Basic Information

Insect: Macrosoma leucophasiata
Gene Symbol: Hr39
Assembly: GCA_036365455.1
Location: JAWQUS010000025.1:6386246-6404256[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.47 4.9e+03 -2.6 2.5 76 153 101 196 50 230 0.40

2 5 3 3.1e+04 -7.1 10.3 106 181 252 328 129 360 0.49

3 5 8.2e-08 0.00085 19.6 0.1 1 20 441 460 441 479 0.90

4 5 0.013 1.3e+02 2.5 0.0 75 117 484 524 460 539 0.76

5 5 1.9e-64 2e-60 206.1 0.0 201 408 541 757 492 757 0.84

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.47	4.9e+03	-2.6	2.5	76	153	101	196	50	230	0.40
2	5	3	3.1e+04	-7.1	10.3	106	181	252	328	129	360	0.49
3	5	8.2e-08	0.00085	19.6	0.1	1	20	441	460	441	479	0.90
4	5	0.013	1.3e+02	2.5	0.0	75	117	484	524	460	539	0.76
5	5	1.9e-64	2e-60	206.1	0.0	201	408	541	757	492	757	0.84

Sequence Information

Coding Sequence: ATGAACAGCGCGATGTCCAATGAGAGCGATCCGGTAAAAGTGGAAGGTGGGCATGTATCAGTCACCACCATCAGCATGTCGGGCCCGGAGACCAGTAGTGGTCAATTCTCGTACAGTTCGAGCGGCGTGCGCATCAGTGTGTCCTCGGAACCACACGACGAGGACTCAACTGATGCTGAAATCTCCAAAATTGACTTCACACAGCACCAATACGAAGTAAACATGAGGAACAAGAAGAAGCGTTCATCGAGCGGGCAGTGCGACAGTCAGAGCAACGAGCAGGAGCGGCCCATGTCGTGGGAAGGCGAGCTGTCAGATTCCGAAATGGTCATAGACACCAGCGTGACTAACGACGAAAACAGCAGTTCCTTGGACATGCAATCATCCAGGGATTCCATCGACACGCTGCGTAATGTCACAATCAAGACGGAACCCTTGAAGACAGAAGCATTCCAGAGCTTGGACGATCACAGAGTACTCGACTTGAAGTACACAGCGCCTTTGCAGCCGCATCAGAGGAGTCTCAGTATGAACAGGATATCAGTACTCACAGACAATACATCTCTCTCGCTCGCACGACGACCATCTTCCCCAACGAGCAGCGCCAAGTCCTTGGCTCTCGACCAGTACGACCACACTCTGCCGCTCATGGCCCAAAACCCGGTCACCGAAGTGCAGAACTTGACCATCAAGAAGGAACAGTTGTCCGAGTTAAAATGCGAACCTTCAGTGGGCATGGACAAGTTGCTGGGCCTGCACGGTTCCCCACTGCTGGGCCGCCTGCCGCGTGTCCAGTCCAGCGCCAGCACCGATTCCGCCGTGCATTCTATGTACACGCATagCGTATACAGCAGTCCTTCGGCCAGTCCACGCCCGGCGCGCCATTACACTCCGTCGTTGTCGCGCAACAACAGCGACGCTTCTCACTCCTCATGCTACTCCTACAGCTCCGAGTTCTCGCCTACGCATTCGCCCGTGCAGAGTCGCCATCCGCACGTGTTGTATCGCAGCGACGCGGTATTCCCCGCGTCCCCCGCTCACGACGAGGACGTAGAAGACGAACGACTGCATCACCACCAGGGCATCAGCCGGCAGCAGCTTATCAACAGCCCATGTCCCATCTGCGGTGACAAGATCAGCGGATTCCACTACGGGATATTCTCGTGCGAGTCGTGCAAGGGGTTCTTCAAGAGGACCGTGCAGAACCGCAAGAACTACATGTGCTTGCGCGGTGGGAACTGTCCTGTCACTGTGGCCACGAGAAAGAAGTGTCCGGCTTGCCGCTTCGATAAGTGCCTTGGATGTGGAATGAAACTTGAAGCGATAAGGGAAGACAGGACTCGAGGCGGGCGGTCGACGTACCAGTGCTCGTACTCCCTGTCGGGCGCCGCGTCCACCGGCTCGCTGCTGTCTGCGCACGCGCCGAGCACACTGCGGCACGCCTCCAGCCTCACTTgtGTTAACGGTCCCGGGTCATACAGTCGAGGAGAATCCAGCAACAGTCGGCTTACGCCAGACATACCGCCGTTATTACAGGAAATAATGGACGTGGAACACCTCTGGCAATACAACGAGTCGGAGCTAAGTAGACTGGGGAAGTCCGGCAGTCCTTCGGCCAACCCACTGTTGGCTGCGAGTGGAATTACTGCCCAGAACTCCAGCGCCGACTTCCTCGCAGACCTGTGCAATATCGCCGACCACAGACTGTACAAGATCGTCAAATGGTGCAAGAGTCTGCCGCTGTTTAAGAATATATCGATCGATGACCAGATCTGCCTGCTGATCAACAGCTGGTGCGAGTTACTGGTGCTGTCGTGTTGTTACCGCGGCGTTGGCACTCCGGGTGAAGTGCGAGTTGGTGGCGGCCGCGGCATCACTCTACATCAGTCTGCCAAGTTTGGGTTGACGCCGTGTATAGAACGAATGCTCAGTTTCACGGACCACTTGCGACGGTTAAGAGTGGATCGATACGAATACGTCGCGCTTAAAGTCATCGTACTTCTCACTtcagATGCGCCCGAGTTGCGCGAAGCAGAGAAAGTGCGAGCGTCCCAAGAGAAAGCGCTGGCGGCATTACAAGCGTACACTGCCTCGCATTCGCCCGACACGCCCGCCAAGTTCGGCGAGCTGTTACTGCGTATACCCGAACTGCAGCGTACCTGCCAGTTCTTCATGCAAGTCGGCAAAGAAATGCTCAACCCAGCCAACAAGAGTAAGGACGGCGAAGGACCAAGTTTCAATTTGCTAATGGAACTCCTCAGGGGTGACCATTGA
Protein Sequence: MNSAMSNESDPVKVEGGHVSVTTISMSGPETSSGQFSYSSSGVRISVSSEPHDEDSTDAEISKIDFTQHQYEVNMRNKKKRSSSGQCDSQSNEQERPMSWEGELSDSEMVIDTSVTNDENSSSLDMQSSRDSIDTLRNVTIKTEPLKTEAFQSLDDHRVLDLKYTAPLQPHQRSLSMNRISVLTDNTSLSLARRPSSPTSSAKSLALDQYDHTLPLMAQNPVTEVQNLTIKKEQLSELKCEPSVGMDKLLGLHGSPLLGRLPRVQSSASTDSAVHSMYTHSVYSSPSASPRPARHYTPSLSRNNSDASHSSCYSYSSEFSPTHSPVQSRHPHVLYRSDAVFPASPAHDEDVEDERLHHHQGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYMCLRGGNCPVTVATRKKCPACRFDKCLGCGMKLEAIREDRTRGGRSTYQCSYSLSGAASTGSLLSAHAPSTLRHASSLTCVNGPGSYSRGESSNSRLTPDIPPLLQEIMDVEHLWQYNESELSRLGKSGSPSANPLLAASGITAQNSSADFLADLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLVLSCCYRGVGTPGEVRVGGGRGITLHQSAKFGLTPCIERMLSFTDHLRRLRVDRYEYVALKVIVLLTSDAPELREAEKVRASQEKALAALQAYTASHSPDTPAKFGELLLRIPELQRTCQFFMQVGKEMLNPANKSKDGEGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00642460;
90% Identity: iTF_01018623;
80% Identity: iTF_00942927;