Meup032864.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Macrosiphum euphorbiae
Gene Symbol
Rfx2
Assembly
GCA_949089665.1
Location
CARXXK010000003.1:52771796-52780361[+]

Transcription Factor Domain

TF Family
RFX
Domain
RFX domain
PFAM
PF02257
TF Group
Basic Domians group
Description
RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 6.2e-35 7.3e-31 108.5 0.0 3 78 251 326 249 327 0.97
2 3 0.13 1.5e+03 1.8 0.1 6 38 456 486 452 508 0.73
3 3 5.4 6.4e+04 -3.4 0.0 23 43 714 734 708 736 0.84

Sequence Information

Coding Sequence
ATGGCGACTTCTGTGGGGAGTAGAATCAAATTAGAAGGGTCTGCAGGTACTGGCtcccaaattaatattatacctgttgTAACAGCAGATAGAGTTGGTCAAACTCTTGTCGTACAACCAGTACAACAAAGTTTTGTGAACGTCAACAATAATGGACAACTTGCAAATGCTACATTGTATGCAGCTAGTGCAGTTCATGATGATGGATCTAATAAATCAACGGATGATGATGAACATCACCTAGATCATAAAGATAGGAAGTTTTCTACAGTTACTGTTGATAATGACCATTATATTGTTGCAAAATCAGAAGGGACACATGGAACATATTATACTTCCCTTACACCGGTACCTACGTTGGttcccAAAGTAGAACCTATTGATTATGATGATGTTGGTCAATCTCCTTATGTACAGTATGTTGAAGGAATTGGCGAACAAGCAACTTTCAGTAATGGAGAAATGGAGTATCCAGTATATACTGTTGGTGAAAGTGGAACTATGCATCATACTGATCAAACCCATTATTACAGCACAAATTCTTTTTCTCaaaATGTTGACAATGAtcgtactataattattaacactCAAGAAATCAGCCAAAATTCCTTTATATCTTTGgatATGTCATATCATACAGTTAACGCCACTGAGTCTGGTATAACAAACATAAATCAACTGAATAGTATCGAGGAGTCAAATAGAGAAACGCAAAACTCCAGTCTCATCCAAGCAAATAAAATTTCTCCTGCAACTgtcGACTGGCTGATGGATAATTATGAAAAGGCTGAAGGAGTGTCGTTACTTCGATCAAcaatatatgataattatttaacacattGCTCGGAAACTAAATTGGATCCTTTAAATGCCCCATCATTTGGTAAACTTATCCGATCTGTGTTTACGGGATTGCAAACAAGACGTCTAGGAACTCGaggAAATTCCAAATACCATTATTATGGTATTAGAATTAAAcctaattcattattaaatgacTTTAAAGAAGAAGAAAGCCTACCTGTTGAAACAACAAGTCAAAGTagtagttcaaaaaaaaataaaaaaataaaaactgaagaGCAAAATTGCAATCAATATATCACCAATAGTTCAGATTCTGGTAATTATTCTCAAAACAGTATTCCATCTTCTCCTCATGCCCAAGACCAAGAATATTTAGGTGACGGTGCTAATGCTGTACCAGAATTTCCTGATACTAAATTTGATGAGATACTATTGGATGATGATTGTACTTTAGAAGATGTAGATACATTCAAAAATTTGTACCGTGAACATTGTGAAGCATTTTTAAGTGCCGTAATGAACTTAGAATTTGGCACTATTGAGTCACTTTGGCGTCAATTTTGGTGTAGtcaaaattatgaatatgaagGAGGACAATATTtatctaaagaaaaattatattcactGTCAAAGTGCAAAACATTGCAACTGTTTGTGAAAACTGTTGATTTGCTATTTTATCAAAACTTGGTTAAAGTTTTGATTCCAGATGTTCTTCGGCCTGTTCCTAgaACATTAACAGATGCAATTAGAAATTTTTCCAAAAGCCTAGAGGCATGGCTTATATCAGCTATGCAAGGATGTCCAGAAGAAATTAtctcaataaaagTGACTGCTGTTAGAGCTTTTGCACAAACACTACGCAGATACACTACTGCAAGAGCTGTGCTTCAAAATTATACTCAAATAAATCAAATGCTTACTGATTTGAATCGTATGGACTTCCGTAATGTACAACAAgttCAACTTGTAAATAATTTGGGAAGTGAAAATTATGCGGTTCATACCGAAAAAAGAGTTTATAGTAGAATAAATGAAGAGTCGGAAATGCTTTTGGATTTTAATGAATtctccaaaaaaattaaaactcacaattctaCTGCTTCCACAACTCgagaacattttaatattttattacaaaatccatcaaaaaaaactaagaaaaataaatctaagataGCAATAAAAGAAGAAAGCGAGTCGTCAAAAGATGGATCTAAACaagaaaatcttaaaataatggAATATTTGAAAGAAGAAATGTCTGAAGATGATGCAGAAGAGATATTCAATGagaCTGCTACGATTAACGCTCCTTATAATTCAAGAATTTCAGAAGTTCACGAAGAGTATCCTAAATTatttcataaattatcaaaaaaaaaaatgaatcaacAGAAAAAAGTTATTGAGatcatGACTCAAGCGGAAATTATGTCACCGAGAaaatcaaataaacaaaatcaacaGCCGACTTATAAAGACTTTTCGAAAAACAATTTCCCTCAATCAGTGGACATGGATGAGGAAacatatgataataatgatcGTATTGGCGTTgataacgaaaataattttgagttctTCGATGCTCGGGACGATTACAATTCGGAATATCCCACTATGACCGACACAGGCCAGTTTTCTTGTCAATTTTGTGATAAAGAATTTACCAACGCCAATAGTTTATCCAGACACGAAAATGTTCACACTGGAAAAGCTCCTCTTGAGTGTGATGTTTGCTTCAAAACGTTTATCAGCAAAtctatattgtgtatacataaAAGATCACATACCGGAGAGAAACCCTATGGGTGCATCATTTGTGGACGATCATTTACGCAAAAATCGCATTTGGTTTTACATTATAGAACACATAcaggcgaaaaaccgtacgagTGTGGcttgtgtgaaaaaaaattctcatcAACCAGTGGTCGAGCAGAACATACCCGTAGACGTCACCCATACGTTTGA
Protein Sequence
MATSVGSRIKLEGSAGTGSQINIIPVVTADRVGQTLVVQPVQQSFVNVNNNGQLANATLYAASAVHDDGSNKSTDDDEHHLDHKDRKFSTVTVDNDHYIVAKSEGTHGTYYTSLTPVPTLVPKVEPIDYDDVGQSPYVQYVEGIGEQATFSNGEMEYPVYTVGESGTMHHTDQTHYYSTNSFSQNVDNDRTIIINTQEISQNSFISLDMSYHTVNATESGITNINQLNSIEESNRETQNSSLIQANKISPATVDWLMDNYEKAEGVSLLRSTIYDNYLTHCSETKLDPLNAPSFGKLIRSVFTGLQTRRLGTRGNSKYHYYGIRIKPNSLLNDFKEEESLPVETTSQSSSSKKNKKIKTEEQNCNQYITNSSDSGNYSQNSIPSSPHAQDQEYLGDGANAVPEFPDTKFDEILLDDDCTLEDVDTFKNLYREHCEAFLSAVMNLEFGTIESLWRQFWCSQNYEYEGGQYLSKEKLYSLSKCKTLQLFVKTVDLLFYQNLVKVLIPDVLRPVPRTLTDAIRNFSKSLEAWLISAMQGCPEEIISIKVTAVRAFAQTLRRYTTARAVLQNYTQINQMLTDLNRMDFRNVQQVQLVNNLGSENYAVHTEKRVYSRINEESEMLLDFNEFSKKIKTHNSTASTTREHFNILLQNPSKKTKKNKSKIAIKEESESSKDGSKQENLKIMEYLKEEMSEDDAEEIFNETATINAPYNSRISEVHEEYPKLFHKLSKKKMNQQKKVIEIMTQAEIMSPRKSNKQNQQPTYKDFSKNNFPQSVDMDEETYDNNDRIGVDNENNFEFFDARDDYNSEYPTMTDTGQFSCQFCDKEFTNANSLSRHENVHTGKAPLECDVCFKTFISKSILCIHKRSHTGEKPYGCIICGRSFTQKSHLVLHYRTHTGEKPYECGLCEKKFSSTSGRAEHTRRRHPYV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01350330;
90% Identity
iTF_00942236;
80% Identity
iTF_00942236;