Lmon033531.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Lymantria monacha
Gene Symbol
egg
Assembly
GCA_905163515.1
Location
LR991104.1:20350184-20407627[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 4.5 2.7e+04 -4.0 0.0 29 38 1690 1699 1666 1700 0.80
2 2 3.2e-14 1.9e-10 41.4 0.0 4 72 1731 1792 1728 1797 0.87

Sequence Information

Coding Sequence
ATGAGTGCATCAGGCGATTTGGACAGTAATAAAGACGAGGAAGACATATTTGACAAAGGTTCACAATTAACTATCACAGAAAATACATCAGAAAGTTCTAATAGTAAAACTAGCGACGCTTTGCAAACATTTGATAATTCTAAAGTCTCACCAATTATGAGCGAAGGAGTCACTGTAAGTAGTTTAGATATCAATACTAGTGGAAATCAAATAGAGAATGTATCATTAGAAACTGATGATGTCTTGTTAAAAACTATGTCCAATGATGCAAGTGAAAAGGCTATCGACAATGTGGACGTAGTTGATCAGCAAATCGATACTCCAGCTTCATTATCACATTCAATAAACGAAGGCAATGAACTAAATGCAGCTTCACAAGATAACAAGTTAAGATCTGATAAAGTACCTATTACTTCTAATCAAACTACAACTTTAAATGATGCTCTAGAAGAAACACTGTTAGATGTATCAGCTAATAGTGTGATCGAAACTGCAGACATTGAATCTTCGGATTTAACTTTGTTGAAGAATGAATCAGATATCCCTAAAGATAGAATTAGTGAGCATTCCTCAGAAAAGCAAGAAGTAGATGTAACAGATAAAAAAGATTCTGAAATTAATGCTTATACTGATGTTATAGATTCAGCTACCATCAGTGGTTTAGAGGATAGTCATATACCAATTGAGTTTAAATCTTCAGACTGTTCATTATCAAAAGTTATAGCTCCTGAAACAGGTGAAGCTGACAAAGAGAGAGTACAGACTGAAACTGTCATAGCTGATATAGATAAAGTAATAACTAGTACACCAAGTATTGTTCATGAAGATAGCACATTAGTATCTAACAATGTATCTCTAACATCTTATAAGCATGATACAACTGGAAATTCTGCTACTGAAATAGAGTTACCAAGAGGATCAGATGACAATGCCTATGGCATTGAAAATGATATGACATCAAAGGCAGAACTTATTtctgaaaataatgaaaaatctgTAACAAATGAAAGTGAAAAATTTGGCACTTTGTCATCTGAAAATAATGCCAGTCTAAATACTATGGTTGCTGAGACAACTGAACATAGTGACAACAATATAGTAACAGCAATAGACTCTCAAGATATCATAGTAACCAGTAAAGAAATTATAGCTGGTGAATGTGAATTAAGGTGTGACAATGGTTCAACATCTGATAATCAATTTGATAGTGCTAATACGTCAACAGAAGAAAGACTTTTATATGAATCAGATGATAATGTTATTGAGGCTGTAAATAACGTCTCATCAGCATCATTGCCGATTAATGAGTCAGAAGTTCCTGATGATTCAATTGTAGATAATATATCAGAAAAACAATTAACAGAAAATAATCTACCAACTACACTTTCAGAAGTACAAGAAGTGTCTGAAAGCATTTCAGAGACTGAAACTAGTTCTAAAGACATAATTAAACCTGTAACTGATGTGATTATGGATGAAATAGACGAAGAGGAAttaattaaagataaaaaaatcattgataCCAATGTGGAGATGGATAAAATTGGTAAAAGTATTAAAGCAGTACTCGAAACAGGTAAGTCTAGCACTGTTTCTGGTATGTCAACAAAAAATGATATAGTGGATGTACCAGAAGTTTGTAAAGCGCATGAAAAATCAACAATTTCTTTAGAAACAAATGAAGGAACTATTATAATGCCAGAAAGTACAGATTTACAATTTGAAGCTGTAAACGAAAATGTAAGTATTGCAACAATTTCTAGTGAAAATACTAACCAAGGTGATGAAGACCAGGCAAAAGCTGTACATAGTGATACTGAGAATTCATTTAACATAAGTAGTACAGATAACTCTCCTATTCATTTCAAAACCAGTCACAGACTACACAGACCTGATGTAATGCTGGAAATACCAACTCAAGAATTAATAGACATTGATGATGTGTTGGATAGTCCAAATGATTGCAGCTATGctgatgattttttaaataatagtaaaattgaTGATAATTCTGATCAAAATAAATCAAATGAGCTTATAGCAGAAGCAATAGATAAGACAAGTGATGAGAATTTATCAAACGTTACAAGCAATTTAGAAGAAAACTTACCTCAAGAAGTAGATGCCGTCACTGTTAAagGTCCTTTAATAGAAGACCCTCAACCTTCAACGTCAGGATCGTATAAATTGTGTGTGGACACATCTGATGATCTACCCGAGGTGTCCGATAGCTTAGGTCTACTAGCAGAATCTGAAAGGGTgcgagatgatgacgatgaagatGATGCGGccgatgaagatgatgatttcGATCACGATGAAAGCAGCAATCAGATGCTAACAGCTGAACATTCAGAAGATTCAAATGCACCGCATTCAGAAGCAGAACCGATGAGAGAACAAACTGAGACAAGAGAAGATGCAGATGATAAAATATCCAATGAGTCAGATGGTGATATTGATGATATCACTGAAGAACAAGCAAACAAAAACGAGTTTGATGCTGTAGAAATTGAAGAATATGAACTTGGTGATAATACTGATGTAGTTGCTGAAGAAGAAAGCGTCCTGTGCGAAGAGGAGGTTAAGAAGGCTGAAGAAGTTCATGAAAAATTGGATGATACACCGTGTTTGCCTGATGAATCAACAGAAGCGATACCAGAGGCAATGAACTCGGAAGATTCTGATACTTCAAAGACTATTGATAAAAATAACGATGATACAGTAATGTCCaaagaaaatgttattaaagaaaaagatgAAACTGTTGTATCGAAAGAGAAGGATAAACAAGAAAATGACAATGCTGTTTTAATAGCAGACGAAACTCCTAGCGCAGAGAAATCTTCAATTGATGATGACGTCATAGAACAACCAAATATTATACCAACATACAATGTGTTGGACTCTGATTCTGAAGATGATGCTCTTCCGGGTTCTGAACAGAAGAAGAAAGACAAAAAGACTGATGTAGCAGAAGTCTCGTCACAGAAGGCACATGAAGTAGTTATTGAAGACAAGACAAAGAAATTTGGAGATGGCGTTACGACTATTAATATACCAAAGGGAATAGAGGTTAGATCTACTTCGATTGCAGTTGGAAGTACTCCAGAGATCCATAAAACTCCAGGGAAGACCGTTATCAGTGGAGTCCTAAAAGTAACATCTTTGAAACCGCTTCCAAGATTGAATACCAGCGAGGTAACAATAAAGACTTCCAGTGGACCAGAGCAGACTCTACTCATACCAGAAGCTCAGGCACAAACTGAAGGTGGAACATTAGCGAAGACCGAACCTGTATACAATATAGACAGCGATGAGGAGGAAACTaaagAGTCAACGAAACCCGATAAGAAGACCAAGAAATGCATCAACAACTCTTGTTCAAGCGGTGTGAAGGTATACAAGGTGGCAGACGCTGAGACAGCAGCGTATTACGACGCAAGTAGGAAGCGAAGACCGTTGGTCTGTCAGCCTTGTGCTGATGCTGTACTAGCTTGGAAACAGagGCTTATCACTGGTATAAAGGACATGATACCTCTTACACAACTGGATATGAGCAGCAAGTGTCAATATTCAGTAGAGATTCTCGATTCGGAGTCGGAGGATGAAGAGCCAGCACCGATGGAAGAGCAAGTCAAGGAGGCGATAGGTGAAGATGCTGCCAGTTTCCTGGAGCGACATCTAGCGGATGTGTTCAACGAGACGTGGACCAAGTACTCTATGGATGAACGATTGAAAGACACGCAAGATGAATTAAATGCTGAAATAGAGTCTTTGGATGTTAAAAGGAAGGAGATCGATGATATGTTATCGGAGTGTCAACGTATGACCGATAAACTTCGAACGGATCTGTACGCGACCTTCGAGCCACGCATCCAGGAGGAGCCGTCGCTACTTATTATTGATAAGCCAGATTTTCgttaCATTGGTCCAGAACTGGGTTGTCCTGATCCATCCGATGTAATCAAGAATCCTGCCACCGCCAAGAGGAAGTTGAGTACAAATAACAACACACCAGCGAAACGTCCTGCAGTCATACCGTTAGGATACGCACCCTTAAACGACCCTAGACTAAAGaaagatGTTTCTGTCGTGAAGTTGTCTGCGGAATCACCACCGCCTGATTTACCCCCGCCTGGTGAACTGACACGAACGCCGCTCCGCCTTGATATGCAAGTGTACGCCATGAAGAACGCCTTCGGACCCTGGTTGAAAGGCAAGATTACCGAGATCATGCCCAAGGGTACTACTTCTGCTAACTTCACAGCATGTCGTGTACAATTCAATCACGTCTCGAAGAACAATAACAAGATATTACCAGGGAGGTGTATTGCCTATGCTGACCCACCAGAAGTCAGGATGACCATAGGTACCCGGCTCGTGGCACTATTCAAAGGTACAAGGTACCCATGTTATTCTTCCGGTGTCGTCGCTGAAGCACCAACACCTGTAAATAATTACAGATACTTGGTGTTCTTTGACGATGGTTATGCTCAGTACGTCAAGCACTCCCACACTCGATTGGTTTGTGAATGTTCACCCTTGGTGTGGGACGAGGTACACCCGTTCTCGCGGGAATTCGTCAAAGAGTACCTAATGGCGTACCCTGAGCGACCTATGGTACGGCTACATAAGGGGCAGCACTTCAAAACTGAATGGAATGGTAAATGGCTGGCGTCACGTGTTGCCAAAGTAGATGCTTCTCTGGTTGAGGTGGAGTTCTTGGGTGATGGACGGCGTGAATGGATATATCGAGGATCTACACGACTTGCTCCTCTATATATGGAGCTGAAAGCGGCTGAAAGGCACAGACCTCGACTGCTGTTAGGTAGTAGAGGTCGTCAGCAGCCACGGACTGACATGCCTTATGTGGAATACACAAGGTCCGAGGAGCAAAATACTAACAAACTCGTGGAGAATCTGCCAGACAACACTGGAATGAGTTTGCAACAACAGAATGAGgaGATACGTCGACAGCGGGCCGTGGCTAAGAAGTCCACTACTATGCCTTCGTTACAACAAGGACAGACTGGCGCAAGAGTACACACCGATCATCCCGATAGCGTCACCAGCAGAGTAGTGTACTATACTCCCAAGAGTGCGGTAAAACCTTACAAGTTGGTACCACATCATTGTTCACCGAAGTGCAAGCGTACAGATGTTCTATCTCTGAAGGAGTTGAGGACCTATAATCCATTGGCGAAGCCACTGCTCAGCGGCTGGGAGAGGCAAATATTGCGGTTCAAAGGTCAGAAGGAGGTGATGTATCGCGCGCCATGCGGACGTCGGCTCAGGAATATGAAAGAACTCCACCGTTATCTTCGTGCAACTGATAGCGAACTACCAGTGGACCTGTTCGACTTCTATTACGGAACACATTGTTTAGCTGAATTCCAAATATACAAGTGTCTCACAGGGAAGAAGGACTTATCTCACGGCAAAGAGAATGTACCAGTTCCGTGCGTCAATTATTATGACGAATCATTGCCGGAGTTCTGTTCGTACAACACTGAGAGGACTCCGACTTCCGGGGTGCCACTGAACTTGGACCCAGAGTTCCTGTGCGGATGTGACTGTACCGATGATTGTGAGGATAAAAGTAAGTGCGCGTGCTGGAAGATGACCCTGGAAGGTGCCCACACCATAGGACTAGAGGGGCCCAACATTGGTTATGAGTACAAACGACTCCCTGAGCCATTGGCCTCCGGGATATACGAATGTAATTCTAGatGTAAATGCAAGCAGACGTGTCTGAATCGTGTCGCTCAGCATCCTTTACAGTTGAAGCTACAGGTGTTCAAGACGCTACGTCGTGGTTGGGGCATCAGGGCGCTGAACGACGTGCCCAAGGGTGCGTTCCTATGCGTGTACGCTGGGAACCTTCTCACTGATGCAACAGCTAACTTGgaTGGTTTGAATGAAGGTGATGAATATTTGGCTGAGCTGGACTACATAGAAGTTGTAGAGCAGATGAAGGAAGGTTACGAGGATGACATACCCGAGGCTGATAAGAAATTGGACAAGAAATCATCGGACAAAACAAAAGTTGAAGACTCTCAAGATGAATCAGCTGCATCATCAGATGAAGATGAGAGCCACTCCAAGTACGATGAGCAAGACGACGACTTCAGACCTGGTCATATCGGCTCTGAGGTTACACAGTTCAGGAAAAATCTTCGTAAACGTAGCCGGGACGAGGAGAAAGGTGCCGAAGCTAAAGATAAAGAGAAGGACAATAAAGATAAGAATCCTGATGAGGATTGCATCACTATCAGTGATGATGAAGAAGtaCGAGAACCTTCGAGTTTTGCCGCGCAATCCGGTATGAGCAGCAATGAGTTTGTGCCCAAATACAAGTCGGTTCGCGCGTACTTCGGCGAGGACGAGGCGTGCTACATCATGGACGCTAAGGTTCAAGGCAACATAGGACGTTATCTCAATcACTCCTGTTCCCCCAATGTGTTCGTTCAGAATGTATTCGTTGATACACACGATCCAAGATTCCCTTGGGTAGCTTTCTTCGCGCTATCCCACATTAAGGCCGGCACTGAGCTGACGTGGAACTACAACTATGATGTAGGCTCCGTGCCCGGGAAGGTATTATATTGCTACTGCCAATCGCGCAATTGTAGGggaagattattgtaa
Protein Sequence
MSASGDLDSNKDEEDIFDKGSQLTITENTSESSNSKTSDALQTFDNSKVSPIMSEGVTVSSLDINTSGNQIENVSLETDDVLLKTMSNDASEKAIDNVDVVDQQIDTPASLSHSINEGNELNAASQDNKLRSDKVPITSNQTTTLNDALEETLLDVSANSVIETADIESSDLTLLKNESDIPKDRISEHSSEKQEVDVTDKKDSEINAYTDVIDSATISGLEDSHIPIEFKSSDCSLSKVIAPETGEADKERVQTETVIADIDKVITSTPSIVHEDSTLVSNNVSLTSYKHDTTGNSATEIELPRGSDDNAYGIENDMTSKAELISENNEKSVTNESEKFGTLSSENNASLNTMVAETTEHSDNNIVTAIDSQDIIVTSKEIIAGECELRCDNGSTSDNQFDSANTSTEERLLYESDDNVIEAVNNVSSASLPINESEVPDDSIVDNISEKQLTENNLPTTLSEVQEVSESISETETSSKDIIKPVTDVIMDEIDEEELIKDKKIIDTNVEMDKIGKSIKAVLETGKSSTVSGMSTKNDIVDVPEVCKAHEKSTISLETNEGTIIMPESTDLQFEAVNENVSIATISSENTNQGDEDQAKAVHSDTENSFNISSTDNSPIHFKTSHRLHRPDVMLEIPTQELIDIDDVLDSPNDCSYADDFLNNSKIDDNSDQNKSNELIAEAIDKTSDENLSNVTSNLEENLPQEVDAVTVKGPLIEDPQPSTSGSYKLCVDTSDDLPEVSDSLGLLAESERVRDDDDEDDAADEDDDFDHDESSNQMLTAEHSEDSNAPHSEAEPMREQTETREDADDKISNESDGDIDDITEEQANKNEFDAVEIEEYELGDNTDVVAEEESVLCEEEVKKAEEVHEKLDDTPCLPDESTEAIPEAMNSEDSDTSKTIDKNNDDTVMSKENVIKEKDETVVSKEKDKQENDNAVLIADETPSAEKSSIDDDVIEQPNIIPTYNVLDSDSEDDALPGSEQKKKDKKTDVAEVSSQKAHEVVIEDKTKKFGDGVTTINIPKGIEVRSTSIAVGSTPEIHKTPGKTVISGVLKVTSLKPLPRLNTSEVTIKTSSGPEQTLLIPEAQAQTEGGTLAKTEPVYNIDSDEEETKESTKPDKKTKKCINNSCSSGVKVYKVADAETAAYYDASRKRRPLVCQPCADAVLAWKQRLITGIKDMIPLTQLDMSSKCQYSVEILDSESEDEEPAPMEEQVKEAIGEDAASFLERHLADVFNETWTKYSMDERLKDTQDELNAEIESLDVKRKEIDDMLSECQRMTDKLRTDLYATFEPRIQEEPSLLIIDKPDFRYIGPELGCPDPSDVIKNPATAKRKLSTNNNTPAKRPAVIPLGYAPLNDPRLKKDVSVVKLSAESPPPDLPPPGELTRTPLRLDMQVYAMKNAFGPWLKGKITEIMPKGTTSANFTACRVQFNHVSKNNNKILPGRCIAYADPPEVRMTIGTRLVALFKGTRYPCYSSGVVAEAPTPVNNYRYLVFFDDGYAQYVKHSHTRLVCECSPLVWDEVHPFSREFVKEYLMAYPERPMVRLHKGQHFKTEWNGKWLASRVAKVDASLVEVEFLGDGRREWIYRGSTRLAPLYMELKAAERHRPRLLLGSRGRQQPRTDMPYVEYTRSEEQNTNKLVENLPDNTGMSLQQQNEEIRRQRAVAKKSTTMPSLQQGQTGARVHTDHPDSVTSRVVYYTPKSAVKPYKLVPHHCSPKCKRTDVLSLKELRTYNPLAKPLLSGWERQILRFKGQKEVMYRAPCGRRLRNMKELHRYLRATDSELPVDLFDFYYGTHCLAEFQIYKCLTGKKDLSHGKENVPVPCVNYYDESLPEFCSYNTERTPTSGVPLNLDPEFLCGCDCTDDCEDKSKCACWKMTLEGAHTIGLEGPNIGYEYKRLPEPLASGIYECNSRCKCKQTCLNRVAQHPLQLKLQVFKTLRRGWGIRALNDVPKGAFLCVYAGNLLTDATANLDGLNEGDEYLAELDYIEVVEQMKEGYEDDIPEADKKLDKKSSDKTKVEDSQDESAASSDEDESHSKYDEQDDDFRPGHIGSEVTQFRKNLRKRSRDEEKGAEAKDKEKDNKDKNPDEDCITISDDEEVREPSSFAAQSGMSSNEFVPKYKSVRAYFGEDEACYIMDAKVQGNIGRYLNHSCSPNVFVQNVFVDTHDPRFPWVAFFALSHIKAGTELTWNYNYDVGSVPGKVLYCYCQSRNCRGRLL*

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-