Basic Information

Insect: Macrosiphum euphorbiae
Gene Symbol: hmg20a
Assembly: GCA_949089665.1
Location: CARXXK010000002.1:72555472-72559435[-]

Transcription Factor Domain

TF Family: HMG
Domain: HMG_box domain
PFAM: PF00505
TF Group: Other Alpha-Helix Group
Description: High mobility group (HMG) box domains are involved in binding DNA, and may be involved in protein-protein interactions as well. The structure of the HMG-box domain consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin. Many of these proteins are regulators of gene expression. HMG-box proteins are found in a variety of eukaryotic organisms, and can be broadly divided into two groups, based on sequence-dependent and sequence-independent DNA recognition; the former usually contain one HMG-box motif, while the latter can contain multiple HMG-box motifs. HMG-box domains can be found in single or multiple copies in the following protein classes: HMG1 and HMG2 non-histone components of chromatin; SRY (sex determining region Y protein) involved in differential gonadogenesis; the SOX family of transcription factors [1]; sequence-specific LEF1 (lymphoid enhancer binding factor 1) and TCF-1 (T-cell factor 1) involved in regulation of organogenesis and thymocyte differentiation [2]; structure-specific recognition protein SSRP involved in transcription and replication; MTF1 mitochondrial transcription factor; nucleolar transcription factors UBF 1/2 (upstream binding factor) involved in transcription by RNA polymerase I; Abf2 yeast ARS-binding factor [3]; yeast transcription factors lxr1, Rox1, Nhp6b and Spp41; mating type proteins (MAT) involved in the sexual reproduction of fungi [4]; and the YABBY plant-specific transcription factors.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 6.8 1.4e+04 -1.5 0.5 42 61 40 57 38 63 0.66

2 6 3.9e-20 7.8e-17 63.4 1.2 1 69 64 132 64 132 0.99

3 6 10 2e+04 -2.0 0.1 19 28 160 169 155 170 0.80

4 6 10 2e+04 -2.0 0.1 19 28 177 186 172 187 0.80

5 6 10 2e+04 -2.0 0.1 19 28 194 203 189 204 0.80

6 6 5.3 1.1e+04 -1.1 0.1 19 28 211 220 205 233 0.75

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	6.8	1.4e+04	-1.5	0.5	42	61	40	57	38	63	0.66
2	6	3.9e-20	7.8e-17	63.4	1.2	1	69	64	132	64	132	0.99
3	6	10	2e+04	-2.0	0.1	19	28	160	169	155	170	0.80
4	6	10	2e+04	-2.0	0.1	19	28	177	186	172	187	0.80
5	6	10	2e+04	-2.0	0.1	19	28	194	203	189	204	0.80
6	6	5.3	1.1e+04	-1.1	0.1	19	28	211	220	205	233	0.75

Sequence Information

Coding Sequence: ATGTTTCTATGCTTAGTATTTATAAGGAAAATAACTCGATCAAGGACaatgatgaataataaaaacacttgGTGTATGGACAAGTCAGGTCAAGATAAAGAAGTCGGTAAAAATGGCATGCCAACAAAAGATAAGAAAAATTATCCTGAAAAGAAAACACGTAAAACTTATTTACGTGACAAAAGAGCTCCAAAACCTCCACATAatgGATACATACGGTTTTTGAATGATAGACGTCAACAATTTTCATCTCAAAATCCCAATTTACTATTTtctgaaataactaaaatattagcTACTGAATGGAACCAAATGTCAGCAGAAAAAAAACAaacATACCTTTCAGCCGCTCAACAAGAACGAGTAAAATATGTTGAAGAATTAGAGGCTTATAAAAAGACTGATGCATATAGAAATTTTCAGGAGTTCAAATCGAACAGAAAGAAATTTGATATCACTATCAAAaaagatcaaggaataaaaaaagaaaacccatctaatgataacaaatttaaaaaggatcaaggaataaaaaaagaaaacccatctaatgataacaaatttaaaaaggatcaaggaataaaaaaagaaaacccatctaatgataacaaatttaaaaaggatcaaggaataaaaaaagaaaacccatccaatgataacaaaattaaaaagggtcaagaaataaaaaaagaatacttacctaatgataacaaatttagaaagGAccaagaattgaaaaaaataaaaccatctACAACAAACATTGGCGATCAAGAATTTATGAAAGGAATACCATCTACATCTAGTGACAACAGTAATACAGTTAATGACTTACCTATATTTACTGAAGAATTCCTAAACTTTAATAAAGctaGAGATAGTGAACTAAGGAATCTTCGTAAAAAGGTAACAGATCAAGAACAAGAAGTATGTGTCTTAGATAAACATATTGAAAACATGCAAAATGCTAGTATCAAACTAGTGGCTATTAATGAACAACTCAATGCTGGATGTTCAAAGTATGAACAGTATTTAGTTAAACTACGATCTCGACTTTTGGATGTTTTTGCTAATACTGCATTCCcggGCAGGGGTGCACTGGCCAGGTGTGCTAGTGTGCCGCAGCACACCGGGCCGGCCATTATGTGTGGGTTGGGCCGCCGGGGCATTTGA
Protein Sequence: MFLCLVFIRKITRSRTMMNNKNTWCMDKSGQDKEVGKNGMPTKDKKNYPEKKTRKTYLRDKRAPKPPHNGYIRFLNDRRQQFSSQNPNLLFSEITKILATEWNQMSAEKKQTYLSAAQQERVKYVEELEAYKKTDAYRNFQEFKSNRKKFDITIKKDQGIKKENPSNDNKFKKDQGIKKENPSNDNKFKKDQGIKKENPSNDNKFKKDQGIKKENPSNDNKIKKGQEIKKEYLPNDNKFRKDQELKKIKPSTTNIGDQEFMKGIPSTSSDNSNTVNDLPIFTEEFLNFNKARDSELRNLRKKVTDQEQEVCVLDKHIENMQNASIKLVAINEQLNAGCSKYEQYLVKLRSRLLDVFANTAFPGRGALARCASVPQHTGPAIMCGLGRRGI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -