Basic Information

Insect: Lygus lineolaris
Gene Symbol: Zfa
Assembly: GCA_030264115.1
Location: JAEMON010000006.1:22803614-22831210[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 2 1.9e+02 3.6 1.9 1 21 364 384 364 388 0.90

2 15 0.00014 0.014 16.6 0.6 2 22 445 465 444 468 0.89

3 15 3.3 3.3e+02 2.8 5.0 2 19 484 501 483 506 0.90

4 15 0.013 1.3 10.4 0.9 1 23 511 535 511 535 0.90

5 15 0.0083 0.81 11.0 1.0 1 20 572 591 572 593 0.93

6 15 0.065 6.3 8.2 0.5 1 23 624 646 624 646 0.96

7 15 2.1e-05 0.0021 19.2 3.2 1 23 656 677 656 677 0.98

8 15 6.2e-06 0.00061 20.9 1.9 1 23 683 706 683 707 0.94

9 15 0.066 6.4 8.2 0.1 3 23 719 740 717 740 0.94

10 15 8.8e-06 0.00086 20.4 0.8 1 23 747 769 747 769 0.99

11 15 7 6.8e+02 1.8 0.4 9 23 784 798 774 798 0.74

12 15 0.0023 0.23 12.8 5.0 1 23 804 827 804 827 0.97

13 15 0.083 8.1 7.9 8.4 2 23 834 855 833 855 0.97

14 15 0.00013 0.012 16.7 2.6 1 20 861 880 861 882 0.95

15 15 5.3 5.1e+02 2.2 0.4 1 23 892 917 892 917 0.93

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	2	1.9e+02	3.6	1.9	1	21	364	384	364	388	0.90
2	15	0.00014	0.014	16.6	0.6	2	22	445	465	444	468	0.89
3	15	3.3	3.3e+02	2.8	5.0	2	19	484	501	483	506	0.90
4	15	0.013	1.3	10.4	0.9	1	23	511	535	511	535	0.90
5	15	0.0083	0.81	11.0	1.0	1	20	572	591	572	593	0.93
6	15	0.065	6.3	8.2	0.5	1	23	624	646	624	646	0.96
7	15	2.1e-05	0.0021	19.2	3.2	1	23	656	677	656	677	0.98
8	15	6.2e-06	0.00061	20.9	1.9	1	23	683	706	683	707	0.94
9	15	0.066	6.4	8.2	0.1	3	23	719	740	717	740	0.94
10	15	8.8e-06	0.00086	20.4	0.8	1	23	747	769	747	769	0.99
11	15	7	6.8e+02	1.8	0.4	9	23	784	798	774	798	0.74
12	15	0.0023	0.23	12.8	5.0	1	23	804	827	804	827	0.97
13	15	0.083	8.1	7.9	8.4	2	23	834	855	833	855	0.97
14	15	0.00013	0.012	16.7	2.6	1	20	861	880	861	882	0.95
15	15	5.3	5.1e+02	2.2	0.4	1	23	892	917	892	917	0.93

Sequence Information

Coding Sequence: ATGAGTGATGATGACGACGAAGATACTCATTTCTGCTTGAGGTGCAACACAACCATCACAGGATTGGATGCTTATGTGGCTCATAGGAAATCAAGATGCAATCAGGCCCAAACGTCTGACAGATATGGCCCAGGCCCTTCTGGCCTGCAGGTGGACACCTGCCCTGACGATTCCCCAGTTACAGAAACACCAAGGATCCCTGATGCAGATCTACTGCTCCATCCTGGTCTTACTCACCCAACGTTGACCCCTCCAAGCCCACATAAAGGGGAACCTCAAGCTGATGATTACTTCTTTTCATCTCTGTGCCTCCAAAGTAGCTCCAAGATGGGTGAACCTGCATCTGCAATGAAACACCATGGAGTTCTGACTCGCAGCAAGATTCTGGAGAGAAACATTGTTAGGGAAGAAAAACCATCTGTTCTCCAAAGTGAAGAAGTGGAAGCGCAGGAGGAGAGTGAATCAGAAGATTCCGACGATGAAAGGCACCCCCCACCTACAAGTGGCGGCAAATGGTTACCGGGATTCCGACCTACTCATCGAGCAACATCTATCTTGTGGAAATCAGCTATCACGCCCGAACACAAGCCTGCAGAGACTGAGACAAGACCAGAGCATCCAACAGCAGTAAGGCGTCCTCTAGCCCCACCACCCAGCCACACACGGGGGAAGTGGGATTCTTCCGAAAGACCATGGGGACCACTAAGGAAGCCCAACGCATACTGGTGTGGACCATGCAACCGTCGTCTCAGCTCCAGAATCGTTTACGATAGGCATATCAAAAGCGAGCTACATTTCAAAAGGACCAACCCTTGGCGAACACAAGTGGCTCTTGGGAAGAGGGCTAGAAGAAGGACGCGAATAGCTGAAGAATCTACTCTCCGAATGATGAATCGGAAACTTCCAAGAGAGGTCAAAATCGCAAAGAGACGCCGTGGAGCGACCGTCTGCGACGTCTGTAATTACAGAGTCGCACCGCATCTTATGGGGAAACACCTCATATCCCACTACCACTGCAACCACCCGCGGAACGACAAGAACAACGAGATGGTCCTCAAGCACATACTGAGCATAGTGCACCAAGCCCCGTTTCAATGTGGCCTGTGCAAATTTTATTGCAACACTCAACAGGCATTTTTAACACACTGGGCGTCCGAGATGCATAGGAAGAATGACGTTAAGAGATCAGGCGTCTACTGGTGCCCCAACTGCAACTTCGAAGCAGATTCCAGTGTTGATATGAGCTGCCATCTCGTCGACGACTTGCACCGTGACCGTGTGATGATAGTAAATCATTCCGTGCCAATCATCATCCAGAAAATCACCCCTCTTCAATGTGAAGTTTGTGGCAAATGTTTTCGCTACAATGTACAAGTCCGCGCGCACAGCAGAATCTGGGGCCATGAGCAGACCAGAAGCACAGCATCCAACAGTTACCAAGAAGCCTTGAGTTGTTCGGAATGTCCTTACAAATGCAActcgttggtctcattccaaAGGCACTGTTACATGAAGCACAAAAAAGTGCCATACTTCTGCCGGAGATGCGAATTGAGTTTCAAGAGCTCAGCAGAAGTCAAGGCTCATCGCAAATCCACCGCACATCGCGACGCTGCCGGTCCGAAAGCGAGGCACTGCCCCCATTGCCGGATGTCGTTTCTCAAGATATCTTCTTTGAAATGTCACTTGGAAGAACGTCACCCTGAATTGAAACATAGATGCCTGAAATGTGGCGAAAGGTTCACTTTGAAACAGCAACTCTCTCAACATGCGACGTCTTGTCAAATGGTGAACAGAAGCAATCCAGAAAATATAAATGATTCTGAGACAGCTGTATGTTTGGACGGAATCCACCAACAGGAGAAAGACTTCAGTTGTGATAGATGCCAGTTCTCTGGGAAAACAGAGTCGGAGCTTTTGGTCCACAAATTGCTGCATGATAACGCTGAATCAACAACGGGGAAGTTCAAATGTCCATACTGCAATAAGACGTTCAGTGATTCGTACATGAAGAAACACATGATGACTCATACTTCAGAACGCCCATACACCTGCGAAATCTGCAATTTCAGTTTCAGCCGTCAGGACACATTGAATCGCCATGTGGTCAAGATCCATCATATAGAAACGGGcaacttgaaaatgaaactcGATTGTGGTTTGtgtgaaaaacaattttcttcgcCGCTCGTTTTGGACCGCCACGTAAATTCCACCCACGGTAACCGAAAGAGATCGTTCAAGTGTTCGGAATGTGATCAAGCTTTCTACGAAAAGGGTACTCTGGATCGTCATATGCAAACTCATTTCGGGAAGAAATTCCACTGTTCGGAGGAGGGCTGCATTTTCAACGCGAGATCTCTGGGAGAACTGAAAATCCACGCAAGAACGCATTCGGAATCCAGAGAATTCCACTGTCAGCAATGTTCGTATTCTTCCAAAACCAAGAACCAGCTTTCCAAGCACATGAAATCAGTTCACATGCCCAAGGGCAAGTTGAAGTGCCCGAGGTGCCATTTCACTTGCCAAACCGGCACTCATCTCAAACGCCACCTGAGGATGCATTCAGGCTCGAAACCTTATCAGTGCCCTCATTGCTCGTTTACCTGCACTTCATTGgaCAATCTCCGGAAGCatataatttattccaaaatacATCCCGGCAAAAGCGTCTACGAGTGTCAAACGGATGGCTGTTCCTTCGAGACGAACTTATCCAAGGACTTCAAGAGTCATCTGGTCAGGGCGCACAACGTTCTGATGAAAGACGCCATGGCTCACGTAGCCGGCATTTACAAACCCAATGTTGACACTTTCTCGCCCCTCGGAGGTGGTAAAATACACGAAATGAGGCGCAGCGAGGGAGACCACGATGAGGATGCCAACCGGACTGACGTGGCAGAGGACGTGGTGGAGGCGACGACGCTTCAAGAGTTCGTCTACAGCACTGACGCCGTGGAAGCTGACGCCAGACTCCCGACGCTGGCGTCGGTCGCGCTGACGCCCGCCAAAACCGAAGAAGACATCATCTTCATCCACATCGGCCCCGACGAGCAGCCCTTCGATCCCCACATGTTCCACCAGAGCTTCCCAATAATCGAGACTTTTCCTGGTCAGCTGATGAATGATAATGTGGAAATTGAAACTACTAGTACCCACGAAGAAAACGCCTAG
Protein Sequence: MSDDDDEDTHFCLRCNTTITGLDAYVAHRKSRCNQAQTSDRYGPGPSGLQVDTCPDDSPVTETPRIPDADLLLHPGLTHPTLTPPSPHKGEPQADDYFFSSLCLQSSSKMGEPASAMKHHGVLTRSKILERNIVREEKPSVLQSEEVEAQEESESEDSDDERHPPPTSGGKWLPGFRPTHRATSILWKSAITPEHKPAETETRPEHPTAVRRPLAPPPSHTRGKWDSSERPWGPLRKPNAYWCGPCNRRLSSRIVYDRHIKSELHFKRTNPWRTQVALGKRARRRTRIAEESTLRMMNRKLPREVKIAKRRRGATVCDVCNYRVAPHLMGKHLISHYHCNHPRNDKNNEMVLKHILSIVHQAPFQCGLCKFYCNTQQAFLTHWASEMHRKNDVKRSGVYWCPNCNFEADSSVDMSCHLVDDLHRDRVMIVNHSVPIIIQKITPLQCEVCGKCFRYNVQVRAHSRIWGHEQTRSTASNSYQEALSCSECPYKCNSLVSFQRHCYMKHKKVPYFCRRCELSFKSSAEVKAHRKSTAHRDAAGPKARHCPHCRMSFLKISSLKCHLEERHPELKHRCLKCGERFTLKQQLSQHATSCQMVNRSNPENINDSETAVCLDGIHQQEKDFSCDRCQFSGKTESELLVHKLLHDNAESTTGKFKCPYCNKTFSDSYMKKHMMTHTSERPYTCEICNFSFSRQDTLNRHVVKIHHIETGNLKMKLDCGLCEKQFSSPLVLDRHVNSTHGNRKRSFKCSECDQAFYEKGTLDRHMQTHFGKKFHCSEEGCIFNARSLGELKIHARTHSESREFHCQQCSYSSKTKNQLSKHMKSVHMPKGKLKCPRCHFTCQTGTHLKRHLRMHSGSKPYQCPHCSFTCTSLDNLRKHIIYSKIHPGKSVYECQTDGCSFETNLSKDFKSHLVRAHNVLMKDAMAHVAGIYKPNVDTFSPLGGGKIHEMRRSEGDHDEDANRTDVAEDVVEATTLQEFVYSTDAVEADARLPTLASVALTPAKTEEDIIFIHIGPDEQPFDPHMFHQSFPIIETFPGQLMNDNVEIETTSTHEENA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00145904;
90% Identity: -
80% Identity: -