Basic Information

Insect: Lysandra bellargus
Gene Symbol: ZFX
Assembly: GCA_905333045.1
Location: HG995321.1:15542765-15548732[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 27 9.1e-05 0.0075 17.3 1.2 1 23 249 271 249 271 0.98

2 27 1.6 1.3e+02 4.0 0.4 6 23 283 300 283 300 0.96

3 27 1.2 1e+02 4.3 1.5 1 23 309 332 309 332 0.90

4 27 0.00011 0.0087 17.1 3.0 3 23 353 373 352 373 0.98

5 27 0.00017 0.014 16.5 0.7 1 23 379 402 379 402 0.96

6 27 0.076 6.2 8.1 0.1 1 23 408 430 408 430 0.94

7 27 0.0013 0.11 13.7 0.1 1 23 436 458 436 458 0.94

8 27 3 2.4e+02 3.1 1.0 1 23 579 601 579 601 0.91

9 27 3.2e-05 0.0026 18.8 3.3 2 23 608 630 607 630 0.92

10 27 6.7e-05 0.0055 17.7 1.7 1 23 636 658 636 658 0.96

11 27 1.1e-05 0.00089 20.2 0.6 1 23 664 686 664 686 0.97

12 27 0.0024 0.2 12.8 0.1 1 23 692 714 692 714 0.98

13 27 0.02 1.7 9.9 1.7 1 23 720 742 720 742 0.95

14 27 0.34 28 6.1 6.0 1 23 748 771 748 771 0.92

15 27 1.4 1.2e+02 4.1 0.1 2 23 830 850 829 850 0.94

16 27 0.00024 0.02 16.0 0.3 1 23 856 879 856 879 0.89

17 27 3.8e-05 0.0031 18.5 1.5 1 23 885 907 885 907 0.94

18 27 0.00065 0.053 14.6 0.3 1 23 913 935 913 935 0.97

19 27 0.00068 0.056 14.6 1.0 1 23 941 963 941 963 0.96

20 27 0.0024 0.2 12.8 0.3 6 23 973 990 972 990 0.99

21 27 3.1 2.5e+02 3.1 0.5 1 23 1056 1077 1056 1077 0.86

22 27 0.022 1.8 9.8 0.5 3 23 1196 1217 1195 1217 0.95

23 27 0.0019 0.16 13.2 0.1 1 23 1223 1245 1223 1245 0.97

24 27 0.0064 0.52 11.5 0.0 1 23 1251 1273 1251 1273 0.97

25 27 0.00021 0.017 16.2 3.1 1 23 1279 1301 1279 1301 0.96

26 27 0.00014 0.011 16.8 0.4 1 23 1307 1329 1307 1329 0.96

27 27 0.00019 0.016 16.3 0.5 2 23 1335 1357 1334 1357 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	27	9.1e-05	0.0075	17.3	1.2	1	23	249	271	249	271	0.98
2	27	1.6	1.3e+02	4.0	0.4	6	23	283	300	283	300	0.96
3	27	1.2	1e+02	4.3	1.5	1	23	309	332	309	332	0.90
4	27	0.00011	0.0087	17.1	3.0	3	23	353	373	352	373	0.98
5	27	0.00017	0.014	16.5	0.7	1	23	379	402	379	402	0.96
6	27	0.076	6.2	8.1	0.1	1	23	408	430	408	430	0.94
7	27	0.0013	0.11	13.7	0.1	1	23	436	458	436	458	0.94
8	27	3	2.4e+02	3.1	1.0	1	23	579	601	579	601	0.91
9	27	3.2e-05	0.0026	18.8	3.3	2	23	608	630	607	630	0.92
10	27	6.7e-05	0.0055	17.7	1.7	1	23	636	658	636	658	0.96
11	27	1.1e-05	0.00089	20.2	0.6	1	23	664	686	664	686	0.97
12	27	0.0024	0.2	12.8	0.1	1	23	692	714	692	714	0.98
13	27	0.02	1.7	9.9	1.7	1	23	720	742	720	742	0.95
14	27	0.34	28	6.1	6.0	1	23	748	771	748	771	0.92
15	27	1.4	1.2e+02	4.1	0.1	2	23	830	850	829	850	0.94
16	27	0.00024	0.02	16.0	0.3	1	23	856	879	856	879	0.89
17	27	3.8e-05	0.0031	18.5	1.5	1	23	885	907	885	907	0.94
18	27	0.00065	0.053	14.6	0.3	1	23	913	935	913	935	0.97
19	27	0.00068	0.056	14.6	1.0	1	23	941	963	941	963	0.96
20	27	0.0024	0.2	12.8	0.3	6	23	973	990	972	990	0.99
21	27	3.1	2.5e+02	3.1	0.5	1	23	1056	1077	1056	1077	0.86
22	27	0.022	1.8	9.8	0.5	3	23	1196	1217	1195	1217	0.95
23	27	0.0019	0.16	13.2	0.1	1	23	1223	1245	1223	1245	0.97
24	27	0.0064	0.52	11.5	0.0	1	23	1251	1273	1251	1273	0.97
25	27	0.00021	0.017	16.2	3.1	1	23	1279	1301	1279	1301	0.96
26	27	0.00014	0.011	16.8	0.4	1	23	1307	1329	1307	1329	0.96
27	27	0.00019	0.016	16.3	0.5	2	23	1335	1357	1334	1357	0.95

Sequence Information

Coding Sequence: ATGAATATTGAGAGTGAAAAAATTCTTGTAAATTCAAGTGCTAATTTGTCGCAAGAGAGCCTAAATTTCGCGGAAACCTGCAATGTGTTGAACGGTCTAGAAAATTTGTCAAATGTCTGCCGAATATGTGCAAATGTAACTGAGTTTGTTATACCCATATTCATCGGTGAGGGTCTACACAATAACTTGGCGCAAAAAATTCAGCAACATCTTCCAATAAAGATATCAGAGGATGATGTTCTGCCGCATGTGGTGTGCTACCAGTGTGCCAGCACAATCCTCGCCTGGCATGACCTCGTGGAGTGTTGCCTCCAGGCTGACGTGACACTGCAGCAGCGAATATCTTCACTTACTAATGAAACAGAGCTGAAAAAAAATTCAAACCAAAGATTAGAGGATAATGAAGAAAGTTCTGCCAAAAAAGGGGAGGATAAACTTATAAGCCTAGTGTATGACATTCTTCGTGAGTACCTACAACTTATGGAATTAGATGAAAATAATATTATGGATTTAGATTATGTGTGCCAGGTCTGCACCCACAAACCTGCAGCTAAAACAATAGGCAACTTGGTGAAACACCTCCGGTTGTCTCATAGCACGGAACTCTGCAACTCGGAGTCTATTCGGAACTTCATCAGGAACAATATAACTTTTGAAGAAACTTTAAGCGCGGAAGATAAAGACGACCATGGGAGTGATACAGACAAAGGAATCGATAAAGAGGCCGGCACCGACTTGCCGGCATACTTCTGCCCCTACTGCGACAGTGCCTTCTCCACCCCCACTAGGCTGATACATCACATCAACAGACACATAGATATATCGACAGAGAACGTGCTAACATGCTGCGGGGAAAGCTTCGACAAAAAATCCTTTGCGCTCCACCTGCAGCGCAGGCACGTGGCGCGCGTCGTCGCGGGCCCGCACGTGTGCCGGAGCTGCTCCCACAGCGCGCGCACCGAGCACGATCTACAGGCGCACGTGGCCGCCGAGCACGGCGCGCCGCCCGTCGCCCGCCCCGAGCCGCGCCGTCGCCGCTCGCACGCGCCCGCCGCCTGCCCACGGTGCCGCAAGACATTCTCCAACAAACACAACATGCTGGTGCATCTGAGGTCCCACGACGCGAGCGAGCCGTTCGCGTGCGACAGATGCGACAGGCGCTACAGGACCCGGAGCGGCCTGAGCGAGCACCGCCGGATCGTCCACGAGGGCGTGATGCGGCACGTGTGCGCGACGTGCGGCGAGGCCTTCCCCACGCGCGGCGCGCGCGACGTGCACGCCCGCCTGCACTCCGGCGCGCGCCCCTTCGCCTGCGACTACTGCGGCAAGGCCTACCGCGCCAAGAACACGCTGGACCGCCACGTCGAGGCGCACCTGGACGTCCGGAAGTACCCGTGCGCGCCCCGCCCCGGCTCCGAGCCGGCGCCGAGCGAGGCGGCCGGGGAGCGCGCCGATCGCGACGACGACGACGAGCCCCCGGCGAGCGGGGTGGGCAGGAGGGCCGCCGAGCTGTACGGAAACTTCTACGGCGCCCTCGTAAATTTTCGGGACCATCTTGCCACCGAGCACGAGGGGAGCTCCCCGGACTCCGGCGACTCCGACGAGGGCGGGAGCGACGAGGCGGTCGGCGACGAGTACGACGACCTCACCCGGGGCGCGAGGAGGGCGGGGGGGAGCGCTGAGACCGAGCTCGAGCTCGCCCGCGCGCAGACGACGGTCGACGGGCGGGCGTACTACGCGTGCGGGACGTGCGGCAAGCACCTCGGCTCGGCGCAGACCTACCTGTTCCACCGGCGCATCCACACGGACGAGCGGCCCTGCGTGTGCCACGTCTGCGGCAAACGGTTCCGCACGCCCAACGGCCTGCGCCGCCACCTCACCGAGACCCACGAGCGCCGCCGGCTCCACGCCTGCGCGCTCTGCCACAGGACCTTCGCCAACTCCCAGAACCTCCGGGCGCACGCGCGCATCCACACCGGCGAGAAGCCGTTCGTGTGCGCGCAGTGCGGGAAGCGCTTCACGCAGAGTGGCTCCCTACACGCGCACGCGCGCGGCCACAGCGCGCTGTACCCGTACCGCTGCGCCGAGTGCGGGGCACAGTTCAAGCTGCGCGCCGGCCTCGCGCGCCACGCGCTGCGGCACACGGGCGAGCGGCCGCACGCCTGCGACGCGTGCGCGCGCGCCTTCCGCCACCGCCACGAGCTCGCCGCGCACGCGCTCACGCACACCGACGCCCGTCCGCACGCCTGTCGCCTGTGCGGCTCCGCCTTCCGCCAGCGCAAGGCGCTGCGCCACCACTGCAGGCGCGTCCACGAGACCGACGTCGCCGACGCGCCCGGGCCCGTCTTCGACCACGTCGGCCCGTACGATTCGAACGTAAAGGACGAGATCGGGGACGAGAGTCGATCGAGCGGCCCCGCGCAGCGAAAGCCGGCCGACGAGTCGAGGAACCCGACTACGCTCCCGAGCGACGGAAAAGAATACGTGGAGTGCACACTGTGCGACCAAAACGTCCCGGCCGCGTCCTGGCGCCGCCACCGGCGGTCCCATCAGGGCGGGCGGCCGCACAGCTGCCACGTGTGCGGGCTGGGGTTCGCCGACCGCGGGAACCTCGCGCGCCACGCGGCGGAGCGCCACCGCCGCCTGCGCCCGCACGCCTGCGCCCTCTGCGGCCGGACGTTCGCGCGCAAGTCGCACCTGCGGGACCACGCGGCGTCGCACTCGGCCGTGCGCGACCACGTGTGCGACGTGTGCGGCCGCGCCTCCAAGTCCGCCGCCGCGCTGCGCATGCACAAGAAGATGCACGACGACACGCTCGGGTTTCACTGCGCGTTCTGCGACGCTCGATTCAGGAGGAGGAGCCAGCTCGTGGCGCACGCGTCCGTGCACACCGGGGAGAGGGCCCACGCGTGCGCCTGCGGCCGGACCTTCCGTCTGCGCAGCCAGCTCTACGCGCACGCCCGCACGCACGACGACGGCCGACCGCGGGGAGACGGGCCGGGCCCCGATCCGCGGGACGATGTCGCGGGGCCGATCGACCGGCCCCACCCCGCCGAGGCGGCGGCCCCCCCTCCGGTGCCCCCGCGGACCTGCGCCTATTGCCGGGCGGAGTGCCCCGAGCCCCAGCTAAAGGAGCACCTGATATCGACGCACTCGGAGCTGCTGTTCCGCTGCGACGAGTGCGACAGCTACGTCGACCGCCAGGACTTCGTCGAGCACATGTCGCAGCACGCCGTCGAGTACGCCGCCGACGCGGAGGAGGCCCGCCCCGCGCCCCCGGACCCCGGGGGCCGGGAGGGCGAGCGCGCGGCGGACGGGGTCGAAAACGAGGACGGAGAAGCGACGGGAGAGGAGAGAGACGGGGGCGGCTCGGTGAACGGGGACGAGTTCTCGGACCGCAGCGACGCGGAGTACTTCGGCGAGCTGCCCGAATCCGTGTTCGAGGCCATCGAGGACTCGCAGGACACGCAGGCGGCCGACGACGGCGACCGCCTCTCGCGGGCCGACGCCGCGACCCCCGCCGGCCCCGCGGCGCCGCTCGCGGGACCCCCCATCGACGGGAGGAAAACGAAAAAGGAGCGGGCGTGCCCCGTCTGCTCGAAGGTGTACACCGCCAGCTCCAGCTACTTCTATCACGTGAAGCACGCGCACGGCGCCGCCCGGCAGCACGAGTGTGACGTCTGCGGGCGGAGGTTCGGCGCCAAGCCGACGCTGGCGCAGCACCTGCTCATCCACGCGGCGGAGCGGCCGTACGCGTGCGCGCAGTGCGGCGCCACGTTCCGCGCGCGCGCCGCGCTCTACGTGCACGAGCAGACGCACGGCGGGCGCAGGACGCACGCGTGCGGGGAGTGCGGGCGCTCGTTCCGCTGGCGCGCGCACCTCGAGCGGCACCGGCGGCGTCACGCGGGCGGGCGCGAGCACGCGTGCGACGCCTGCGGGCGGAGCTTCAACGTGCGCGCCGACCTGCTGCGGCACGCGCGCACGCACGCGGCGGCCGCGTTGCCGTGCCCGCACTGCGAGCTGCGGTTCGCGCAGCCCCGCTACCTGCGCGCGCACCTCAACAACAAGCACGCCGCCGAGGGAGGAGGAGTCGTGAAATGA
Protein Sequence: MNIESEKILVNSSANLSQESLNFAETCNVLNGLENLSNVCRICANVTEFVIPIFIGEGLHNNLAQKIQQHLPIKISEDDVLPHVVCYQCASTILAWHDLVECCLQADVTLQQRISSLTNETELKKNSNQRLEDNEESSAKKGEDKLISLVYDILREYLQLMELDENNIMDLDYVCQVCTHKPAAKTIGNLVKHLRLSHSTELCNSESIRNFIRNNITFEETLSAEDKDDHGSDTDKGIDKEAGTDLPAYFCPYCDSAFSTPTRLIHHINRHIDISTENVLTCCGESFDKKSFALHLQRRHVARVVAGPHVCRSCSHSARTEHDLQAHVAAEHGAPPVARPEPRRRRSHAPAACPRCRKTFSNKHNMLVHLRSHDASEPFACDRCDRRYRTRSGLSEHRRIVHEGVMRHVCATCGEAFPTRGARDVHARLHSGARPFACDYCGKAYRAKNTLDRHVEAHLDVRKYPCAPRPGSEPAPSEAAGERADRDDDDEPPASGVGRRAAELYGNFYGALVNFRDHLATEHEGSSPDSGDSDEGGSDEAVGDEYDDLTRGARRAGGSAETELELARAQTTVDGRAYYACGTCGKHLGSAQTYLFHRRIHTDERPCVCHVCGKRFRTPNGLRRHLTETHERRRLHACALCHRTFANSQNLRAHARIHTGEKPFVCAQCGKRFTQSGSLHAHARGHSALYPYRCAECGAQFKLRAGLARHALRHTGERPHACDACARAFRHRHELAAHALTHTDARPHACRLCGSAFRQRKALRHHCRRVHETDVADAPGPVFDHVGPYDSNVKDEIGDESRSSGPAQRKPADESRNPTTLPSDGKEYVECTLCDQNVPAASWRRHRRSHQGGRPHSCHVCGLGFADRGNLARHAAERHRRLRPHACALCGRTFARKSHLRDHAASHSAVRDHVCDVCGRASKSAAALRMHKKMHDDTLGFHCAFCDARFRRRSQLVAHASVHTGERAHACACGRTFRLRSQLYAHARTHDDGRPRGDGPGPDPRDDVAGPIDRPHPAEAAAPPPVPPRTCAYCRAECPEPQLKEHLISTHSELLFRCDECDSYVDRQDFVEHMSQHAVEYAADAEEARPAPPDPGGREGERAADGVENEDGEATGEERDGGGSVNGDEFSDRSDAEYFGELPESVFEAIEDSQDTQAADDGDRLSRADAATPAGPAAPLAGPPIDGRKTKKERACPVCSKVYTASSSYFYHVKHAHGAARQHECDVCGRRFGAKPTLAQHLLIHAAERPYACAQCGATFRARAALYVHEQTHGGRRTHACGECGRSFRWRAHLERHRRRHAGGREHACDACGRSFNVRADLLRHARTHAAAALPCPHCELRFAQPRYLRAHLNNKHAAEGGGVVK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01217675;
90% Identity: iTF_00935010;
80% Identity: -