Mrus015072.1
Basic Information
- Insect
- Machimus rusticus
- Gene Symbol
- Aef1
- Assembly
- GCA_951509405.1
- Location
- OX608050.1:48630121-48630555[+]
Transcription Factor Domain
- TF Family
- zf-GAGA
- Domain
- zf-GAGA domain
- PFAM
- PF09237
- TF Group
- Zinc-Coordinating Group
- Description
- Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 0.0084 91 4.5 0.2 22 49 17 44 12 47 0.85 2 4 7.1e-06 0.076 14.4 0.1 21 51 44 74 41 75 0.88 3 4 0.0021 23 6.4 0.0 21 51 72 102 69 103 0.87 4 4 6.9e-05 0.74 11.2 0.1 21 47 100 126 97 131 0.89
Sequence Information
- Coding Sequence
- ATGTCTCGTGCATTGAGTCGTACAATGACTGTAGCCAACGGCCCCGTAGACAAGCCTTTTCAATGCAACGTGTGTGAAAGGCGATTTCGCCAGCTGAGCACATTGACAAACCATGTGAAAATTCACACTGGTGAGAAACCCTATAAATGTACAATATGCGAGAAGCACTTCCGGCAATCCAGCACCCTAACGAATCATCTGAAAATACATACTGGTGAAAAACCTTTCAACTGCACCTACTGTGGCAAGCAGTTTCGTCAGTTGAGCACACTCACGAATCACCTTAAGATTCACACGGGGGAAAAGCCATTCGAGTGTGCCGTatgcaaaaaacaatttcggCAATCGAGCACACTGAACAATCACATAAAAATCCACGTTATGGACAAACTCTACATACCTTTCGAAATAAAGGCTGAAGAGGAGGAGGGCTGA
- Protein Sequence
- MSRALSRTMTVANGPVDKPFQCNVCERRFRQLSTLTNHVKIHTGEKPYKCTICEKHFRQSSTLTNHLKIHTGEKPFNCTYCGKQFRQLSTLTNHLKIHTGEKPFECAVCKKQFRQSSTLNNHIKIHVMDKLYIPFEIKAEEEEG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00203877;
- 90% Identity
- iTF_01540912;
- 80% Identity
- iTF_01461411;