Basic Information

Insect: Malthinus flaveolus
Gene Symbol: Znf423_1
Assembly: GCA_950108345.1
Location: OX467290.1:7443001-7451219[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 21 2.5e-06 0.00017 22.1 0.5 1 23 85 107 85 107 0.97

2 21 0.01 0.71 10.6 5.0 1 23 113 135 113 135 0.98

3 21 1.8e-06 0.00012 22.5 5.3 1 23 141 163 141 163 0.99

4 21 9.4e-05 0.0064 17.1 0.3 1 23 169 191 169 191 0.98

5 21 0.028 1.9 9.3 1.0 2 23 204 226 203 226 0.96

6 21 0.001 0.071 13.8 0.4 2 23 247 269 246 269 0.96

7 21 0.33 23 5.9 0.2 1 20 306 325 306 326 0.94

8 21 0.0053 0.36 11.6 0.0 1 23 418 440 418 440 0.97

9 21 0.00014 0.0095 16.5 0.0 2 23 455 476 455 476 0.94

10 21 1.2 79 4.2 1.9 3 23 486 508 484 508 0.81

11 21 0.36 25 5.8 2.7 1 23 513 536 513 536 0.96

12 21 0.081 5.5 7.8 1.8 2 23 601 623 600 623 0.95

13 21 0.00034 0.023 15.3 4.4 2 23 710 731 709 731 0.97

14 21 0.0023 0.16 12.7 0.4 1 23 740 762 740 762 0.97

15 21 0.019 1.3 9.8 1.0 2 23 770 791 770 791 0.96

16 21 0.49 34 5.4 0.1 1 13 837 849 837 852 0.87

17 21 0.0005 0.034 14.8 0.8 1 23 900 922 900 922 0.98

18 21 0.15 10 7.0 0.2 2 23 931 952 931 952 0.95

19 21 0.00092 0.062 14.0 0.3 1 23 960 982 960 982 0.97

20 21 0.34 23 5.9 2.1 1 23 989 1011 989 1011 0.94

21 21 0.15 10 7.0 0.2 2 21 1042 1060 1041 1061 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	21	2.5e-06	0.00017	22.1	0.5	1	23	85	107	85	107	0.97
2	21	0.01	0.71	10.6	5.0	1	23	113	135	113	135	0.98
3	21	1.8e-06	0.00012	22.5	5.3	1	23	141	163	141	163	0.99
4	21	9.4e-05	0.0064	17.1	0.3	1	23	169	191	169	191	0.98
5	21	0.028	1.9	9.3	1.0	2	23	204	226	203	226	0.96
6	21	0.001	0.071	13.8	0.4	2	23	247	269	246	269	0.96
7	21	0.33	23	5.9	0.2	1	20	306	325	306	326	0.94
8	21	0.0053	0.36	11.6	0.0	1	23	418	440	418	440	0.97
9	21	0.00014	0.0095	16.5	0.0	2	23	455	476	455	476	0.94
10	21	1.2	79	4.2	1.9	3	23	486	508	484	508	0.81
11	21	0.36	25	5.8	2.7	1	23	513	536	513	536	0.96
12	21	0.081	5.5	7.8	1.8	2	23	601	623	600	623	0.95
13	21	0.00034	0.023	15.3	4.4	2	23	710	731	709	731	0.97
14	21	0.0023	0.16	12.7	0.4	1	23	740	762	740	762	0.97
15	21	0.019	1.3	9.8	1.0	2	23	770	791	770	791	0.96
16	21	0.49	34	5.4	0.1	1	13	837	849	837	852	0.87
17	21	0.0005	0.034	14.8	0.8	1	23	900	922	900	922	0.98
18	21	0.15	10	7.0	0.2	2	23	931	952	931	952	0.95
19	21	0.00092	0.062	14.0	0.3	1	23	960	982	960	982	0.97
20	21	0.34	23	5.9	2.1	1	23	989	1011	989	1011	0.94
21	21	0.15	10	7.0	0.2	2	21	1042	1060	1041	1061	0.93

Sequence Information

Coding Sequence: ATGATGCTGTTTAAAGGCAACAGTAGTCGTTTAGAgttgttaattgaaaaaattcataaccATAAAGAAAATTCCGAAATGGCAGATATCGTTTCCAcaggtTCTATTGGAACAGAACATGAAAGTTGGGGTTCAAATACTCCAGAACAAGCCTCGCCAGCTCCAAGTTCGTGCCCGACGCCGAGTTCTAGTTTAAGCGATGTTGCCGAAACTGATTTAGCATTTACTGTAGGAATAACTGAAACGACTCCTTACGCTTGTAAGATTTGCAATAAAGCTTTTGCTAGATCTTCCTTATTAAGTAAACACGAACAAtcCCACACTGATCAACTTCAATATAGATGTTCTTATTGTCCTCGTCTCTTTAAACATAAAAGATCTCGCGATAGACATATTAAATTACATACTggagacaaaaaatataaatgtgtACATTGCCAAACAGCATTTTCAAGAAGcgaCCATTTGAAAATCCATATGAAAACCCACGACAATAGCAAACCCTTTAGATGCCTAATATGTAATCGAGGATACAATACGGCTGCAGCGTTAACATCTCACCAGCAGAGCCattccaaacaaaattttgaaggaaattcTGAAAGCCTAAAATGCCTACAATGTCCAGACGTTTTCAATGGGTGTGATCAACTTCAGCTACACATGTCGACTTTCCACAACAGTATTTTGCCCAACTCCTCTACACCCAAACAATCTCCGATAGAACTAACAAAATGGGTTTGCATGTACTGCAGCAAAGACTTCCCAACGATCGACGATATGCAACACCACATTAACACAGATCACGGTGCTCTCGTAAACGGAAGCTTTTTAACGAATACAAACAACGTAATCGAACCCCCAAATAATAAAGACCCATCGATAAACGACGAACAAAGCGACGGTGCGCCAACTTATGCTTGCGATAGCTGCACGATGCATTTCGACTCGGTAGACACGCTAAGAGTTCACGAAAACTGCATACATTGGAAACCCCCTCAACCTTTAGCAACGCCTTCCAAAACTTTCCCAAAAGACTGCAACACTACTACTTGTCTAATCTCTTCTCAAACTCCAGAAACGTCTACTAACTCCGTATCCGTACAACCCATCCAACTTCAACCGACCGATTTAAGTCGCAAAAGAAAAAGTGGAGAAGAAGAAAAGGTATCTCCTAAACGAAATAATATGTCACTTCCGAGCGTTGCTAGTGCCTCATGTGAGTCgccaaaaaaagaagaatgGACTAGCTATATTTGTAGTATATGCGGTACGCCGTTGCCAAATTTTGCGTCGTTTATGGTTCATATGGATATTCACATGTCGGTCAATGCAACTCCGGCAAATGTCGTACTCGGAGGGTACTGTCCTCTATGTGGAGAAGCTTATAGGGATCAAACCGAATTAAATAATCACATCGTATTACACACTTTAACTTACAAGCCCGGCTGGTGTTGCAGAGTTTGCAAGAAGTTCTTTAACGATAATTTAGAAGACCTCCAAAGGCACTTGATGGAGAATCACGCTTGCACAACGTATAAATGTTGTGTTTGCGAACAACTCTTCGATAACAAAACGGCTATGTTGatgCATTTAACGAAGAAGCATAGCAACGAGTGTCAACACTACAGATGTAAATTTTGCCCAGaacaaatttttcacaatCAGTTAAGTGCAGAAATGCATATATCGCAACACGTCCCGCGCTTATTTAACCCAGCTCGTAAATCATCCACCTTAGGATCTTATCCCTTCCCAAACGACTATAGCGCAAGATTGGGAtcgacaataaaaaatttgcaatgtCCATTTTGTCGCCAGTGTTTTAAAGGCgaatatttacaacaaatgCATATTTTGAAAGACCACAAGGATTATTTAGAGGCTCATGGTTCGCGCGTAACCGAAGATTGTTCTTTAGAGCATATATCTCTGAGAGCAGGTCAAAGGGAAGTTTGTGCTACTTCACCGTCAGTTCCGTATACGAACTCGTTACCGTATGATAAGAGTTTAATCGAAAACATTATATGCGACCTTTGTGGTTCTTCCGATTTTAGCAGTGGGGCCGAATTGAGTTCGCATAAAAAATTGCATCAcgtcaaaactaaaataggACCAGTAAGTTTACAGTGCGCTTATTGTAACGAACATTGTAAATCTCGTTCGGATCTCGAAAACCACATGAAAAACCATCAAATAAATAGTAGTAAAGGTAAACATAAGTGTAATATTTGTGACGAAATTTATTCGTCGGCTTTAACTTTGGCGGAGCATAAACTATCCCATTGTAAAATCGTGTCTGGGAACACTTGTACTCAGTGTAAAGCGGTCTTTTCTGATGAGCAGACATTTTACTCGCATCAACTACAGCATAGCGCAGTCTTAAATAAGGCCAACTCTCAAATTTCCTTGCCGGCCAATTGTATAATCTGTTGTCAAACGTTACAAACTGACGTCGAAATAAAACTCCATgccaattttcatttacaacaCATACTTCAGAAAGAATATTTGTGTAATATGTGTAATAGGGTTTTTGATACTCGCACTGGAATAATTATACAaagttacgaaaaaaattgcgaaaatttacaaatatccGTATGTAAAGACTGCATGAATAAATGCGGGAGTAATAGTAGTTCGAATAGCCCACGATCTACACATATAAAAAGCGAAAATGTggataaaaaaatctattcgTGCCTCAAGTGCCCACAAACGTTTGATAACGAAAGCGACGTCAAAAAACATTCCTTAACCCATATTTCCAACGACGGTTCAAATAACGAATGCCACATTTGCAGAAGCATTTTTCCCACCCctttaaaacttcaattacACGTAATAGAACATAGTTTTTTCGGCACGTGCCAATTTAGATGTTACATTTGTAGTTCAGTATTTACAACTGCAAATGGTTTACTCTCACACATGTTAGAACACGGGACTAATTCAAAACCTTACGAGTGCGTTACATGccaaacaaaattctttttccaAACCGAATTAGATAATCACAAATATGAACACATTTTAGCCCAAGCAGCTGCAGCTcaatctattaatttaaataatttagacgAAACCGACTCGGCTGATATATTAAGAAAAGATATAAGTAAATGTCCATTCTGTGATACGGCGACGtcgcaaaattatttaaacattcaTATAAGATTTTGCCCACAAAATCcagattttaagaaaaaaaatgataccaaacctcgtaatcaatttttagaaagtgCCAGTATTACGGAAATTGAAGATAAAAGTGCGTAA
Protein Sequence: MMLFKGNSSRLELLIEKIHNHKENSEMADIVSTGSIGTEHESWGSNTPEQASPAPSSCPTPSSSLSDVAETDLAFTVGITETTPYACKICNKAFARSSLLSKHEQSHTDQLQYRCSYCPRLFKHKRSRDRHIKLHTGDKKYKCVHCQTAFSRSDHLKIHMKTHDNSKPFRCLICNRGYNTAAALTSHQQSHSKQNFEGNSESLKCLQCPDVFNGCDQLQLHMSTFHNSILPNSSTPKQSPIELTKWVCMYCSKDFPTIDDMQHHINTDHGALVNGSFLTNTNNVIEPPNNKDPSINDEQSDGAPTYACDSCTMHFDSVDTLRVHENCIHWKPPQPLATPSKTFPKDCNTTTCLISSQTPETSTNSVSVQPIQLQPTDLSRKRKSGEEEKVSPKRNNMSLPSVASASCESPKKEEWTSYICSICGTPLPNFASFMVHMDIHMSVNATPANVVLGGYCPLCGEAYRDQTELNNHIVLHTLTYKPGWCCRVCKKFFNDNLEDLQRHLMENHACTTYKCCVCEQLFDNKTAMLMHLTKKHSNECQHYRCKFCPEQIFHNQLSAEMHISQHVPRLFNPARKSSTLGSYPFPNDYSARLGSTIKNLQCPFCRQCFKGEYLQQMHILKDHKDYLEAHGSRVTEDCSLEHISLRAGQREVCATSPSVPYTNSLPYDKSLIENIICDLCGSSDFSSGAELSSHKKLHHVKTKIGPVSLQCAYCNEHCKSRSDLENHMKNHQINSSKGKHKCNICDEIYSSALTLAEHKLSHCKIVSGNTCTQCKAVFSDEQTFYSHQLQHSAVLNKANSQISLPANCIICCQTLQTDVEIKLHANFHLQHILQKEYLCNMCNRVFDTRTGIIIQSYEKNCENLQISVCKDCMNKCGSNSSSNSPRSTHIKSENVDKKIYSCLKCPQTFDNESDVKKHSLTHISNDGSNNECHICRSIFPTPLKLQLHVIEHSFFGTCQFRCYICSSVFTTANGLLSHMLEHGTNSKPYECVTCQTKFFFQTELDNHKYEHILAQAAAAQSINLNNLDETDSADILRKDISKCPFCDTATSQNYLNIHIRFCPQNPDFKKKNDTKPRNQFLESASITEIEDKSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00951198;
90% Identity: -
80% Identity: -