Basic Information

Gene Symbol
-
Assembly
GCA_949628255.1
Location
OX451209.1:5439414-5440836[+]

Transcription Factor Domain

TF Family
zf-LITAF-like
Domain
zf-LITAF-like domain
PFAM
PF10601
TF Group
Zinc-Coordinating Group
Description
Members of this family display a conserved zinc ribbon structure [3] with the motif C-XX-C- separated from the more C-terminal HX-C(P)X-C-X4-G-R motif by a variable region of usually 25-30 (hydrophobic) residues. Although it belongs to one of the zinc finger's fold groups (zinc ribbon), this particular domain was first identified in LPS-induced tumour necrosis alpha factor (LITAF) which is produced in mammalian cells after being challenged with lipopolysaccharide (LPS)[2]. The hydrophobic region probably inserts into the membrane rather than traversing it. Such an insertion brings together the N- and C-terminal C-XX-C motifs to form a compact Zn2+-binding structure [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 0.48 1.8e+03 0.0 0.3 56 63 28 35 23 41 0.79
2 3 3e-09 1.1e-05 26.3 9.8 2 62 88 145 87 150 0.82
3 3 1.5 5.6e+03 -1.5 0.4 11 22 170 181 167 185 0.80

Sequence Information

Coding Sequence
ATGGCGCAATTAGAACCGATCGAACAAAAATACTACGATTATTCGCAAGACGATAATTACGAGGGTTACTATGACAAAAACGATCATCAGTGCAGCTGGTGCGATGGGAACCaagaaaattacgaaaattggGAAGTCGACGAAGACTGCGAAGACCTGGAAGATCTGAAACACTGTCAGCACGttgaaaatcgtaaaaatgtTTACTGGGAGGACAGGgattgtcaaaaaaataaaatcaattcacACATCAGAGGCCAAACTTCGGCGGAAATTCTGTGCCCACATTGCAATTATTATGTCAATGCAGCCATTGAGCCAGGACCGAAGTGGTACATGTCCTTGCTGAGCACGGTCCTGCTGCCATGTTGTCTGTGCTGCATTCCTCACCTCACGGTTATCGGCAAGAAACCAATACACAGCTGTCCTCTTTGTCTGGTGATAATACCGCTGGAGAAATTGGAGGATTTTGAGCAAGGGAAATCATCGAAGAGTTATAGGAAATGTTGCAGATCAACCACTGTTACTAAACTTCATCGTAGCGTCGACGAAGTCATTCTAAAGAACCGAGCATACAATCAGTGA
Protein Sequence
MAQLEPIEQKYYDYSQDDNYEGYYDKNDHQCSWCDGNQENYENWEVDEDCEDLEDLKHCQHVENRKNVYWEDRDCQKNKINSHIRGQTSAEILCPHCNYYVNAAIEPGPKWYMSLLSTVLLPCCLCCIPHLTVIGKKPIHSCPLCLVIIPLEKLEDFEQGKSSKSYRKCCRSTTVTKLHRSVDEVILKNRAYNQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-