Basic Information

Insect: Macrosiphum euphorbiae
Gene Symbol: -
Assembly: GCA_949089665.1
Location: CARXXK010000001.1:117045035-117054511[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 1.1e-05 0.0015 20.8 3.6 1 23 206 228 206 228 0.98

2 14 0.0011 0.15 14.5 3.7 1 23 234 256 234 256 0.97

3 14 0.0033 0.43 13.0 0.6 1 23 345 368 345 368 0.95

4 14 8.5e-05 0.011 18.0 1.4 1 23 400 422 400 422 0.98

5 14 0.1 14 8.3 1.2 3 23 441 461 440 461 0.91

6 14 0.2 26 7.4 0.1 3 23 473 494 472 494 0.90

7 14 0.0042 0.55 12.7 1.3 1 23 501 523 501 523 0.98

8 14 0.0092 1.2 11.6 3.0 5 23 532 550 529 550 0.93

9 14 0.015 1.9 11.0 0.0 2 23 556 577 555 577 0.96

10 14 5e-05 0.0065 18.8 0.2 1 23 593 615 593 615 0.98

11 14 0.00054 0.071 15.5 0.2 3 23 623 643 621 643 0.97

12 14 3.7e-05 0.0048 19.2 0.1 1 23 649 671 649 672 0.95

13 14 0.0012 0.16 14.4 1.6 1 23 685 707 685 707 0.96

14 14 9.2e-06 0.0012 21.1 0.1 2 23 985 1007 984 1007 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	1.1e-05	0.0015	20.8	3.6	1	23	206	228	206	228	0.98
2	14	0.0011	0.15	14.5	3.7	1	23	234	256	234	256	0.97
3	14	0.0033	0.43	13.0	0.6	1	23	345	368	345	368	0.95
4	14	8.5e-05	0.011	18.0	1.4	1	23	400	422	400	422	0.98
5	14	0.1	14	8.3	1.2	3	23	441	461	440	461	0.91
6	14	0.2	26	7.4	0.1	3	23	473	494	472	494	0.90
7	14	0.0042	0.55	12.7	1.3	1	23	501	523	501	523	0.98
8	14	0.0092	1.2	11.6	3.0	5	23	532	550	529	550	0.93
9	14	0.015	1.9	11.0	0.0	2	23	556	577	555	577	0.96
10	14	5e-05	0.0065	18.8	0.2	1	23	593	615	593	615	0.98
11	14	0.00054	0.071	15.5	0.2	3	23	623	643	621	643	0.97
12	14	3.7e-05	0.0048	19.2	0.1	1	23	649	671	649	672	0.95
13	14	0.0012	0.16	14.4	1.6	1	23	685	707	685	707	0.96
14	14	9.2e-06	0.0012	21.1	0.1	2	23	985	1007	984	1007	0.96

Sequence Information

Coding Sequence: ATGGACACTGACTTTGTCGAAGAAATTGTGTCCGTCCATTCTGGTAACCAAACACTTGATTTTGATAGTAAGGACAATATTTTATGTCCAGGCACTGTTGTTGACTCTATTGTCAAGACCGAGTTTTTCAGTCCGGATGACATTGACGGTTTGTCATCTGACGATTGTTTAATACAAACCATTGGGTCCTCGTATTTCACCAACAGTAGTACACGCACAAATGAGCTCAATAATATGACTAGAGCGGTCATGGAATCTGTGCCATATGCCGATGGGTTACAATACTTAGCTGCCATATCTTCATTCAGTGATAATTTTAAGGAAATGGATCAACAGCAGGAAATCAAACAAGAGCCTGTTGATTTATTTGAGTCTAGTGATGATGAAGTCGTCAAACAAATGACCCAAGAGgaataccaaaattattttgatgtcCAAGAAGAAGTAGTTGTTCAAGAATGCCCCGAGCAGGAAATAATCACTCAAAGTTGGGACATGAACCGCTCTACCGATATTAACAAcaTATTAGAAACAGATGTTAAATGTATGTCATCAACTGTTGATGTTGACATACCAATACCTGAAGGCGAAGAAGCTTCATCTTCTGTTAATCCATATCCATGTGATTTTTGTAGTCGGAGGTTTAATCGAAAATCACATCTTATGAACCATATGGTTACCCATCAATCCGAGCGTCCCTTTTGTTGTGCATTATGTGGTGTCCGTTATCGTCGTAAATGTGATTTAGCCAATCATATGAAAATTCATATTGGTCCTGATAATCCATCAGATTGTGgtttagataGCCAAAATGTATCTGTTACAAAAGTAATGAACAAATTAATGTTCATGGATCCAATACAGAGAAGGAGTGTTACACCTGGTGAAGATTCTGAAGATAAAGGAGACATATATCAGGAACAAAGTACAAAAAACCGTGGCCGTGGTAAAGGTCGGGGTAGAGGAAAAGGTCGTCCAATGAAAGATCGCTTATTTACTCTTGGTTGGAATTCAGAAATTTACTCAAAACCACATACATGTAACCCATGCGGAATTTCATTTACACGCGAAAAAGCTCTTCTTAATCATGCTCGTCTTAGTCATGTTGATGATGGTGTAAATATTGTGACTACTCAAAAATCAAATTCAGATAGTTACGAGCTTACAATATTGTccaataataaatgcaatgatTCTTACTCTTGTGATTCATGTGGTGCAGTATTTAAcagatttgattttttaaaacgtcATCAAAGgCAGCATATGAAAAAAGAACTTGGAAACGTTGAAGAAGAAATATATGAAGAAGCACAAATGTGTATACATTGTGGATTGTTCTTTAAGTCTATGTCTGAGTTAGAAATGCATACTGAGCAACATTTGATTCCTACAAATATTTCAGaaAAATCAAATTGTTTAGCTTGTGGTGAAACATTTGATAGTACAGATGAGCTGTCTGACCATGTGTCTCAAATTCATACTGATTCATTACCTGAATTTTCATGTAAACTTTGTGCAAAACCATGTAAAGACGATAAAGctcttcaaaaacatttaatgatTCATGACACAtctgataataattgtataatgtgtGGTAAAAGATTTCATTCCAGAGCACGTCTTAAACGacacATGGTAACTCATCGAGAAAAAGGAGTTGTTTGTGACATATGTGGTGAAGAATTAGCTGACAAACGAGCACTTATTAATCACAAAGCTAGTCATTCCAATACTGTTAGTATTTCACGAAATTCATtgactgaaaaaatatttccttGTACTAGTTGTGGCAAAgtatttggATCTAGATCATCTCAACAAATACATATACGAATACACACAGGAGAACGGCCTTATGGTTGTAGATATTGTAACAAAGCTTTTGCTGATGGTGGTACACTTCGAAAACATGAACGAATACACACTGGTGAAAAGCCATATGCTTGTCCTGTCTGTCCAAAGGCTTTCAATCAAAgagttgTATTGCGCGAACACATACGTGCACATCATGCTGGAACTGAGGCAAAGGGTGGTcaagtaaatttttatgaatgtaaAGTGTGTGGTTATTTGTTCCGATCTTCAATGGAGCTTTGTTCACATTTAGTTCAGCACAGTGATGAAAATACTAAAAGATCTAGAGTAGTTcctGTTGGACCTCGCAAATATAAGCGTCGGAGCAAGTTGGGTAATCGAAAAGATACATGGTGCTTAGTAGAAAAAGTCTTAGTTATGTCAGGACAGTCAGACACAGAGAGCTGTGAAGATGAACCAATACCTACAGCGGAAGAGCAAGCTGTACAATCAATTATGGAACAAGATGATGTGCCTTACGATCCTCCATCTGTAGCTAGTCCTCCTAAAAGGCCAGTTAAAACCTACAAACTTGTTAATGGCAGGTTAGTGAGAACTGAACCAAAGGCACAAATGATAAATGAACCAAAAAACGAAGTTGTCAAATCAGAATCTATAccaaaaaaacattgttttgtACTTAAAGACGGAGAGTGCACTAGAACATGTTCTACTGTTCTTTATTATTCTTCAAGATCTAATCCATCAGATATGGATTCATTATTAGGAGAGGAATCGAAAGAAAATGATAATCCAGAAGAACCTGAAGATCAGATATCTGTAGAGGAAGATGATTTAACAGACCATACATTAGAACGAGTTAGTATAGAGTCAATATTTAACGTAGAAGATTTAGATAACATTGGTGACATTTGTAACATTGATTTTCCTGATGAACCTGGAGtagaatattatgttgaaaataatagtgAATATGATGATCATTTGTCTTTAATCGTGGAAAATGTTGATTCAAATAGTGATTGCGTGGTTGAAACAGAACTAGTGTTTGATACAGATTATGTTGAAGAGGTTGGTGCTAATATTGAGCTTAGTACCGAAGAAATGGCTCCTGTATTTGCAGAAGTTATTTCTTGTGATATTTGCGATGAAGTATTTGAGGATAGAAAAGAGCTTATGAGACACATTCAAACCATGCATATTGGATAA
Protein Sequence: MDTDFVEEIVSVHSGNQTLDFDSKDNILCPGTVVDSIVKTEFFSPDDIDGLSSDDCLIQTIGSSYFTNSSTRTNELNNMTRAVMESVPYADGLQYLAAISSFSDNFKEMDQQQEIKQEPVDLFESSDDEVVKQMTQEEYQNYFDVQEEVVVQECPEQEIITQSWDMNRSTDINNILETDVKCMSSTVDVDIPIPEGEEASSSVNPYPCDFCSRRFNRKSHLMNHMVTHQSERPFCCALCGVRYRRKCDLANHMKIHIGPDNPSDCGLDSQNVSVTKVMNKLMFMDPIQRRSVTPGEDSEDKGDIYQEQSTKNRGRGKGRGRGKGRPMKDRLFTLGWNSEIYSKPHTCNPCGISFTREKALLNHARLSHVDDGVNIVTTQKSNSDSYELTILSNNKCNDSYSCDSCGAVFNRFDFLKRHQRQHMKKELGNVEEEIYEEAQMCIHCGLFFKSMSELEMHTEQHLIPTNISEKSNCLACGETFDSTDELSDHVSQIHTDSLPEFSCKLCAKPCKDDKALQKHLMIHDTSDNNCIMCGKRFHSRARLKRHMVTHREKGVVCDICGEELADKRALINHKASHSNTVSISRNSLTEKIFPCTSCGKVFGSRSSQQIHIRIHTGERPYGCRYCNKAFADGGTLRKHERIHTGEKPYACPVCPKAFNQRVVLREHIRAHHAGTEAKGGQVNFYECKVCGYLFRSSMELCSHLVQHSDENTKRSRVVPVGPRKYKRRSKLGNRKDTWCLVEKVLVMSGQSDTESCEDEPIPTAEEQAVQSIMEQDDVPYDPPSVASPPKRPVKTYKLVNGRLVRTEPKAQMINEPKNEVVKSESIPKKHCFVLKDGECTRTCSTVLYYSSRSNPSDMDSLLGEESKENDNPEEPEDQISVEEDDLTDHTLERVSIESIFNVEDLDNIGDICNIDFPDEPGVEYYVENNSEYDDHLSLIVENVDSNSDCVVETELVFDTDYVEEVGANIELSTEEMAPVFAEVISCDICDEVFEDRKELMRHIQTMHIG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01167906;
90% Identity: iTF_01033209;
80% Identity: -