Basic Information

Insect: Lucilia sericata
Gene Symbol: L
Assembly: GCA_015586225.1
Location: NW:183401-197895[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 6.9e-06 0.00032 20.7 1.7 1 23 256 278 256 278 0.98

2 19 0.55 26 5.2 5.7 1 23 284 306 284 306 0.98

3 19 3e-07 1.4e-05 25.0 3.1 1 23 312 334 312 334 0.99

4 19 1.4e-05 0.00065 19.7 0.3 1 23 340 362 340 362 0.98

5 19 3.4 1.6e+02 2.8 0.8 2 23 427 450 426 450 0.85

6 19 0.0028 0.13 12.5 0.2 2 23 477 499 476 499 0.96

7 19 0.036 1.7 9.0 0.7 1 23 600 622 600 622 0.97

8 19 0.4 19 5.7 2.0 2 23 630 651 629 651 0.95

9 19 0.0016 0.077 13.2 0.2 1 23 659 683 659 683 0.92

10 19 0.29 13 6.1 0.1 1 19 688 706 688 708 0.93

11 19 5.1 2.4e+02 2.2 0.6 3 23 720 741 718 741 0.84

12 19 0.0018 0.084 13.1 2.9 1 23 780 802 780 803 0.96

13 19 3.9 1.8e+02 2.6 0.9 1 23 973 997 973 997 0.89

14 19 0.001 0.049 13.8 4.8 2 23 1006 1028 1005 1028 0.97

15 19 0.15 7.1 7.0 0.1 1 23 1034 1056 1034 1056 0.92

16 19 0.013 0.61 10.4 0.4 2 23 1064 1085 1063 1085 0.96

17 19 0.98 46 4.5 0.5 2 23 1175 1196 1175 1196 0.94

18 19 0.0022 0.1 12.8 0.0 1 23 1206 1228 1206 1228 0.97

19 19 0.056 2.6 8.4 0.6 1 23 1235 1257 1235 1257 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	6.9e-06	0.00032	20.7	1.7	1	23	256	278	256	278	0.98
2	19	0.55	26	5.2	5.7	1	23	284	306	284	306	0.98
3	19	3e-07	1.4e-05	25.0	3.1	1	23	312	334	312	334	0.99
4	19	1.4e-05	0.00065	19.7	0.3	1	23	340	362	340	362	0.98
5	19	3.4	1.6e+02	2.8	0.8	2	23	427	450	426	450	0.85
6	19	0.0028	0.13	12.5	0.2	2	23	477	499	476	499	0.96
7	19	0.036	1.7	9.0	0.7	1	23	600	622	600	622	0.97
8	19	0.4	19	5.7	2.0	2	23	630	651	629	651	0.95
9	19	0.0016	0.077	13.2	0.2	1	23	659	683	659	683	0.92
10	19	0.29	13	6.1	0.1	1	19	688	706	688	708	0.93
11	19	5.1	2.4e+02	2.2	0.6	3	23	720	741	718	741	0.84
12	19	0.0018	0.084	13.1	2.9	1	23	780	802	780	803	0.96
13	19	3.9	1.8e+02	2.6	0.9	1	23	973	997	973	997	0.89
14	19	0.001	0.049	13.8	4.8	2	23	1006	1028	1005	1028	0.97
15	19	0.15	7.1	7.0	0.1	1	23	1034	1056	1034	1056	0.92
16	19	0.013	0.61	10.4	0.4	2	23	1064	1085	1063	1085	0.96
17	19	0.98	46	4.5	0.5	2	23	1175	1196	1175	1196	0.94
18	19	0.0022	0.1	12.8	0.0	1	23	1206	1228	1206	1228	0.97
19	19	0.056	2.6	8.4	0.6	1	23	1235	1257	1235	1257	0.95

Sequence Information

Coding Sequence: ATGATggctttaaaaatgttataccGTGGGCCCAGTTCAagattagaaaatttaattgaaaaaattcaaGCCACCAAGGAAATTGTTAATGCcgacatGTACTCGACACATACATCGTCAAGTTATTCACCTTCAATATCAGATGGTACTATGACACCAAATTCTTTACATCATCATCAACACCACCATCATCAGCAGCATTTAGTTATACCACCGCATTTACCCTTTCCCAATACGACTGCTTATGAGGAAGACAACAACACAACGTCTTCGTTGGCCCTACAGACACAACGTCTGCACAGACAACAAAAAACCAATGGCACTTTGGATGGCGCTGACTATGAAGACAACGCCAATGACAATGACAACGACCACAATAACGAAAGGATTCACAAAAATGATACAAAATTATGTGAAGACAACAACGACGATACAATTGTTGCAGACAATAAGACAACCGCAAATATTCACGAAAGTGGCGATGAacatcatcagcaacaacagcagccgcACCATCAACATCATCAACTTAAACGTCATGGTCGTCATCATCGTTATGCTGAACATGCCTTAAGAATTCCTTCAAAATTACGTAAAATCGATAGGGATTCAGCGGTTGGTAATGGTGCTACTATAACTACAACTAATACGACTACTGCTGCTGGTGGTGTTGTTGGAGGTGTAACAACAAATGCAGTCAAGTTTGATAAGTTGACAGGAGATGGTATTAAAAGTGGTAACAATGCTGCCAGTGCCGACGGATCCTATCAATGTCAATTCTGTGATAAATCATTTCCGCGTCTTGGTTATTTGAAAAAACATGAACAGAGTCATGCTGAACACTTGCCCTTTAAATGTGAATACTGTGCTCGTCTCTTTAAGCACAAGCGTTCTCGTGATCGTCATACTAAATTGCATACAGGCGATCGTCGCTATCGTTGTCCTCATTGTGAGGCCGCTTTCTCAAGaagCGATCACTTAAAGATCCATATGAAAACTCACGACAACCAAAAACCATTTCAATGTACCATTTGCAATCGAGGCTACAATACAGCGGCTGCTCTTACATCACATAtgcaaaatcataaaaaacaagCGGCTCTTCTAGCTGCTGGTGGTAATCCTCAAGCTCTTAATTATAGTCCACGTTCTACGGGTTCGGCTTCTAGTAATGGCAGTTTACAGAAACGGCGTTACGGTTTAGCAGCAGCCTCCGAACAGAGTCCAAATCGTCTTGACTATCCAAAACGAGGACGTTCCTCTTCGTCGAATATGCTTAAGTGTACATTCTGCTCAAAGTCCGATTTTACTGCCGTAGAACAGTTAAACAATCATCTACAAACTCAACATGAAAAAGAATTGGCTCATTCTATGACTCCTCCTTCCACTAACAACAATCAAGCTTTAGATAATCACGCCTTCCAGCTATCGTGTGAATATTGTACCATGAAGTTTCCCAATATTGCTGCCATGTTCCAGCATATGCGCTCAGCTCACTTGGATCGTTTGACTAGTCCTAATTCATACTTTGAACATTTTAATCGTCTGGCAGCCTCGGGCACCTTTAGTCCACGTTTATTAACAGGGCCTCCTTTAAGAAGTGCAGCCAGTGCCGAGGAGAACAGCATTAAAGAAGAACACAATTTATCAAGTCCTAAATCGGTGGAAGCTGTTACACGTCAAAGTGAAGATGAACCTACCGATCTAAGCCAAAATAACCGTAGATCAATGACACCTACAAATACTCCTCAGAATTCTCCTCAAGAAAATTTCTCCACCAACGAAAAACCAGGTTTATTCTTCTGCAATCAATGTAACGCTGGTTTACCCGATTTCGAATCTTTTCGCAATCACTTGAAAACCCACATTGCCCAGGGTCTCAATCTAGTGTGTCATCATTGCGGCCTGCTATTGAGGGAGCATGCTGAGTACGAAAGACATGTTATTTCACATTTCCTAATAACAAATTCTGAGTACAATTGTGCGGGTAACTGCCAGAAGTCTTTTGGAAAGCCGGAGGAATTACAAAAACATCTTTTGGATCAACATGCCATAACAATGTTCAAATGTGGTCTTTGCAGTGAAATGTTTGAATCGAAAGTGGCCATACAAGTGCATTTTGCCTGCACACACTCCGCAGAAACCAAAATCCTAAGATGCTCCGCCTGCATGGATGTATTTAGGAcggaaaatgattttaacttGCATGTTAAAACTCGTCATCAAGCGGTAAATAATGCACCAGCTCCCGTAAATTCTTTGCAGTGCATGTTTTGTCGTACAGTATGTTCCTCTGATTTGGAAATGCAGTTCCATTTGGCAGCCCATGCTAGACAATTTCGTTGTCCTTCCTGCCCGGAAACTTTCCATGTTGAATTCTTACTCGATCGCCATATGCAAACACATCATGGAGGCTTAGAACGTCCTCCACCACCACCGCCTCCAGCAGCTCCATCTATTGGCGAAGAACATACATCTCCTGTTCCCAATCCTAATGCTATATCTCCCATGAATTCCTTATATGTGAATGCTCTATTTGGCAAATCACCGTTAATGCCGCTGGCaccacaaaataataataacagtaTATTGGATTATAACATGGCATTTGCCTCACATCTCAATAAGGGTCTATTTCCCAATACCACACCCAACAAGTTTTACAATCCTCTACAAATTGACACAAATGCCATGAAACACTCTGCCCTAATGTACGGTTTGTCACAGAGATATTTCGATACTAACCGCACCGTAATGGAAATgtatcaacaacagcagcagcaacaacaacaacatcatcaggAAAATAACAAAACGCCGGGTAACTATTTTATTAGCCCCAAACAACCATCAGCTGGACCTCATGATGTTCATCATCGCAACGATATGCCTGCTTCCCCCATTAACAATACCGGTTTCAGTTGTGGCATTTGTGAACGCAACGATTTTCGCACCGAGTCAGAAGTTCACTCACATCGCAAGATTGTACATAATCTTAAGACGGGGGTTAGTTTAAAGTGTGCCTATTGCTCGGGTAACTTTAAGTCACGCAGTGAATTGGAGCATCATATGAAAACCTGTCACAATTCTACTGGCAAACACAAATGTTTGATCTGCGATGAAATCTTTCCCTCACCAGCCATATTGGCCGAACATAAATTGCAACATTCCAAGGTGGGACAATCGGGAAAATGTTCTCACTGTTCCAAGGCATTGGCCGATGTTAGTGCATTTAAGGCTCATTTATCCGAACACAATACAGAAGGTCAAATGCCAGTACAGTGTATCTGTTGTCGCCAGTCTTTACATTCCGAATTTGAGATTGGACTGCATGCCAAATTCCATGTTAAAAACTCCACTGTTCAGGAAAATGTTTGTGCTCTTTGCCTAGAACCCATTACCAATTCACCCACTGAAGCCAAAGTATGTGAAAAATGTTGTCGCAAGCATAATCTCAATACAAAATTCAAGCAACGCGAGCATTTTGAACGTCCCGCCGAGCTAAGGCAATTTATTGAAAACCGTTGCAATCTTTGCAAAATGATTTTACCACATGCTCAAAAACTCCAAGAACACTTGGTCGAACACACCTTTGCCGGTTGCGAGGATAGGGGCTTCAATTGTTACATCTGTTCGGCAGTTTTTACGGCACCAAGTGGTCTACTTAATCATATGCTCGAGCATGGTGTTAACTCCAAGCCTTATGATTGTAATTTATGTCCTGAGAAATACTATTTCCGCGCTGAATTAGATCATCATCTAATCGATCATGATTTAAGACAATCTCCCACTGCAGTTAAAAACGAGCAAGAGCAATTGACACCTAAAGAAGATACTGGCATGAAACCAGAGAAACCTGCCGAAAGATTAAATGAGGTTAAGCAAGAAGTAATTGAAACTGATCATAATTCTAATGTGGCTGATGAAGATGAATACATAGAGGTGGAAAAGGTAAATgagaataacaacaataacaatcagTTGGATGATACAGTATCGAATAAAACTGAAGAGTCCAAAGAGAAATCAACTGAACATATCAGAGATGAAAAGGCATAA
Protein Sequence: MMALKMLYRGPSSRLENLIEKIQATKEIVNADMYSTHTSSSYSPSISDGTMTPNSLHHHQHHHHQQHLVIPPHLPFPNTTAYEEDNNTTSSLALQTQRLHRQQKTNGTLDGADYEDNANDNDNDHNNERIHKNDTKLCEDNNDDTIVADNKTTANIHESGDEHHQQQQQPHHQHHQLKRHGRHHRYAEHALRIPSKLRKIDRDSAVGNGATITTTNTTTAAGGVVGGVTTNAVKFDKLTGDGIKSGNNAASADGSYQCQFCDKSFPRLGYLKKHEQSHAEHLPFKCEYCARLFKHKRSRDRHTKLHTGDRRYRCPHCEAAFSRSDHLKIHMKTHDNQKPFQCTICNRGYNTAAALTSHMQNHKKQAALLAAGGNPQALNYSPRSTGSASSNGSLQKRRYGLAAASEQSPNRLDYPKRGRSSSSNMLKCTFCSKSDFTAVEQLNNHLQTQHEKELAHSMTPPSTNNNQALDNHAFQLSCEYCTMKFPNIAAMFQHMRSAHLDRLTSPNSYFEHFNRLAASGTFSPRLLTGPPLRSAASAEENSIKEEHNLSSPKSVEAVTRQSEDEPTDLSQNNRRSMTPTNTPQNSPQENFSTNEKPGLFFCNQCNAGLPDFESFRNHLKTHIAQGLNLVCHHCGLLLREHAEYERHVISHFLITNSEYNCAGNCQKSFGKPEELQKHLLDQHAITMFKCGLCSEMFESKVAIQVHFACTHSAETKILRCSACMDVFRTENDFNLHVKTRHQAVNNAPAPVNSLQCMFCRTVCSSDLEMQFHLAAHARQFRCPSCPETFHVEFLLDRHMQTHHGGLERPPPPPPPAAPSIGEEHTSPVPNPNAISPMNSLYVNALFGKSPLMPLAPQNNNNSILDYNMAFASHLNKGLFPNTTPNKFYNPLQIDTNAMKHSALMYGLSQRYFDTNRTVMEMYQQQQQQQQQHHQENNKTPGNYFISPKQPSAGPHDVHHRNDMPASPINNTGFSCGICERNDFRTESEVHSHRKIVHNLKTGVSLKCAYCSGNFKSRSELEHHMKTCHNSTGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCSHCSKALADVSAFKAHLSEHNTEGQMPVQCICCRQSLHSEFEIGLHAKFHVKNSTVQENVCALCLEPITNSPTEAKVCEKCCRKHNLNTKFKQREHFERPAELRQFIENRCNLCKMILPHAQKLQEHLVEHTFAGCEDRGFNCYICSAVFTAPSGLLNHMLEHGVNSKPYDCNLCPEKYYFRAELDHHLIDHDLRQSPTAVKNEQEQLTPKEDTGMKPEKPAERLNEVKQEVIETDHNSNVADEDEYIEVEKVNENNNNNNQLDDTVSNKTEESKEKSTEHIRDEKA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01237143;
90% Identity: iTF_00045671;
80% Identity: -