Malb016777.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Macrophya alboannulata
Gene Symbol
ZNF236
Assembly
GCA_949628255.1
Location
OX451209.1:2940338-2955966[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 28 2.8e-05 0.0035 18.6 0.5 2 23 185 206 184 206 0.95
2 28 4.4e-05 0.0056 17.9 0.6 1 23 212 234 212 234 0.98
3 28 3.6e-06 0.00045 21.4 0.4 2 23 240 261 240 261 0.98
4 28 0.0092 1.2 10.7 0.2 3 23 269 289 267 289 0.96
5 28 0.00012 0.015 16.5 1.0 2 23 300 321 300 321 0.97
6 28 1.1e-06 0.00014 22.9 1.0 1 23 342 364 342 364 0.99
7 28 8.1e-06 0.001 20.3 0.4 1 20 370 389 370 392 0.94
8 28 0.00013 0.017 16.5 1.1 1 23 398 421 398 421 0.95
9 28 1.9e-05 0.0024 19.1 3.7 1 23 430 453 430 453 0.98
10 28 7e-07 8.9e-05 23.6 1.4 1 23 565 587 565 587 0.99
11 28 2.7e-05 0.0034 18.6 1.1 1 23 593 615 593 615 0.99
12 28 0.0013 0.16 13.4 5.4 1 23 621 643 621 643 0.98
13 28 1.3e-05 0.0017 19.6 1.2 1 23 649 671 649 671 0.97
14 28 0.00042 0.052 14.9 3.6 1 23 726 748 726 748 0.98
15 28 4.3e-06 0.00055 21.1 3.7 1 23 754 776 754 776 0.99
16 28 2.2e-05 0.0028 18.9 1.5 1 23 782 804 782 804 0.98
17 28 0.00013 0.016 16.5 7.2 1 23 810 832 810 832 0.98
18 28 6.6e-05 0.0084 17.4 6.7 1 23 1156 1178 1156 1178 0.99
19 28 0.041 5.2 8.6 0.8 2 23 1202 1223 1201 1223 0.97
20 28 1.6e-05 0.0021 19.3 1.4 1 23 1229 1251 1229 1251 0.98
21 28 0.11 14 7.3 0.3 2 23 1258 1279 1257 1279 0.92
22 28 6.5e-08 8.2e-06 26.9 1.4 2 23 1344 1365 1343 1365 0.98
23 28 0.077 9.7 7.7 8.0 1 23 1371 1393 1371 1393 0.98
24 28 0.00011 0.014 16.7 2.5 1 23 1399 1421 1399 1421 0.98
25 28 0.0017 0.22 12.9 3.7 1 23 1427 1449 1427 1449 0.99
26 28 0.016 2 9.9 1.8 3 23 1649 1669 1649 1669 0.99
27 28 1.5e-05 0.0019 19.4 6.5 1 23 1675 1697 1675 1697 0.98
28 28 3e-06 0.00037 21.6 3.8 1 23 1703 1726 1703 1726 0.96

Sequence Information

Coding Sequence
ATGTTATCGGAGCAAGCTATTCTCGCAGAGCAACTTACAACCAATGCGGAAACTATGCCGCTTGGATTTATCATCTCTGATGATGGACGGACCCTTCTTGCGGTCACAGAGCGTGATGACGGGGTCCTAGAGTTCATGTCTGTACCAGTGACCATCCAGCAAAGTAATATAAGCAACTTAACATCGGCGTCTTTGAAACCAAGCGAAGGAAATCCCATATTCCAAATAACACTTGAAGGAATGACGGGAGATTCTGCAAACCAAGCTACAGCTGCCCTTTTTCAAAGCCAAGGCTATCATAGTCTTCCTGTTGTCTCTGACGACGTAGAATCTTCCTATTCACCAGCTAAAGAAATTCAACTAGATTCTCCTAGTACTGTGCTGTTTACTCCTAGCGGTACGGAAACTAGCATCTTGGAGACtaaaagttttgaaatatttgaggCTCCGGCTCCTTTACCAGCTCCTGCTGCACCTACTATTGTGAGACGGAGCCCTGGCAGACCGAGAAAGGATGGGAGTAGTCCGCCTTCTATTCATACCAATAATCTGAAATGTAAGATATGCGGTAAAGGGTTTAACAGACTGATGTTACTTAGAAGACACGTGGAACAACATGCAGAAGAAAAACCACATCGTTGTCCAAAGTGTCCGGCCTCTTTTAACGTTCCTACTAATTTTACGCTTCATATGGCAACGCACAACATCGGTGAACCAAAGTGTCCAGAATGTGGACGAAAATTTGCTAGAATGGCCAGTCTTAAATCACACATGCTTATGCACGAAAAGgaggaaaatttattctgtacTGAGTGCGAGGACGCTTTTACAACAAAGGCTCAGCTAGATGCTCATTTAAAACTCCACAATGAGAAATGGACCACAGAAGATGTTAGGAAGTGTAAACTCTGTAACAAACAGTTTACTCAACCAGCTCTTTATCGTCTACATATTCGTGACCACTATAGGTTACAAACGAAGTTAGTAAAGCAGACAAAAAAAGGCGTCAAACAGAAGACAATGTACAAATGTAAAATATGTttgaaatcatttcaaaaaccGAGTCAGCTTGTACGCCACATCAGGGTCCATACTGGGGAGAAACCTTTCCAGTGCACAATTTGTCCCCGAGCTTTCACGCAGAAAGGATCCTTGCAGATCCATATGTGGAAGCACAATGGGTTTAGACCGCATAATTGCAGTTCTTGCAACGCAAAATTTAGTCAAAAAGGTAATTTAAACGCGCATATATTACGAGTGCATAATGTACCGGATGGAAAACCTTATTACAAATGCACGTATTGTCCGTGTACCTTTAAAAAACTTGGAAGTCTTAATGcacatatgaaaaaaatgcaTTCAAATCCAGTCAAGAAACCACAAAATTGCGACAGTTCTACTGAAGACATGCAAGCCACAGTTGATACAGTAATGTCTCAACTAGCCATGCTTGAATCTAGTGTTAAAAATCCAGCAGATTCTACTGCAAAAAATGCTTCTAATAAAGACATCCTGCAACAAGCTTTAAAGAATAGTGGATTACCTAGCAAAGACAAGGAGTCAGCCTCAGGACAAGTTCCAAAAAAGGGAGAAGCACATACCACTATGGTCACATTATTAGACAGCAGTATAGACAGTGCTACAAGAAAATACGTTACCATAAAACAACGCACTATAGGAAATATTAGATGGTATACATGTTCCTATTGCTacaaagaattcaaaaaaccatCCGATCTTATACGACATTTACGTATTCATACACAGGAGAAACCATTCAAgTGCTCGTATTGTTCCCGATCTTTTGCTGTAAAATCGACGATGATAGCTCACGAAAGAACGCATacaggagtgaaaaaatacatGTGCAGTAACTGCAATAAAATGTTTGCCTGCCATAGCAGTCTAACAACACACATGAGGGTTCATGCAGGAGTAAAGCCTTTTGCTTGCAGTTTATGTGACAAAACTTTCACAGCAAACACCCTCCTAAAAACTCATATGAAATCACACGCTAAAGGAAAGACAAAAGCCAGTCCCGAAGCAGAAGTTCTTGCACCATCTATAGTACTTGAGGAACCGTTAATTATAACTGATGCAGGGAATAAGATCAGCATTGCTCAAGTACAATCAAAACATCAGCAAGTTTATAACAGCAATGATGTTGCCAGACCTCATAAATGTTGGGTCTGCCCTGCTGcatttagaaaaattagtCACTTGAAGCAACATTATCGAAGGCATACAGGAGAAAGGCCATACAAGTGCCAAAAATGCAACAGAAGGTTTACTTCGAACAGTGTCTTGAAATCTCATCTGCGGACACACGAGGGATCAAGACCTTACAATTGTTCAATGTGTAATGCTAAATTTTCAACTCAAAGCAGTATGAAACGACATCTAGCTACTCACAGTAATAAGAGACCGTTTATGTGCCCCTATTGTCATAAAACGTTCAAGACTTCTGTTAATTGTAGAAAACATATGAAGATACATAAGCACGAGCTTGCGCAACAGCAATTGCATCAACAACAGTCTCAACAGCAACAGCCAACTGATCTTGAGGATAAACCAGGGATTACAGTATTGTCTGAAAATATTAATCTAACTGATGAAATGGAAGTTACATTTCAGCCGCAAATGGCACCTGATTTTACACAAGCATTCTCGGATCAGTTTCATACGATTCCAGTTGAAAAGGATAAAACATTGTTGcctgaaaataatacaatagaAACCATTGATAATCaaaCATTACCAGCTGTTGAACCTATTAACCTCGGATCATCCCAAACCCTTCATGCAGACGAGACGGGGACAATAACACTACCTAATTATTCTGGAGATCAAACACTGACACcgGAAAGTATAcgagaaattgaagaaacatTGAACGAGCAGCTATTCAATATTGGCATGAATTTTGGCCTGGGAACTAATTTGACAAGGCAAATGAACGAGACTACTCCCAACACTTTAGAACAGCGAGAACAGCCTAtcttgaatattatttatgaaaatacaAAGAACATAGATACCCCAGCAAATGCTACAATGAATACTGGGATATTTTCACCTCAATTTGACTCTTTTGATATGAGTCACATCACACTGCAGGCAGATAACGAGATGGACATTGGAATAACTCCAGCAAATTCTACAAGTATGGCAAGCATATTGCCCAGATCAGCTCAGGAAGAGCAGCACTTGGTATCAGTTACTACAACGACTTCAATGCCAGAGGATAATCAATCGAAACAACCAAGGCATCTGATGGTTGTAAGTTCAATGCAATCCTGTCCTGAATTATCTCGCCCAGTTCAGGCTTGTCCAAAATATCCAAAAGTAATTGCGAAAGCAGATACGACGGAAGGATTGGATATCCAATCATCTGAAGAAACGATAAAGGAAAATATCAAGTCTGAATCTATACTTTTGCAAGATAAACCAGCGCAAACTCTGTCCTACCAATGCAAAATctgtgataaatattttcataaacaaTCTCAGTTGAGAACTCATAAGAAGACTCATGCCTTAGCGACGCAGGTAAAACCTCTTGACATTGAACTTTCTCCTGTAAACGAATCGGACAGTCTATTGCAATGCCATATGTGCAATAAATCAGGACTTACAGCTATCGCCCTAAAGGATCATCTCAAAACGCATAGAGGAACTAAGGAATTTCAGTGCACAGAATGTCCTTTGAAGTTTTGCACTAATGGAGGACTTAGCAGGCatattaaaatacataataataaagtACAATGGAAATGTACAGCGTGTGATCTAacgtttcaaaataaaatccaaTTATCAATTCACGAAGAATTCCATCAGAATAATACTAATTTGAATACGGTGGAACCCGACAGTTCCCAAAAGGATCCATTAACAATAGATGGCAACTATTTGACACATTCTGAGACACGATTAGAAAACGGTACTAATGTATCTGAAAAAGTTCTTATGGATGCTGTGGCTGAGAAGGAGACAGAtataaaaaaggagaagaaaatatatacaaacaaATGTAAATACTGTCCAAAGACTTTTCGAAAACCAAGCGATCTCGTAAGACATATCAGAACCCATACAGGAGAGAGACCCTATCAGTGCGAATATTGTAACAAATGTTTTGCAGTTAAATGTACATTGGATTGTCATATGAAAGTACATACCggtaaaaaaactttttcatgcCACGTTTGTAACAGCCTATTCACAACCAAAGGGAGTCTTAAAGTCCACATGAGGTTGCATACAGGTTCCAAACCGTTCAAATGTTCATCCTGCGACTTACGATTCCGAACTTCTGGGCATAGGAAAGTACACTTATTAACCCACATGAGAGAGCACAAGGATCCATCAAAGCCTAAACCAAAGCCTCGTAAAGTTGCTGCCATTGCTGGAGTAGCTGCTGAATTAGAAAGGACCGTTGAAAATGCAGTTAATTCTGATACAACAGTTCATCAGCCTGGAGAATATCCAAATATCGATTCAATTACGATTGATACTAATACGCTAGCGGATAACATCACTCCACACATTACTTTTAATGCTGACGGGACCATCCTTAACAACAATGCTATGCTATCTATAAACGTGAGCCATCAGCTTGTTGCCAATCTGCAATATCTCCTCGCTAATGGACTCGTTACGATTCAGACTGACGATGCTCTTCTACAGCAGCTACCTGATGctgattcaaatcaaatagaGCAAACAGAATCGTTGATTACTGCCACTGATATAAACGGCTCAGATCCTCAGGTGGTTTTGTATGAAGCGGAAGGTATGCCAAATGCAGATACAGAGTCCCATGGAACCTTGGAGCTTGATCATTGCATGGAAATGGGAAGTACTGATGAAATAGCATCGTTGTCTGACATTGAAGAGAGCAAGACTAAACTTACGATAGataaaaatcagttcagaagaGGTTGCGATATTTGTGGGAAAACTTTTCTTAAACCGTGTCAAGTTGAACGACACAAGAGGATACACACGGGTGAAAGACCatataaatgtaatttgtgTTCTAAATCATTTACGCAAAAGAGTACTTTGAAAATGCATCAGAAACATCATACCGGAGACAGACCACATCCATGTCCACATtgcgatttttcatttactcaAAAAGGAAATTTAAAGACACATCTAAAACGCGTTCATCAATTGGATACTTTAGAGATAAAGAAACTACGTAGAGGACAACACGTGCTTAGTGCTAAATTTACACAAGATAATTTAGATGAGACTAGAATAATTGGCTTAGAAGATATTGCATTTGCTAATATTCCTTGA
Protein Sequence
MLSEQAILAEQLTTNAETMPLGFIISDDGRTLLAVTERDDGVLEFMSVPVTIQQSNISNLTSASLKPSEGNPIFQITLEGMTGDSANQATAALFQSQGYHSLPVVSDDVESSYSPAKEIQLDSPSTVLFTPSGTETSILETKSFEIFEAPAPLPAPAAPTIVRRSPGRPRKDGSSPPSIHTNNLKCKICGKGFNRLMLLRRHVEQHAEEKPHRCPKCPASFNVPTNFTLHMATHNIGEPKCPECGRKFARMASLKSHMLMHEKEENLFCTECEDAFTTKAQLDAHLKLHNEKWTTEDVRKCKLCNKQFTQPALYRLHIRDHYRLQTKLVKQTKKGVKQKTMYKCKICLKSFQKPSQLVRHIRVHTGEKPFQCTICPRAFTQKGSLQIHMWKHNGFRPHNCSSCNAKFSQKGNLNAHILRVHNVPDGKPYYKCTYCPCTFKKLGSLNAHMKKMHSNPVKKPQNCDSSTEDMQATVDTVMSQLAMLESSVKNPADSTAKNASNKDILQQALKNSGLPSKDKESASGQVPKKGEAHTTMVTLLDSSIDSATRKYVTIKQRTIGNIRWYTCSYCYKEFKKPSDLIRHLRIHTQEKPFKCSYCSRSFAVKSTMIAHERTHTGVKKYMCSNCNKMFACHSSLTTHMRVHAGVKPFACSLCDKTFTANTLLKTHMKSHAKGKTKASPEAEVLAPSIVLEEPLIITDAGNKISIAQVQSKHQQVYNSNDVARPHKCWVCPAAFRKISHLKQHYRRHTGERPYKCQKCNRRFTSNSVLKSHLRTHEGSRPYNCSMCNAKFSTQSSMKRHLATHSNKRPFMCPYCHKTFKTSVNCRKHMKIHKHELAQQQLHQQQSQQQQPTDLEDKPGITVLSENINLTDEMEVTFQPQMAPDFTQAFSDQFHTIPVEKDKTLLPENNTIETIDNQTLPAVEPINLGSSQTLHADETGTITLPNYSGDQTLTPESIREIEETLNEQLFNIGMNFGLGTNLTRQMNETTPNTLEQREQPILNIIYENTKNIDTPANATMNTGIFSPQFDSFDMSHITLQADNEMDIGITPANSTSMASILPRSAQEEQHLVSVTTTTSMPEDNQSKQPRHLMVVSSMQSCPELSRPVQACPKYPKVIAKADTTEGLDIQSSEETIKENIKSESILLQDKPAQTLSYQCKICDKYFHKQSQLRTHKKTHALATQVKPLDIELSPVNESDSLLQCHMCNKSGLTAIALKDHLKTHRGTKEFQCTECPLKFCTNGGLSRHIKIHNNKVQWKCTACDLTFQNKIQLSIHEEFHQNNTNLNTVEPDSSQKDPLTIDGNYLTHSETRLENGTNVSEKVLMDAVAEKETDIKKEKKIYTNKCKYCPKTFRKPSDLVRHIRTHTGERPYQCEYCNKCFAVKCTLDCHMKVHTGKKTFSCHVCNSLFTTKGSLKVHMRLHTGSKPFKCSSCDLRFRTSGHRKVHLLTHMREHKDPSKPKPKPRKVAAIAGVAAELERTVENAVNSDTTVHQPGEYPNIDSITIDTNTLADNITPHITFNADGTILNNNAMLSINVSHQLVANLQYLLANGLVTIQTDDALLQQLPDADSNQIEQTESLITATDINGSDPQVVLYEAEGMPNADTESHGTLELDHCMEMGSTDEIASLSDIEESKTKLTIDKNQFRRGCDICGKTFLKPCQVERHKRIHTGERPYKCNLCSKSFTQKSTLKMHQKHHTGDRPHPCPHCDFSFTQKGNLKTHLKRVHQLDTLEIKKLRRGQHVLSAKFTQDNLDETRIIGLEDIAFANIP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01414380;
90% Identity
iTF_01413599;
80% Identity
-