Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.003 74 4.0 0.2 12 43 109 141 106 147 0.70

2 5 0.022 5.6e+02 1.2 0.0 22 45 149 172 143 179 0.82

3 5 0.00032 8.1 7.1 0.1 22 45 177 200 170 203 0.88

4 5 1e-05 0.26 11.9 0.1 21 52 204 235 200 235 0.88

5 5 0.00028 7.2 7.3 0.0 21 48 232 259 228 262 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.003	74	4.0	0.2	12	43	109	141	106	147	0.70
2	5	0.022	5.6e+02	1.2	0.0	22	45	149	172	143	179	0.82
3	5	0.00032	8.1	7.1	0.1	22	45	177	200	170	203	0.88
4	5	1e-05	0.26	11.9	0.1	21	52	204	235	200	235	0.88
5	5	0.00028	7.2	7.3	0.0	21	48	232	259	228	262	0.90

Coding Sequence: ATGGAAAATGAAGACCACGAAGTAGATTTTCATTCATCATTAGAGCCCGATGTGATTATAGATGATCATTCGggAGATCGTTATTTCTCAGACAATCCTTTAGGACCAAATCATGACTATAGAAACAATATACCGGACGCTGCTGGTCCAGAAATTTCACTTATACCGGTTAGAAGAAATtcactgaaaataaaaatgtacgaCAAAATATTATGTAAAGATGGTTCGTTGGATATGCAAGTTCCAAAAGTGCAAAGAATTATTCAAAGATCTCCTCGCCAAAATGTAAGACTGATATCACACGAAGAAATGGTACAAGCAGAAACTGAATGTGTACACTCGAAACGTAAATCCTTACCTTTGGAAAAATGTCCaatttgtaaaaagttttttcgTCGCATGAAAACGCATTTACAAAAACACGAGAATGTTAATAGGGATCCTAACGATCCACTAACATGTCGATTTTGTCGAAAAAGTTTTAATACCGGAAGTAATTTAAGTATACATATGCGAACGCATACAGGTGATAAACCGTATATTTGTGAAATTTGTACAAAAGGTTTTGCACAATCTTGTAATTTAATAAACCATATGCGTATTCATACAGGTGAGAGGCCTTTTAAATGTCCTCATTGTGATCGTGCTTTTACACAATCgggtaatttaaataatcacgTTAGGTTACACACCGACGAGAAACCATTTAAATGCCATTTTTGTGACAAAGCATTTACTCAATCGGGCAATCTTAATTCTCATATAAGAAACAATCACAAAGTTATGACTAATGGCGAAAACGAACTGAATCAAGTTCagtaa
Protein Sequence: MENEDHEVDFHSSLEPDVIIDDHSGDRYFSDNPLGPNHDYRNNIPDAAGPEISLIPVRRNSLKIKMYDKILCKDGSLDMQVPKVQRIIQRSPRQNVRLISHEEMVQAETECVHSKRKSLPLEKCPICKKFFRRMKTHLQKHENVNRDPNDPLTCRFCRKSFNTGSNLSIHMRTHTGDKPYICEICTKGFAQSCNLINHMRIHTGERPFKCPHCDRAFTQSGNLNNHVRLHTDEKPFKCHFCDKAFTQSGNLNSHIRNNHKVMTNGENELNQVQ

Sequence clustering based on sequence similarity using MMseqs2