Basic Information

Insect: Machimus atricapillus
Gene Symbol: IBTK
Assembly: GCA_933228755.1
Location: CAKOFS010000057.1:68839-74427[-]

Transcription Factor Domain

TF Family: BTB
Domain: zf-C2H2|ZBTB
PFAM: PF00651
TF Group: Zinc-Coordinating Group
Description: The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 3 7.3e-09 3.4e-06 28.2 0.5 1 87 541 622 541 630 0.87

2 3 9.3e-16 4.3e-13 50.4 0.1 9 104 688 786 680 792 0.85

3 3 1.4 6.5e+02 1.5 0.1 74 109 790 823 767 824 0.80

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	3	7.3e-09	3.4e-06	28.2	0.5	1	87	541	622	541	630	0.87
2	3	9.3e-16	4.3e-13	50.4	0.1	9	104	688	786	680	792	0.85
3	3	1.4	6.5e+02	1.5	0.1	74	109	790	823	767	824	0.80

Sequence Information

Coding Sequence: ATGTTTACAATCAGCAATTACGATTACGAGTGCACCAAGAGGTGCACCTCCAAGACGCACGGGACCGCAATCACCGCAGCCCTAACGAAGCGAGCAGTTAGCGATGGCCAGCTTGCGGCTTACATTGCCAAAACTTGCCGAAATTTTGCAGAGATTACGGACAATTTGGGCCGAACGGCACTGCATTTGGCTTCCTCCGTGGAAAGATATGCCATAGTGGAATGGCTTTTAAATCATGGAGCATTGATCAACCTGAAGGACGCTGAATCTGGAAGTAGTCCACTCCATCGAGCGATATTCTACGGCTGCATAGACTGCGCTGTCCTTTTGATACGGTATGGAGCCAACTTGGAAATGCCTGATTCAGATGCCCGACAACCGTTGCAACATGTCTGCAAATTGAATGATTTACCTCTTCGTGGGGCAATACCTGAAAACAACGAATTATTGGTTTGGGGCAGCAACAAAAATTATAATCTCGGAGAAGGGAACGATCAGGCAAATAATACGCCTCATTTCATAGATATGTTTCGTAAGAATAACATTTGCATCGTTTCTGTAGCCGTGGGTGCATATCACAGTTTATTTCTGGATATCAAAGGAATTGTATATTCAGTTGGACACGGTAAAGGCGGACGGCTTGGAATTGGATCTGAAAATAGTTTAGCATCTCCAAAGAGGGTAAAAATGTCTGGTAAAGGAAGCGACGAAAGAGTGATTTCTATTAGCTGCTCCAAGAATCATTCATTGTTATTGACTAGCAGCGGGAGAGTGTGCGCAACTGGGCTAAACACTGACCTGCAACTGGGATTTAAGCCTGCTCCTGAATTACTCACATCGTTCAAGGAAATTCCTGCATTTAGTCAGTATGGAGTTACTGATATTGTTTCTGTTATTGCTCAGGACCATCATTCCGTCGCTTACAGCTATAAGGAGTTGTTTGTATGGGGTGCTAATCATGGCCAATTTGGCGGTATTACCTCAACCCATATTCTTCTGCCAAAACAAATTAATCTACCTGAAAAGACAATTGTTCTTGTGGACTCCAACAACGTTGCTATTGCGTGCTGTACATCATCTAAGCAAGTTTATATTCTTTACAATAATAAAATCAAGTCTGTAAGGTCACCAACTTTGGAGAACATTAAATCGATATGCTTATCAGGCGGTGAAGATCAGAAAAAGGAAAAATCTGGAGAACTTAAACTGCTACTGCTTACAAACTGTAATAACATTTATATTTGGTACGATGAAATGCAAAAGTTTCTAAGGTGCACAATTGCTTATTACCGAGTCTTAGATATCGAGAAAATTATTTTTAAATCAAATAAAGTCATGATTTTGTCACAAGGCGATGTATACAGTGGGAACGCTGTTAAAGTGCCAGTCCAATCCATCGGAAGTGATCATCACAGTACCTGGCATTCATGTCCGTTTAAGCAGGATTTGTGCATTGATCAGAAAATACGGTTTGAAGTCAAACGAGTTACAACTGTTGACAGGGTTGTGGATGTGGCTTGTGATGATGATTTTGAATCATTTGCAATACTACAGGAAAGCTCTCGGAAGTATTATGTCCTTCCGCAACTAATGGCTGAGGAATATAATTTTAAAAATCTTTTAAATGAGGCCAGTGAATTTGATTCCATTCATGACATAGTTTTTCATGTGGGTGCTGAAATCTTTTACGCCCATAAACTAATCGTTTTCTCAAGGTCATCCGGCTTAAAGGCAATTGTTGAGAAATATAAGGATAAAGATGTCTTCTTAAATTTTAGCGACTTGACAGGAAAGATGTTTGAATTCATCTTAAAACATATTTACGCAAACTATTTATTGACTGAAGAAGATTTTGACGAAATTTTTCAATCGATGGGACCACATTATGAAGGCAATCGATGCGAAGCATCTGGACTATTTCTTAATTTTGTTAAAAAATTTGAGTTATCAAATTTGGCGAATTACGTCACAAGTTATCAAGACTACTTAAGTAGTGAAGATGTTCGTCCGATAGAGAAACAGAAATACCGCTTCAATCGGTTAAAACCAACATCATTCCCAAAATTGCACGATGTGACCATAACATGTGCTGGCAACCGAGAAATACGGGCACATAAATGCATCCTGGTCACTCGTTTGGAATACTTTAACATGATGTTTACCAACAGTTGGTGTGAGAACAAGGTTATAAATCTTTCTACGATTCCCTTCGAGTACATGGGTCCCATTATCGATTTTCTATATACTGCTGATGTTGACCATTTCAGACGGCAGAACTACTCTGAGACTTTCTTGTACAACATGATTGTTATCTGTGATCAATTCTTCATTAATAGACTGCGCAAAGTTTGTGAGATTTTAGTTCTTGATAAAATCTCCATCAAGAAGTGCGGAGATATGCTCGAGTTTGCTTGCGCGTACAATTGTAGCTTTCTCAAGACAGGCTGTCTAGACTTCATATGCCAGAATTTAGCTAGGGTATTGATGCAGCGCAGTTTGGAAATATGTGAGCCAGAAGTTTTACATAGTATCAATGCATATTATCGCCAAATATTTAAGGATACTTTTGATTTTCGAGCAATAACACCAGACTCAAACGCTGTGGATGATGCGGTGCTTAAATCCTTTGTCGACGACTTTAGCGTTGATTTAGACCATAAAATGTCTGGAGATAGTATCAAGAAAACAAAGAACAAAATTAAGATGAGTAAAACTGCACAAAGCAAAAGGAATTATGAGAAAGAGGCTATTTTTTCTATGAAGGAGTTGTATCTTTCGGAAAATTCTTCTGTTGACACAAACGGCGCAAATAAAAACAAGAAATCTGTTCTAGAAAACGAGATTGAAAACATTAATAAAAAGTATAAGGAAGAGGCTCATACATGGATTACACTACATGACAAAAAGAATGACAAAAAGAAGTCGCCGAGTGTAATAGCTACTAAAGTAAATACCATTTTAAAAGAAGAGAAAAAGCCCGACGGCGAGTTTGTTAGCTTAAATCAAGTGAAAACAGCGAATAAACCTCCAATGAAAAATCAGGTTAATGAATCTCCCGAAAAACCAATTGTGACATCACCCACCGCAACACCTCTTTTTAATTTAGGAGGTTTCACTCTTGTAAAAAATGAAAAAATTTCGCAAAAACAGCGCAAGAGGCTTTCGTTCGAATGTAAAACAGAGAGTAAAAGTGCGCCAAGCACACCTATTTCTATTCCTGAACGTCCGAACGCATGGGGGGGTGTGATAAATAATCAGAGCTGTGATCAAACTTCTTTTGCTGATCTTATAAAATCGCCCAAAACACCTCCAACCAAAGTACAAACTGAGAAAACGAACAGCCCTAGGCCAAGTACAAGTGCTGCAACAACCAGTTTTACACAAATTATACAAGATGAGCGTCGACAAAAGGAGTATGCTGAAAAATTGAGATCAAAGCCTTTGGTATTAACGCAGATTGAAGAAACCGCTATAGCTGAATTGAAAGAATTTTATAACGTTGACAACGTCGATGACGAAGTTATTACAATCGATAGGAAGGCCGTTCCGTTTACAGTGAACTTTGCTGTATGGCAATATAACTGA
Protein Sequence: MFTISNYDYECTKRCTSKTHGTAITAALTKRAVSDGQLAAYIAKTCRNFAEITDNLGRTALHLASSVERYAIVEWLLNHGALINLKDAESGSSPLHRAIFYGCIDCAVLLIRYGANLEMPDSDARQPLQHVCKLNDLPLRGAIPENNELLVWGSNKNYNLGEGNDQANNTPHFIDMFRKNNICIVSVAVGAYHSLFLDIKGIVYSVGHGKGGRLGIGSENSLASPKRVKMSGKGSDERVISISCSKNHSLLLTSSGRVCATGLNTDLQLGFKPAPELLTSFKEIPAFSQYGVTDIVSVIAQDHHSVAYSYKELFVWGANHGQFGGITSTHILLPKQINLPEKTIVLVDSNNVAIACCTSSKQVYILYNNKIKSVRSPTLENIKSICLSGGEDQKKEKSGELKLLLLTNCNNIYIWYDEMQKFLRCTIAYYRVLDIEKIIFKSNKVMILSQGDVYSGNAVKVPVQSIGSDHHSTWHSCPFKQDLCIDQKIRFEVKRVTTVDRVVDVACDDDFESFAILQESSRKYYVLPQLMAEEYNFKNLLNEASEFDSIHDIVFHVGAEIFYAHKLIVFSRSSGLKAIVEKYKDKDVFLNFSDLTGKMFEFILKHIYANYLLTEEDFDEIFQSMGPHYEGNRCEASGLFLNFVKKFELSNLANYVTSYQDYLSSEDVRPIEKQKYRFNRLKPTSFPKLHDVTITCAGNREIRAHKCILVTRLEYFNMMFTNSWCENKVINLSTIPFEYMGPIIDFLYTADVDHFRRQNYSETFLYNMIVICDQFFINRLRKVCEILVLDKISIKKCGDMLEFACAYNCSFLKTGCLDFICQNLARVLMQRSLEICEPEVLHSINAYYRQIFKDTFDFRAITPDSNAVDDAVLKSFVDDFSVDLDHKMSGDSIKKTKNKIKMSKTAQSKRNYEKEAIFSMKELYLSENSSVDTNGANKNKKSVLENEIENINKKYKEEAHTWITLHDKKNDKKKSPSVIATKVNTILKEEKKPDGEFVSLNQVKTANKPPMKNQVNESPEKPIVTSPTATPLFNLGGFTLVKNEKISQKQRKRLSFECKTESKSAPSTPISIPERPNAWGGVINNQSCDQTSFADLIKSPKTPPTKVQTEKTNSPRPSTSAATTSFTQIIQDERRQKEYAEKLRSKPLVLTQIEETAIAELKEFYNVDNVDDEVITIDRKAVPFTVNFAVWQYN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01461281;
90% Identity: -
80% Identity: -