Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.0021 42 4.5 0.1 12 43 109 141 106 146 0.72

2 5 0.024 4.9e+02 1.1 0.0 22 45 149 172 145 179 0.81

3 5 0.00035 7.2 7.0 0.1 22 45 177 200 172 203 0.88

4 5 1.1e-05 0.24 11.8 0.1 21 52 204 235 202 235 0.88

5 5 0.00033 6.7 7.1 0.0 21 48 232 259 229 261 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.0021	42	4.5	0.1	12	43	109	141	106	146	0.72
2	5	0.024	4.9e+02	1.1	0.0	22	45	149	172	145	179	0.81
3	5	0.00035	7.2	7.0	0.1	22	45	177	200	172	203	0.88
4	5	1.1e-05	0.24	11.8	0.1	21	52	204	235	202	235	0.88
5	5	0.00033	6.7	7.1	0.0	21	48	232	259	229	261	0.90

Coding Sequence: ATGGAAAATGATGATCACGAAGTAGATTTTCATTCGTCATTAGAACCAGACGTGATTATAGACGATAATTCGgGAGAACGTTATTTCTCGGACAATCCTTTAGGACCAAATCATGATTATAGAAATGGTATACCAGAACCTGCCGGCCCAGAAATTTCCCTTATACCGGTCCGAAGAAATtcgcttaaaataaaaatgtacgacaaaatattatgtaaagaCGATTCGTTAAATAtgcaagtttcaaaaattcaaagaaTGGTTCAAAGATCACCTCGTCAAAATGTAAGACTGATATCTCACGAAGAAATGTTACAAGCAGAAACAGAAAGCGTACATTCAAAACGTAAATCTTTACCATTGGAAAAATGCCCCAtctgtaaaaagttttttcgtcGTATGAAGACACACTTACAGAAACACGAGGACGTCAATAGAGATCCCAACGATCCGCTAACGTGTCGATTTTGcagaaaaagtttcaataCCGGAAGTAATTTAAGTATACACATGCGAACTCACACGGGCGATAAACCGTACATTTGCGAAATTTGCACGAAAGGTTTTGCACAatcttgtaatttaataaaccaCATGCGTATTCATACGGGCGAGAGGCCTTTTAAGTGTCCTCATTGCGATCGCGCTTTTACACAGTCtggcaatttaaataatcacgTGAGGTTACACACCGacgaaaaaccatttaaatgcCATTTTTGTGACAAGGCGTTTACTCAATCTGGCAATCTTAACTCGCATATAAGAAACAATcataaaataatgaataacTTGGAAAACGAGCCGAACCAAGTTATTcaataa
Protein Sequence: MENDDHEVDFHSSLEPDVIIDDNSGERYFSDNPLGPNHDYRNGIPEPAGPEISLIPVRRNSLKIKMYDKILCKDDSLNMQVSKIQRMVQRSPRQNVRLISHEEMLQAETESVHSKRKSLPLEKCPICKKFFRRMKTHLQKHEDVNRDPNDPLTCRFCRKSFNTGSNLSIHMRTHTGDKPYICEICTKGFAQSCNLINHMRIHTGERPFKCPHCDRAFTQSGNLNNHVRLHTDEKPFKCHFCDKAFTQSGNLNSHIRNNHKIMNNLENEPNQVIQ

Sequence clustering based on sequence similarity using MMseqs2