Basic Information

Insect: Macrophya alboannulata
Gene Symbol: ttk
Assembly: GCA_949628255.1
Location: OX451207.1:12209877-12227092[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 5.4e-07 6.8e-05 24.0 1.7 1 23 744 766 744 766 0.98

2 8 1.3e-05 0.0017 19.6 2.7 1 23 772 794 772 794 0.98

3 8 2.4e-06 0.0003 21.9 0.3 2 23 803 824 803 824 0.98

4 8 1.5e-05 0.0019 19.4 0.1 1 23 830 852 830 852 0.98

5 8 2.5e-07 3.2e-05 25.0 3.0 1 23 858 880 858 880 0.98

6 8 5.4e-06 0.00068 20.8 2.1 1 23 886 908 886 908 0.98

7 8 9.2e-05 0.012 16.9 7.5 1 23 914 936 914 936 0.98

8 8 3e-05 0.0038 18.5 1.1 1 21 942 962 942 963 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	5.4e-07	6.8e-05	24.0	1.7	1	23	744	766	744	766	0.98
2	8	1.3e-05	0.0017	19.6	2.7	1	23	772	794	772	794	0.98
3	8	2.4e-06	0.0003	21.9	0.3	2	23	803	824	803	824	0.98
4	8	1.5e-05	0.0019	19.4	0.1	1	23	830	852	830	852	0.98
5	8	2.5e-07	3.2e-05	25.0	3.0	1	23	858	880	858	880	0.98
6	8	5.4e-06	0.00068	20.8	2.1	1	23	886	908	886	908	0.98
7	8	9.2e-05	0.012	16.9	7.5	1	23	914	936	914	936	0.98
8	8	3e-05	0.0038	18.5	1.1	1	21	942	962	942	963	0.94

Sequence Information

Coding Sequence: ATGATGGGAGAACTCATTCGCGTATCCGGGAGAGCCCCGGATGTCGCTGAATTTCTGAGGGAAGCAATGCTATCCCAAAGATTCGCCGACGTTGCTCTGTGCTGTCCCGGTGGCCAGAGGTTCCTTGCTCACCGTCTAGTACTCTCAGCAGCCAGCCCCTACCTTCAAGAGGTGCTACTGGCGCACAGCAGATCAGCAGGACTTTGCGAACCTATAACAGTGATACTGGCCGAAGTCGAAGGTCCAGAACTAGCTGCGATTTTGGGTTTAATCTATACCGGAAATGCGGCGATCGCAAGGCCGAGGTTAGACGCGTTTTTGAGAGCTGCTCAAGCTCTTCGCGTCAAACTACCCCCGTTACCCGAAATGATGACGTGCACGGAAGACTGTAAACCGGAAGATATAAAAGACGTAAAATTCAACACAACTTATTTACAGTGTGATCAGTACCCTCTTCTTTCGTACAGAGGTTGGTTTCAAGAACACGAGGCGAGCATTGAATCCTACAACTCTTACGATCCCAGGCCAAACCGTGATATCAAATTGCACGATGGTGCTGAGAGCTTGAAGGCCTACCCTCGAGACTCAAAGATCGACCAAACCCTCTCAAAAACCGCAAACCACGTGGATAATGGCACATCCAAACGACCGGATAAAATGGAGACATCGCCAAGCACAAGGTATAACTTGCACCCTCAACGCGAAATTGACGCTAATCAAACAACGGTCGAGCATCTGGACAGTGGACCAATTTCACCGAGGGAGATAGATCCTAAGAAGACGGTTGACGGATGTCAAGAAGCAACGGCGATCGATTTGTGCAAAGTTTCGAGGAACGTCGCTGACCGCATACCCCAAACCGAACTCGACAGTGGTCTACGAGGTTCAAGATTCGAGGATCACCACATGGTTGTTCAAAACTCTCTTAACGATGGTTTGGTCAATTATTCAACGCAGAGATCGAGTGTTGAGGCTGATAAACGACCCATTTTGGCGGAGACGGCACCGTCACAAGTGGTGCTGCCAAGTGACATCAGAAGAACGTCTCCTCATGATGACAAGGATCGGTTTTCCATGTCGACAATGGACCATCGAGTTAATACTGAAAGAAATTATGAAGCTCCGAGCAAAATTTTGGAGAGTTTGTTCGATCTCAGGGTACCATCGCTGCATCAAACTGCACATACAGAATCACTGACCACCGAGAAGTTCAATTACGTTCAAGGAGAAGTGAACACGACGTGCAGAGAGAACTGCTGTAGGTGGAGACCACCCAGAAAACACGTGGCAAATCATGTCACGGCATCCCCTTGGCGACAGCTGACAAGACCACACCATTCACCGAAGATGCAACCCATGATGGTGCAAAATCATCACGAAAATTGTGAATCTAGCGGACGTTTGGTAACCGTGTTAGAAGACCTAGCGAAGGCTGAGTGTAACGCCCCATCTGGCAGCGATAGTTCTTTTCGAATAATTAAGTACGGGATATTGACCAAGGCGACAACCGGGACCTCTAAAACGGAGCCTAATGGAAGATTGCAGCAACTCTTGTCGACGGATGTAACGCGGATGGAGACAGCGATACCTCCGGGATGTCAGCCCGTTCTAAACGATCAGTTCCCGAGGCCGATCGCAAACCCAGTTTCAGGCTTTCAAGGATTCGAAGTTCCTAACACAGCGAATATCGCGTACCCGAGTGAGATCGAGTTACTGCGATTAAACGAGAGGAAATTGCAGGAATTCTATAGAGCACAAATGCTGTTTCCTGGTCCTCAACCGATTATACCGGCTCCAGTCAGCTTCGGAGTCAACcagaattattatcaaaacCAAAACTCTCCTCCCACCCTATCGCCGCCTGGTGTTCCCACACTTCCTAACACTATGGCAGCGCATTCGGTTGTCCCCTCACCGATTACCCTGAAAAGTATACAACCCCACCCGACCGTCGAGATCGGGCAAAACTGCCAGCCACCGCCTTGCAAACCGGAATTATCACATCCGGTTAGCAGACTCTGTGATTCCACGAGAAGTAGCGAACCTCCGGCTAATCATTCGGCGAACTTGACCATCGATGTTGATCTGGAAGAACCGCGAATACTTTGCACTCTGGGAGATAAAACCATCAATCCTCTTGCTCAGAGTGATTCAAACAACAACAACCCCTCGGTTACTGATGGAGGCCAAGGACGCAGTGTGACCGTTGCTGGAATCACTACTGATGAACACCGGTGCGAACAGTGTGGAAAAACTTTCGTCACTAGGGCATCTCTGAAGGTTCACGCACGGACGCACTCAGGCGAGAAACCTTTCCAGTGTACAGACTGCGGGAAGCAGTTCTCCCAGCTAAGAAACTACAAGTATCACCGCAGCGTTCATGAGGGTACGAGAGAATTCGCAGCGACCTGTCCCGAGTGTGGAAAATACTTTAATGACAGGGGATACTTGAGTTCGCACATGAAGATCCACCGGAACCGTAAGGAATACGCGTGCGCTGAATGTGGGAAGAGCTTCAATCAGAGAGTCGCTTACAATATGCACGTCAGGATACACACCGGGGTAAAACCTCACCAGTGCGAACAATGCGGCAAAGcgttttcgagaaaaatgtTATTGAAACAACATCTGAGAACCCACTCCGGCGAGAGACCGTATCAGTGTCAGGTCTGTCACAAGGCTTTCGCCGACAGATCGAACATGACTTTGCACACACGATTACACTCCGGACTTAAGCCTTACCAATGTACTCTGTGCTCTAAGGCGTTCACTAAGAAACACCACCTCAAAACGCATCTCAATTATCACACGGGTACAAAACCGTATTCGTGTCCAAACTGTGGTCTCAGGTTTTCCCAGAGCAGCAACATGCGTACACACTTCAAAAAGTGTGCCGTTAACAATCCGAGTTCTAATCAAATCGGCACTAGCACCGATAGAATCGCAGGTCAAAGTTCACGGGAAATTGAAGCTCTCACAACATTAAATCGAGTTGGTCCAAGGACACCATCTGCGGCTTTAACACCGCCTAATTCGGACCAGGAATCTAGCGTCTTGACGCCGTTATCTTCCAGAAGCTTACCGTCAGAGATGACTAAAACGTAG
Protein Sequence: MMGELIRVSGRAPDVAEFLREAMLSQRFADVALCCPGGQRFLAHRLVLSAASPYLQEVLLAHSRSAGLCEPITVILAEVEGPELAAILGLIYTGNAAIARPRLDAFLRAAQALRVKLPPLPEMMTCTEDCKPEDIKDVKFNTTYLQCDQYPLLSYRGWFQEHEASIESYNSYDPRPNRDIKLHDGAESLKAYPRDSKIDQTLSKTANHVDNGTSKRPDKMETSPSTRYNLHPQREIDANQTTVEHLDSGPISPREIDPKKTVDGCQEATAIDLCKVSRNVADRIPQTELDSGLRGSRFEDHHMVVQNSLNDGLVNYSTQRSSVEADKRPILAETAPSQVVLPSDIRRTSPHDDKDRFSMSTMDHRVNTERNYEAPSKILESLFDLRVPSLHQTAHTESLTTEKFNYVQGEVNTTCRENCCRWRPPRKHVANHVTASPWRQLTRPHHSPKMQPMMVQNHHENCESSGRLVTVLEDLAKAECNAPSGSDSSFRIIKYGILTKATTGTSKTEPNGRLQQLLSTDVTRMETAIPPGCQPVLNDQFPRPIANPVSGFQGFEVPNTANIAYPSEIELLRLNERKLQEFYRAQMLFPGPQPIIPAPVSFGVNQNYYQNQNSPPTLSPPGVPTLPNTMAAHSVVPSPITLKSIQPHPTVEIGQNCQPPPCKPELSHPVSRLCDSTRSSEPPANHSANLTIDVDLEEPRILCTLGDKTINPLAQSDSNNNNPSVTDGGQGRSVTVAGITTDEHRCEQCGKTFVTRASLKVHARTHSGEKPFQCTDCGKQFSQLRNYKYHRSVHEGTREFAATCPECGKYFNDRGYLSSHMKIHRNRKEYACAECGKSFNQRVAYNMHVRIHTGVKPHQCEQCGKAFSRKMLLKQHLRTHSGERPYQCQVCHKAFADRSNMTLHTRLHSGLKPYQCTLCSKAFTKKHHLKTHLNYHTGTKPYSCPNCGLRFSQSSNMRTHFKKCAVNNPSSNQIGTSTDRIAGQSSREIEALTTLNRVGPRTPSAALTPPNSDQESSVLTPLSSRSLPSEMTKT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00939821;
90% Identity: iTF_00938898;
80% Identity: iTF_00938898;