Mann010955.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Macrophya annulata
Gene Symbol
-
Assembly
GCA_963924015.1
Location
OZ001259.1:10173264-10176209[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 9.4e-05 0.0098 16.9 0.7 2 23 334 355 333 355 0.97
2 11 0.00037 0.039 15.1 0.7 1 23 363 386 363 386 0.94
3 11 0.00021 0.021 15.9 2.3 2 23 434 455 433 455 0.97
4 11 2.9e-07 3e-05 24.8 0.7 2 23 503 524 502 524 0.97
5 11 0.0012 0.12 13.5 1.4 1 23 529 552 529 552 0.95
6 11 7.5e-06 0.00078 20.4 0.2 1 23 589 611 589 611 0.98
7 11 1e-06 0.00011 23.1 0.9 1 23 621 643 621 643 0.96
8 11 2.9e-06 0.0003 21.7 1.2 1 23 649 671 649 671 0.99
9 11 1.5e-05 0.0015 19.5 0.2 1 23 677 699 677 699 0.98
10 11 0.0025 0.26 12.4 4.2 1 23 705 727 705 727 0.98
11 11 0.00057 0.059 14.5 0.3 1 21 733 753 733 754 0.94

Sequence Information

Coding Sequence
ATGGAAGTGGAAAAGACAGAAGAAGGTGCTGAAATTATTTCCCAAATTCAGTCAACTTCTTACCATGAATGTCGTATCTGTTTAAAGAATTCAAACGAATTTTgggaattatttgaaaacgatGACGATATACCACGGAAAATAATGGCGTTTGCTTCTATACAGaTAGAACATGGAGACGGCTTACCAAGTGTAATTTGTTTCTCTTGTCGCCAGCTACTGGATGTGTCTTACGATTTTAAATGTCAGGTTGAAAGATCCGACGCTTCTTTACGCAAAATATTACTAACAAAAATAGAAGTGAATGAAGATGCTGGTAAAGAGTTATTGTCCCAGTCTGTTAACGATGTTATTACAGAGGCCATTGCCGACGAGATTCCAAATGATCATATAGAAATAAAGGATTTTGAAATGCATAATGAAACTAAGATCCTTACTCTACAAGATATTAAACATGTTGTATTAAGtgattatgataataaacaaGAAATAGTAACTTATGAGATCAATGAGGAATGTGTTAGCGGCAATGAGTCTTTACACGGTGAGGAACCAGAGGAGAAAAACGTCGATGATGAAACAGATGATAAAACTGTAGAAAAAGATGATGATTTAGGTGAGCCAGAGATTATATCGAGTTTGGAGAGCTCTGTTGTATTGTTGGAGAATCAGGGAGTTACGGTGGGCAAATTAATAGACTCAACAGATCAAAGTATGGAATCTGAATCTGAACGAATTAAAGAGGAAGAACTCTTATTACCAGAAGATAGTGATATGTCTGAAGAAGACGAGGATAATCATCAAGCTGAtgagattatttttcacaGTGACGAtcttaaatttgaattgaaaaataattcgccATTAGAAAGAGAGGATGAAGTTGATGAAGCATCCTCTGAATCTAGTAAATTGAAAACTATGAATTGCCAAAATTCTGGTGGAGAAATTAACGACAGTGATGAAGAAAAACCATTGATTTCGAGAACGAGTAGACAAAAATGCCCCCATTGTATCAAAAGCTTTGCAACTAATCTTGCACTGCAAAGACATATGGCAGTTCATAAACACAAGACTAAACTTAGATACGTTTGCTACTTGTGTGACaaacaattttctaatgtAGCTAAACTGAAAAACCATGTATCCAATAATCatgattctttgaaaaatgacaACAAAGTTGATGTTGATAATAAATGCGGTAGAGTGGAAACTGATAGAAAGGTAGACAAGTTGGATAAAGATACTGGTGGCTCAATCGACAAAcaaaaagttgataaaaagaattataaattgaaatgcAAAGTCTGTGCAAAACAGTTCACTTATCAGAAGTCATTTCTTTCTCACATTAAAACCCACCCAGAATACGAAAAATCCGAGACAACAGATAATCATTCCGAACAATTAGAAACGATAGAAGAATCGCTAGAACATCAAAATGATTTGTCTAattctaaaataaatgaatccgatgatgatgatttgcCGCTCGAAGGTCTGCAATGTACTCAGTGTGGCAAACTTTTTGCAACAAAGGGAAATCTAAAAAGACATATTTTAACGCATAGTGGTCTTAGATTCAATTGTTCAACATGCGCAAAGGAGTTTTCACGACTTGATAAACTCAAAGATCATGAGCAGTCTAAACACAAAGAGGAAATATTCGGTCCATCAAGCGACGAAGATGAAGACACAGATAACGAGGGCAAACCAAGCGACAGTACGGAATCTAGAAGAAAGGAAAAGAAATGCAGACCTCATCAATGTGCGATGTGTCCAAAGGCTTTTGCCCAGCCGCAATCATTGGCTAACCACATGGAGCGACACAAACGTGTGAAGGAACCTCAGAAGCGTTTTCTCTGCGAAGTATGCAGCAAGTGTTTTGCCCAAAGTGGATCCCTTGTAGCCCATATGCGAACTCATACCGGGGTCAAACCATATGTGTGTAACGTATGCAGCAGAGCATTTACAAAAAGTACATATTTACAGCTCCATCTGCGTACGCACAGCGGTGAAAAACCCTACATATGCCAATACTGTAGCAGAGCATTTGCCAGAGCTAATACACTGGCTCGACATATAACTATGCATACAGGGGAAGCGAAATATCATTGTCAAATTTGCATGAAATCTTTCAGACGATTGACCTCTTTGAATGAACATACTTATACTCATACTGGTCAGAGGCCATATGCGTGTAAAATTTGCTCTAAGCGATACAATAATGCAGGTTCTTTGTATgcacatacaaaaaaatgtagggCGCAACAATTGTCAGGATCTGCTCCGACTTACACAGTTTCAGTTGACAATCCCAATCATCATGACTCTGGCCCAGTACCACAAATGCTAATTTACACCCAGAGAAAAATTGTCACTAATGAACCGCAGACGACTCAAGGTCCAACACCACAGTTTATGATCACGACTGTACAGAGTCAAAAATCTTTGCCAACTAACATTACTCAGCGTTTTGTTGCAGAggattctcatttttattctattgatGGAAAGCAATTGAAAAATCCTTACTATACAATCTATCCAAACATGTAA
Protein Sequence
MEVEKTEEGAEIISQIQSTSYHECRICLKNSNEFWELFENDDDIPRKIMAFASIQIEHGDGLPSVICFSCRQLLDVSYDFKCQVERSDASLRKILLTKIEVNEDAGKELLSQSVNDVITEAIADEIPNDHIEIKDFEMHNETKILTLQDIKHVVLSDYDNKQEIVTYEINEECVSGNESLHGEEPEEKNVDDETDDKTVEKDDDLGEPEIISSLESSVVLLENQGVTVGKLIDSTDQSMESESERIKEEELLLPEDSDMSEEDEDNHQADEIIFHSDDLKFELKNNSPLEREDEVDEASSESSKLKTMNCQNSGGEINDSDEEKPLISRTSRQKCPHCIKSFATNLALQRHMAVHKHKTKLRYVCYLCDKQFSNVAKLKNHVSNNHDSLKNDNKVDVDNKCGRVETDRKVDKLDKDTGGSIDKQKVDKKNYKLKCKVCAKQFTYQKSFLSHIKTHPEYEKSETTDNHSEQLETIEESLEHQNDLSNSKINESDDDDLPLEGLQCTQCGKLFATKGNLKRHILTHSGLRFNCSTCAKEFSRLDKLKDHEQSKHKEEIFGPSSDEDEDTDNEGKPSDSTESRRKEKKCRPHQCAMCPKAFAQPQSLANHMERHKRVKEPQKRFLCEVCSKCFAQSGSLVAHMRTHTGVKPYVCNVCSRAFTKSTYLQLHLRTHSGEKPYICQYCSRAFARANTLARHITMHTGEAKYHCQICMKSFRRLTSLNEHTYTHTGQRPYACKICSKRYNNAGSLYAHTKKCRAQQLSGSAPTYTVSVDNPNHHDSGPVPQMLIYTQRKIVTNEPQTTQGPTPQFMITTVQSQKSLPTNITQRFVAEDSHFYSIDGKQLKNPYYTIYPNM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01413609;
90% Identity
iTF_01413609;
80% Identity
-