Lhir006048.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Lycia hirtaria
Gene Symbol
-
Assembly
GCA_947563715.1
Location
OX387377.1:10385665-10403881[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.0001 0.0082 17.2 0.1 3 23 137 157 136 157 0.97
2 18 9.3e-07 7.5e-05 23.6 1.2 1 23 163 185 163 185 0.99
3 18 5.8e-06 0.00046 21.1 2.7 1 23 191 213 191 213 0.99
4 18 3.8e-06 0.00031 21.7 2.6 1 23 228 250 228 250 0.98
5 18 8.6e-05 0.0069 17.4 0.6 1 23 265 287 265 287 0.98
6 18 5.3e-05 0.0042 18.1 3.1 1 23 302 324 302 324 0.98
7 18 3.7e-07 3e-05 24.9 1.5 1 23 339 361 339 361 0.99
8 18 6.4e-05 0.0052 17.8 0.2 1 23 368 390 368 390 0.97
9 18 1.2e-05 0.00093 20.2 2.1 1 23 396 418 396 418 0.99
10 18 0.037 3 9.1 1.8 1 23 425 447 425 447 0.98
11 18 6.2e-07 5e-05 24.2 2.3 1 23 453 475 453 475 0.99
12 18 0.26 21 6.4 1.1 1 23 482 504 482 504 0.98
13 18 2.5e-06 0.0002 22.2 1.5 1 23 510 532 510 532 0.99
14 18 0.00031 0.025 15.7 0.4 1 23 539 561 539 561 0.99
15 18 2.5e-06 0.0002 22.2 2.3 1 23 567 589 567 589 0.98
16 18 0.0021 0.17 13.1 0.3 1 20 595 614 595 617 0.93
17 18 4e-05 0.0032 18.5 1.4 2 23 624 645 623 645 0.96
18 18 3.6e-06 0.00029 21.7 1.4 1 23 651 674 651 674 0.97

Sequence Information

Coding Sequence
ATGTTTGAACAACAAATCAAAGCTGAACCGATGAGTTTTTACTCGTCGCACCAGCATGTGCACAGCGGCCCCCCAACCATAGTCAGGTCGGATTCCTCTCACCCTATCATCAACATGAACCAGCATCATCCGTTGTCGCATCTGCCGCACCAAGAGGATTCGAAGGACAGCCTGATAATACAACAACAAGTACAACACCAAGATCTCATGGAACAACACCAGCAGCAGGAGATGCACCAACAACAAGACGATGAGCTGAGCTTTAAAGGAATGGAAGATGAAGGTGTTGATATGGATATGGATGGCAGACAGTGTTCACAGGGTATGGGGGTTGATATGGGATCAGTTCAAACTAAAATGGAAGTAGCGAACGGCGGGCCAAACACACCTCGTTCAAAGCCGCAAGCCTGCAAGGTTTGCGGCAAAGTCCTTTCGTCCGCTTCATCATATTACGTCCACATGAAGCTTCATTCGGGAAACAAGCCTTTCCAATGCACAGTTTGCGACGCAGCTTTTTGTcgcaagccgtacttggaagtgcatatgcgtacgcacacaggtgaacggcccttccaatgcgatctgtgcctaaagcgcttcacgcagaaatccagccttaacacacacaaacgtgtgcacacggatgagcacatgcgcgcgttgatggtgaaggaccggccctacaagtgtgagctctgtcagatgcggttcacgcagagctccagcctcaaccgacacaagaaaatacacacggAGGAAcacagacgcgcgctgctggctaaggaacggccctaccagtgcggcatctgctatgtgcgattcacccagaaatcgagtctgggccggcacggaaaaatacacaccgAGGAGCACAGACGAGCCCTGTTAGAGAAAGTgcggccgtaccagtgccacatctgttttatgcgcttcactcagaagtccagcctGGGACGCCATGGGAAAATACATACTGAGGAGCACATCCAATCGCTGATCAACAAAGTgcgcccctatcagtgcgacatctgtgacaagcggttcacgcagaagtccagccttggcactcataaacgtatacacaccgtgcaagggcggccgttcgcgtgcgggcattgcccggcggccttcgcccgacgcccctacctggacattcacatgcgcacgcacacaggcgagcggccgtatcagtgcgacgcgtgtctgaagcgcttcacgcagaagtccagcctcaatattcataagaggacgcacacagtccagggcagaccgttccagtgcctgtcgtgccccgccgccttcacctgcaagcaatacctggagattcacacgcgcacccacaccggcgaacgaccgtatcagtgcgacatctgcctgaagcgcttcacgcagaaatccagtctcaacattcacaagcggacgcactcagtgcagggtcggccgttccagtgcctcgcgtgccccgccgccttcacctgcaagcagtatctcgagatccacaaccgcacacacaccggcgagcgcccctaccagtgcgacgtctgcctcaagagattcgcgcaaaagtctactcttaatatacacaaacgaacgcacacagtgcaagggcggccctaccagtgcgcggagtgtccggccgcgttcacttgcaagccctacctggagatacacatgcgcacgcacaccggagaacgacccttcgagtgcaatgtctgttacaagcgctttacgcagaaatccacgctcaacatacacaagcgtatacatactgGTGAACGCCCATATGCTTGTGATATCTGTCAGAAACGTTTTGCCGTGAAGAGTTATGTAACAGCTCACAGATGGTCTCACGTAGCCGACAAGCCATTGAACTGTGACCGGTGTTCAATGACTTTCACTTCCAAATCTCAGTTCGCACTTCACATCCGCACGCATTCTACGGGCCCGTGCTACGAATGTAGCGTATGCGGACGCACCTTCGTGAGGGACAGCTACCTTATACGGCATCACAACCGTGTACACCGCGAGATGAGCCACAGCCTGTCCACAAACAGCATCACCAATATCAGCAGTGTAGCGACCAACACAAACTCCAACAATGGCAACTACGACTCGCCCGGCGTCTGTGACTTGAGCTTTGTACCGATGGTAAACCGTTACATGACATCGCAAGGCACGCAGGTGTCGATGCAAGACTCGCAGAGCAAAATGTCGGCCATGTCACCGCAATCCATCGCCTCTATTTCATCACCTCCTCCGCCGCATACCCCAACGCCCCAGCCCCAGCAAATGTCGAGTCAGATGCATCTTGCAGACTGA
Protein Sequence
MFEQQIKAEPMSFYSSHQHVHSGPPTIVRSDSSHPIINMNQHHPLSHLPHQEDSKDSLIIQQQVQHQDLMEQHQQQEMHQQQDDELSFKGMEDEGVDMDMDGRQCSQGMGVDMGSVQTKMEVANGGPNTPRSKPQACKVCGKVLSSASSYYVHMKLHSGNKPFQCTVCDAAFCRKPYLEVHMRTHTGERPFQCDLCLKRFTQKSSLNTHKRVHTDEHMRALMVKDRPYKCELCQMRFTQSSSLNRHKKIHTEEHRRALLAKERPYQCGICYVRFTQKSSLGRHGKIHTEEHRRALLEKVRPYQCHICFMRFTQKSSLGRHGKIHTEEHIQSLINKVRPYQCDICDKRFTQKSSLGTHKRIHTVQGRPFACGHCPAAFARRPYLDIHMRTHTGERPYQCDACLKRFTQKSSLNIHKRTHTVQGRPFQCLSCPAAFTCKQYLEIHTRTHTGERPYQCDICLKRFTQKSSLNIHKRTHSVQGRPFQCLACPAAFTCKQYLEIHNRTHTGERPYQCDVCLKRFAQKSTLNIHKRTHTVQGRPYQCAECPAAFTCKPYLEIHMRTHTGERPFECNVCYKRFTQKSTLNIHKRIHTGERPYACDICQKRFAVKSYVTAHRWSHVADKPLNCDRCSMTFTSKSQFALHIRTHSTGPCYECSVCGRTFVRDSYLIRHHNRVHREMSHSLSTNSITNISSVATNTNSNNGNYDSPGVCDLSFVPMVNRYMTSQGTQVSMQDSQSKMSAMSPQSIASISSPPPPHTPTPQPQQMSSQMHLAD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01246112;
90% Identity
iTF_00649330;
80% Identity
-