Lfer003882.1
Basic Information
- Insect
- Luffia ferchaultella
- Gene Symbol
- Hr39
- Assembly
- GCA_949709985.1
- Location
- OX453242.1:22092657-22110051[+]
Transcription Factor Domain
- TF Family
- SF-like
- Domain
- zf-C4|SF-like
- PFAM
- AnimalTFDB
- TF Group
- Zinc-Coordinating Group
- Description
- The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 4 0.17 2.8e+03 -1.8 0.1 53 129 107 182 72 229 0.51 2 4 0.0032 52 3.9 7.5 59 163 226 331 173 385 0.74 3 4 2.8e-08 0.00046 20.6 0.1 1 21 468 488 468 504 0.90 4 4 3.4e-63 5.5e-59 201.4 0.0 145 408 514 791 498 791 0.82
Sequence Information
- Coding Sequence
- ATGGCGAGCGAGGGGGACACAGTCAAAGTGGAGGGCGCACACGTGTCCGTCACTACTATAGGCATGTCCGGTCCCGAAACAAGTAATGGCCAGTTCTCGTACAGCTCGAGCGGCGTCCGCATCAGCGTGTCCTCGGAGCCCCACGACGAGGATTCCACTGACGCCGAGATATCGAAAATTGACTTCGCGCAACATTACTACGAGGTAAACATGCGCAACAAAAAGAAGCGTCCTTCGAGCGGCGCGTGCACGGAAAGCGGAGGCAGTTCCGGAGGCGTTGCGCTGGAGCGCGAGCGGCCTATGTCCTGGGAGGGCGAACTCTCTGACTCAGAAATGGTCATCGATACTCCTAACCATAATGATGAGAACAGCAGCTCCCTGGATTTACAATCATCGAGAGACTCAATCGAAACTTTGAGGAATGTGACTATCAAAACTGAACCGATGAAAGCGGATAGGCTGGAGGCCTTCCAGTCGTTGGACGACCAGCACGTCTTGGATCTGAAGTACAAGTCAAACTTGTCACAGCCCTTGCAGCAGCATCAGAGAAGTCTCAGTATGAATAGGATATCAGTGTTGACCGACACCGCTTCTCTATCATTAGCCAGGCGGCCTTCGTCTCCTTCAGCTAATGGCAAATCTTCTTTAGTACTTAGTTCTGACCAAAAGAACATTCCTGTGATCATCCCGGCGTCTGCCAATTCGGAGGTTCAGAATCTTACTGTAAAGAAGGAAAACATTCCCCAACAAACTCAATTGTCAGAGTTAAAATGCGAGCCATCATCGGTTCCGATGGACAAGTTGCTGGGTGCATTACATGGCTCGCCACTGTTGGGTCGACTGCCGCGCGTGTTATCCAGTGCGAGCACCGACTCTGCTGTACATTCTATGTATACGCACAGCGTATATAGCAGTCCATCAGCGAGCCCTAGGGCGTCGCGACAATACACACCGTCACTCTCTCGTAACAACAGTGACGCGTCGCACTCATCATGCTATTCCTACAGTTCAGAGTTTTCGCCTACACACTCGCCTGTACAGaGTCGCCATCCCCATGGCGTCGTGTATAGAGAAGCGACAGCCGCTAGTGGCGTGTTCCCTGCTTCGCCCGCTCAAGACGATGACGCTGAGTTGTCCGAAGACAGGTTACACCATCACCAGGGCGTGAGCAGACAACAGCTGATTAATAGCCCATGTCCGATCTGCGGCGACAAAATCAGCGGTTTCCACTACGGAATCTTCTCCTGTGAATCGTGTAAGGGCTTCTTCAAGCGCACAGTACAAAACCGAAAAAACTATATGTGCCTACGTGGCGGGAACTGCCCCGTCACTGTGGCGACTCGCAAAAAGTGCCCAGCTTGTCGTTTCGATAAATGCCTCGGCTGTGGAATGAAATTGGAAGCGATCCGCGAGGACCGTACGCGTGGCGGGCGCTCCACATACCAGTGTTCATATACACTGTCCGGCGCAGCGTCAACAGGATCGCTTCTTTCTGCGCACGCACCGGCGACTTTAAGACATGCTACTAGTCTCAACTCGGTGAATGGCCCAGCGTCATACAACAGCAGAGGGGAATCTAGTAGTAGCCGCGCGACGCCAGATATACCGCCTCTTCTACAGGAGATAATGGACGTCGAGCATCTATGGCAATACAACGAATCCGAACTCTCCCGTCTTGGGAGAGGGAGTGGGGGTAGTGGTGGCAGCGCGGCTGCCAATCCACTGCTCGCTGCATCAGGCATCACAGCACATAGCACCAACCCTGACTTCTTAGCCGATTTGTGTAATATAGCCGATCATAGACTGTACAAGATCGTCAAATGGTGTAAAAGCTTGCCGCTGTTTAAGAATATATCGATCGACGACCAGATCTGTCTGCTGATCAACAGCTGGTGCGAGCTGCTCGTGCTGTCGTGCTGCTACCGCGGCGTAGGCTCGCCGGGTGAAGTACGAGTCGGTGGTTCGGCGCATGGAATCACGCTACAACAGAGTGCCAAATTGGGTCTGACGCCATGTATCGAACGCATGCTGAGCTTCACGGAGCACTTGCGGCGGTTGCGTGTCGACCGTTACGAGTACGTAGCGCTCAAAGTTATCGTACTTCTAACCTCTGACGCTCCGGAACTCCGCGAAGCAGAGAAAGTGCGGGCGTCGCAAGAGAAAGCGTTAGCGGCACTGCAAGCGTACACAGCTGCTCACTCGCCTGATGCACCAGCCAAGTTCGGAGAGCTGTTGCTACGCATACCCGAACTGCAAAGAACTTGCCAGTTTTTCATGCAAGTTGGCAAAGAGATGTTGAATCCAGCCAACAAAAGCAAAGACGGAGAAGGTCCTAGCTTCAATTTACTCATGGAGCTATTAAGAGGTGATCACTGA
- Protein Sequence
- MASEGDTVKVEGAHVSVTTIGMSGPETSNGQFSYSSSGVRISVSSEPHDEDSTDAEISKIDFAQHYYEVNMRNKKKRPSSGACTESGGSSGGVALERERPMSWEGELSDSEMVIDTPNHNDENSSSLDLQSSRDSIETLRNVTIKTEPMKADRLEAFQSLDDQHVLDLKYKSNLSQPLQQHQRSLSMNRISVLTDTASLSLARRPSSPSANGKSSLVLSSDQKNIPVIIPASANSEVQNLTVKKENIPQQTQLSELKCEPSSVPMDKLLGALHGSPLLGRLPRVLSSASTDSAVHSMYTHSVYSSPSASPRASRQYTPSLSRNNSDASHSSCYSYSSEFSPTHSPVQSRHPHGVVYREATAASGVFPASPAQDDDAELSEDRLHHHQGVSRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYMCLRGGNCPVTVATRKKCPACRFDKCLGCGMKLEAIREDRTRGGRSTYQCSYTLSGAASTGSLLSAHAPATLRHATSLNSVNGPASYNSRGESSSSRATPDIPPLLQEIMDVEHLWQYNESELSRLGRGSGGSGGSAAANPLLAASGITAHSTNPDFLADLCNIADHRLYKIVKWCKSLPLFKNISIDDQICLLINSWCELLVLSCCYRGVGSPGEVRVGGSAHGITLQQSAKLGLTPCIERMLSFTEHLRRLRVDRYEYVALKVIVLLTSDAPELREAEKVRASQEKALAALQAYTAAHSPDAPAKFGELLLRIPELQRTCQFFMQVGKEMLNPANKSKDGEGPSFNLLMELLRGDH
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01386822;
- 90% Identity
- iTF_00689445;
- 80% Identity
- iTF_00923801;