Basic Information

Insect: Machimus rusticus
Gene Symbol: Rreb1
Assembly: GCA_951509405.1
Location: OX608051.1:309707-315419[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.0047 0.87 11.4 0.6 1 21 167 187 167 189 0.96

2 14 0.0013 0.25 13.1 0.1 1 23 199 221 199 221 0.98

3 14 1.8e-05 0.0033 19.0 7.5 1 23 227 249 227 249 0.98

4 14 0.048 8.9 8.2 0.6 2 20 396 414 396 416 0.93

5 14 1.2 2.2e+02 3.8 0.3 1 20 459 478 459 480 0.76

6 14 0.0071 1.3 10.8 0.1 1 23 614 636 614 636 0.97

7 14 2.4e-05 0.0045 18.6 0.9 1 23 645 667 645 667 0.99

8 14 0.00062 0.12 14.1 2.0 1 23 673 696 673 696 0.97

9 14 0.00072 0.13 13.9 2.1 1 23 1021 1044 1021 1044 0.95

10 14 6.5e-05 0.012 17.2 0.3 2 23 1335 1356 1334 1356 0.97

11 14 0.11 20 7.1 6.3 1 23 1362 1385 1362 1385 0.97

12 14 2.6 4.9e+02 2.7 7.3 1 23 1444 1466 1444 1467 0.95

13 14 0.0063 1.2 11.0 0.5 3 23 1514 1534 1512 1534 0.96

14 14 0.0011 0.2 13.4 4.8 1 23 1540 1562 1540 1562 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.0047	0.87	11.4	0.6	1	21	167	187	167	189	0.96
2	14	0.0013	0.25	13.1	0.1	1	23	199	221	199	221	0.98
3	14	1.8e-05	0.0033	19.0	7.5	1	23	227	249	227	249	0.98
4	14	0.048	8.9	8.2	0.6	2	20	396	414	396	416	0.93
5	14	1.2	2.2e+02	3.8	0.3	1	20	459	478	459	480	0.76
6	14	0.0071	1.3	10.8	0.1	1	23	614	636	614	636	0.97
7	14	2.4e-05	0.0045	18.6	0.9	1	23	645	667	645	667	0.99
8	14	0.00062	0.12	14.1	2.0	1	23	673	696	673	696	0.97
9	14	0.00072	0.13	13.9	2.1	1	23	1021	1044	1021	1044	0.95
10	14	6.5e-05	0.012	17.2	0.3	2	23	1335	1356	1334	1356	0.97
11	14	0.11	20	7.1	6.3	1	23	1362	1385	1362	1385	0.97
12	14	2.6	4.9e+02	2.7	7.3	1	23	1444	1466	1444	1467	0.95
13	14	0.0063	1.2	11.0	0.5	3	23	1514	1534	1512	1534	0.96
14	14	0.0011	0.2	13.4	4.8	1	23	1540	1562	1540	1562	0.99

Sequence Information

Coding Sequence: atgattaagaCGAGTAATGCACAAATCAAAGTGGAACAGAAGATGGAGAGACGCGTATCATCGACATCCGAGTCGTCGCTAGAGCCGATGGACCTCGGGAGGACCCCTAAAAAGTCGATTAGGACAAACGAGTCAGCAACGATGTCCCCGGCAAAAACGGACTCAGTGAACAACGACTCAGAGACGTACGAATCAGACAACGACGACTTCGCCAATCGAATCAATTGCGAGAGGCATGTCGAAATCGAGCCCAGCGAGAATCCCCATTCGCTGCGCAAAAAATTTCGAATCAGCACACCGAACAGGAACAACAATAGCCtgaccaaaaataataataacaataacaacaataaCAGTGTTGTGGCGTACTCGTCTTCGAAGGCTGGCAACGATACGACACAATCGACAAACAACGAATCGGGCTTTGTGGATGCCAGCAGCCATCATTTAAACTCTAGTCCAGAATGCGCTTCGGAACGCGACAGGGAGGACATGAAATACGTCTGCCCCATTTGCGAGGCGGTCTCAGCTACACCTCATGAATTTACAAATCACATTCGGTGTCACAACTATTCTTCAGGAGACTCTGAGAATTTTACATGCCGCATTTGCTTAAAGGTCCTGTCGTCAGCGTCATCGCTGGACCGGCATGTGTTGGTCCACACCGGGGAGCGCCCGTTCAACTGCAAATATTGCCACCTGACCTTCACGACGAACGGCAACATGCACCGACACATGCGCACCCACAAGCAACACCAGCAACAGCGTACCACTGGATCGGGGGGTGGAAGTGCGGGTAGCGGTGGGGGCGGGGGTGGTAGCGGGGGTGGCAGCAGCGGCAGCAGTAGCACCAGCAGCAACTGCGGTCCGAGCAGCGGCAGCAGCGGCGGGGGCGGCGATGGCGAAAGTTATGAAAGCGACGGTTGCTCAACGGACTCAAACGCAAGCAgctcaaataataacaataataataacaataacaactACAAGAGAAAGAGCACGGACGACGACAACGGAATCATAAAGAGGCGCATCAAGACGATAAACAACAACATAATCGATGAGAACGAGACGGAGCCCCAGGTCGGACACAAGTTCTGCTGCCCCATGTGTAGTCGGAGCgatttcataaatatgctCGCCCTAAGTGGCCACATGGATCGCGAGCACCCAGGCCACCCGCCTAAATGCAGACAGTGCGAAATCGTCTTTAAGACACCGAGGGCCCTCAATGGGCACAGGTGTGCCAGCAAAATGAACGTAACCCAGGGTTTCAGGGACATCGACTTTGTGGACTTTTCCAGTGAAAAGTTCCCACTAATAGCGAAGTCTCTTTGCGAGCAAACGATGCGGACACCGATCACAAGTCAGAAGTTCGAGTGCCCAAAATGCTACCGCGCCTTCCCGTGTGCCAGCGCTGTTGATATTCACATTAAAGACTGCGGGGAATCCCCGCAGGACTATTCAATGCGGAAACGTGCCACTAGCGAGAGCTCCGACGAGGAGAATCGACGTGATGAATTTTTTGCTCACTTAGACCTTCAAAACAAGTCTGCTATGAGTTTGGCCAGTTCGATGTCATCGCCACGAACCTCTGAGAAGTCAGACGTGAAAACAGATCTAGAGAAAAGCCCACAGTTCAGCTACAAGCAGCAGGAGTCAAGAGATTTGGCCGATATACAGTCCATGCTCAATGTTACATCCACGCCCAGcagttttataagaaatttcgaaaattacgTAAATGCTCCAAGCAGTGAACACGGCTACGGAAAGGACGAAGAAGAGGCTCAAGATGCTTTCACTTCCGAGTTccgaaaaatgaaattgcgcGGGGAGTTCCCCTGCAAACTTTGTTCAGCAGTTTTCCCAAACTTGCGAGCACTAAAAGGGCACAATCGCATTCATTTAAGTGCAGCTGGAGCTGGACCATATCGGTGCAATATGTGCCCTTATTCCATTCATGACAAAGCCGCTTTAATTCGTCATATGCGCACTCACAACGGCGATAGGCCTTATGAGTGCGCTGTATGCAATTACGCGTTTACAACAAAAGCGAACTGCGAAAGGCACCTCAGAAATAGACACGCTAAAACGACTAGAGAGGAGGTGAAACGTGCCATTATTTATCACCCATCGGAGGACTCTAGCTGCGAAGATCCGATTAAGAAAATGCATCTCTTTTCGTCACCTGAATTCGATCAAGACGAGGAACAATGTGCGCCAAAAGATCGGTCCACACCCTTGTCTCACTTAAAAGAGATGTTGCAGTCAGAGAAGCCCCTCAAGATACAGGTAAAAAGTTTGGAGAAATTAATAGACAAAAGTTATAAGAATTACGAAGAGGCTGAGAAAAGATCTGGCGAGCAAGAGGAGAACAATGACTCCAACCGCCCTATAGACCTCAGCATGGACGTCCTTGACTTAAGTAAAAAGGCCAAGCCAAATCCACCCTCTGAGGAGAAAGTGGAGCTCGAAGCTCCTTCCGAAGCTACCCCAAAGGTAGACATGTCCACTATAGAGaaaaataaccaaattttgCTGGCCCAACAGCAATTCATCAACGAAGCCCTACCCAAGATGGACCCGTCCCAGTACTTCCAGTTGTCGCAACTTTACCGTAACTTTATGTTCTCTCCTTTACACCCATTTTTTCTCCCCAACGGTCTGATGCCAAACAATATAAATGATCTCAATAAATTCACCCCCAACTTACTTATGAACTCAATGTTCAATGGTGACCACAGAGCGCCGCAAACGAGCCCTGCAGCCGCTTCCAGTCAGTGCCAGCCATCACCCCATAGTCAGCAAGTTCCGGTCAGTACCATCGAAAATTCCCTGCTAAAAGGAAGTCCTGCGAGTGCGCAACTATTGCAAAAGTCAATGCAACCCACATCTCCGCAAATCAACATCCCTCGCCACCCGCACCTGGGCCAGCCCCCTCCACAGCAGCCGACTTTGGTCCCGCCTAGTCAAAACACGGGTCCTGTAAAAATGGTCATCAAAAATGGGGTGCTGATGCCAAAGCAGAAGCAGAGGCGGTACAGGACAGAGCGTCCGTTCGCCTGCGAGCACTGCTCCGCTCGATTCACTTTGAGATCGAACATGGAGCGCCACATCAAACAGCAGCACCCTCAGTACTGGGCGCAGAGGCAGAGGAGCGGCCACCACATTATGCGAAGAAGTACAAACTCAGCAGCTATGCCGCAGATATCGTCAAGCACCCTACCCCCCTCGGTGCCCAGCATCCCAACGACTCATTTCAATGCAATATCAGACCAGGTCAAGTACGCCATCCTCGCCCAGCAGTTGAAGACCAGGAAGGACACAGACATTTTGCAGCAGACCCTCTCTCAGGGAAGTAGCAGTAGTCACGGAAACAGCGGAGTGTTCAACAGTACAAACAACCAAACCAGCAACGCTCACTCAAATGTTGAAGATGATGATCCAAAGTTGGTGATAGATGAGGATGAAGAGGTTGAAAATGATGACATCCCTGAGGATGAGACGAAACCTGAGGATTTATCAAAAAACACTGATGCAACCCCTTCAGAAAATTCAGCAGCTAAGAAAGTGGCAGACTCTATTCTAGAACAGGCAATTCGAGCAAGTGCAAACTCAATCAAGAACTCCACCCCCCCAAAATGCTCTGAAGAGCGGGAAACTAAAGATTTTGGTTTGAAGATTGCGAGCAATATGATTGCCCGTGCAGAATCCGTGGGTAAGTACCTAAAAGAAGTAGCTAGCTCCCCTTTCAAAGACGAGTCCTCAGACCTAGCCTCAGTCTCGAAGCTGGTCGATAACGCCACCAACTCGATGTCTTTCAACAACTACTTCAGACCGAGTGATTTACCCAACCAAATGGAGCAAAGTGATGAGGAGGGACTTGTGGCTTCCGGCAGCGCTTCCGAGAGCAATAACTCTGGTACAGAAGAGACCCACAGCACGATTGGGCAAGATCAGAAAAAAAAGTCCGCCTACAGCTTGGCTCCAAATCGGGTTTCTTGCCCGTACTGCCAGCGGATGTTCCCCTGGTCCAGCTCCTTGCGGCGCCACATTTTAACTCATACTGGTCAAAAGCCGTTCAAGTGCTCGCACTGTCCCCTTCTTTTTACGACAAAAAGCAATTGCGACCGGCACCTGCTGAGGAAGCACGGAAACGTGGAATCAGCTGTATCACTGTACGTTCCTATTGAAGACATTCCAGACCCTGTTCCTACTCCTAAAGCCGTCGAGGAGCCCGAAAATAAATCGGCGAACTCCTTGAACGTGAACCTCAACGTGCCCAACATCAAGCCAGAGCCGATGATTTCGTCGTCAGACCTTCCGTTCAAGTGCCACCTCTGCGACGGTTCGTTTTCAGAGAGGATCCACTGCTTGGATCACATCAAAATCCATCACGCTCAAGAGTTTGCCTTACTCCTCGCCAAGGGTGCAATTGACGCCGACGCGGACTACAACCACGTCCAAATGGCGGACGACGACGAGCGCAACGACGGGCGCGGAAAATACCCCGACTATGCAAATCGGAAGGTGATCTGTGCGTTTTGCGTGCGCCGTTTTTGGTCCACAGAAGACCTCAGGCGGCACATGCGCACCCACTCCGGGGAACGGCCCTTCCAGTGCGATATCTGTCTCAGGAAGTTCACGCTGAAGCACAGCATGCTGCGCCACATGAAGAAGCACAGCGGGAGCCACCACAACAGCCAGTCGAACGCAACGAACAGCGGCTCGGACATGTCCGACGACGAGCAGCCCTCCAGCATGATTCTGAGCAACTACCGCACCCACAAGATCCAGGAAATCCTCAGCAAAGCCGAGGCTCTGAGGAAGAGCCACCTCACCGGCGAGCAGAAGGACCTCATCGCGATGCACCCGTTCGTGAAGTCCGAGGGGAACGGCGAGGACAACAACTCCGACCTGATCGGAAATCTGCTGGGCATCAGCGACCAGGGCATTCTCAACAAGCTCCTCTCGTCGGCGGACGAGGCGGCCAAGCTGCTGGGCGTCGAGAAGTAA
Protein Sequence: MIKTSNAQIKVEQKMERRVSSTSESSLEPMDLGRTPKKSIRTNESATMSPAKTDSVNNDSETYESDNDDFANRINCERHVEIEPSENPHSLRKKFRISTPNRNNNSLTKNNNNNNNNNSVVAYSSSKAGNDTTQSTNNESGFVDASSHHLNSSPECASERDREDMKYVCPICEAVSATPHEFTNHIRCHNYSSGDSENFTCRICLKVLSSASSLDRHVLVHTGERPFNCKYCHLTFTTNGNMHRHMRTHKQHQQQRTTGSGGGSAGSGGGGGGSGGGSSGSSSTSSNCGPSSGSSGGGGDGESYESDGCSTDSNASSSNNNNNNNNNNYKRKSTDDDNGIIKRRIKTINNNIIDENETEPQVGHKFCCPMCSRSDFINMLALSGHMDREHPGHPPKCRQCEIVFKTPRALNGHRCASKMNVTQGFRDIDFVDFSSEKFPLIAKSLCEQTMRTPITSQKFECPKCYRAFPCASAVDIHIKDCGESPQDYSMRKRATSESSDEENRRDEFFAHLDLQNKSAMSLASSMSSPRTSEKSDVKTDLEKSPQFSYKQQESRDLADIQSMLNVTSTPSSFIRNFENYVNAPSSEHGYGKDEEEAQDAFTSEFRKMKLRGEFPCKLCSAVFPNLRALKGHNRIHLSAAGAGPYRCNMCPYSIHDKAALIRHMRTHNGDRPYECAVCNYAFTTKANCERHLRNRHAKTTREEVKRAIIYHPSEDSSCEDPIKKMHLFSSPEFDQDEEQCAPKDRSTPLSHLKEMLQSEKPLKIQVKSLEKLIDKSYKNYEEAEKRSGEQEENNDSNRPIDLSMDVLDLSKKAKPNPPSEEKVELEAPSEATPKVDMSTIEKNNQILLAQQQFINEALPKMDPSQYFQLSQLYRNFMFSPLHPFFLPNGLMPNNINDLNKFTPNLLMNSMFNGDHRAPQTSPAAASSQCQPSPHSQQVPVSTIENSLLKGSPASAQLLQKSMQPTSPQINIPRHPHLGQPPPQQPTLVPPSQNTGPVKMVIKNGVLMPKQKQRRYRTERPFACEHCSARFTLRSNMERHIKQQHPQYWAQRQRSGHHIMRRSTNSAAMPQISSSTLPPSVPSIPTTHFNAISDQVKYAILAQQLKTRKDTDILQQTLSQGSSSSHGNSGVFNSTNNQTSNAHSNVEDDDPKLVIDEDEEVENDDIPEDETKPEDLSKNTDATPSENSAAKKVADSILEQAIRASANSIKNSTPPKCSEERETKDFGLKIASNMIARAESVGKYLKEVASSPFKDESSDLASVSKLVDNATNSMSFNNYFRPSDLPNQMEQSDEEGLVASGSASESNNSGTEETHSTIGQDQKKKSAYSLAPNRVSCPYCQRMFPWSSSLRRHILTHTGQKPFKCSHCPLLFTTKSNCDRHLLRKHGNVESAVSLYVPIEDIPDPVPTPKAVEEPENKSANSLNVNLNVPNIKPEPMISSSDLPFKCHLCDGSFSERIHCLDHIKIHHAQEFALLLAKGAIDADADYNHVQMADDDERNDGRGKYPDYANRKVICAFCVRRFWSTEDLRRHMRTHSGERPFQCDICLRKFTLKHSMLRHMKKHSGSHHNSQSNATNSGSDMSDDEQPSSMILSNYRTHKIQEILSKAEALRKSHLTGEQKDLIAMHPFVKSEGNGEDNNSDLIGNLLGISDQGILNKLLSSADEAAKLLGVEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01184049;
90% Identity: iTF_01184049;
80% Identity: -