Basic Information

Gene Symbol
-
Assembly
GCA_001187945.1
Location
JRES01001693.1:59244-60777[-]

Transcription Factor Domain

TF Family
zf-LITAF-like
Domain
zf-LITAF-like domain
PFAM
PF10601
TF Group
Zinc-Coordinating Group
Description
Members of this family display a conserved zinc ribbon structure [3] with the motif C-XX-C- separated from the more C-terminal HX-C(P)X-C-X4-G-R motif by a variable region of usually 25-30 (hydrophobic) residues. Although it belongs to one of the zinc finger's fold groups (zinc ribbon), this particular domain was first identified in LPS-induced tumour necrosis alpha factor (LITAF) which is produced in mammalian cells after being challenged with lipopolysaccharide (LPS)[2]. The hydrophobic region probably inserts into the membrane rather than traversing it. Such an insertion brings together the N- and C-terminal C-XX-C motifs to form a compact Zn2+-binding structure [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 1.8e-12 2.3e-09 36.9 13.4 2 68 54 123 53 125 0.86
2 3 5.9e-05 0.076 12.9 1.6 1 22 166 187 166 193 0.90
3 3 6.2e-05 0.08 12.8 1.1 52 70 191 209 187 209 0.87

Sequence Information

Coding Sequence
ATGGCTACAATTAACGAACAGAAGCCAGCCAATGTTGAGGTGGTCATTGACAAAAAAGCACAAAAGGCAGGAGAAAAAATGTTGCGCGCCCAAAGGGATCAAGAAATTTACAATAACTTTGCCACGCCTCTTGTGGGCACCTTCTTAAATCTAACACAAGAACCGGCTTTAATTAAATGTCCCAGTTGTGGCGTAGAGGAAATGAGTGAAGTGGTTGATGAATTAAAATGGTGGGCCACTGAAATTAATCGGTTTCTGGGATGTTTGTTTGtaacattgtgctgctgttgctgcttgGATTATAGTCTGCCCTGCAAATCCAGTGATCGTAATCATTATTGCAAAAATTGTGGCTGCTATTTTGGGAGAGCCATGCGAATTCCTCCCCTTAAGAAAGTCAAAATGCGTAAGCAGTTAAAATCATTGTCTGCTATCTGGCGCGTTAACATCATGGAAAACGAAACTTTACCACCACCTGTGTATTTTGCTGTCGGCCCTCAACCCCATGAAGTTTCATGtccattttgtaaacaatatagTAAAACAACTATGAAACGTTCATTTTTTCGCTGCTCTTTACGACGTCATTATTGTTCCCACTGTGGCGAATATTTGGGTTCCTATAGACGTCCTCAGTTGTAG
Protein Sequence
MATINEQKPANVEVVIDKKAQKAGEKMLRAQRDQEIYNNFATPLVGTFLNLTQEPALIKCPSCGVEEMSEVVDELKWWATEINRFLGCLFVTLCCCCCLDYSLPCKSSDRNHYCKNCGCYFGRAMRIPPLKKVKMRKQLKSLSAIWRVNIMENETLPPPVYFAVGPQPHEVSCPFCKQYSKTTMKRSFFRCSLRRHYCSHCGEYLGSYRRPQL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00900215;
90% Identity
-
80% Identity
-