6.1	0.4	16	43	121	148	109	152	0.74
4	6	0.00013	3.4	9.3	0.2	18	52	151	185	145	187	0.89
5	6	1.8e-05	0.45	12.1	2.4	8	48	197	236	188	240	0.82
6	6	0.026	6.6e+02	2.0	0.2	23	48	268	293	259	296	0.86

Coding Sequence: TCTGAGGAAGTTCTGAGTTTGAACTCGACTGTGGACGGAAAGTACATGTGTCCCATCTGTTACAAACGTTTTACGAGCAAAGGAAATGTACAGAGGCACATGCAACTACACACAAGAGAGAAGCTGGAGTGCAACGTGTGCTTTAGACAGTTTGTTAAGAAATACTTGTACGAGAGACATCTCCTGACGCATTCCACAGAAAAGAGATTCAAATGCGAGGAGTGCCAGAAGAACTTCAGAACGTCGTCTAATTTagaacaacataaaaaaatacaccttGTCATTAAGccttttaaatgtgaaaaatgtTGCCGTCAGTTCGCTGTTAAGGCAAATCTAGTGAAACATCAGAGTACGGGTCGGTGCAAGCGATCTAACGACCAGCCTATAGTATGTACTGTATGTGATAAAGTGTTCAAAAGGGAGTTTCTGTTGAAGAGTCACCAGCGACGCCACACGACCGAGCGTCCCTTTACTTGCGACAAGTGCCACATGAGTTTCAAGTACAAGTCGACGTTGATTCGTCACGTTCAGCTTCACAACGGCATCAAGCCCTACTCTTGTAAAATATGCAGGAAGAGGTTCACTCATGCCGGTCTCATCAAGCCCCACATGAGGAAGCATACTGGAGAGAAACCGTATTCCTGTCccgtttgtaataaaactttcgCTCACAAACACAACATGCAGAGACATACGATACGACACACCAAGATCAAAAACTTAGTGTGTACGGTCTGCAGCAAAACTTTTCCTAAGGAAAGTCGTCTGATATATCACATGCGCACGCACACTAATGCGAAACCGTTTGTATGTGGGGTCTGTGATAAGAAATTCTCCCATCGACAAAACATAATGAGACACTACAGCCGCAAGCATCCCAACGACACCTACGACTGTCGCGACACAGACGCCAGTGTCGCTAAAGATGTATGGGAGAACGTTgttaaaggtaaaataaaaaccgAATATAATGCAAATGGCGGAAATGAATCAGAAATGAGAATAACGCCGGATTGA
Protein Sequence: SEEVLSLNSTVDGKYMCPICYKRFTSKGNVQRHMQLHTREKLECNVCFRQFVKKYLYERHLLTHSTEKRFKCEECQKNFRTSSNLEQHKKIHLVIKPFKCEKCCRQFAVKANLVKHQSTGRCKRSNDQPIVCTVCDKVFKREFLLKSHQRRHTTERPFTCDKCHMSFKYKSTLIRHVQLHNGIKPYSCKICRKRFTHAGLIKPHMRKHTGEKPYSCPVCNKTFAHKHNMQRHTIRHTKIKNLVCTVCSKTFPKESRLIYHMRTHTNAKPFVCGVCDKKFSHRQNIMRHYSRKHPNDTYDCRDTDASVAKDVWENVVKGKIKTEYNANGGNESEMRITPD

Sequence clustering based on sequence similarity using MMseqs2