Mjur007224.1
Basic Information
- Insect
- Maniola jurtina
- Gene Symbol
- sem-4
- Assembly
- GCA_905333055.1
- Location
- HG995233.1:7464306-7476922[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.14 6.4 7.8 0.5 3 23 142 162 140 162 0.96 2 13 0.0034 0.16 12.9 2.8 1 23 480 502 480 502 0.99 3 13 0.00033 0.015 16.1 1.0 1 23 508 531 508 531 0.96 4 13 0.03 1.4 9.9 4.8 1 23 536 559 536 559 0.94 5 13 4.4e-07 2e-05 25.1 0.6 2 23 718 739 717 739 0.98 6 13 0.00099 0.046 14.6 2.7 1 23 745 767 745 767 0.98 7 13 0.0081 0.38 11.7 1.3 1 23 891 913 891 913 0.95 8 13 0.0005 0.023 15.5 1.9 1 23 919 941 919 941 0.96 9 13 0.016 0.73 10.8 4.1 1 23 950 972 950 972 0.98 10 13 0.00024 0.011 16.5 0.6 2 23 1019 1040 1019 1040 0.97 11 13 0.0078 0.36 11.8 4.4 1 23 1057 1079 1057 1079 0.96 12 13 2.8e-06 0.00013 22.6 0.5 1 23 1085 1107 1085 1107 0.98 13 13 1.8e-06 8.4e-05 23.2 3.1 1 23 1113 1136 1113 1136 0.98
Sequence Information
- Coding Sequence
- ATGAATAATCCAATTGCACCAGATCTTGACCCTCTAAGCTCCTATAATTTGAACAACTATCCGAATTTGGAAAGCTTCGGAAATCCGCTGCTACCTTTCGGAAATCAGTATCCATATTCCGTTAAACTAGAGAATTACCAGAATCCAAATTATTACAATCTACCGCAAGGAATACCACCTAACTTTACACAAGATACTTCAGAAAATACTAGTGTAAATGCAACTTTGGAAGAAACCGGTAATGAAACACAAACAGTCACGGATCAAGATCAAAATAACGAATACCCAAATAACATAGATGTCGCAGAAGAACAGGATATTAAACCAGATATTAGTAAATTGCTAAATAATAGAAAAATTAAAAAGGAGCGTAGCAAATACTTCTCAGAAAAGATCACGGAAAAGGATTTTAAATTTTATGGATGTTCCGTATGCAATATCAATTTCAAGGAACTGCACGAGTTAGACAACCATGTGACAATACATAAGGATAGGCTCACCAGCTATGATTGGAGAGTGAAGAGTCAGATAATGAAGAAGAAGATGAAGAAAGAGTTGAAGAAGAATAAGAAGTTGAAGAAGAAAGTCAAAGCAGAACCTGAAATGGAGTTTAATATAGAAATTAAACCAGAGGAGGGATATATAGGTAACGAAATAGCATCAGACTTTGTTAACAATACAGAATCAGACAACCAGAGTTTTAAGGAAAACAACACGGAGGAAACTGACAACAAAGAGACAAAAACAATGGAATCCAGCAATGCAAACTACAAGCAAGAATTGGACAAAGAGGTAAATGCAATGGAATCCAACACTACAAACAACAAGAAAAAATTGGACAAAGAAACTAAAACAATGGAAACTAACAATGCAAACAACAATCAAGAATTTAACCAAGAGACAAATGCAATGGAATCCAACACTACAAACAACAAGCAAGAATTGAACCAAGAGATAAATGCAATGGAATTCAATACTACAAATGACAAGCAAGAATTGAACCAAGAGATAAATCCAATGGAATCCAACACTTCAAACAACAAGCAAGAATTGAACCAAGAGATTAAAACAATGGAATCTATCAATGCGAACAATAAACAAGAATTGAATCAAGAGACAAATACAATGGAACCTATCAATGCGAACAATAAACTAGAATTGAATCAAGAGACAAATACAATGGAACCTATCAATGCAAACAATAAACAAGAATTGAACCAAGAGATAAATGCAATGGAATCCAACACTACAAACAATAAGCAAGAAATTAATCAAGAGATAAAAGTAATGGAACCTAGCAATGCAAACAATAAACAAGAATTGAACCAAGAAATAAAGGCAATGGAAATCTACAAGCGTAATATGTACAAAGATACAAAAATAATGGAACCTATCAATGCGGCCAACAAGCAGGAATTGTTGAACTTGCAAAAGATATATAAATGTTTTGCCTGTCAGAAACAGTTCACACTGAGTTACTATTTGAAACTACATGTCAGATCTCATACAGATGAAAAACCTTATACATGCGTCCAGTGCGGCCAATCCTTCATCACAGCAAGTAAACTGGGACGACACAATAAAAGATTCCATCTCGCCATCCGCTACCAGTGCAGGATATGCTATAGATTCTTTTCTAGATTTGAATTCTTAACTCGACATTTCGACAAAAAACACCCAGATGACAAGTTAGAAGGAGAACCCTATGATTTCAATGCTATACTACCTTACCTAAAAGAGTTAGAGGAACAACTCCGCGAGAAAACAGAAATGGAGAAAGCCGCAAAAAAACCAGATCCCTGGTCCTTTGAAGTTGAAACCAAAACTGAACTCAATGAAGTGAAGGAGGAGTCCCAAGACGACACAACAGATGGACGGATAACGGTTACCATAGAGCAAGTCAAAGTTGACATGGACGGAGTGGAGGTGAAGATTGAAGAGTTGGATGTGAAAGGGGATATTCATGGTGATGATGATGATAATCGGGATGATATTGATGAGGATGGATTTGGTGATGTGAAAGATGAAAGTACTCATATGAAGGATGAGAATCTCTCAGATGATGATTATTTCCCTTCAAACACCTGGGCATCAAAACCAGCCATGGAAGACCCTCCATCTCCAAAGAGACTCAAATTGGAGGACCGAGTGAAATGCCCAATCTGCGAGAAGAAATTCAGCTCAGCCTCCTACATGAGGATCCACATGCGGACCCATACTGGAGAAAAGCCGTTCAAATGCTACATATGCAACATGGGCTTCATCACCTCCAGTAAAATGCATCGTCATGTGTTGACTCATCCTGAATCCTGGGCAGATGATGACGTCAAGGAGGAAAAAGATAGTAAAGAAGGAATAAACATCAAAACTGAAGAAGGAGAGAATACGGAAGAAGACAAGAAAGCTATAAAAAAGTTAAGAATGAAAAAATATCTAGCCAGACTCAACAAGAAATCTAAACCTTCGGACAAGAAGAAGCGGCTCAATCAGAAGAGACCATTCGCTTGCGAATTTTGCCAGAAAAGATTCCTACATGTCGAGACTTTGCAGGTCCACAAGAAGTGCCACGAGGGTGAGAGCCTGGTGTTCAAGTGCAACTTTTGCCTCGCGGAGCACCCCGACGATGTCACTCGGAAGGCGCACGAGGCCTCGCACCAGGGCCCCAAGCCCTACCTTTGCACCATATGCGGACGCGGATACAAGAAACGGGAAACCATGATATACCACCGCAAGAACCACAAGCCGGACCGCGAGTTCATATGTGACATCTGCACCAAGAGTTTCAATGCGCAGTGCAAGCTGCAGAGACATATAGTCAGCCATCGCACGCAACGGTTCGTGCTGCGCTACGAGTGCCCGGTGTGCGCGCACATGTTCCACACCAAGTACCACGTGCAGATGCACCTCGCCACGCACCAGAAGGAGGGCCTAATTCAAGAGGAAAACCGCAGCGAAATCCTAGCGATGGTTCTGCAGAACGCTCGGAAGATACCCAAAAGCGCAGACGCGCCCCCCACCCTCACCGACATCGTGCCCAGCGACGAGCGCAGCCGCGTGTGCAACATATGCGGGGAGGTGTTCCAACACTTCTACTATCTGGAAGAACACCTAAAGAGTCACGGTTCGAAAATAGCCATAGAAGACAGCGAGAAAAGCGAGGAGAAGAAACATGTATGCCCCATTTGCAACAAAGGATTCAAGCTACACTACTACTTAAAACTTCACAGTTTCACACACACTAAAGAAAAACCTTTCATTTGCCAGCAGTGTGGAAAGGGCTTTATAACTCGGGGCAAACTAAAACGTCACATAGAAACCCATACGGGCTTGAAAAAGTACCAATGTCATGTTTGCTATAAGTTTTTCACCAGACCTAGTTACTTAAGGATCCATGTTAGAACTATTCACGGCACTCAAGACTATAATTTTAGGATGGAAAAGTCTTATAGCAACTTCGGCGCCGACTACACGCCTTAA
- Protein Sequence
- MNNPIAPDLDPLSSYNLNNYPNLESFGNPLLPFGNQYPYSVKLENYQNPNYYNLPQGIPPNFTQDTSENTSVNATLEETGNETQTVTDQDQNNEYPNNIDVAEEQDIKPDISKLLNNRKIKKERSKYFSEKITEKDFKFYGCSVCNINFKELHELDNHVTIHKDRLTSYDWRVKSQIMKKKMKKELKKNKKLKKKVKAEPEMEFNIEIKPEEGYIGNEIASDFVNNTESDNQSFKENNTEETDNKETKTMESSNANYKQELDKEVNAMESNTTNNKKKLDKETKTMETNNANNNQEFNQETNAMESNTTNNKQELNQEINAMEFNTTNDKQELNQEINPMESNTSNNKQELNQEIKTMESINANNKQELNQETNTMEPINANNKLELNQETNTMEPINANNKQELNQEINAMESNTTNNKQEINQEIKVMEPSNANNKQELNQEIKAMEIYKRNMYKDTKIMEPINAANKQELLNLQKIYKCFACQKQFTLSYYLKLHVRSHTDEKPYTCVQCGQSFITASKLGRHNKRFHLAIRYQCRICYRFFSRFEFLTRHFDKKHPDDKLEGEPYDFNAILPYLKELEEQLREKTEMEKAAKKPDPWSFEVETKTELNEVKEESQDDTTDGRITVTIEQVKVDMDGVEVKIEELDVKGDIHGDDDDNRDDIDEDGFGDVKDESTHMKDENLSDDDYFPSNTWASKPAMEDPPSPKRLKLEDRVKCPICEKKFSSASYMRIHMRTHTGEKPFKCYICNMGFITSSKMHRHVLTHPESWADDDVKEEKDSKEGINIKTEEGENTEEDKKAIKKLRMKKYLARLNKKSKPSDKKKRLNQKRPFACEFCQKRFLHVETLQVHKKCHEGESLVFKCNFCLAEHPDDVTRKAHEASHQGPKPYLCTICGRGYKKRETMIYHRKNHKPDREFICDICTKSFNAQCKLQRHIVSHRTQRFVLRYECPVCAHMFHTKYHVQMHLATHQKEGLIQEENRSEILAMVLQNARKIPKSADAPPTLTDIVPSDERSRVCNICGEVFQHFYYLEEHLKSHGSKIAIEDSEKSEEKKHVCPICNKGFKLHYYLKLHSFTHTKEKPFICQQCGKGFITRGKLKRHIETHTGLKKYQCHVCYKFFTRPSYLRIHVRTIHGTQDYNFRMEKSYSNFGADYTP
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00953766;
- 90% Identity
- -
- 80% Identity
- -