Basic Information

Transcription Factor Domain

TF Family: IRF
Domain: IRF domain
PFAM: PF00605
TF Group: Helix-turn-helix
Description: This family of transcription factors are important in the regulation of interferons in response to infection by virus and in the regulation of interferon-inducible genes. Three of the five conserved tryptophan residues bind to DNA.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.077 2.1e+03 -0.4 0.0 25 39 93 107 88 112 0.81

2 6 0.0028 76 4.3 0.0 12 39 105 132 99 137 0.83

3 6 0.0044 1.2e+02 3.6 0.0 14 39 132 157 129 162 0.84

4 6 0.0035 95 4.0 0.0 13 39 156 182 151 186 0.84

5 6 0.0037 1e+02 3.9 0.0 13 39 181 207 176 210 0.83

6 6 0.0034 92 4.0 0.0 14 40 207 233 203 242 0.84

#	of	c-Evalue	i-Evalue	score	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.077	2.1e+03	-0.4	25	39	93	107	88	112	0.81
2	6	0.0028	76	4.3	12	39	105	132	99	137	0.83
3	6	0.0044	1.2e+02	3.6	14	39	132	157	129	162	0.84
4	6	0.0035	95	4.0	13	39	156	182	151	186	0.84
5	6	0.0037	1e+02	3.9	13	39	181	207	176	210	0.83
6	6	0.0034	92	4.0	14	40	207	233	203	242	0.84

Coding Sequence: ATGGGGGTTGCTTCTAGTAAAACTAAACCAGTCGAATTTGTTAACCATTGTCAATTAGAGCTATCTGAGCATGAACTTTTGGAACATCTCATAAAAGAACAATACAAACTTGATTCACTAGGTATTTCTAAGCGTGAAACTCTTCACAGTAAACAAGATTTGCGTGCTATTGGGGATTTTAGACTCTACCACTTCACGTTTACCAACTGTGTGCACCCGCTGAACATAATACAAAACGACGCGGCGCATCTCTATCTACGGGGCGACTCACCTGGCAACACTGCGCTACGAGTCACCTGGCAACACTGCGCTACGAGTCACCTGGCAACACTGCGCTACGAGTCACCTGGCAACACTGCGCTACGAGTCACCTGGCAACACTGCGCTACGAGTCACCTGGCAACACTGCGCTACGAGTCACCTGGCAACACTGCGCTACGAGTCACCTGGCAACACTGCGCTACGAGTCACCTGGCAACACTGCGCTACGAGTCACCTGGCAACACTGCGCTACGAGTCACCTGGCAACACTGCGCTACGAGTCACCTGGCAACACTGCGCTACGAGTCACCTGGCAACACTGCGCTACGAGTCACCTGGCAACACTGCGCTACGAGTCACCTGGCAACACTGCGCTACGAGTCACCTGGCAACACTGCGCTACGAGTCACCTGGCAACACTGCGCTACGAGTCACCTGGCAACACTGCGCGCCGCCCGTCATAGACAATATCCGTATCCAAAGAATCGACGCAAGCGTCCGTCATGTGAATAA
Protein Sequence: MGVASSKTKPVEFVNHCQLELSEHELLEHLIKEQYKLDSLGISKRETLHSKQDLRAIGDFRLYHFTFTNCVHPLNIIQNDAAHLYLRGDSPGNTALRVTWQHCATSHLATLRYESPGNTALRVTWQHCATSHLATLRYESPGNTALRVTWQHCATSHLATLRYESPGNTALRVTWQHCATSHLATLRYESPGNTALRVTWQHCATSHLATLRYESPGNTALRVTWQHCATSHLATLRAARHRQYPYPKNRRKRPSCE

Sequence clustering based on sequence similarity using MMseqs2