Basic Information

Insect: Macrophya annulata
Gene Symbol: ttk
Assembly: GCA_963924015.1
Location: OZ001257.1:35777418-35795211[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 5.2e-07 5.4e-05 24.0 1.7 1 23 698 720 698 720 0.98

2 8 1.4e-05 0.0015 19.5 2.6 1 23 726 748 726 748 0.98

3 8 2.4e-06 0.00024 22.0 0.3 2 23 757 778 757 778 0.98

4 8 1.4e-05 0.0015 19.5 0.1 1 23 784 806 784 806 0.98

5 8 2.5e-07 2.6e-05 25.1 3.0 1 23 812 834 812 834 0.98

6 8 5.3e-06 0.00055 20.9 2.1 1 23 840 862 840 862 0.98

7 8 8.9e-05 0.0093 17.0 7.5 1 23 868 890 868 890 0.98

8 8 2.9e-05 0.0031 18.5 1.1 1 21 896 916 896 917 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	5.2e-07	5.4e-05	24.0	1.7	1	23	698	720	698	720	0.98
2	8	1.4e-05	0.0015	19.5	2.6	1	23	726	748	726	748	0.98
3	8	2.4e-06	0.00024	22.0	0.3	2	23	757	778	757	778	0.98
4	8	1.4e-05	0.0015	19.5	0.1	1	23	784	806	784	806	0.98
5	8	2.5e-07	2.6e-05	25.1	3.0	1	23	812	834	812	834	0.98
6	8	5.3e-06	0.00055	20.9	2.1	1	23	840	862	840	862	0.98
7	8	8.9e-05	0.0093	17.0	7.5	1	23	868	890	868	890	0.98
8	8	2.9e-05	0.0031	18.5	1.1	1	21	896	916	896	917	0.94

Sequence Information

Coding Sequence: ATGATGGGAGAACTTATTCGCGTATCCGGGAGAGCTCCGGATGTCGCTGAATTTCTAAGGGAAGCAATGCTATCCCAAAGATTCGCCGACGTTGCTCTGTGCTGTCCCGGTGGCCAAAGGTTCCTTGCTCACCGTCTAGTACTCTCAGCAGCCAGCCCCTACCTTCAAGAGGTGCTACTGGCGCACAGCAGATCAGCAGGACTTTGCGAACCTATAACAGTGATACTGGCCGAAGTTGAAGGTCCAGAATTAGCTGCAATTTTGGGTTTAATCTATACCGGAAATGCGGCTATCGCAAGGCCAAGGTTAGATGCGTTTTTGAGAGCTGCTCAAACTCTTCGCGTCAAGTTACCCCCGTTACCCGAAATGATGACGTGTACAGAAGATTGTAAACCAGAAGATATAAAAGACGTAAAGTTTAACACAACTTATCTACAGTGTGATCAGTATCCTCTTCTTTCGTACAGAGGTTGGTTTCAAGAACACGAGGCGAGCATTGAATCCTACAACTCTTACGATCCCAGGCAAAACCGTGATATCAAATTGCATGATAGTTCTGAGAGCTTGAAGGCCTACCCTCAAGACTCAAAGATCGACCACACTCTCCCAAAAACTACAAATCACGTGGACAATGGCCCATTCAAACCACCGGATAAGATGGAGACATTGCCAAGCACAAGGTATAACTTGCATCCTCAACGTGACATCGACGCGAATCAATTAACGGTCAAGCATCTTGACAATCGACCAATTTCACCGAGGGTGATAGATCCTAAGAAGACAGTTGATGGATGTCAAGAAGCAACGGCGATTAATTTGTGCAAAGTGTCAAAGAACGTCGCTGACCACATACCCCAAACCGAACACGACGGTGGTATACGGGGTTCAAGATTCGAGGACCATCACATGGATGTTCAAGACTCTCTTAACAATGGTTTGGTTAATTATTCAACGCAGAGATCGAGAGTTGAGGCTGATAAACGACCAATTTTGGTGGAGACGGCACCGACGCAAGTAGTACTACCAAGTGACATCAGAAGACCGTCTCCTCTTGATGACAAAGATCGGCTTTCTATATCGACAATTGACCAACGAATTAATACTGAAAGAAATTATGAAGCTCCGAGTAAAATTTTGGAGAGTTTGTTCGATCTCAGGGTACCATCGCTCCATCAAACTACACATACAGAATCATTGACCACAGAGAAGTTCAATTACGTTCAAGGAGAAGTGAACTCGACGTGCAGAGAGAACTGCTGTAGGTGGAGACCACCCAGAAAACACGTTGCAAATCATGTTACGGCATCCCCTTGGCGACAGCTGACAAGACCACACCATGCACCGAAGATGCAACCCATGATGGTGCAGAATCATCACGAAAATTGTGAGCCTAATGGAAGATTGCAGCAACTCTTGTCGACGGATGTAACGCGGATGGAGACAGCAATACCTCCAGGATGTCAGCCCGTTCTAAACGATCAGTTCCCGAGGCCGATCGCAAACTCCGTTTCAGGCTTTCAAGGATTTGAAGTTCCTAACACAACGAATATCGCGTATCCAAGTGAGATGGAGTTACTACGATTAAACGAGAGGAAATTGCAGGAATTCTATAGAGCACAAATGCTATTTCCTGGTCCTCAACCGATCAGACCAGCTCCAGTCAGCTTTGGTGTTAAccagaattattatcaaaaccaAAACTCTCCTCCCACCTTATCACCACCCGGTGTTTCCACAATTCCCAACACTATACCAGGTCATCCAGTTGTTGCCTTACCGATTACCCTGAAAAGTATACAACCCCACCCGACCGTCGAAGTCGGACAAAACTGTCAACCATCGGCTTGTAAACCAGAATTATCACATCCAGTTAGCAGACTTTGTGATTCCACGAGAAGTAGCGAACCTCCGACTAATAATTCAGCGAACTTGACCATCGATGTTGATCAGGAAGAACCACGAATACTTTGCACTCTTGGAGATAAAACCAATAATCCTCTTGCTCAGAGTGATTCAAACAACAACAACCCCTCGGTTACTGATGGAGGCCAAGGACGCAGTGTGACCGGTGCTGGAATCACTACTGATGAACACCGGTGCGAACAGTGTGGAAAAACTTTCGTCACGAGGGCATCTCTGAAGGTTCACGCACGGACGCACTCAGGAGAGAAACCTTTCCAGTGTTCAGACTGCGGGAAGCAGTTCTCCCAGCTACGAAACTACAAGTATCATCGCAGTGTTCATGAAGGTACGAGAGAATTTGCAGCGACCTGTCCTGAGTGTGGAAAATACTTTAATGACAGGGGATACTTGAGTTCGCACATGAAGATCCACCGGAACCGTAAGGAATACGCGTGCGCTGAATGTGGGAAGAGCTTCAATCAGAGAGTTGCTTACAATATGCACGTCAGGATACACACCGGGGTAAAACCACACCAGTGCGAACAATGCGGCAAAgcattttcgagaaaaatgtTATTGAAACAACATCTGAGAACCCACTCCGGCGAGAGACCGTATCAGTGTCAGGTCTGTCACAAGGCTTTCGCTGACAGATCGAACATGACTTTGCACACACGATTACACTCCGGACTTAAGCCTTACCAATGTACCCTGTGCTCTAAGGCGTTTACAAAGAAACACCACCTCAAAACGCATCTCAATTATCACACGGGTACTAAACCATATTCCTGTCCAAATTGTGGTCTCAGGTTTTCCCAGAGTAGCAACATGCGTACACACTTCAAAAAGTGTGCCGTTAACAATCCGAGTTCTAATCAAATTGGAACTAACAACGATAGAATTGCGGGTCAAAGTTCACGGGAAATTGAAGCTCTTACAACATTAAATCGGGTTGGTCCAAGGACACCATCTGCGGCTTTAACACCGCCTAATTCAGACCAGGAATCTAGCGTCTTGACGCCATTATCTTCTAGAAGTTTACCGTCAGAGATGACTAAGACGTAG
Protein Sequence: MMGELIRVSGRAPDVAEFLREAMLSQRFADVALCCPGGQRFLAHRLVLSAASPYLQEVLLAHSRSAGLCEPITVILAEVEGPELAAILGLIYTGNAAIARPRLDAFLRAAQTLRVKLPPLPEMMTCTEDCKPEDIKDVKFNTTYLQCDQYPLLSYRGWFQEHEASIESYNSYDPRQNRDIKLHDSSESLKAYPQDSKIDHTLPKTTNHVDNGPFKPPDKMETLPSTRYNLHPQRDIDANQLTVKHLDNRPISPRVIDPKKTVDGCQEATAINLCKVSKNVADHIPQTEHDGGIRGSRFEDHHMDVQDSLNNGLVNYSTQRSRVEADKRPILVETAPTQVVLPSDIRRPSPLDDKDRLSISTIDQRINTERNYEAPSKILESLFDLRVPSLHQTTHTESLTTEKFNYVQGEVNSTCRENCCRWRPPRKHVANHVTASPWRQLTRPHHAPKMQPMMVQNHHENCEPNGRLQQLLSTDVTRMETAIPPGCQPVLNDQFPRPIANSVSGFQGFEVPNTTNIAYPSEMELLRLNERKLQEFYRAQMLFPGPQPIRPAPVSFGVNQNYYQNQNSPPTLSPPGVSTIPNTIPGHPVVALPITLKSIQPHPTVEVGQNCQPSACKPELSHPVSRLCDSTRSSEPPTNNSANLTIDVDQEEPRILCTLGDKTNNPLAQSDSNNNNPSVTDGGQGRSVTGAGITTDEHRCEQCGKTFVTRASLKVHARTHSGEKPFQCSDCGKQFSQLRNYKYHRSVHEGTREFAATCPECGKYFNDRGYLSSHMKIHRNRKEYACAECGKSFNQRVAYNMHVRIHTGVKPHQCEQCGKAFSRKMLLKQHLRTHSGERPYQCQVCHKAFADRSNMTLHTRLHSGLKPYQCTLCSKAFTKKHHLKTHLNYHTGTKPYSCPNCGLRFSQSSNMRTHFKKCAVNNPSSNQIGTNNDRIAGQSSREIEALTTLNRVGPRTPSAALTPPNSDQESSVLTPLSSRSLPSEMTKT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00939756; iTF_01412486; iTF_01412562; iTF_01411765; iTF_01411680; iTF_01303598; iTF_01303666; iTF_01414418; iTF_01414359; iTF_00938962; iTF_00938898; iTF_01200342; iTF_01200389; iTF_01413629; iTF_01413509;
90% Identity: iTF_01412486;
80% Identity: iTF_00939756;