Mann014561.3
Basic Information
- Insect
- Macrophya annulata
- Gene Symbol
- -
- Assembly
- GCA_963924015.1
- Location
- OZ001260.1:9108999-9111734[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.78 81 4.6 4.4 1 23 115 138 115 138 0.94 2 14 1.9 1.9e+02 3.4 1.3 2 20 203 218 202 222 0.70 3 14 0.00018 0.019 16.0 2.5 2 23 320 341 319 341 0.96 4 14 0.92 95 4.4 0.3 5 20 432 447 430 449 0.87 5 14 0.29 30 6.0 0.5 1 23 617 639 617 639 0.96 6 14 0.77 80 4.6 0.1 5 23 648 667 646 667 0.93 7 14 0.78 81 4.6 0.1 2 21 672 691 671 692 0.91 8 14 0.0003 0.031 15.4 0.1 1 23 707 730 707 730 0.97 9 14 2 2.1e+02 3.3 1.7 1 13 737 749 737 760 0.80 10 14 0.22 23 6.4 0.6 3 23 766 786 765 786 0.91 11 14 0.00018 0.018 16.1 2.1 2 23 792 814 791 814 0.96 12 14 3.9 4e+02 2.4 3.2 2 23 823 843 822 843 0.89 13 14 0.0035 0.37 12.0 1.1 2 23 848 870 847 870 0.92 14 14 0.00016 0.017 16.2 0.1 2 21 879 898 878 899 0.94
Sequence Information
- Coding Sequence
- atggaatCGTATTCAAACGGGCAGAATCCTTACCGATTAAAAGCTCCTGTCGTCAAACTAGAGAGGTGCGACAAGATATGGAAAACGCTTCAGCTGATAAGAAGCATGCAAGATAAACACCTTGAAGATATTCAAGATTGGATAAAAAGGGAACCAATAACGTCCGAAAAAACTTTAAGGAAACAACCACCGATGACTTACATACCCGATAAATCATTGCCTCTAAATTTAATAGGTGAACCAAATTTGCCAAGACCATACATAAAGTATCACCCAATGTTTAACAATGGTAATGAATCATTGCCACAATTTCAATTGGCTGAAAAAAGTCGCGTTAATTTATATCATTGTGAAATTTGTAGTCAGGAGTATTGCGATTATAAAAGATTTACCGATCACCAAGAACAAGTACATGGAATTTTAATCCCAAAGAAATTGACAGCTAAGAAGGAAAAGGTTCACAATAAAAGTAacattgatttaaaaaataggcGTCATTCAACTGagagtaataataatctacaattgaataagaaattagtaccagatgaaaatattgatctACAAACTATTGTTAAGAATTCTTCACAGCATACTGATAGTATTAGATGTAAATTATGtagtaaatattttaagaatatcaaaaaacaCATGATagattatcataaaattaGGTGTATCGGACTACTGAGCAAAGTAACTGatcagaattcaaattttgatcaaGAACAATCTCTGATAGTACTTGAGTCTGTTGATTATGGTTTGCCAGAAGATGTAGAGCAGACTGCTGagcaaataaaacaaataacatCCCCAGATGTTAATTTTCCTGTTCAGAATACGACAAATGTATCTAAACGGAAACTAAACGTGCCTAATAACGGACTTTGCAAAAAGTTTCGTAGCTCTAGTTCTCGGGAAGAAAAGTCAGATACAAGAATTGAACAGCTATTGAAATGCGAGATTTGTGGCAAAGAATATGCCAATTATAAGACGCTGTGTAAACACAGAGATAGGCACAAGAATCATAACGAAGATAAACAATCTTTGGAAACTAAGAAAAACGGTAATGAGTCTGTTGACCCTGCGTCAACATCTAAAACGAATCtagatatttttgttaaattcacacaagataaagataaagataaggATAATAGTAATATTGGTCATAAAATACCTCGGACTAGATCCAGTTTTACCAAAGAACATAGTAGTTTAGATGCattagaaaacgaaaatttcttatcatcagataaaaaagaacaaacgAGTTTGCCAATAAAATGTGTGTGCGGCAGAACTTTCCGCACAACATCGATTCTTTCCAATCATAAGATGGGTTGTAAATTTGTCAATTGTATGGACATCTGTAAATCTTCCGATACACGAACTGGCAGCGACAGAGATTTAGGGATCAGCATAacgattaagaaaaagaataactcTTATGAAATAGTAAGTAAAGACGGCAGCGATGATGAGCCTATCAAGAATGTTCACAAGATGGAAGAGACTGAAATATGCGAAGAGACTTCAGATTCATCATCAGACAATTCGGACAGCAGCGAGTTTGACGATCAACCGGAAAACCTCGTaccagaaaaatcaaaatacagcGAAAAtcatagaattttgaaattaaaattagtagACGAAGATGTGGATATTGATATTGaagatgaaaatgataatgatattgtATCCAATGAAACTTGCAACACAGTAGCTGAGAATAATAACAGCAGCATTTCTTCTGTGATTAAACAGCAGGTCCCGTTGTTGAGAGTTTTGTGCAAGAAGTTTCTCATTCAACAAGGTATTATGCCTAAAGAAGCGACGTCATACAAGTGTCAGATATGTAAAATATTCCTTGGCAGTATGGAAAGATTGTCAAAGCACACCgaaatacacaaaaaattaatgaaaagatCTTGTGGATGCGGTATAAAATTTACCGATATGAAAACATTTGATGATCACATTGCGGTTGTTCATCCAAAGAATATCACATGTCCGTATTGTTATGAAAAGTATATGAGTATAGCCGGATTAAGCGAGCACTTATGTGTAATTACTCGTGGAGCACCGTACATAGAAACTTTCAACGAAAATTATCCTTGCCCAAATTGTAATATTGCTTTCAATAATATTACCTGGTTAGACAGTCACATGAAGTCCAAACACTTGGATCCAAATTTACCTTTTCAGTGCTATCATTGCTTGAAGAAGTTTCCTGATGAAATAGCACGGAGTTTACACTCGCATGAAAAGCACAATGATATATCGGCGTGTCCTATTTGTAATCAGAAGTTTCAAAGCGTTAAGACTAAACAAAAACACGAAGCGTATCATCGAGGAGTTGGGATCCCGTGTCACATTTGTAAGAAGACTTATCGTTCAAGAAAGAATCAAGTCAATCATGTTAGAACTGTTCACAATGattttagtaataaaaaactgaCATGCCATATTTGTCAGAAAAGCATGAAAATTAGGTCATTTCAGAAGCATGTACTCAAACACAGTAGTAATTTGAAATGTGAAATGTGTGATAAGGTGGTATATGACTTTAGAAATTTAGAAAGCCACATTACTGACTGTCATGGTAACGAAAATTATCCACGTAAGAAGTGTAACACTTGCGGTGTGTCTTTTCCAACTAAAGAACAGTTGGAACTGCATATTATAGTCGAAAAATCTGTGAGAAATGAACACTGCAAAAATGTGTAA
- Protein Sequence
- MESYSNGQNPYRLKAPVVKLERCDKIWKTLQLIRSMQDKHLEDIQDWIKREPITSEKTLRKQPPMTYIPDKSLPLNLIGEPNLPRPYIKYHPMFNNGNESLPQFQLAEKSRVNLYHCEICSQEYCDYKRFTDHQEQVHGILIPKKLTAKKEKVHNKSNIDLKNRRHSTESNNNLQLNKKLVPDENIDLQTIVKNSSQHTDSIRCKLCSKYFKNIKKHMIDYHKIRCIGLLSKVTDQNSNFDQEQSLIVLESVDYGLPEDVEQTAEQIKQITSPDVNFPVQNTTNVSKRKLNVPNNGLCKKFRSSSSREEKSDTRIEQLLKCEICGKEYANYKTLCKHRDRHKNHNEDKQSLETKKNGNESVDPASTSKTNLDIFVKFTQDKDKDKDNSNIGHKIPRTRSSFTKEHSSLDALENENFLSSDKKEQTSLPIKCVCGRTFRTTSILSNHKMGCKFVNCMDICKSSDTRTGSDRDLGISITIKKKNNSYEIVSKDGSDDEPIKNVHKMEETEICEETSDSSSDNSDSSEFDDQPENLVPEKSKYSENHRILKLKLVDEDVDIDIEDENDNDIVSNETCNTVAENNNSSISSVIKQQVPLLRVLCKKFLIQQGIMPKEATSYKCQICKIFLGSMERLSKHTEIHKKLMKRSCGCGIKFTDMKTFDDHIAVVHPKNITCPYCYEKYMSIAGLSEHLCVITRGAPYIETFNENYPCPNCNIAFNNITWLDSHMKSKHLDPNLPFQCYHCLKKFPDEIARSLHSHEKHNDISACPICNQKFQSVKTKQKHEAYHRGVGIPCHICKKTYRSRKNQVNHVRTVHNDFSNKKLTCHICQKSMKIRSFQKHVLKHSSNLKCEMCDKVVYDFRNLESHITDCHGNENYPRKKCNTCGVSFPTKEQLELHIIVEKSVRNEHCKNV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00939076;
- 90% Identity
- iTF_00939076;
- 80% Identity
- -