Basic Information

Insect: Machimus atricapillus
Gene Symbol: Hivep1
Assembly: GCA_933228755.1
Location: CAKOFS010000003.1:609142-619591[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00034 0.062 14.8 2.1 1 23 263 285 263 285 0.97

2 8 0.0042 0.77 11.3 4.8 1 21 291 311 291 315 0.89

3 8 0.0025 0.46 12.0 0.1 1 20 710 729 710 731 0.94

4 8 5.8e-06 0.0011 20.3 1.7 1 23 1457 1479 1457 1479 0.99

5 8 1.8e-05 0.0033 18.7 5.3 1 23 1485 1509 1485 1509 0.92

6 8 0.0012 0.23 13.0 2.2 2 23 2014 2035 2014 2035 0.97

7 8 0.0031 0.57 11.7 0.8 1 23 2041 2065 2041 2065 0.91

8 8 0.0031 0.57 11.7 2.5 1 23 2086 2110 2086 2110 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00034	0.062	14.8	2.1	1	23	263	285	263	285	0.97
2	8	0.0042	0.77	11.3	4.8	1	21	291	311	291	315	0.89
3	8	0.0025	0.46	12.0	0.1	1	20	710	729	710	731	0.94
4	8	5.8e-06	0.0011	20.3	1.7	1	23	1457	1479	1457	1479	0.99
5	8	1.8e-05	0.0033	18.7	5.3	1	23	1485	1509	1485	1509	0.92
6	8	0.0012	0.23	13.0	2.2	2	23	2014	2035	2014	2035	0.97
7	8	0.0031	0.57	11.7	0.8	1	23	2041	2065	2041	2065	0.91
8	8	0.0031	0.57	11.7	2.5	1	23	2086	2110	2086	2110	0.92

Sequence Information

Coding Sequence: ATGTTCGGTAGTCCAGATGATCAGAGCACTCCTCGCGATATGGAGGAATCTAAGCTGATATCGAAAAAGCTACACATAAAGGGTAACGAATATCAGAAAGATTCCAAAATTAGCGCAGATCGACCATCCCACCGAAAAGAGAGTTCAGATCGAAGGGCGGATGACGATGAGCTTGTACATAGAACACCAAGTGATAGCACGATTTCAACCGATCTTATCAATAGTAATAATAACAATAGTAAAACATTGAACAGTTCATCGAATGACCTTAAGTACCTGCATAAAAAATTCAAACGAATCGCCAGTGCCACATTAGACGAGGTTCAGAGGCAGCCTCCAGAAGTCGTTAAGAATCTCCAGACAACTCTGACAAATAGTCAGGAGAACTCGGTTAAATCCATCAAGGGTCAGGGTCCGCATGCAGCTTTCAATGGGCATGTGGACTATGTAAATATTAAGAGGGAATTTTTAGCTTCCGAATTAAATGGCGAGGGACCCGAAGGGGTGGGCTTATCGAACAACTTTAAAGTCAAGTTCTCACCATGTAACGATGATAGTTCGCACAGTAATTTTTCAATAAAAGTTGAGAGAACTTCATCGCCTGTGACGAGCCAGAATAACAATGTCTTGGGGCGGTTACCTTTAATCGTCAGCAATTTCAGTGGCTCGACAGTGTCTACGGTGTCTGTGACGAATGTCGGAAGTAGTCTGAGGGTACACCAGCCCCAAGTAGCATCACAGCGACCGCAACAACGAGAAGTAGTTGACCAAAGTTTCTCTGGGCGGCATGTGTGTCCCTACTGTAACTTGAACTGCACGAAACCGTCGGTTCTACAGAAACATATCCGTGCTCATACCAATGAACGACCATATCCTTGTGATACTTGCGGTTTTGCATTTAAGACGAAAAGTAATTACTATAAGCACTGCAGGTCTAGATCTCACGCTCTTCGAACAAAAGGAGGGGAAGCACCACCAGACGATGATGCTTCTCTTGGATCGGATCAGGATCAGGATCCAGACTTAAGTAACAGTAGCTCCGATGTGATAAGCAGAACAGCTTCTCCAATGGATGAGAGGACCTCGTCACCAGCTGTTCAGCAACAAGCTGCCCAATCAATTCAGAAATATTCAAATGAGAAGCCATACAAGCCGAAATTCCATAATGCCGCTTTGTACGCCAAAGaggaaatttcgcaaatacagaagcagcaacagcaacaacagcaacagcagcagcaacaacaacaacatcaacatcagcaacagcaccaacaacacaataacctcaaccatcaaagtcattcgacagATTATTACCCCGCAGTCCCACAACCCCATCAGAGCCTCGATTCCCTTATGCAGCAACAGTCACAGGGACAGCCTTCCAGGAGTCGGGGGGACCAGGCGCCAGGACTCCCAACCAATACGCAGGGCTTTCAACATGTGCCGCCGCCGTCTGGTTACGTCGAATCAACACCGCTATCAAGTCGGGAGTCAACAAGTGCGTCCTTCAGCGGAATCGTTGTGGCTGGCGGAGGACATCAGTTGAACCGTGAATTTCTACAAGAACACATTTCGAAAATAATTTCGCAAAATGAGGCTATCGTAGAAAACAAAGAGTTGCTGCTTCAAAAGAAATATCCAAAGTTATCGGGAAAGTCGAAAAATTCGACAATAATCTTATCGAACGAAAGCTCCAATACAAAATTAGCATTTGCTTTGGCTAATAAGCAACAGCAACAACACCTTCAGCAGCAAGGTCGCGATGATGTGACCATGTGCAAGTCTACTGCCATTAGTAACTCAATGGCCAACAATACCGCGGTCTTGCTGGCTTCTAGAGTAAATCAACATAATATGAGCCAAGCTAGTCAATCCCAGGAAGCTCCGGTGACATTCCAACCGTTAAATTTATCGAAAATTGCTGAGCAAATTGATATGAGCAGAAAACGACTCCCGGTGGAAAGTCCTTCTTCGGTGGTCTCTGAAGGGAATTTACCAGCGACATCGGGGATCAAAAGCGGACCAAGCAGACTTGTAAATCAAGAGCGATCTATCATAAAACACTTGTTGCTGAATGCTAGGGGCTTGGGAGTACCAAATGGCGAAGGAGAGGATGCGGTGTATATTTGTCCGCTTTGTAAAATGGAGTTTAGATCGGCTGAAGATTTAAAGTTGCACACTAGCAACTATTGCCAAGGCGGACCATCGAGTGCACCTATTAGCCCTGTGGCATCGCCATCGTATAAATATTTCCGCTCGAATTCAATCAACGTCAGCCTACCGGAGTTCAATAATCCTAATTCGCTGGCTAAGCTGGCCCGGTCATCTTTATTACATCTATCGAAAAATCCTCTGTCCCTTGCAAAACTGGCGTGGTCTCAGTTGAAAACGAAACCCAGTAATCTTGTATTGAGTAAGCTTAGTGTTAATACAAATACCACGGCCGCTAGCTCGAGTAATGCAAGTGAAAGCACCTGTTCTACTCATACAAAAAATATAGACGCACCGTTGCCATCACCGGGCCCGTTGCTAGGGAAAACGCCTCTTGTTGAGTCGTACAACAATTCGGAGCGAAAATCTGAAGACGTTGTGATAACAAAGGTGCATGAAGAAAATAGAAACTTTATAAAATTTTCATCAAAGCGGCTGAGGCTGAATCATTATCCACAACAAGCTTTTCAAGGAATGCTGAGCGATGCAAATGCAGCGTTGGGTAGTAACAGCATTTCGAGCTACAATAACACGAACTTACCTTTTGAGGTATCGCCGATGAAGTATGCAATGTGCGGCGGAGAGGTCCAAATGTTGGATAAAAAGGAGGATAGAATGAAGAGATACCTCTCCTCAGGAGGGTGCGTAATTCCAATCTCAGAGTGTCCTGATATAGAAGTCAGTCCGAAAATGATTCGAACACCTCTCTTATCGGGCGGTAGTTTTACAGAAGTCTCACCGAAATCGTCAATTAAAGATACTCCTCCAACTCCATCCAGTACCCCAAAAATGATGATACCCATAGCGCCGCTAACGCCCAGTCTTCCTGCGCCGAACTTACTCAGTGCCAGCCTGCCATTGGCAACACATTTTCAATTTCCTCCAATTAATTCAATTACTGCATTTAATCCATTGACCCTTCCTCCGGTGTCTATAGTTCCATCGACGGTTATGCACGGAGATAAACTTATACCGTTCGTACCTGGAATTCCTGGTCCAAATTCTCTGGCACCACCAACTTTAGTCCATCCTCCGCAAATTGCCAGCGATATTTCACTGTGTCGTAATCTTAGTCCGAGTAGGAAAAAGGAAACGAATATTTTAAATTCAATTAATGTCCAACCGGACGGAGTGCTCCATATGACTCCAAGGATGGTTAAACCGATTATTCGAATTGAAGGCGAACTTCCGTCCCCTGTAGGCGATTCAAGTCGATTTCTTCAAGGAAGCCCAAGGCATTCACAACCAGGAACTGGAGTAGAATCAATAAAAAAATCTTTTAACTTCACTCGAATGGCAGACAATATCAGTCCTAGGAAAGGGATAATTGAGAAGACGACAAAATCTCCTGAAAAGGAACGAGAAATACGTCACTTTAATTTTGAAAATATACCGAAAGTCGATATTATCGCAATTTCGCAACCATCGCAGCTCCAGCCAATGGCTCCATTGCACGTCGAGGTTTCAAGCATCATAACGAGCCAAAATATTCAAAAACAGCCGTCGGAATACGAACTATCTGAAATGAAGAATAAAGCCAAGTCGAAGTTCCTCAGGCCAACGAGTCTTCCTCTGAAGCCCGGCACGTTCACTCCGAAGCGGCATCACGGCATAACGCCTACAGCCAACACACTGCCCTTAATTTCTCCAGAAACTCCGCGTCCCTCGAAGGCCTGCATTCAGCTCTATCTCAATGGGCACGCTTACACTTACCTGGGGCTCAAGTGCAGCACAAAAATGTTCTACTGCACTGTGAACTGTCCGCAACCGTCGTACGTTGCTAATCTCCACAAACTCTCAATGTACAGCGTTTGGCAGGTCTGTGCCGAAAACAATCCTCATCCTCTTGGGCTCAAGCCGAAGGAGGTTATGTCCCTCTACGACACGCGCCAACGAAATTCAGCTTATACCACAACGACGATTAGTGCACCCTGCACCGTGGTCCACTCACAGCCTCCGGTGATGACGCCCTTCGAAAGCAGTGCGGCCACATCCGGACAGTTTTATCATCACCAGGTGAAGTCCATTCAACCTCCAGTTGATCCTGGCTTGAAATCAGATGGGAGCTCGAAGAGTAGTGGGAACGTTTTAGTCGGAGGATATGAGAGCCACGAGGACTACACTTATATTCGGGGAAGGGGTCGAGGTCGGTATGTCTGCTTGGAATGCGGCATCCGATGCAAGAAGCCATCTATGCTTAAGAAGCACATCAGAACTCATACCGATGTGCGGCCATATACTTGCCAACATTGTTCCTTTAGCTTTAAGACGAAAGGTAACTTAACAAAACACATGCAATCGAAAACACACTATAAAAAATGTTTAGAGCTTGGTATTAATCCTGGTCCAATGCCCGCCGAAGGCGAATTTATGGACACTGATGGCGACACAGATCAGCAGTCAGTTATTTCTGCCGGGGGTCGCACATCGTCTATTCCTGGTGAATCTGATTCCGATGATTACAGCGATATTGGCGACAACGAAACCGAAAGCAGTGATACAGATGAATCAAAATCAAGATTACCCGAGCATGAAGCGGCCCGGTGCCTTCTATCGCTTTCTATGACTCCTCCAGCAAACAGCGTTTCGCAGCACATGCACCAGAGTCGACCGCAGTACGGATTCAAGCAAATGGAGCCTATGCAAGTGAGTAGCGTCAATGCAGGCCGATCTTCAGAGGAGGTGCAGCACGCTGCTGTGCAACCTTACTCCTCAAGACGTGTAATTTCATTTACGTCTCCAAAACCACCGTTCGACTATCAAAAACAGGAGCAGTACTACTCAAATCCGAGTATAATTCCAAAGGGCAGGGACGAAAAGTTTGATGAGTCAAGCATGAAGCCGATCGATTTGACCAAACCTAGGCACGTCGTAGATAAGCCCAAAATATTTGAAGTTATTGGCGATTTAACCAATGAGTCAGGATTGTTAAAGTCTTTAGTGTCGATTACGGATAAAATTAGAAGCTCAACAGAGCCGGCGATTCAGGTTCAAAAAATGGATGAGAGTGTGCTACTGCAGGCGTATCTGACTGAGCAGGCCTTGCAATATACAAAGATTAAGCAGAGCCAAATGAATAAACATTTTCCAGAGGTTATGTCGTGTTCGAGTACATCAACAGTGACCTTGACCGTTTCGCCTTCTAGAGGTTCGGTTTATGAAAGAGTTCCAGAAAATGTACTTAGTGGAACTCCATATTCTTCTAGAACTCCAGAGCTATCATCGGTAGTTTTTTCTACTATAACTACGCCATGCACGTCAGTTATTAGACCATCTTCTGTAGTAGATGATCAGATGGATAGGTTGGATAGGTCGATAGAAAAAGATTGTGAGAAAGGGATCAGCACAGAAGTGATAGTTCCCGCTCCACTAGATCATCGGCTGGAGTCTAGCCGAAGCCCGTCTTTGATTCAGGGTGATTCTAAAATAGAAAGCGAGCACAGATCTCCAGCACATTTTAATTCTTCTCCGATTTGCTCTGGTGTATCGGTTCAAGAGCCTAGCAAAGATGTGACTCAGAGCCCTAGACCGAGGTCACTTCCACCGGGGACAGGTGGGGCAAAAAGCGTTGCGTCTGAGTACCTCAAAATGACTTCAGCAGAACTACTGAAATCGAAAAGTAGTCGTACTGAAGAAAGTGAGGAGAGCAGCTCGGATCAAGAGATTAATGTGACCGAGACTGGATCATCAATTAAACCGCCTGCAGATTTTGCAGGGGTCTTAGCGCGCACGGTTATCGTGGGAGAGGATGGATTTAAGAATAGTTCAAATGAAGTACAGCCGATGTTTCCGCGGGTCCCTCTTTCAGACGATGGTCGACCGGTCTGTACGATATGTTCAAAAACGTTTCAGAAGCAGCATCAAATGGTCCTTCACATGAACATCCATTACATGGAAAGAAAGTTCAAGTGTGAGCCATGCGCGGTCAGCTTTCGGACACAGGGTCACTTGCAAAAGCATGAACGATCAGAAGCTCACAAGAACAAAGTGATGATGACCTCCACTTTCGGGGTGCCTACCACTTCTAATCCTCGTCCTTTCGAGTGTTCAGATTGTAAGGTTGCTTTTCGTATTCATGGCCATTTAGCGAAGCATCTCCGTTCAAAAACTCATGTACAGAAGCTCGAATGCCTGCAGAAGTTGCCGTTTGGAACGTATGCTGAAATTGAACGTGCTGGAATCAGCCTTACTGAAATCGACACTACTGACTGTGATAACTCACTTGCTAGTCTCAAAGCTCTTGCTCAGAAGCTGATTGAAAAGGATCCCACAAAGTTGAACTCGTACAGCACCTCACCCTGCATGGAGACGAACTCAGCCACAGGATCGCATGAAAGCGGCAGCGAAGATAGTCCTGATCGGCAGGCAGAATTGAACGATATGCGGGACCTTCCGGACGTCCCACTGATGGCTGTCTCAGTACCACCACCCGCAGAAGGATCAGGACTCAAACGGAAATTCGACTCCGTAAACAATTGCAGCAACGACTCGCTCGCAGTTGGACCACAAGAAACGCTGGAGAAACGGCTACGAACTACTAGTGAAACCTAG
Protein Sequence: MFGSPDDQSTPRDMEESKLISKKLHIKGNEYQKDSKISADRPSHRKESSDRRADDDELVHRTPSDSTISTDLINSNNNNSKTLNSSSNDLKYLHKKFKRIASATLDEVQRQPPEVVKNLQTTLTNSQENSVKSIKGQGPHAAFNGHVDYVNIKREFLASELNGEGPEGVGLSNNFKVKFSPCNDDSSHSNFSIKVERTSSPVTSQNNNVLGRLPLIVSNFSGSTVSTVSVTNVGSSLRVHQPQVASQRPQQREVVDQSFSGRHVCPYCNLNCTKPSVLQKHIRAHTNERPYPCDTCGFAFKTKSNYYKHCRSRSHALRTKGGEAPPDDDASLGSDQDQDPDLSNSSSDVISRTASPMDERTSSPAVQQQAAQSIQKYSNEKPYKPKFHNAALYAKEEISQIQKQQQQQQQQQQQQQQHQHQQQHQQHNNLNHQSHSTDYYPAVPQPHQSLDSLMQQQSQGQPSRSRGDQAPGLPTNTQGFQHVPPPSGYVESTPLSSRESTSASFSGIVVAGGGHQLNREFLQEHISKIISQNEAIVENKELLLQKKYPKLSGKSKNSTIILSNESSNTKLAFALANKQQQQHLQQQGRDDVTMCKSTAISNSMANNTAVLLASRVNQHNMSQASQSQEAPVTFQPLNLSKIAEQIDMSRKRLPVESPSSVVSEGNLPATSGIKSGPSRLVNQERSIIKHLLLNARGLGVPNGEGEDAVYICPLCKMEFRSAEDLKLHTSNYCQGGPSSAPISPVASPSYKYFRSNSINVSLPEFNNPNSLAKLARSSLLHLSKNPLSLAKLAWSQLKTKPSNLVLSKLSVNTNTTAASSSNASESTCSTHTKNIDAPLPSPGPLLGKTPLVESYNNSERKSEDVVITKVHEENRNFIKFSSKRLRLNHYPQQAFQGMLSDANAALGSNSISSYNNTNLPFEVSPMKYAMCGGEVQMLDKKEDRMKRYLSSGGCVIPISECPDIEVSPKMIRTPLLSGGSFTEVSPKSSIKDTPPTPSSTPKMMIPIAPLTPSLPAPNLLSASLPLATHFQFPPINSITAFNPLTLPPVSIVPSTVMHGDKLIPFVPGIPGPNSLAPPTLVHPPQIASDISLCRNLSPSRKKETNILNSINVQPDGVLHMTPRMVKPIIRIEGELPSPVGDSSRFLQGSPRHSQPGTGVESIKKSFNFTRMADNISPRKGIIEKTTKSPEKEREIRHFNFENIPKVDIIAISQPSQLQPMAPLHVEVSSIITSQNIQKQPSEYELSEMKNKAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKACIQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVANLHKLSMYSVWQVCAENNPHPLGLKPKEVMSLYDTRQRNSAYTTTTISAPCTVVHSQPPVMTPFESSAATSGQFYHHQVKSIQPPVDPGLKSDGSSKSSGNVLVGGYESHEDYTYIRGRGRGRYVCLECGIRCKKPSMLKKHIRTHTDVRPYTCQHCSFSFKTKGNLTKHMQSKTHYKKCLELGINPGPMPAEGEFMDTDGDTDQQSVISAGGRTSSIPGESDSDDYSDIGDNETESSDTDESKSRLPEHEAARCLLSLSMTPPANSVSQHMHQSRPQYGFKQMEPMQVSSVNAGRSSEEVQHAAVQPYSSRRVISFTSPKPPFDYQKQEQYYSNPSIIPKGRDEKFDESSMKPIDLTKPRHVVDKPKIFEVIGDLTNESGLLKSLVSITDKIRSSTEPAIQVQKMDESVLLQAYLTEQALQYTKIKQSQMNKHFPEVMSCSSTSTVTLTVSPSRGSVYERVPENVLSGTPYSSRTPELSSVVFSTITTPCTSVIRPSSVVDDQMDRLDRSIEKDCEKGISTEVIVPAPLDHRLESSRSPSLIQGDSKIESEHRSPAHFNSSPICSGVSVQEPSKDVTQSPRPRSLPPGTGGAKSVASEYLKMTSAELLKSKSSRTEESEESSSDQEINVTETGSSIKPPADFAGVLARTVIVGEDGFKNSSNEVQPMFPRVPLSDDGRPVCTICSKTFQKQHQMVLHMNIHYMERKFKCEPCAVSFRTQGHLQKHERSEAHKNKVMMTSTFGVPTTSNPRPFECSDCKVAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTTDCDNSLASLKALAQKLIEKDPTKLNSYSTSPCMETNSATGSHESGSEDSPDRQAELNDMRDLPDVPLMAVSVPPPAEGSGLKRKFDSVNNCSNDSLAVGPQETLEKRLRTTSET

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01461432; iTF_00718054; iTF_00937572; iTF_01184080; iTF_01049928;
90% Identity: iTF_00937572;
80% Identity: -