Basic Information

Insect: Machimus atricapillus
Gene Symbol: -
Assembly: GCA_933228755.1
Location: CAKOFS010000193.1:186622-188836[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 8.4e-06 0.0015 19.8 2.8 2 23 246 267 245 267 0.92

2 12 3.4e-07 6.3e-05 24.2 0.3 1 23 273 295 273 295 0.98

3 12 1.5e-05 0.0028 19.0 1.8 1 23 301 323 301 323 0.98

4 12 5.2e-06 0.00096 20.5 1.1 1 23 329 352 329 352 0.96

5 12 0.00034 0.063 14.7 2.4 1 23 360 382 360 382 0.97

6 12 1.7e-05 0.0032 18.8 4.6 1 23 390 412 390 412 0.98

7 12 2.9e-06 0.00054 21.2 2.6 1 23 418 440 418 440 0.99

8 12 8.8e-05 0.016 16.6 4.3 1 23 446 468 446 468 0.99

9 12 2.6e-05 0.0049 18.2 1.7 1 23 476 498 476 498 0.98

10 12 0.00035 0.065 14.7 2.0 1 23 506 529 506 529 0.95

11 12 0.00078 0.14 13.6 0.0 2 23 538 560 538 560 0.93

12 12 0.0037 0.67 11.5 1.6 2 23 566 587 565 587 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	8.4e-06	0.0015	19.8	2.8	2	23	246	267	245	267	0.92
2	12	3.4e-07	6.3e-05	24.2	0.3	1	23	273	295	273	295	0.98
3	12	1.5e-05	0.0028	19.0	1.8	1	23	301	323	301	323	0.98
4	12	5.2e-06	0.00096	20.5	1.1	1	23	329	352	329	352	0.96
5	12	0.00034	0.063	14.7	2.4	1	23	360	382	360	382	0.97
6	12	1.7e-05	0.0032	18.8	4.6	1	23	390	412	390	412	0.98
7	12	2.9e-06	0.00054	21.2	2.6	1	23	418	440	418	440	0.99
8	12	8.8e-05	0.016	16.6	4.3	1	23	446	468	446	468	0.99
9	12	2.6e-05	0.0049	18.2	1.7	1	23	476	498	476	498	0.98
10	12	0.00035	0.065	14.7	2.0	1	23	506	529	506	529	0.95
11	12	0.00078	0.14	13.6	0.0	2	23	538	560	538	560	0.93
12	12	0.0037	0.67	11.5	1.6	2	23	566	587	565	587	0.96

Sequence Information

Coding Sequence: ATGAACCTGAAAGTGGATATAAACGTCTGCCGGGTGTGCCTCAAGTCGGAGGGCGGCGTTTCGCTCTACGAGGACCTGGCGCTGATCGAAAAATTCCAAAACATCACCCAGCTAAAGGTAAAAGAAAACGATGGAATGCCAGCGATTTTGTGCGGGATGTGTGCGGCACGGCTGAATGTGGCCCACGAATTCCGGAAGCAGGCAATCATCTCGGAAAGACACTTGCGAGCCTTCATCAGTAAAGTGAACACCCAATTCAAGGAGGTGGCCAACTCCACGGTGACCACCTCGAAGCGTTCCCTCGAATTGAACGATGACGAAATGCGGGTACTCGTCGAGGCCGGGTACAAGCCCCCAGAGTCTGAGATATTCGAGATGCCCCTGATCGACTACCAGGGAAAAGTGGAGGATATTGAAAACTTGGAGAATGCCGAGGAGGAGGCCCAGACTGAGGACGATATGTCCCAGCACATCGAAGAGGACTTTGGGGGCTTCATCCAGGAAGACGATGACGGCGAGGGCAACCCCTTCTGTGATGAGGGTGATGACGAGGAAATGCACCTGGAGGAAGAGGAGAACATTTCAACGTCCGAAATTATCGGGGACAATGTGTCCAATCACGAGGACGGCCTGACCGGCATCAAGATAGTGCAAACTGAAATTGCCGAGAGGTTTATCATTTCGGAGGTGAAAAAGGACCCTTTGGAAAAGCCGAGGAACgagaatcggtctcacatctgcataaagtgcgacaaggacttcagcacaaagacgaacctcatgaggcacatgttgacccatgatggggtcaagccgtttcagtgcaacatctgcgggaacgggtttacccaaaacgggtcccttaagcagcacatgctcatccacaccggggagcggccccacaaatgcgagatctgcgggaggggattcacccaggcaaagtcgctagtcttccacatgaggaggcatactggcgaaaagccgtttgcgtgcaataagtgtggGCTAACTTTTCGGCAAAAGGATGGGAtgaagCGTCACGTTCAAATGAAACATTCCGGAATGCAATCTGAAGTCCACATTTGCTCAATATGTAATAGAGTGCTACAATCAAAATATTCTTTATCTCTAcatatgaaaaaacatatcggacaccaagatactagtcacaagtgtgaaatctgcgaaaggacattctcatcaaaatcatcattagatattcatcatcgtcagcacacaggtgagaagccatttaagtgtgaaacatgcggaaaagaattctttcgcaaaagttctcttgtaacccactcgaagactcatctcgaggacaagccttataaatgtaacacatgtgaaaaaggttttGTGCAAAAGCACCAAGTCCTCGCTCACATGCACAGGCACAAGAGCCACCCACCAAAAACATTTCAGTGTGGTAAATGTTATAAAAGTTTTGCCATAAAACGAAATCTGCTCCAGCACCTCCGAAACCATAATCGAAATTCAATGACCATCTTCAAGTGCGAGGAGTGCAGCATAGCTTTTAACACAAAAAGAGGTCTCAAGTTGCACAGGCACAACGAACACAAGGAGACCGTCTCTGACCTGAATGAATGTGATATCTGTAATATTCCCTTTGTCTCCGTTAACGATCTTAATCAGCACATGATTGCAGTCCATGATAGAATCGACGATAAATGTGAGCTATGTATGCAACATTTCACTTCGAAAAAACTCTTAGAGGATCACATGCTGGAGCATGAACTTTTGACTATCAGTTGA
Protein Sequence: MNLKVDINVCRVCLKSEGGVSLYEDLALIEKFQNITQLKVKENDGMPAILCGMCAARLNVAHEFRKQAIISERHLRAFISKVNTQFKEVANSTVTTSKRSLELNDDEMRVLVEAGYKPPESEIFEMPLIDYQGKVEDIENLENAEEEAQTEDDMSQHIEEDFGGFIQEDDDGEGNPFCDEGDDEEMHLEEEENISTSEIIGDNVSNHEDGLTGIKIVQTEIAERFIISEVKKDPLEKPRNENRSHICIKCDKDFSTKTNLMRHMLTHDGVKPFQCNICGNGFTQNGSLKQHMLIHTGERPHKCEICGRGFTQAKSLVFHMRRHTGEKPFACNKCGLTFRQKDGMKRHVQMKHSGMQSEVHICSICNRVLQSKYSLSLHMKKHIGHQDTSHKCEICERTFSSKSSLDIHHRQHTGEKPFKCETCGKEFFRKSSLVTHSKTHLEDKPYKCNTCEKGFVQKHQVLAHMHRHKSHPPKTFQCGKCYKSFAIKRNLLQHLRNHNRNSMTIFKCEECSIAFNTKRGLKLHRHNEHKETVSDLNECDICNIPFVSVNDLNQHMIAVHDRIDDKCELCMQHFTSKKLLEDHMLEHELLTIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01183995;
90% Identity: iTF_00717972;
80% Identity: -