Basic Information

Insect: Mantis religiosa
Gene Symbol: foxp1
Assembly: GCA_030765055.1
Location: CM060948.1:38835043-38863513[-]

Transcription Factor Domain

TF Family: Fork_head
Domain: Fork_head domain
PFAM: PF00250
TF Group: Helix-turn-helix
Description: The fork head domain is a conserved DNA-binding domain (also known as a winged helix) of about 100 amino-acid residues. Drosophila melanogaster fork head protein is a transcription factor that promotes terminal rather than segmental development, contains neither homeodomains nor zinc-fingers characteristic of other transcription factors [1]. Instead, it contains a distinct type of DNA-binding region, containing around 100 amino acids, which has since been identified in a number of transcription factors (including D. melanogaster FD1-5, mammalian HNF-3, human HTLF, Saccharomyces cerevisiae HCM1, etc.). This is referred to as the fork head domain but is also known as a 'winged helix' [1, 2, 3]. The fork head domain binds B-DNA as a monomer [2], but shows no similarity to previously identified DNA-binding motifs. Although the domain is found in several different transcription factors, a common function is their involvement in early developmental decisions of cell fates during embryogenesis [3].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 2 4.6e-30 2.4e-26 94.0 0.3 2 81 275 348 274 355 0.94

2 2 2.8e-06 0.015 17.7 0.0 48 82 374 403 360 409 0.82

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	2	4.6e-30	2.4e-26	94.0	0.3	2	81	275	348	274	355	0.94
2	2	2.8e-06	0.015	17.7	0.0	48	82	374	403	360	409	0.82

Sequence Information

Coding Sequence: ATGTCGTCCATAGGCTTGCCACCTGCAGATATCCCCAGTCCGTGGAAAGAATCTCCTAGTGAAGGCCTCGAACCACACCATAATCCACCTCCTCACAAAGGAATCACGGGTCTGAATGGACTTCTAAGTTCCATGGGACTGGGTCGTAGAGAAGGCGGCCTCAATGGTGTCGCAGGAGTGCAAGACGACAAGCTTATGGATGGTTGTGGTGGCGACAAAATGCACCCCCTCTACGGCCATGGTGTTTGCAAATGGCCTGGCTGTGAACTCATCTGCGAAGATTTCCAATCATTCCTCAAgCATCTAAATACAGAACATACATTAGATGACAGGTCTACAGCACAGGCTCGTGTTCAAATGCAAGTAGTTTCTCAGTTAGAACTGCAGCTACAGAAAGAAAGGGATCGATTGCAGGCAATGATGCATCATTTACACATGTCTAAACAGCAAGCATCCCCAGAACCACCGAAAGCTGACACAGCGTCCGATCTCTTTCAAACAGGCCCAGGTCTTACAAAACTAAGTCTCTCATCTGTCCTTCTAAGTCAGCCTCCACCCAGCTTAGCCACATCTGCTGTAAGTCAAGTGGCACCTGTATCCATGTCAGCATTAGTATCTGCAGTTCGTTCACCAATACTGCAGCCCCCAACACCTAACATGGGTGGACCAATCAGAAGACGCATAAGTGATAAATCTGCTTTATCTCTTGCCGGAGGAGCTTTTGAAGATACCCCATTAAGACGGCGTGTTGCAGAAAGAGGTGCACTAGATATTTCTGAAGAAATTCAGAGGAATAGGGAGTTTTATAAGAACGCTGATGTGAGACCTCCTTTCACTTATGCCTCACTAATTCGCCAGTCCATCATTGAATCACCTGACAAGCAGCTAACCCTAAATGAAATCTACAACTGGTTCCAGAATACGTTCTGCTACTTCCGGAGAAATGCAGCAACATGGAAGAATGCAGTGCGACACAACCTGTCTCTACACAAATGTTTCATGAGGGTGGAGAACGTCAAAGGCGCAGTATGGACTGTGGATGAAGTGGAATTTTACAAGCGTCGACCCCAACGGTGCACCACCGGGTATGTCACTTCGGAACCGAGCCGGACACGCAAGTTGAACGCGATCCGCACCAATCTGTCACTGCACAAGTGTTTTGTGCGCTATGAAGACGACTTTGGCTCCTTCTGGATGGTGGACGATGCAGAGTTTGTCAAGCGACGCCATCTTTCTCGTGGTCGTCCCCGGAAATATGACCCCACCCCATCACCCACTCCACCCCACCTCTCCGCACAGTAA
Protein Sequence: MSSIGLPPADIPSPWKESPSEGLEPHHNPPPHKGITGLNGLLSSMGLGRREGGLNGVAGVQDDKLMDGCGGDKMHPLYGHGVCKWPGCELICEDFQSFLKHLNTEHTLDDRSTAQARVQMQVVSQLELQLQKERDRLQAMMHHLHMSKQQASPEPPKADTASDLFQTGPGLTKLSLSSVLLSQPPPSLATSAVSQVAPVSMSALVSAVRSPILQPPTPNMGGPIRRRISDKSALSLAGGAFEDTPLRRRVAERGALDISEEIQRNREFYKNADVRPPFTYASLIRQSIIESPDKQLTLNEIYNWFQNTFCYFRRNAATWKNAVRHNLSLHKCFMRVENVKGAVWTVDEVEFYKRRPQRCTTGYVTSEPSRTRKLNAIRTNLSLHKCFVRYEDDFGSFWMVDDAEFVKRRHLSRGRPRKYDPTPSPTPPHLSAQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01410585;
90% Identity: iTF_01410585;
80% Identity: -