IRF
- Domain
- IRF domain
- Group
- Helix-turn-helix
- PFAM
- PF00605
- Desciption
- This family of transcription factors are important in the regulation of interferons in response to infection by virus and in the regulation of interferon-inducible genes. Three of the five conserved tryptophan residues bind to DNA.
- Rederence
-
- Structure of IRF-1 with bound DNA reveals determinants of interferon regulation. Escalante CR, Yie J, Thanos D, Aggarwal AK. Nature 391, 103-6, (1998).
Statistic of Transcription Factors
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Transcription Factor Table
Gene ID | Insect | Gene Name | Gene Symbol |
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