Mfla012782.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Malthinus flaveolus
Gene Symbol
RHOBTB1
Assembly
GCA_950108345.1
Location
OX467287.1:32218711-32222871[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 2.8e-10 7.1e-08 32.8 0.0 8 51 261 303 254 317 0.80
2 3 5.4e-06 0.0014 19.0 0.0 36 101 351 414 348 420 0.84
3 3 1.5e-16 3.8e-14 53.0 0.1 5 108 444 546 441 548 0.93

Sequence Information

Coding Sequence
ATGGACAATGAACAGCCCCACCAGGAGCTCGTGAAATGCGTCGTGGTGGGCGACACGGCCGTGGGAAAGACTAGGCTTATCTGCGCGAGAGCTTGTAATCAGCAGGTCTCCTTGGCCCAACTTCTAGCCACCCATGTACCCACCGTTTGGGCTATCGATCAGTATCGCATCTACAAAGATGTGTTGGAAAGATCGTGGGAGGTAGTAGACAGCGTGAACGTATCCCTGCGTTTATGGGACACTTTCGGGGATCACGAAAAAGACAGAAGATTTGCGTACGGTCGGTCGGACGTCGTTTTGTTATGTTTTAGCATCAACAATCCCATTTCTTTGAGAAATTGTCGTTTGATGTGGTATCCCGAAATTAGACGCTTCTGTCCAAATACACCGGTGATATTGGTGGGCTGTAAAAACGACCTTAGATTTATGTATCGCGACGAAGCGTATTTGACTTTCTTTAGAGATCGTAGTCCTTTCGTTAGAGCCACTCGTAAAACCGATTTAGTGATGCCCGACGAAGCGCGCGACGTCGCGCAAGAACTAGGGCTTTATTATTACGAGACGTCCGTTTTGACTTATTTTGGCGTAAACGAGGTATTCGAAAATGCCATACGCGCCGCATTACAAGCCCGTCGTCAACAGCGCTTTTGGCAGACTAAtctaaaaaaagttcaaagacCTCTGCTTCAAGCACCTTTCAAACCGCCTCCTCCTCCAAAACCGGAAGCTAAAGTCTGCAATAGCAATTATGCGGAGCATTTATGTCAATTATGGTTGGGGAGAAATCATTCCGACGTAGTATTAGTAGTCGGCTCCGTAGGTTTTTCGGCTCACCGATTCGTATTATCGGCTGCCAGTCCCGCATTCTATCGTTTATTTGCGCTAGAAATGTCGGCTGATATGACACGCAGTACTAGCGATTCTAGTATGGTCAGTTCGTTAGGAGATTTTAGCGATGACAACGAAAGTTTACTTCGAGCCGAACAAAGAACGTGGCGTCGTCGAGCCAGTTGTCAGGCTTTGTTACCGGCGAGAGAACTTGATCATCCCGCCTTTCAAGCTATCAGAAGTGTACAAAATGAAGGACAAACTGTCGTGACTTTGGGGAAATTGGTCACTGCTCCTGCTATCCGCCAGTGTTTACAGTTTATGTATACGGGAACTGTCGATCAAAGACTGATGGATTTGCAGGAAACACGTCAAGTTGCAGAGTTTTTGGAATTATCGCAACTCTTAGTATTATTGGTAGAAATGCAAAACTGTGGAAGTATCGAGCAATTACAAGAAAATCACGAAGTGtatttaagaagaaaattgcAAGACGTATGTTTAGATCAGGGACTATTTGCCGATATCGTGTTCGAATTAGATGATGGTGCTTGTGCCGCTCATAAAGCAATGTTAACTGCACGTTGCGACGTTATGAAAGCAATGTTTTGTGGCGATTTCCGCGAAAGCCAAGCAAAAGTGataGAATTTCCGGGAGTACGCGAATATACATTCCATAAGTTGCTGTGTTATTTCTACACAGACGATGTTCCTGCCGTATCGGCTGCCCGTTGCGTTAATTTGTTGGAATTGAGTAACCGGTTGTGTTTGCCTCGATTGGTTAATCTCGTAGAAAAGAGAGTTATCGAGGATTTGGAAAGGTTGCAAGCTTCAGAGACTATCGAACAATGTTTGCGCCTACTCGAGCCCGTCAAgTTGCACAACGCCCATCAACTGGCAGATTGGTGTATGAATCATTTGTGcgttaattacaataaactcTGTCGCATGTCGCCTAGAAGTTTGCGTTTATTACATCCGGACAATCAAGCATATCTAGTTGAACATCGCTGGCCTCCAGTTtggtatttaaaagactacgATTATTACCAAAAGTGTCTAGTAGAACGTGATCGTGAGACCAAACACGCTCTGAAATCCAGCTCGGGTTGCCTATGTTTCTCACGTAAATCCGAATCCGACCCGGCTCTAGCGGGCCACATATAA
Protein Sequence
MDNEQPHQELVKCVVVGDTAVGKTRLICARACNQQVSLAQLLATHVPTVWAIDQYRIYKDVLERSWEVVDSVNVSLRLWDTFGDHEKDRRFAYGRSDVVLLCFSINNPISLRNCRLMWYPEIRRFCPNTPVILVGCKNDLRFMYRDEAYLTFFRDRSPFVRATRKTDLVMPDEARDVAQELGLYYYETSVLTYFGVNEVFENAIRAALQARRQQRFWQTNLKKVQRPLLQAPFKPPPPPKPEAKVCNSNYAEHLCQLWLGRNHSDVVLVVGSVGFSAHRFVLSAASPAFYRLFALEMSADMTRSTSDSSMVSSLGDFSDDNESLLRAEQRTWRRRASCQALLPARELDHPAFQAIRSVQNEGQTVVTLGKLVTAPAIRQCLQFMYTGTVDQRLMDLQETRQVAEFLELSQLLVLLVEMQNCGSIEQLQENHEVYLRRKLQDVCLDQGLFADIVFELDDGACAAHKAMLTARCDVMKAMFCGDFRESQAKVIEFPGVREYTFHKLLCYFYTDDVPAVSAARCVNLLELSNRLCLPRLVNLVEKRVIEDLERLQASETIEQCLRLLEPVKLHNAHQLADWCMNHLCVNYNKLCRMSPRSLRLLHPDNQAYLVEHRWPPVWYLKDYDYYQKCLVERDRETKHALKSSSGCLCFSRKSESDPALAGHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01345782;
90% Identity
iTF_00838700;
80% Identity
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