Lser001174.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Lucilia sericata
Gene Symbol
-
Assembly
GCA_015586225.1
Location
NW:93897-100907[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.021 0.99 9.7 0.1 2 23 239 261 238 261 0.91
2 10 0.24 11 6.4 0.0 6 23 270 287 270 287 0.97
3 10 0.00011 0.0053 16.9 0.4 1 23 293 316 293 316 0.97
4 10 0.00086 0.04 14.1 4.8 1 23 326 348 326 348 0.99
5 10 0.0066 0.31 11.3 2.4 2 23 355 377 354 377 0.95
6 10 0.00019 0.009 16.1 3.1 1 23 383 405 383 405 0.94
7 10 5.4 2.5e+02 2.1 0.4 2 23 414 435 413 435 0.79
8 10 5.6e-06 0.00026 21.0 1.2 3 23 442 463 441 463 0.95
9 10 2e-07 9.4e-06 25.5 0.5 2 23 470 491 469 491 0.96
10 10 6.2e-05 0.0029 17.7 3.5 1 23 497 520 497 520 0.98

Sequence Information

Coding Sequence
ATGATTTGTCGTCTATGTTTAAAAGACATTCCAAAAGAATCCAGCATtaaattgtatgaaaatttaGACACATCAAGTGATTCCCTAGAAATGGTCAAACTAATCGAAAAGTATTTGGAAATTGAAATTAAACAGAACGACATTGTATCGACTATTATATGTCAAGATTGTTATGATCACTTGGAAGAGTTTCATCGATTTTCGCAACAAGTGGCTGAGAAGCAGCTAACACTGCGTAATGAGTTTATGGATGTAAATCTTAAGaaagaatttaattttgatgatgatggtgatgctTGGGACAATGATGATCATGAGGATAAAATTGAAATGGATCCGAAAGAAACTACACAAATGACCATTAACTGTCCGATAAGTATGTTTAAGGATGAATcggataatgatgatgataatgacgaAAAGGAAATGCCTACAGAGGACTTAATGGATACTGTTATAGGTAATGTGGAGAAAGACATTATAGCACCTGATAGTGTAGCGGTCAATGAAGAAGAGGATGATGATTACTTACCAGATCAAATTTCTTCGGAAGATGATGATGTGcccttaataaaacttaaatccaCTAAGAAAACGAAGAACGCAAAAACAAAACGTAAAAAAGCTCCTGCAAAACCTCGCGAGATTAAAGAGAAGAAACCAGCTAAAAAGAAATTATCCGCACAAGAAGAAGTGGCCATGTCTATGGATCTAGTATGTGATATTTGTCAGACACGCGTTGAAACCTGGAAGGCATTAAGAGAACACTTTCTGCTGGCACATACCAAGACACCCTATATTAAATGCTGTGACATTACCTATCGTAAACCACGAGAACTTATTGAACATCTTGAGTGGCACAAAAATCCGGATATGTTTAAATGTCAAATTTGTGATAAAAATATGTCGAGTGCTCGTAATCTAACTATACATATAACTTCAGAACATCCCGATGAAGCTGATTCAGTTGAATTCTACGAGTGCGAACACTGTTCCAAACGTATACGCAATTATAATCTATTTAAGAAGCATTTACGTTCTCACAACAAAGATAAAGAAGTTGAATGTCATATTTGCAATAAAAGATGTGCAACTATATATCGTTTTCGAAATCATATTGCATCCGTACACAATGACATCTACCGTCATATCTGTGATATTTGTGGCAAGAAATtcaaatcgaaaattttttttcaaaaacactaCGACGAACATCAGGGCATTGTCGATCCACCCGTACAATGTACCATCTGCCAAAAGTGGCTTAAAAACATACGCGTACTTCGACTGCATCGTTTTGAGCATGAGAAACATCCTGCAGCATGCAATATATGTGGAAAAGTATTTGAAACCAAACATAGATTGCGTCGGCACATATCCTATTGGCATAATTCTGATGTAAATTTGCAATGCAGCTATTGTGATAAAGTTTTTCGACAAGAACGCAATCTAAAAGAACATATGGCGATACATACGGGAGAACAGCTTTATAAATGTCCTCACTGTCAAAAGGAGTCACGTTCCAGAtcaaatatgtatgttcatatAAAGAGACAACATCCTGCAGAATGGTGGAAATCGAAAATGGAACGTTTAAATATAGATTTAAACACAGTTAATCCTTAA
Protein Sequence
MICRLCLKDIPKESSIKLYENLDTSSDSLEMVKLIEKYLEIEIKQNDIVSTIICQDCYDHLEEFHRFSQQVAEKQLTLRNEFMDVNLKKEFNFDDDGDAWDNDDHEDKIEMDPKETTQMTINCPISMFKDESDNDDDNDEKEMPTEDLMDTVIGNVEKDIIAPDSVAVNEEEDDDYLPDQISSEDDDVPLIKLKSTKKTKNAKTKRKKAPAKPREIKEKKPAKKKLSAQEEVAMSMDLVCDICQTRVETWKALREHFLLAHTKTPYIKCCDITYRKPRELIEHLEWHKNPDMFKCQICDKNMSSARNLTIHITSEHPDEADSVEFYECEHCSKRIRNYNLFKKHLRSHNKDKEVECHICNKRCATIYRFRNHIASVHNDIYRHICDICGKKFKSKIFFQKHYDEHQGIVDPPVQCTICQKWLKNIRVLRLHRFEHEKHPAACNICGKVFETKHRLRRHISYWHNSDVNLQCSYCDKVFRQERNLKEHMAIHTGEQLYKCPHCQKESRSRSNMYVHIKRQHPAEWWKSKMERLNIDLNTVNP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00259126; iTF_00045531; iTF_00259997;
90% Identity
-
80% Identity
-