IRF


Domain
IRF domain
Group
Helix-turn-helix
PFAM
PF00605
Desciption
This family of transcription factors are important in the regulation of interferons in response to infection by virus and in the regulation of interferon-inducible genes. Three of the five conserved tryptophan residues bind to DNA.
Rederence
  • Structure of IRF-1 with bound DNA reveals determinants of interferon regulation. Escalante CR, Yie J, Thanos D, Aggarwal AK. Nature 391, 103-6, (1998).

Statistic of Transcription Factors




Transcription Factor Table

Species


Gene ID Insect Gene Name Gene Symbol