Mdes002341.1
Basic Information
- Insect
- Mayetiola destructor
- Gene Symbol
- Zfx
- Assembly
- None
- Location
- GL501493.1:2189105-2192117[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 0.011 0.93 10.4 4.0 1 23 198 220 198 220 0.98 2 18 0.017 1.4 9.8 1.4 1 23 226 249 226 249 0.98 3 18 0.018 1.5 9.7 2.3 1 21 254 274 254 278 0.92 4 18 4.3 3.6e+02 2.3 3.3 1 23 309 333 309 333 0.73 5 18 0.00076 0.064 14.1 1.3 1 23 339 362 339 362 0.97 6 18 0.0024 0.2 12.5 2.5 1 23 367 390 367 390 0.95 7 18 0.14 12 6.9 0.1 1 13 408 420 408 420 0.91 8 18 0.045 3.8 8.5 1.6 1 23 419 442 419 442 0.96 9 18 0.00066 0.055 14.3 3.0 1 23 448 470 448 470 0.98 10 18 0.018 1.5 9.7 2.0 1 23 478 500 478 500 0.98 11 18 0.0053 0.44 11.4 3.0 1 23 505 528 505 528 0.92 12 18 0.0015 0.12 13.1 2.2 1 20 535 554 535 558 0.94 13 18 0.00025 0.021 15.6 0.9 3 23 568 588 566 588 0.95 14 18 0.00067 0.056 14.2 0.7 2 23 595 616 594 616 0.96 15 18 0.00011 0.009 16.7 0.3 5 23 633 651 622 651 0.81 16 18 0.0012 0.1 13.4 2.1 1 23 659 681 659 681 0.98 17 18 1.5e-06 0.00013 22.6 1.4 1 23 687 709 687 709 0.99 18 18 0.00047 0.04 14.7 2.4 1 23 715 737 715 737 0.97
Sequence Information
- Coding Sequence
- ATGGATGAAAGTAATTCCATTCGGAATTATTGTCGAATTTGTGCAACAAATCCACCAGATGTTCGCAACATTTTCGAAGTGGTTTACAAAGAAAAATTGCTTTCGGATATATTGGGACAGTGTTTGCAATGCACAATATTCCGAACCGAATATTTACCCGAATACATTTGTTCGCAATGCTGTGCAGATTTGATTAAAATGCACAAATTCATTGTAAACTATGAAAAAAGTGAAAAATGGTTCATTTCGCGTTATAATGCAATCAATGAGGCTAGAACAATCAAAATCGAAACCGAGCGTCCCATAGAATTGGAACGAATCCCGGAAATTTTGGTCGCACCGAAAATTCGAGTATTTACCGAGAGTCTTCAAAATTCATCACCGTATGCATTGGAATCAAAAGGAGAATATGATTGCGATTATGAATTTGAAGGGGCTGAATTGTCAGCCAGTCCGAATGGATCCAGTTCCGAGATGCAAGAACTGAACGAAGCAAATTGTTATGAATCAGGTGGTAACAACGAAAACACTATAAAGAGAGTGAATATTCATAAAAAGAAAACAATTCGTCGCGAGGAAGAAACTGGGCAATATCAGTGTTCCATATGCGCTAAACAATTTTCGTGTTTGAATAATTTAAGAAAGCATAAAAATTTGCATACTGGAAGTAAAATGTTCAAATGTTACTTTTGTGACCTTCAAGTGAAAAGAAGCGATTATAGAGTAAATCACATCCGTAGAGCCCATCCCGAAGTCGTCTTTGAATGCTGGCTGTGCCGAAATAAATTCAACACATTTTATGATCTTTGTAATCATATGCTTGAGGGTTCTCATAGTAGTTTGCCTGAAAATGAATCGAATGCGGTAGCGAGCGTCTCCGGAGAAATAAAGAGAATTCGCAAAAAACCGGCATCACAACAACAGTATCAATGCAGCCAGTCTTCTTGTTCGAAACGATTCTTGACTTTACACCGTTTAAAATTGCATGAAAATTTGCATACCGGCGAAAAACTTTTCAACTGCTTTTTTTGTGACGAAACGTTCGCACGTTCTGATTATCGAGTGAGACACGTCCGTAAAGTGCATCCCGAAGTTGTGTTTGAATGCTATGTGTGCAAAGCTACATTTAATCAATATTTTACCTTATGTCAACATATGCTGGAAGTTCATTACCAGAAAATAGATCGAGAAGCCGGAAATAGATCGAGAACTTGCCAAAAATATATTTGTGAGGTATGTGGAATGTCTTTTGTGCATCAATGCAAATATTGCGAATTGAAGCTCACATCTCGTGAAGGAAAAAAAAAACATGAACGAAACATTCACGAAGCACCAAAATCATATGAATGCTACCATTGCAAGATGGTTTTTAAGCTATATTTGGATTTAAGCCGTCACATGAAAATCCATTCAACGAATGGCCGCATAACATTTGAGTGTAATTATTGTAAGAGACTTTTTTGGTCCGAACCCAATTATATCAAACACAAACGGAAACATAATACGAAAATTTTCGATTGTGAATATTGTAATGAATCATTCGAAAAACGATTCGATTTGCATTCACATGTTCATGAGGTGCATTACGCCAATTTGAAGCAACATCAATGCGATCAATGCCCACGACATTTCCCATTGAAGTCAACATTGAAGACACATATTTGGAAAATACATACAAAAGAAAAACAAGAAAATCATCTTTGTACAGAATGTGGGAAAACATTTTCGGCCCAGAGTATCTTAAAACAACATTTGCTAGTCCATAGTGACGAAAGACCCATTAGCTGCACTCAGTGTCCATCTAAATTTAAATACACGAGTCAATTGAAAGGTCACATGCTAGTTCATATATCCGAACCAAATTATATCTGTAAAGTAGTGGTCGATGGTGGGCAAATTTGTGGCCGAAAATTTCGATATTCTTACAGCCTAAATTTACATCGAAAAAGACATAGCAATTTACATCGAAAAAGATTTCAGTGTTCCAGCTGCCCTTCGAAATTTTTCAGCAAAGAAAAACTGAAGGTGCATACACGAATACACACGGGTGAACGTCCCTATAAATGTGACTACTGTTTTCGTGCTTTTACTCAAAAGGGTGATATGACAAAACACATGCTAATCCATTTGGGTCCAACGCCACATAAATGTACCAATTGTGGAGAAGCATTTCGATTGGAAACTGAACTTCGCAAACATTCCTATACACATTTTAAGCCAACCGAAAATTAA
- Protein Sequence
- MDESNSIRNYCRICATNPPDVRNIFEVVYKEKLLSDILGQCLQCTIFRTEYLPEYICSQCCADLIKMHKFIVNYEKSEKWFISRYNAINEARTIKIETERPIELERIPEILVAPKIRVFTESLQNSSPYALESKGEYDCDYEFEGAELSASPNGSSSEMQELNEANCYESGGNNENTIKRVNIHKKKTIRREEETGQYQCSICAKQFSCLNNLRKHKNLHTGSKMFKCYFCDLQVKRSDYRVNHIRRAHPEVVFECWLCRNKFNTFYDLCNHMLEGSHSSLPENESNAVASVSGEIKRIRKKPASQQQYQCSQSSCSKRFLTLHRLKLHENLHTGEKLFNCFFCDETFARSDYRVRHVRKVHPEVVFECYVCKATFNQYFTLCQHMLEVHYQKIDREAGNRSRTCQKYICEVCGMSFVHQCKYCELKLTSREGKKKHERNIHEAPKSYECYHCKMVFKLYLDLSRHMKIHSTNGRITFECNYCKRLFWSEPNYIKHKRKHNTKIFDCEYCNESFEKRFDLHSHVHEVHYANLKQHQCDQCPRHFPLKSTLKTHIWKIHTKEKQENHLCTECGKTFSAQSILKQHLLVHSDERPISCTQCPSKFKYTSQLKGHMLVHISEPNYICKVVVDGGQICGRKFRYSYSLNLHRKRHSNLHRKRFQCSSCPSKFFSKEKLKVHTRIHTGERPYKCDYCFRAFTQKGDMTKHMLIHLGPTPHKCTNCGEAFRLETELRKHSYTHFKPTEN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00957362;
- 90% Identity
- -
- 80% Identity
- -