Mann020291.1
Basic Information
- Insect
- Macrophya annulata
- Gene Symbol
- -
- Assembly
- GCA_963924015.1
- Location
- OZ001262.1:576552-579443[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.00059 0.061 14.4 1.4 2 20 151 169 150 172 0.94 2 13 0.00088 0.092 13.9 0.9 1 23 178 201 178 201 0.93 3 13 5.6e-05 0.0058 17.7 2.6 1 23 207 229 207 229 0.98 4 13 6.1e-06 0.00063 20.7 2.2 1 23 380 402 380 402 0.97 5 13 0.013 1.4 10.2 1.0 2 21 412 431 411 432 0.93 6 13 0.00053 0.055 14.6 2.0 1 20 454 473 454 476 0.92 7 13 0.0064 0.67 11.2 0.9 1 23 481 504 481 504 0.95 8 13 2.1e-06 0.00022 22.2 0.1 1 23 510 532 510 532 0.99 9 13 0.001 0.11 13.7 5.4 1 23 539 561 539 561 0.98 10 13 0.00046 0.048 14.8 0.4 3 23 569 589 567 589 0.97 11 13 0.00053 0.055 14.6 0.2 1 23 595 618 595 618 0.96 12 13 0.45 47 5.4 0.2 1 23 632 654 632 654 0.94 13 13 0.00011 0.012 16.7 0.1 2 23 941 962 940 962 0.96
Sequence Information
- Coding Sequence
- ATGGAAGCGCCCGAGAATGAACAGCAATACGTGGCTTTCCCGCTTTCAACAAACATGCACGATTCAATGCAAGAGACAATAATATCACACGAAGAAATATGCGAGCCTGTAGTGGACGATTGCGTATTGTCAGATAGTTTACCCGAGGTAACAGTTAGCGAAGTGGAATCGCGAATAACCGAAGTTCAAGCGGCGGTTGAAATATTAGCATCAAATTCGGACCCAGAAGACGACGACAGTTCGTCGGTATATCCGATATACATAAAACAAGAAGAACAACAGCCGTATACGTCGGGTGACGACGAGTCAATGGCAGTCGAGGCGCTGCGTCAGCTGGGCGGAATGTACCCGTGttttaatgagaaaaaaatatcatgtcCAAATTGCGCTAATTTATTTACCCATATTGAGATGGGTAAACATCATCCAAATTGCGCGGCTGTTAAATTATCATGTACAACATGCGGCgaaagatttgaaagaaaaatcgatttaaataATCACATGGTTTGTCATCAAGTTGACAGACCACACGCTTGTCGAACTTGCGGTaatttattcagatcaaaGGCAAATCTACAATCTCATATGGCCCAAGTACACCAAGCAGAAAGACCCCACAAATGCACTATCTgtaattcgaattttcaaagacCTTCAAGTCTCTCTAATCATATGAAAATTCATACATACGTCGCAGGCAGAGCAATAATGCAAACATCTAACAGCGTTGCTCAACAGACGGTAGAATCTTTCAGAAAATGGCCAGAAAATAGCAGCTCAGATTCACCCAGTACATCCGTACCCTCTTCATCGGTATCTTCCATTCCTAACTATGAAGTATCACAAGTACATTGGTCGATACCGACTTATAATTTTGGCACAGATCAGCCGGCTCTGAGTTCAAATCATCACGATAAAATTGACTCGTTACACGATTTTGCAGTAATGCCAACTGCGGATGTTTCCCAGTTTGAATATGCACAGCAAAACGCTATTAATCATCAGTACAATTTGTCTATGAATTCTGCTTTCAGTGGTCAGGATGGTTTAGTAAAGATCGAATCTCTGCCGTTCGCCAATAACGAGGCTAGGAGTCGTAGCTTTGTTGAGGTCGAATTGAGCGAGGGTAATCAACACACTTGTACTCATTGCGGGGTCAGTTTTTCTAGAGCTTCGTCGCTCGCCTCTCATGAGAAGATACACACTTGCAAGAATTGGAGTATGCCAGTCGAGTGCGAATTTTGCGACAAACAGTTCCAAGACAGCAACTGTTTGGCCACTCATCAAACAACTTGTGCTAAAAAGGTGATGAGAAACAATGCTGAACATGGTATGCCTAATAGTAAATGGGGGAAGCATGCGTGCGCAGATTGCGGGAAGAAATTTACCACCAAACAGAAAATGTTCAGACACCAGTGGATACATAGGAAAAAAACTCACTCCTGCGAAGTATGCGGTGCTCAGTTTGAAAAGCAACATGAATTGGACGAACATAGACTTTCCGCTCATCCTGGGGACTCAGCTTTTACTTGCGGTGAATGTGGGAAGAGTTTTGTCTCCAGACAGGGACTGTGGGAACATGCAAGAACCCACGCTGGCAGTCCAGCTCATTTTCACTGCGATGTTTGTTCCAAGACTTTCTCTTCTAGGCAGGGATATCTCATTCATCACAGAACTCACACAGGAGAAAGACCCTATGGGTGTAAATTTTGCTGGAAAGCATTCAGAGACGGAGGAACGCTAAGGAAACATGAAAGAATTCATACCGGAGAGAGACCACACGTTTGTCCATTATGTTCTAGGGCTTTTAACCAGAAGGTTGTGCTCAGGGAACATGTTAGGTGGGTTCATGCCGCTGGTAAAAATGAGACTGAAGTTACTGGTCCTCCTTTTAGGTGCCCGCTGTGCGGAGCACTGAATCAAGACCGGGATGAGCTGTGTGCTCATATTGTTAAACACTCTGACCAAATGATAGCCGAAGCCAAAGCCAAGACGAACAATAATGCTTCTAAGCCAAAGCCTACTAAGAAAAAATCGAAGGCTGCTTCAAGCTCGGGAACTTCTTCTTCTGGAAAACAGAACACTGGGAGTAGGTCAATTTCTAGAACCGAACAGAACGAAGCTCTGCTTTCTATTTCTGAAACCACGACTAAGACTAACGATAGCTTGCCTCAACTTATGGCTACCAACAAAACCAATGAAGCTTTGCTGCTAATTACATCCGCTAAGCGTAACGAAGCTCTTCGGCTTATATCAGAAGTTAAACAAAACGATTTACACTTGATAACACAGGGGAAACAGCAAGGGGATAATCATCTTCATATTCCGCAAATAAATCATAGAGAATCCCTAAATTTGACTGCTGAAGATAACAACAAACAGGGGTGCGACGTGCGCATGGTTTCTTCGGATCAACAACAAAGTAGCGGAAATTCGCAACAAGGAACTAGGCAGAGCGAAGCCAATAATTCAATGCACTTGATGTCTGGTTCTAAACAAAATAACACCGTACATTTGGTTGAGTCTAGCAAACAAAACAATACTTTGCATCTTATTTCAAAGCAGAATGAATCTTTGCCTGTACTTACTATACCAAATCCACAAAATCATGAAAACTTTTCCAGTCAAATAGCGCATATTAATAACGTCGATATGCCTATGAACATGGTAACTCATCATTCATCTCAACATCACGGTGATAGAACGTCGAAATCCCAAAATTCTGTACAGAAATCATTGATACAAGATAGAGGGTCACAGTCTAATCCTGTACAGGTTCAATATCAACATAGGGAAAGCGACGACGGTGAAGAATCGGTCTGCGGTATGTGCGGTGaagaatttacaaataaaaacttgCTTATGGAACATgttaaaattcatatataa
- Protein Sequence
- MEAPENEQQYVAFPLSTNMHDSMQETIISHEEICEPVVDDCVLSDSLPEVTVSEVESRITEVQAAVEILASNSDPEDDDSSSVYPIYIKQEEQQPYTSGDDESMAVEALRQLGGMYPCFNEKKISCPNCANLFTHIEMGKHHPNCAAVKLSCTTCGERFERKIDLNNHMVCHQVDRPHACRTCGNLFRSKANLQSHMAQVHQAERPHKCTICNSNFQRPSSLSNHMKIHTYVAGRAIMQTSNSVAQQTVESFRKWPENSSSDSPSTSVPSSSVSSIPNYEVSQVHWSIPTYNFGTDQPALSSNHHDKIDSLHDFAVMPTADVSQFEYAQQNAINHQYNLSMNSAFSGQDGLVKIESLPFANNEARSRSFVEVELSEGNQHTCTHCGVSFSRASSLASHEKIHTCKNWSMPVECEFCDKQFQDSNCLATHQTTCAKKVMRNNAEHGMPNSKWGKHACADCGKKFTTKQKMFRHQWIHRKKTHSCEVCGAQFEKQHELDEHRLSAHPGDSAFTCGECGKSFVSRQGLWEHARTHAGSPAHFHCDVCSKTFSSRQGYLIHHRTHTGERPYGCKFCWKAFRDGGTLRKHERIHTGERPHVCPLCSRAFNQKVVLREHVRWVHAAGKNETEVTGPPFRCPLCGALNQDRDELCAHIVKHSDQMIAEAKAKTNNNASKPKPTKKKSKAASSSGTSSSGKQNTGSRSISRTEQNEALLSISETTTKTNDSLPQLMATNKTNEALLLITSAKRNEALRLISEVKQNDLHLITQGKQQGDNHLHIPQINHRESLNLTAEDNNKQGCDVRMVSSDQQQSSGNSQQGTRQSEANNSMHLMSGSKQNNTVHLVESSKQNNTLHLISKQNESLPVLTIPNPQNHENFSSQIAHINNVDMPMNMVTHHSSQHHGDRTSKSQNSVQKSLIQDRGSQSNPVQVQYQHRESDDGEESVCGMCGEEFTNKNLLMEHVKIHI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01200395;
- 90% Identity
- iTF_00938956;
- 80% Identity
- -