Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.0024 6.2 9.0 0.0 21 47 12 38 6 44 0.86

2 10 0.9 2.3e+03 0.7 0.0 21 44 40 63 36 72 0.81

3 10 1.3 3.2e+03 0.2 0.0 20 43 67 90 61 94 0.82

4 10 0.0026 6.7 8.8 0.0 21 47 96 122 79 127 0.83

5 10 0.16 4e+02 3.2 0.2 21 43 124 146 120 151 0.88

6 10 0.0009 2.3 10.3 0.4 10 44 140 175 138 183 0.75

7 10 0.34 8.6e+02 2.1 0.0 21 43 180 202 177 208 0.86

8 10 2.8 7e+03 -0.8 0.0 21 45 208 232 199 241 0.78

9 10 1.3 3.3e+03 0.2 0.1 23 43 238 258 231 263 0.83

10 10 0.015 39 6.4 0.0 21 43 264 286 251 291 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.0024	6.2	9.0	0.0	21	47	12	38	6	44	0.86
2	10	0.9	2.3e+03	0.7	0.0	21	44	40	63	36	72	0.81
3	10	1.3	3.2e+03	0.2	0.0	20	43	67	90	61	94	0.82
4	10	0.0026	6.7	8.8	0.0	21	47	96	122	79	127	0.83
5	10	0.16	4e+02	3.2	0.2	21	43	124	146	120	151	0.88
6	10	0.0009	2.3	10.3	0.4	10	44	140	175	138	183	0.75
7	10	0.34	8.6e+02	2.1	0.0	21	43	180	202	177	208	0.86
8	10	2.8	7e+03	-0.8	0.0	21	45	208	232	199	241	0.78
9	10	1.3	3.3e+03	0.2	0.1	23	43	238	258	231	263	0.83
10	10	0.015	39	6.4	0.0	21	43	264	286	251	291	0.86

Coding Sequence: ATGTCTACGGCAACCAATTTAACAGCACATAACGAAGAAAAGCCGTATAAATGTGATATATGTGAAAAAAAGATTTCTACATCATCAGATTTAACAAAGCATTTGAGGACGCATACGGGTGAAAAGCCCTTTAAATGCGATTTATGTGATCAAGCCTTTTCTCAAGCACATTATTTAACTCTGCATACAAGGAAACATAACGGAGAAAAGCCGTACAAATGTGATCTCTGTGATAAAAGGTTTTCTACATCATCAGCATTAACAAAGCATACAAGGACACACACCGGAGAcaagccttataaatgtgatatcTGTGATCAAGCTTTTTCtcagaaaacaaatttaaaaaaacacacaaggATACACACTGGAGAAAAGCCGTATGAATGTGATATCTGTGTTCAAAGTTTTTCCCAACCACATACTTTAAAAACCCATAAAAGGACACATACCGGTGAAATTGCGTATAAATGTGAAATCTGTGATCGTGCCTTTTCTCAAGCATATAATTTAAGACGGCATACAATGACACATACCGGAGAAAAACCTTACAAATGTGATATTTGTGATAAGGGGTTTTGTACaacattagatttaaaaaggcaTAAAATGACCCATACCGGAGAAACGCCATATAAATGTGATAAGTGTGATAAGGGGTTTTGTACATCATTAGAACTAACAAGGCATACAAGGACACATACCGGTGTTAAACCGTATAAATGTGATATATGTGATCAATCCTTTTCTCAAGCACATCATTTAACGGGGCATACAAGGACACATACCGGagaaaagccttataaatgtgatatcTGTGATCAAGCTTTTTCtcagaaaacaaatttaaatactcataaaaGGACACATACCGGTATAGAGccgtataaatatgttatttgcGATTTAGCGTTTTCTAAagcatcaaattaa
Protein Sequence: MSTATNLTAHNEEKPYKCDICEKKISTSSDLTKHLRTHTGEKPFKCDLCDQAFSQAHYLTLHTRKHNGEKPYKCDLCDKRFSTSSALTKHTRTHTGDKPYKCDICDQAFSQKTNLKKHTRIHTGEKPYECDICVQSFSQPHTLKTHKRTHTGEIAYKCEICDRAFSQAYNLRRHTMTHTGEKPYKCDICDKGFCTTLDLKRHKMTHTGETPYKCDKCDKGFCTSLELTRHTRTHTGVKPYKCDICDQSFSQAHHLTGHTRTHTGEKPYKCDICDQAFSQKTNLNTHKRTHTGIEPYKYVICDLAFSKASN

Sequence clustering based on sequence similarity using MMseqs2