Basic Information

Insect: Macaria liturata
Gene Symbol: -
Assembly: GCA_964023185.1
Location: OZ026823.1:8703806-8727110[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 4.7e-05 0.0036 18.2 1.3 1 23 419 441 419 441 0.96

2 20 0.00029 0.022 15.7 0.9 1 20 447 466 447 469 0.94

3 20 2.2e-05 0.0017 19.3 5.6 1 23 488 510 488 510 0.98

4 20 2e-05 0.0015 19.4 3.9 1 23 516 538 516 538 0.99

5 20 3.8e-05 0.003 18.5 5.3 1 23 544 566 544 566 0.97

6 20 0.00021 0.016 16.2 7.3 1 21 572 592 572 594 0.95

7 20 1.9e-06 0.00014 22.6 2.7 1 23 600 622 600 622 0.97

8 20 0.00011 0.0081 17.1 6.7 1 23 628 650 628 650 0.97

9 20 0.0001 0.008 17.1 6.5 1 23 656 678 656 678 0.97

10 20 5e-07 3.9e-05 24.4 1.9 1 23 684 706 684 706 0.98

11 20 5.1e-05 0.004 18.1 7.9 1 23 712 734 712 734 0.98

12 20 2.6e-05 0.002 19.0 6.6 1 23 740 762 740 762 0.98

13 20 2.6e-05 0.002 19.0 4.8 1 23 768 790 768 790 0.98

14 20 2.2e-05 0.0017 19.3 5.0 1 23 796 818 796 818 0.96

15 20 1.2e-05 0.00092 20.1 5.0 1 23 824 846 824 846 0.98

16 20 3.2e-06 0.00024 21.9 6.0 1 23 852 874 852 874 0.98

17 20 6.1e-05 0.0047 17.9 7.9 1 23 880 902 880 902 0.97

18 20 1.2e-06 8.9e-05 23.3 5.3 1 23 908 930 908 930 0.98

19 20 0.00015 0.012 16.6 0.3 1 23 937 959 937 959 0.98

20 20 0.026 2 9.6 5.5 1 23 968 990 968 990 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	4.7e-05	0.0036	18.2	1.3	1	23	419	441	419	441	0.96
2	20	0.00029	0.022	15.7	0.9	1	20	447	466	447	469	0.94
3	20	2.2e-05	0.0017	19.3	5.6	1	23	488	510	488	510	0.98
4	20	2e-05	0.0015	19.4	3.9	1	23	516	538	516	538	0.99
5	20	3.8e-05	0.003	18.5	5.3	1	23	544	566	544	566	0.97
6	20	0.00021	0.016	16.2	7.3	1	21	572	592	572	594	0.95
7	20	1.9e-06	0.00014	22.6	2.7	1	23	600	622	600	622	0.97
8	20	0.00011	0.0081	17.1	6.7	1	23	628	650	628	650	0.97
9	20	0.0001	0.008	17.1	6.5	1	23	656	678	656	678	0.97
10	20	5e-07	3.9e-05	24.4	1.9	1	23	684	706	684	706	0.98
11	20	5.1e-05	0.004	18.1	7.9	1	23	712	734	712	734	0.98
12	20	2.6e-05	0.002	19.0	6.6	1	23	740	762	740	762	0.98
13	20	2.6e-05	0.002	19.0	4.8	1	23	768	790	768	790	0.98
14	20	2.2e-05	0.0017	19.3	5.0	1	23	796	818	796	818	0.96
15	20	1.2e-05	0.00092	20.1	5.0	1	23	824	846	824	846	0.98
16	20	3.2e-06	0.00024	21.9	6.0	1	23	852	874	852	874	0.98
17	20	6.1e-05	0.0047	17.9	7.9	1	23	880	902	880	902	0.97
18	20	1.2e-06	8.9e-05	23.3	5.3	1	23	908	930	908	930	0.98
19	20	0.00015	0.012	16.6	0.3	1	23	937	959	937	959	0.98
20	20	0.026	2	9.6	5.5	1	23	968	990	968	990	0.99

Sequence Information

Coding Sequence: ATGAATCCCGAGCACCACAATATTAATCCGGGAGGTGGCCAGCCCCCTGGGAGTTCAGAGTCTCAAGGGCAAAGAGTGCAGGCTGCCCAACAACAGCAACAAGGAACCCTACCAGCTACTACATCTGCCACAGATTTACGAGTGAACACAGCAGCTGTGAATGTCGCTTTGTCCAGTGTTGCTAAGTATTGGGTATTTACAAACTTATTCCCGGGACCGATACCGCAAGTCTCTGTTTATGGATTACCCACTGGAACTAGAATTGAAAACGGAAAACCTGTTCAGgAGCTCGGCCAACATGCCAGCATACTCAATGGAGACCCTAACATCATCCTGGGGCACCATGCAGGCCAGTCACAGGTCACGGTGTCGGCTGGGGGCCAGCAGATACCTGTATCACAGATTATTGCCACACAATCTGGGCAAACTCATGAAGCGCTGGTTGCACACAGCCAACACGGCCAGGAGCTACAACAAGGTGCTGCGGGATCCCAAATCACGGTCACCGGGCAGGCAACTCACCAGCAGGTACCCACTAACCGGGTCGAATTTGTTCAACACCATAACATTGATATGGGCCATCATTCCCAGCAGCATATGTTGCAGCAGCAACTCATGACAGCGAGACCCGACCACTCTAACCAGCAAATCCAGCTGACAGTGAGTGAAGATGGCATCGTGACGGTGGTGGAGCCGAGCAGCAGCAAGATGGTAGACAAGGAGGAACTGCATGAAACCATCAAGCTGCCGTCCGACCATCCGCTGACCATACATCAGTTGCAGCAGATTGTTGGCCAGCAGCTCGGCAGCCAAGTCTTAGAGAACGTGGTACGCATCGAGCAGGCGACGGGCGAGCCAGCCAACATACTCGTCACACACAACGCAGACGGCACCACCTCGATAGAAGCCAGCGCCTCGGATCCACTCGCCATCGTCAAGGATGAGAAGACGCAGACCAAGATGGACACCGCGCAGTTTGCTATACCCGCTGAGATTAAAGATATCAAGGGGCTTGATTTGAAGAGTGTAGGCGCCATGGGCATGGAGGGCGCCGTAGTGAAGATATCGACGGGCGCCGACCACGACATGACCGCCATGTACAAGGTGAACGTGGAGGACCTGTCCCAGCTGCTCGCCTACCACGAGGTGTTCGGGAAACTCAACGCGGACGGACAGGCGCAGAGTAAAGGTGAGATAGAGATCGAGGTGCCGGGCACCAGCACCATGTCGGAGGCAGAGTCGTCCCCCGGACACCACGCCTGCGACATCTGCGGGAAAGCCTTCCAGTTCCGATATCAGCTCATTGTGCACAGACGGTATCACGGTGAAACCAAGCCCTATAGTTGCCAAGTATGCGGACAGTCATTCGCCAATCCGGTAGAACTGTCCCGCCACGGGAAATGCCATCTTGCGGGCGACCCCGTGGAGAGACACGCCAAGCGACTGCCGCAGGACAAGCCATACGCCTGCACCACCTGCCACAAGACATTCTCACGGAAGGAACACCTTGACAACCATGTCAGGAGCCATACGGGAGAAACACCATacagATGTGAATACTGTGCGAAGACCTTCACGCGAAAGGAACATATGGTGAACCACGTACGAAAACACACCGGCGAGACACCACATAGATGTGATATCTGCAAGAAGAGCTTCACGAGGAAAGAACACTTCATGAACCATGTCATGTGGCATACTGGTGAAACGCCTCACCAATGCGAGTTATGTGGCAAGAAGTATACGAGAAAGGAACATTTGTCGAATCATATGAGGTGTCATACGAACGACACGCCGTTTCGCTGCGAACTGTGCGGCAAGTCTTTTACGAGGAAGGAGCATTTCTCCAATCATATATTGTGGCATACGGGAGAAACGCCCCACCGCTGCGACTTCTGTTCAAAGACCTTCACGCGCAAGGAACACCTCCTCAATCACGTCAGACAGCATACGGGCGAGTCTCCGCACAGATGCAACTTCTGTTCAAAGTCGTTCACGAGACGCGAACATCTGGTGAACCATGTGCGGCAACACACTGGAGAAACACCCTTCCAGTGTGGATACTGCCCGAAAGCGTTCACCAGGAAAGATCATCTAGTAAACCACGTCCGCCAGCACACGGGCGAGTCCCCGCACAAGTGCTCTTTCTGCACGAAGTCGTTCACGCGCAAAGAACACCTCACGAACCACGTTCGGCAACATACGGGCGAGTCGCCGCACCGCTGTACTTACTGCGCCAAGTCGTTCACTAGGAAAGAGCATCTTACTAATCATGTTAGACAACACACGGGCGAAACTCCGCACAAGTGCACGTTCTGCCCGCGAGCGTTCACGAGAAAAGAGCACCTCATCAACCACGTGCGGCAACATACTGGCGTCACGCCGCATGCCTGCTCCTACTGCAGCAAGAGCTTCACCAGGAAGGAGCACCTTGTCAACCATGTCAGACAACACACGGGCGAGACACCGTTCAAGTGCTCGTTCTGCTCCAAGTCGTTCTCGCGCAAGGAGCACCTCACGAACCACGTCAACCTGCACACGGGCGAAACGCCGCATAAGTGCCCCTTCTGCACCAAGACCTTCTCAAGAAAAGAGCATCTAACTAACCATGTCAGAATCCACACGGGCGAGTCCCCTCACCGCTGCGACTTTTGCCAGAAAACGTTCACGCGCAAGGAGCATCTCACTAACCACCTGAAGCAGCACACCGGGGACGCGGCGCACACTTGCAAGATCTGCTCCAAGCCCTTCACGAGGAAAGAACATCTTATTACCCATATGAGATCTCACAGCTGCAACGAACAACCGTACAGTTGCGGCGAATGCGGCAAGTCGTTCCCTCTGAAGGGCAACCTGATGTTCCACGAGAGAACGCACCAGAAGGGCGCGGGCGCCCGGCCCTTCCGGTGCGAAGTGTGCTCTAAGGACTTCATGTGCAAAGGCCACCTGATCACGCACCGGCGCACGCACACAGAGTCGGGCGCAGCGCCGTCCACGGAGCCCAGTCCTGCCGAGGACTGCACCGCCAAGTGTGTGAAGGTGGAAGCGGTGGAGTCGCTGGCCATGGACAGCAAGCCTAAAGTAGAGGAGATACGGGCAGCTGAGTCCATCATAGTTGCACATCCCCAGGCTTCACCCACTAATGCTGCGGTAATGCAGATTCAGAATCAGCAATCCCGTCCTATCGCGGTGTCTTCAGCGGGCGGTATAACGACAGCGACATTCACGCACTCGGCGTCCAACCAGCACCACACCGGTGCGATCGCCCACCACCCAGTCAGCGTCACGTACTAG
Protein Sequence: MNPEHHNINPGGGQPPGSSESQGQRVQAAQQQQQGTLPATTSATDLRVNTAAVNVALSSVAKYWVFTNLFPGPIPQVSVYGLPTGTRIENGKPVQELGQHASILNGDPNIILGHHAGQSQVTVSAGGQQIPVSQIIATQSGQTHEALVAHSQHGQELQQGAAGSQITVTGQATHQQVPTNRVEFVQHHNIDMGHHSQQHMLQQQLMTARPDHSNQQIQLTVSEDGIVTVVEPSSSKMVDKEELHETIKLPSDHPLTIHQLQQIVGQQLGSQVLENVVRIEQATGEPANILVTHNADGTTSIEASASDPLAIVKDEKTQTKMDTAQFAIPAEIKDIKGLDLKSVGAMGMEGAVVKISTGADHDMTAMYKVNVEDLSQLLAYHEVFGKLNADGQAQSKGEIEIEVPGTSTMSEAESSPGHHACDICGKAFQFRYQLIVHRRYHGETKPYSCQVCGQSFANPVELSRHGKCHLAGDPVERHAKRLPQDKPYACTTCHKTFSRKEHLDNHVRSHTGETPYRCEYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHFMNHVMWHTGETPHQCELCGKKYTRKEHLSNHMRCHTNDTPFRCELCGKSFTRKEHFSNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCNFCSKSFTRREHLVNHVRQHTGETPFQCGYCPKAFTRKDHLVNHVRQHTGESPHKCSFCTKSFTRKEHLTNHVRQHTGESPHRCTYCAKSFTRKEHLTNHVRQHTGETPHKCTFCPRAFTRKEHLINHVRQHTGVTPHACSYCSKSFTRKEHLVNHVRQHTGETPFKCSFCSKSFSRKEHLTNHVNLHTGETPHKCPFCTKTFSRKEHLTNHVRIHTGESPHRCDFCQKTFTRKEHLTNHLKQHTGDAAHTCKICSKPFTRKEHLITHMRSHSCNEQPYSCGECGKSFPLKGNLMFHERTHQKGAGARPFRCEVCSKDFMCKGHLITHRRTHTESGAAPSTEPSPAEDCTAKCVKVEAVESLAMDSKPKVEEIRAAESIIVAHPQASPTNAAVMQIQNQQSRPIAVSSAGGITTATFTHSASNQHHTGAIAHHPVSVTY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00634709;
90% Identity: iTF_00143231;
80% Identity: -